2025
Alpha rhythm and Alzheimer’s disease: Has Hans Berger’s dream come true?
Babiloni C, Arakaki X, Baez S, Barry R, Benussi A, Blinowska K, Bonanni L, Borroni B, Bayard J, Bruno G, Cacciotti A, Carducci F, Carino J, Carpi M, Conte A, Cruzat J, D'Antonio F, Della Penna S, Del Percio C, De Sanctis P, Escudero J, Fabbrini G, Farina F, Fraga F, Fuhr P, Gschwandtner U, Güntekin B, Guo Y, Hajos M, Hallett M, Hampel H, Hanoğlu L, Haraldsen I, Hassan M, Hatlestad-Hall C, Horváth A, Ibanez A, Infarinato F, Jaramillo-Jimenez A, Jeong J, Jiang Y, Kamiński M, Koch G, Kumar S, Leodori G, Li G, Lizio R, Lopez S, Ferri R, Maestú F, Marra C, Marzetti L, McGeown W, Miraglia F, Moguilner S, Moretti D, Mushtaq F, Noce G, Nucci L, Ochoa J, Onorati P, Padovani A, Pappalettera C, Parra M, Pardini M, Pascual-Marqui R, Paulus W, Pizzella V, Prado P, Rauchs G, Ritter P, Salvatore M, Santamaria-García H, Schirner M, Soricelli A, Taylor J, Tankisi H, Tecchio F, Teipel S, Kodamullil A, Triggiani A, Valdes-Sosa M, Valdes-Sosa P, Vecchio F, Vossel K, Yao D, Yener G, Ziemann U, Kamondi A. Alpha rhythm and Alzheimer’s disease: Has Hans Berger’s dream come true? Clinical Neurophysiology 2025, 172: 33-50. PMID: 39978053, DOI: 10.1016/j.clinph.2025.02.256.Peer-Reviewed Original ResearchConceptsPathological agingAlzheimer's diseaseExpert panelAlpha rhythmAD patient’s qualityQuality of lifeAging-Alzheimer's AssociationCognitive impairmentCognitive declineClinical workupNeuroscience SocietyCortical circuitsAD patientsUS National InstitutesOlder adultsRoutine useSenile dementiaDecades of researchPatients' qualityClinical guidelinesOscillatory synchronizationCause of dementiaClinical applicationNIA-AADementia
2024
Comparing the Accuracy and Reliability of ABC/2 and Planimetry for Vestibular Schwannoma Volume Assessment
Singh K, Abdou H, Panth N, Chiang V, Buono F, Schwartz N, Mahajan A. Comparing the Accuracy and Reliability of ABC/2 and Planimetry for Vestibular Schwannoma Volume Assessment. Otology & Neurotology 2024, 46: 196-200. PMID: 39792983, DOI: 10.1097/mao.0000000000004392.Peer-Reviewed Original ResearchConceptsTumor volume assessmentABC/2 methodVestibular schwannomaVolume assessmentPlanimetry methodTumor volumeTumor volume changesFollow-up scansOverestimate tumor volumePatients' quality of lifeTumor sizeRetrospective reviewIntracranial tumorsImprove clinical decision makingSubgroup analysisVolumetric assessmentTumorClinical decision makingQuality of lifePatients' qualityPatientsClinical settingPlanimetryImaging techniquesPositive correlationPelvic Floor Physical Therapy Prehabilitation (PrePFPT) for the prevention of low anterior resection syndrome
Coppersmith N, Schultz K, Esposito A, Reinhart K, Ray E, Leeds I, Pantel H, Reddy V, Longo W, Mongiu A. Pelvic Floor Physical Therapy Prehabilitation (PrePFPT) for the prevention of low anterior resection syndrome. Surgical Oncology Insight 2024, 1: 100097. DOI: 10.1016/j.soi.2024.100097.Peer-Reviewed Original ResearchLow anterior resection syndromeAnterior resection syndromePelvic floor physical therapyQuality of life outcomesSymptoms of low anterior resection syndromeImprove patient qualityPhysical therapyRectal cancerPrehabilitationDevelopment of low anterior resection syndromeStudy designTreatment of low anterior resection syndromeTreatment of rectal cancerIncidence of low anterior resection syndromeLife outcomesEvaluated pre-Patients' qualityRectal cancer patientsCancer patientsDevelopment of symptomsNeoadjuvant chemoradiotherapyDefecatory dysfunctionImproved recoveryInternational trialsSyndromeThe 3 Ds: Depression, Dysbiosis, and Clostridiodes difficile
Boustany A, Feuerstadt P, Tillotson G. The 3 Ds: Depression, Dysbiosis, and Clostridiodes difficile. Advances In Therapy 2024, 41: 3982-3995. PMID: 39276186, PMCID: PMC11480130, DOI: 10.1007/s12325-024-02972-0.Peer-Reviewed Original ResearchIncreased risk of C. difficile infectionRisk of C. difficile infectionClasses of antidepressantsClostridioides difficile infectionNovel treatment optionsPatients' quality of lifeMicrobiome-related factorsDevelopment of dysbiosisOpportunistic infectionsRecurrent CDIGut microbiomeRecurrence rateAntidepressant useDifficile infectionMental disordersTreatment optionsLive biotherapeutic productsComplex pathophysiologyIncreased riskC. difficileGut dysbiosisQuality of lifePatients' qualitySignificant healthcare concernAntidepressantsUsing Neuromodulators for Salivary, Eccrine, and Apocrine Gland Disorders
Rajanala S, Salame N, Dover J. Using Neuromodulators for Salivary, Eccrine, and Apocrine Gland Disorders. Dermatologic Surgery 2024, 50: s103-s111. PMID: 39196843, DOI: 10.1097/dss.0000000000004262.Peer-Reviewed Original ResearchConceptsQuality of lifeParasympathetic cholinergic neuronsBotulinum toxinLong-term treatmentPatients' quality of lifeTreatment of sialorrheaBotulinum toxin serotype ABotulinum toxin treatmentToxin serotype AImpact patient healthStandard doseGlandular disordersOff-labelOnabotulinumtoxin AIncobotulinumtoxin AAxillary hyperhidrosisNoninvasive treatmentPatient healthApplication of neuromodulationCholinergic neuronsPatients' qualityApocrine glandsHyperhidrosisSerotype BToxin treatmentEmbracing cancer complexity: Hallmarks of systemic disease
Swanton C, Bernard E, Abbosh C, André F, Auwerx J, Balmain A, Bar-Sagi D, Bernards R, Bullman S, DeGregori J, Elliott C, Erez A, Evan G, Febbraio M, Hidalgo A, Jamal-Hanjani M, Joyce J, Kaiser M, Lamia K, Locasale J, Loi S, Malanchi I, Merad M, Musgrave K, Patel K, Quezada S, Wargo J, Weeraratna A, White E, Winkler F, Wood J, Vousden K, Hanahan D. Embracing cancer complexity: Hallmarks of systemic disease. Cell 2024, 187: 1589-1616. PMID: 38552609, DOI: 10.1016/j.cell.2024.02.009.Peer-Reviewed Original ResearchConceptsHuman genetic variationSystemic diseaseHallmarks of cancerTumor-related thrombosisGenetic variationGene-environment interactionsCancer-related deathsComplexity of cancerMolecular basisTreat human cancersNervous system interactionsMechanisms of carcinogenesisHuman cancersImprove patient qualityCancer cachexiaSystemic manifestationsTumor micro-Cancer outcomesDistant organsTumor initiationMolecular oncologyTumorPatients' qualityPrevent cancerCancerApplication of the Sleep C.A.L.M. Tool for Assessing Nocturia in a Large Nationally Representative Cohort
Boroda J, De Leon B, Khosla L, Chobufo M, Rahman S, Lazar J, Weiss J, Monaghan T. Application of the Sleep C.A.L.M. Tool for Assessing Nocturia in a Large Nationally Representative Cohort. International Neurourology Journal 2024, 28: s55-61. PMID: 38461857, PMCID: PMC10932577, DOI: 10.5213/inj.2346258.129.Peer-Reviewed Original ResearchOdds of nocturiaNational Health and Nutrition Examination SurveyHealth and Nutrition Examination SurveySex subgroupsCommunity-dwelling adultsNutrition Examination SurveyAssociated with greater oddsAssociation of nocturiaAssociated with increased oddsNationally representative cohortDose-dependent fashionImpact patient qualityQuality of lifePhysical examination dataYears of ageAssess nocturiaNighttime voidsExamination SurveyNationally representative datasetNocturiaRepresentative cohortRetrospective analysisGreater oddsPertinent questionnairesPatients' quality
2023
Dichloroacetate as a novel pharmaceutical treatment for cancer-related fatigue in melanoma
Zhang X, Lee W, Leitner B, Zhu W, Fosam A, Li Z, Gaspar R, Halberstam A, Robles B, Rabinowitz J, Perry R. Dichloroacetate as a novel pharmaceutical treatment for cancer-related fatigue in melanoma. AJP Endocrinology And Metabolism 2023, 325: e363-e375. PMID: 37646579, PMCID: PMC10642987, DOI: 10.1152/ajpendo.00105.2023.Peer-Reviewed Original ResearchConceptsCancer-related fatigueNovel pharmaceutical treatmentsPhysical functionPharmaceutical treatmentTumor growthCancer treatmentStandard cancer treatmentTumor-bearing miceLate-stage tumorsEffective pharmaceutical treatmentMurine cancer modelsNew metabolic targetsMultiple cancer typesAdjuvant therapyCommon complicationPatients' qualitySymptom managementClinical trialsMurine modelPotential therapyPharmaceutical therapySmall molecule inhibitorsCancer modelDCA treatmentLactate concentrationA Deep Learning Onion Peeling Approach to Measure Oral Epithelium Layer Number
Zhang X, Gleber-Netto F, Wang S, Jin K, Yang D, Gillenwater A, Myers J, Ferrarotto R, Pickering C, Xiao G. A Deep Learning Onion Peeling Approach to Measure Oral Epithelium Layer Number. Cancers 2023, 15: 3891. PMID: 37568707, PMCID: PMC10416878, DOI: 10.3390/cancers15153891.Peer-Reviewed Original ResearchOral epitheliumNeck squamous cell carcinomaSquamous cell carcinomaPatients' qualityCell carcinomaDysplasia severityEarly diagnosisPathologist's examinationOral cavityComplex cancersClinical relevanceDysplasia diagnosisSurvival analysisEpithelium layerDiagnostic potentialCell layerIntra-observer variationDiagnosisEpitheliumClose correlationPotential additionPrognosisCarcinomaCancerClinical Features and Management of Acute and Chronic Radiation-Induced Colitis and Proctopathy
Abu-Sbeih H, Tang T, Ali F, Ma W, Shatila M, Luo W, Tan D, Tang C, Richards D, Ge P, Thomas A, Wang Y. Clinical Features and Management of Acute and Chronic Radiation-Induced Colitis and Proctopathy. Cancers 2023, 15: 3160. PMID: 37370770, PMCID: PMC10296205, DOI: 10.3390/cancers15123160.Peer-Reviewed Original ResearchArgon plasma coagulationRadiation therapyMedical managementAPC treatmentSingle tertiary cancer centerRadiation-induced colitisManagement of AcuteNon-bloody diarrheaRetrospective observational studyTertiary cancer centerCancer patients' qualityLogistic regression analysisClinical characteristicsEndoscopic therapySymptom onsetPredominant symptomClinical featuresEndoscopic characteristicsPatients' qualityCancer CenterClinical variablesBloody diarrheaCancer patientsFemale sexFrequent findingEstimation of moral distress among nurses: A systematic review and meta-analysis
Alimoradi Z, Jafari E, Lin C, Rajabi R, Marznaki Z, Soodmand M, Potenza M, Pakpour A. Estimation of moral distress among nurses: A systematic review and meta-analysis. Nursing Ethics 2023, 30: 334-357. PMID: 36704986, PMCID: PMC9902807, DOI: 10.1177/09697330221135212.Peer-Reviewed Original ResearchConceptsSystematic reviewPublication biasMoral distressNewcastle-Ottawa checklistSTATA software version 14Small-study effectsMean scoreRandom-effects modelPatients' qualityPROSPERO databaseSubgroup analysisBegg's testMedical CenterMethodological qualityFunnel plotVersion 14NursesTotal scoreSystematic searchProfessional nursesISI WebNurses' workplaceConfidence intervalsHigh levelsDistress
2022
Cerebrospinal Fluid Drainage for Prevention of Spinal Cord Ischemia in Thoracic Endovascular Aortic Surgery—Pros and Cons
Ellauzi H, Arora H, Elefteriades J, Zaffar M, Ellauzi R, Popescu W. Cerebrospinal Fluid Drainage for Prevention of Spinal Cord Ischemia in Thoracic Endovascular Aortic Surgery—Pros and Cons. Aorta 2022, 10: 290-297. PMID: 36539146, PMCID: PMC9767776, DOI: 10.1055/s-0042-1757792.Peer-Reviewed Original ResearchIn the face of change: Which coping strategies predict better psychosocial outcomes in face transplant recipients?
Nizzi M, Pomahac B. In the face of change: Which coping strategies predict better psychosocial outcomes in face transplant recipients? Frontiers In Psychology 2022, 13: 995222. PMID: 36467137, PMCID: PMC9712221, DOI: 10.3389/fpsyg.2022.995222.Peer-Reviewed Original ResearchBetter mental healthPsychosocial outcomesMental healthLong-term psychosocial outcomesPre-transplant assessmentPost-transplant phasePost-transplant dataTerm psychosocial outcomesQuality of lifePoor mental healthMental health trajectoriesBetter psychosocial outcomesFace transplant recipientsTransplant recipientsTransplant candidatesMeasures of depressionPatients' qualityCoping strategiesPatientsPsychosocial functioningHealth trajectoriesMonthsOptimal outcomesPromising targetOutcomesFunctional and Symptomatic Clinical Trial Endpoints The HFC-ARC Scientific Expert Panel
Psotka M, Abraham W, Fiuzat M, Filippatos G, Lindenfeld J, Ahmad T, Felker G, Jacob R, Kitzman D, Leifer E, Lewis E, Mentz R, Nkulikiyinka R, Ni W, Schaber D, Sharma A, Solomon S, Stockbridge N, Teerlink J, Unger E, Whellan D, Wittes J, Anker S, O'Connor C. Functional and Symptomatic Clinical Trial Endpoints The HFC-ARC Scientific Expert Panel. JACC Heart Failure 2022, 10: 889-901. PMID: 36456063, DOI: 10.1016/j.jchf.2022.09.012.Peer-Reviewed Original ResearchConceptsAcademic Research ConsortiumHeart failureSubmaximal exercise tolerancePatient-reported outcomesCardiovascular clinical researchResearch ConsortiumExercise toleranceScientific Expert PanelPatients' qualityFunctional statusClinical trialsLife endpointsConsensus recommendationsClinical utilityDrug AdministrationCardiovascular therapeuticsClinical researchU.S. FoodExpert panelPotential endpointsNational InstituteEvidence generationTrialsEndpointAcademic investigatorsIntense Pulse Light Therapy for Meibomian Gland Dysfunction
Kudrna J, Nguyen C, Vora G. Intense Pulse Light Therapy for Meibomian Gland Dysfunction. Current Ophthalmology Reports 2022, 10: 138-152. DOI: 10.1007/s40135-022-00297-1.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsIntense pulse light therapyMeibomian gland dysfunctionGland dysfunctionLight therapySigns of MGDMore refractory casesSafety/efficacyMechanism of actionRefractory casesPatient selectionPatients' qualityOphthalmologic conditionsTherapeutic approachesConventional treatmentReviewThis articleDysfunctionTherapyEfficacyAntimicrobial effectPhotocoagulationSymptomsDermatologistsRecent literatureConcurrent use of tumor necrosis factor inhibitor and tyrosine kinase inhibitor in ankylosing spondylitis and myeloid neoplasm
Gupta A, Department of Medicine Y, Afinogenova Y, Podoltsev N, Danve A, Section of Rheumatology A, Section of Hematology D. Concurrent use of tumor necrosis factor inhibitor and tyrosine kinase inhibitor in ankylosing spondylitis and myeloid neoplasm. European Journal Of Rheumatology 2022, 9: 215-216. PMID: 35156633, DOI: 10.5152/eurjrheum.2022.21097.Peer-Reviewed Case Reports and Technical NotesMyeloid neoplasmsBiologic disease-modifying agentsTumor necrosis factor inhibitorsTyrosine kinase inhibitor imatinibNecrosis factor inhibitorsAutoimmune rheumatic diseasesDisease-modifying agentsKinase inhibitor imatinibTyrosine kinase inhibitorsMiddle-aged malesRheumatic diseasesFactor inhibitorsPatients' qualityFavorable outcomeHematologic malignanciesInhibitor imatinibBeta rearrangementInfliximabConcurrent useKinase inhibitorsCancer diagnosisPatientsNeoplasmsAppropriate casesInhibitorsCalcium-Permeable Channels Cooperation for Rheumatoid Arthritis: Therapeutic Opportunities
Liang H, Yin H, Li S, Chen Y, Zhao Y, Hu W, Zhou R. Calcium-Permeable Channels Cooperation for Rheumatoid Arthritis: Therapeutic Opportunities. Biomolecules 2022, 12: 1383. PMID: 36291594, PMCID: PMC9599458, DOI: 10.3390/biom12101383.Peer-Reviewed Original ResearchConceptsPathogenesis of RARheumatoid arthritisCalcium-permeable channelsIntra-articular inflammationCommon autoimmune diseaseTreatment of RAEntry of CaDrug targetsSynovial invasionPatients' qualityAutoimmune diseasesNovel drug targetsCartilage damageArthritisTherapeutic opportunitiesPathological processesCalcium signalingInflammationPathogenesisSpecific roleRAHuman cellsTargetCell membraneDiseaseSociety for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of nonmelanoma skin cancer
Silk AW, Barker CA, Bhatia S, Bollin KB, Chandra S, Eroglu Z, Gastman BR, Kendra KL, Kluger H, Lipson EJ, Madden K, Miller DM, Nghiem P, Pavlick AC, Puzanov I, Rabinowits G, Ruiz ES, Sondak VK, Tavss EA, Tetzlaff MT, Brownell I. Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of nonmelanoma skin cancer. Journal For ImmunoTherapy Of Cancer 2022, 10: e004434. PMID: 35902131, PMCID: PMC9341183, DOI: 10.1136/jitc-2021-004434.Peer-Reviewed Original ResearchConceptsNonmelanoma skin cancerClinical practice guidelinesImmune checkpoint inhibitorsCutaneous squamous cell carcinomaMerkel cell carcinomaBasal cell carcinomaCell carcinomaPractice guidelinesSkin cancerCancer clinical practice guidelinesCancer care professionalsManagement of toxicitiesSpecial patient populationsSquamous cell carcinomaImmunotherapy of cancerConsensus-based recommendationsOwn clinical experienceRoutine clinical useCheckpoint inhibitorsMetastatic diseasePatient selectionPatients' qualityImmunotherapeutic treatmentPatient populationAggressive subtypeRegional analgesia for cardiac surgery
Grant M, Gregory A, Ouanes J. Regional analgesia for cardiac surgery. Current Opinion In Anaesthesiology 2022, 35: 605-612. PMID: 35900740, DOI: 10.1097/aco.0000000000001169.Peer-Reviewed Original ResearchConceptsCardiac surgeryRegional analgesiaRegional techniquesCardiac surgical settingChest wall blocksOpioid-sparing analgesiaOpioid-sparing approachPain management expertsPerioperative patient careOpioid requirementsOpioid administrationPain controlPain managementPerioperative carePatients' qualityRegional anesthesiaAnalgesiaSurgical settingSurgeryPatient careCareAnesthesiaAdministrationResearch Priorities in Percutaneous Image- and Endoscopy-Guided Interventions for Biliary and Gallbladder Diseases: Proceedings from the Society of Interventional Radiology Foundation Multidisciplinary Research Consensus Panel
Riaz A, Trivedi P, Aadam AA, Katariya N, Matsuoka L, Malik A, Gunn AJ, Vezeridis A, Sarwar A, Schlachter T, Harmath C, Srinivasa R, Abi-Jaoudeh N, Singh H. Research Priorities in Percutaneous Image- and Endoscopy-Guided Interventions for Biliary and Gallbladder Diseases: Proceedings from the Society of Interventional Radiology Foundation Multidisciplinary Research Consensus Panel. Journal Of Vascular And Interventional Radiology 2022, 33: 1247-1257. PMID: 35809805, DOI: 10.1016/j.jvir.2022.06.025.Peer-Reviewed Original ResearchConceptsGallbladder diseaseInterventional radiologyPercutaneous imageConsensus panelAnastomotic biliary stricturesProspective research studyIntraductal cholangiocarcinomaNonsurgical patientsCalculous cholecystitisMultimodality managementPercutaneous drainBiliary stricturesPatients' qualityStent placementClinical relevanceResearch prioritiesDiseaseMultidisciplinary groupTotal durationPatientsManagement protocolCurrent dataUnanswered questionsCholecystitisCholedochoscopy
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