2024
Ultrasound evaluation of portal venous gas and its mimics
Bitar R, Kaur M, Crandall I, McNamara R, Revzin M. Ultrasound evaluation of portal venous gas and its mimics. Abdominal Radiology 2024, 49: 2756-2769. PMID: 38735019, DOI: 10.1007/s00261-024-04328-2.Peer-Reviewed Original Research
2023
EPCO-22. LONGITUDINAL MOLECULAR CHARACTERIZATION IDENTIFIES TREATMENT DRIVEN EVOLUTION OF OLIGODENDROGLIOMA
Chowdhury T, Johnson K, Kocakavuk E, Heo C, Ye G, Ghospurkar P, Wade T, Barnholtz-Sloan J, Costello J, Elliott C, French P, Golebiewska A, Hermes B, Hong C, Horbinski C, Khasraw M, LaViolette P, Li K, Lipp E, Lowman A, McCortney K, Moon H, Ng H, Padovan M, Paek S, Vallentgoed W, Vaubel R, Wesseling P, Westcott K, Consortium G, Varn F, Verhaak R. EPCO-22. LONGITUDINAL MOLECULAR CHARACTERIZATION IDENTIFIES TREATMENT DRIVEN EVOLUTION OF OLIGODENDROGLIOMA. Neuro-Oncology 2023, 25: v128-v128. PMCID: PMC10639435, DOI: 10.1093/neuonc/noad179.0485.Peer-Reviewed Original ResearchWhole-exome sequencingPI3K pathwaySingle-nucleus RNA sequencingStem-like cellsPatient mortalityChromosome 4 lossPIK3R1 mutationsTreatment resistanceFUBP1 mutationsAggressive phenotypeMost oligodendrogliomasOligodendroglioma patientsChromosome arms 1pRecurrenceAdministration dateSomatic copy number alterationsCopy number alterationsMutational signature analysisOligodendrogliomasRecurrent samplesTERT promoterExome sequencingK pathwayCommon mutationsMolecular changesRisk of Contralateral Hip Fracture Following Initial Hip Fracture Among Geriatric Fragility Fracture Patients
Ratnasamy P, Rudisill K, Oghenesume O, Riedel M, Grauer J. Risk of Contralateral Hip Fracture Following Initial Hip Fracture Among Geriatric Fragility Fracture Patients. JAAOS Global Research And Reviews 2023, 7: e23.00001. PMID: 37428152, PMCID: PMC10332831, DOI: 10.5435/jaaosglobal-d-23-00001.Peer-Reviewed Original ResearchConceptsContralateral hip fractureInitial hip fractureKaplan-Meier survival analysisGeriatric hip fracturesHip fractureSurvival analysisFragility fracture patientsIndex hip fractureHip fracture fixationKaplan-Meier analysisBody mass indexMultivariate logistic regressionFracture patientsContralateral fractureIndependent predictorsGeriatric patientsHigh morbidityMass indexPatient mortalityFemale sexNational cohortRisk factorsFracture fixationMultivariate analysisLogistic regression
2022
3D CT-Inclusive Deep-Learning Model to Predict Mortality, ICU Admittance, and Intubation in COVID-19 Patients
Di Napoli A, Tagliente E, Pasquini L, Cipriano E, Pietrantonio F, Ortis P, Curti S, Boellis A, Stefanini T, Bernardini A, Angeletti C, Ranieri S, Franchi P, Voicu I, Capotondi C, Napolitano A. 3D CT-Inclusive Deep-Learning Model to Predict Mortality, ICU Admittance, and Intubation in COVID-19 Patients. Journal Of Imaging Informatics In Medicine 2022, 36: 603-616. PMID: 36450922, PMCID: PMC9713092, DOI: 10.1007/s10278-022-00734-4.Peer-Reviewed Original ResearchConceptsIntensive care unit admittanceIntensive care unit admissionIntensive care unitCOVID-19 patientsDeep learning modelsChest CTLaboratory dataPatient mortalityCT imagesRetrospective multicentre studyReal-time reverse transcriptase polymerase chain reactionHospital admissionReverse transcriptase polymerase chain reactionTranscriptase polymerase chain reactionDeep learningPredictive of mortalityChest CT imagesClinical featuresValidation cohortMulticentre studyPolymerase chain reactionDense neural networkTest cohortLung damageInternal validitySWEAT ICU—An Observational Study of Physician Workload and the Association of Physician Outcomes in Academic ICUs
Agarwal A, Chen JT, Coopersmith CM, Denson JL, Dickert NW, Ferrante LE, Gershengorn HB, Gosine AD, Hayward BJ, Kaur N, Khan A, Lamberton C, Landsittel D, Lyons PG, Mikkelsen ME, Nadig NR, Pietropaoli AP, Poole BR, Viglianti EM, Sevransky JE, Network O. SWEAT ICU—An Observational Study of Physician Workload and the Association of Physician Outcomes in Academic ICUs. Critical Care Explorations 2022, 4: e0774. PMID: 36259061, PMCID: PMC9575792, DOI: 10.1097/cce.0000000000000774.Peer-Reviewed Original ResearchPatient mortalityICU physiciansObservational studyStudy daysPhysician workloadCross-sectional observational studyMultivariable logistic regression modelAdult ICU patientsSecondary outcome measuresPhysician burnoutNumber of patientsOptimal staffing modelLogistic regression modelsMedian patientICU patientsPrimary outcomeWell-Being IndexPrimary exposurePhysician careOverall prevalencePatient outcomesAcademic ICUsOutcome measuresDay 28Binomial mixed effects models
2020
COVID-19 infections and outcomes in a live registry of heart failure patients across an integrated health care system
Caraballo C, McCullough M, Fuery MA, Chouairi F, Keating C, Ravindra NG, Miller PE, Malinis M, Kashyap N, Hsiao A, Wilson FP, Curtis JP, Grant M, Velazquez EJ, Desai NR, Ahmad T. COVID-19 infections and outcomes in a live registry of heart failure patients across an integrated health care system. PLOS ONE 2020, 15: e0238829. PMID: 32997657, PMCID: PMC7526909, DOI: 10.1371/journal.pone.0238829.Peer-Reviewed Original ResearchConceptsHeart failure patientsIntegrated health care systemHeart Failure RegistryHealth care systemFailure patientsCOVID-19 infectionCare systemCOVID-19SARS-CoV-2 infectionReal-time registryRenin-angiotensin blockersRetrospective chart reviewCoronary artery diseaseRisk of deathCOVID-19 testingAngiotensin blockersMultiple comorbiditiesRespiratory failureChart reviewSymptomatic patientsArtery diseaseHeart failureComorbid conditionsPatient mortalityClinical managementDoes Emergency General Surgery (EGS) Hospital Volume Contribute to Improved Outcomes?
DeWane M, Becher R, Schuster K. Does Emergency General Surgery (EGS) Hospital Volume Contribute to Improved Outcomes? Current Surgery Reports 2020, 8: 17. DOI: 10.1007/s40137-020-00262-6.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsImproved outcomesHospital-based outcomesHigh-volume centersRecent FindingsRecent evidenceEGS volumeHospital mortalitySurgeon volumePatient mortalityVolume centersHigh-risk operationsSurgery volumeReviewThis reviewOutcomesEGS operationsMortalitySpecific factorsPatientsCase complexityObserved improvementDelayed blood transfusion is associated with mortality following radical cystectomy
Tan W, Wang Y, Trinh Q, Preston M, Kelly J, Hrouda D, Kibel A, Krasnow R, Liu J, Chung B, Chang S, Mossanen M. Delayed blood transfusion is associated with mortality following radical cystectomy. Scandinavian Journal Of Urology 2020, 54: 290-296. PMID: 32538224, DOI: 10.1080/21681805.2020.1777195.Peer-Reviewed Original ResearchConceptsDelayed blood transfusionEarly blood transfusionBlood transfusionRadical cystectomyBladder cancer treated with radical cystectomyPatients treated with radical cystectomyAssociated with 90-day mortalityIncreased 90-day mortalityTime of blood transfusionPrimary end pointRetrospective cohort studyMultivariate logistic regressionAssociated with mortalityDelayed transfusionMedian ageClinical deteriorationCystectomyHigher CCIOlder patientsTransfusionCohort studyEnd pointsPatient mortalityPatientsIndex admission
2019
Transfer RNA methyltransferase gene NSUN2 mRNA expression modifies the effect of T cell activation score on patient survival in head and neck squamous carcinoma
Lu L, Gaffney SG, Cannataro VL, Townsend J. Transfer RNA methyltransferase gene NSUN2 mRNA expression modifies the effect of T cell activation score on patient survival in head and neck squamous carcinoma. Oral Oncology 2019, 101: 104554. PMID: 31887619, PMCID: PMC7273869, DOI: 10.1016/j.oraloncology.2019.104554.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBiomarkersFemaleGene Expression Regulation, NeoplasticHumansKaplan-Meier EstimateLymphocyte ActivationMaleMethyltransferasesMiddle AgedNeoplasm GradingNeoplasm StagingPrognosisProportional Hazards ModelsSquamous Cell Carcinoma of Head and NeckT-LymphocytesYoung AdultConceptsT cell activation scoreT cell activation statusAdjusted hazard ratioPatient survivalHPV statusHazard ratioActivation statusActivation scoresKaplan-Meier survival curvesImmune checkpoint blockadeCox regression modelNeck squamous carcinomaPotential therapeutic targetT cell activationHNSCC patientsSquamous carcinomaPatient mortalityLonger survivalExhaustion groupsTherapeutic targetSurvival curvesSignificant associationMRNA expressionPatientsSurvivalTrends in the Incidence of In-Hospital Mortality, Cardiogenic Shock, and Utilization of Mechanical Circulatory Support Devices in Myocarditis (Analysis of National Inpatient Sample Data, 2005–2014)
Pahuja M, Adegbala O, Mishra T, Akintoye E, Chehab O, Mony S, Singh M, Ando T, Abubaker H, Yassin A, Subahi A, Shokr M, Ranka S, Briasoulis A, Kapur N, Burkhoff D, Afonso L. Trends in the Incidence of In-Hospital Mortality, Cardiogenic Shock, and Utilization of Mechanical Circulatory Support Devices in Myocarditis (Analysis of National Inpatient Sample Data, 2005–2014). Journal Of Cardiac Failure 2019, 25: 457-467. PMID: 31035007, DOI: 10.1016/j.cardfail.2019.04.012.Peer-Reviewed Original ResearchConceptsIncidence of CSCardiogenic shockMechanical circulatory supportHospital mortalityMCS devicesPercutaneous ventricular assist deviceNational Inpatient Sample databaseMechanical circulatory support devicesIncidence of myocarditisPercutaneous cardiopulmonary supportCases of myocarditisIn-Hospital MortalityExtracorporeal membrane oxygenationCirculatory support devicesVentricular assist deviceTandem HeartHemodynamic instabilityMultiple comorbiditiesCardiopulmonary supportEndomyocardial biopsyMembrane oxygenationTotal admissionsCirculatory supportPatient mortalityPoor prognosis
2018
Does Dexmedetomidine Ameliorate Postoperative Cognitive Dysfunction? A Brief Review of the Recent Literature
Carr ZJ, Cios TJ, Potter KF, Swick JT. Does Dexmedetomidine Ameliorate Postoperative Cognitive Dysfunction? A Brief Review of the Recent Literature. Current Neurology And Neuroscience Reports 2018, 18: 64. PMID: 30083844, DOI: 10.1007/s11910-018-0873-z.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsUse of dexmedetomidinePostoperative deliriumCognitive dysfunctionAcute postoperative deliriumPostoperative cognitive dysfunctionAlpha-2 agonistsIncidence of POCDAnti-inflammatory propertiesHigh patient mortalityHospital lengthElderly patientsHeart failurePostsurgical patientsPatient mortalityImmunomodulatory effectsVascular diseaseBrain injuryFavorable outcomeClinical studiesDexmedetomidineHigh prevalenceHuman trialsClinical investigationRecent FindingsThereAnimal modelsBariatric Surgery and Hepatocellular Carcinoma: a Propensity Score-Matched Analysis
Njei B, McCarty TR, Sharma P, Lange A, Najafian N, Ngu JN, Ngomba VE, Echouffo-Tcheugui JB. Bariatric Surgery and Hepatocellular Carcinoma: a Propensity Score-Matched Analysis. Obesity Surgery 2018, 28: 3880-3889. PMID: 30069863, PMCID: PMC6219901, DOI: 10.1007/s11695-018-3431-5.Peer-Reviewed Original ResearchConceptsBariatric surgeryHepatocellular carcinomaPrevalence ratiosOdds ratioLow prevalenceUnited States Nationwide Inpatient Sample databaseNationwide Inpatient Sample databaseOccurrence of HCCPropensity scorePrior bariatric surgeryHospital mortality rateMorbidly obese patientsAge-adjusted prevalenceMortality odds ratioRisk of deathLength of stayCross-sectional associationsHospital mortalityMorbid obesityBaseline characteristicsObese patientsSecondary outcomesBackgroundThe associationPrimary outcomePatient mortalityFailure to Rescue, Hospital Volume, and In-Hospital Mortality After Transcatheter Aortic Valve Implantation
Ando T, Adegbala O, Villablanca P, Shokr M, Akintoye E, Briasoulis A, Takagi H, Schreiber T, Grines C, Afonso L. Failure to Rescue, Hospital Volume, and In-Hospital Mortality After Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2018, 122: 828-832. PMID: 30064862, DOI: 10.1016/j.amjcard.2018.05.020.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationMajor perioperative complicationsAortic valve implantationVolume hospitalsHospital volumePatient mortalityPerioperative complicationsValve implantationTransarterial transcatheter aortic valve implantationNationwide Inpatient Sample databaseCo-morbidity indexGreater hospital volumeIn-Hospital MortalityPatient mortality ratesPercentage of womenHospital mortalityMajor complicationsTAVI procedureHighest quintileMean ageLowest quintileAdjusted ratesMortality rateFourth quintileDifferent hospitalsAn investigation of an open‐access model for scaling up methadone maintenance treatment
Madden LM, Farnum SO, Eggert KF, Quanbeck AR, Freeman RM, Ball SA, Schottenfeld RS, Shi JM, Savage ME, Barry DT. An investigation of an open‐access model for scaling up methadone maintenance treatment. Addiction 2018, 113: 1450-1458. PMID: 29453891, DOI: 10.1111/add.14198.Peer-Reviewed Original ResearchConceptsNon-medical opioid useOpioid use disorderMethadone maintenance treatmentOpioid useMaintenance treatmentTreatment accessUse disordersTreatment modelMethadone maintenance treatment centersMaintenance treatment centersDeleterious effectsMethadone treatmentPatient mortalityTreatment optionsTreatment outcomesTreatment centersProspective patientsRate of retentionPatient censusRapid enrollmentAddiction treatmentApparent deleterious effectsTreatmentMortalityProgrammatic outcomes
2017
IMPACT OF HOSPITAL OWNERSHIP ON IN-PATIENT MORTALITY AND COST OF HOSPITALIZATION IN PATIENTS ADMITTED FOR HEART FAILURE: INSIGHT FROM THE NATIONAL INPATIENT SAMPLE (NIS)
Akintoye E, Briasoulis A, Orhurhu V, Ibrahim W, Kumar K, Nas H, Weinberger J. IMPACT OF HOSPITAL OWNERSHIP ON IN-PATIENT MORTALITY AND COST OF HOSPITALIZATION IN PATIENTS ADMITTED FOR HEART FAILURE: INSIGHT FROM THE NATIONAL INPATIENT SAMPLE (NIS). Journal Of The American College Of Cardiology 2017, 69: 770. DOI: 10.1016/s0735-1097(17)34159-1.Peer-Reviewed Original Research
2015
Osteoporosis and Hip Fractures
Olgun D, Gianakos A, Jo J, Galmer L, Lane J. Osteoporosis and Hip Fractures. 2015, 141-158. DOI: 10.1007/978-3-319-19905-4_8.Peer-Reviewed Original ResearchHip fractureFragility fracturesFragility fracture risk factorsOsteoporosis-related fragility fracturesMajor public health concernFracture risk factorsFracture liaison serviceMajority of patientsOsteoporotic fragility fracturesResidual functional impairmentOsteoporotic hip fracturesPublic health concernOsteoporosis managementPatient mortalityRisk factorsPatient outcomesPharmacological strategiesFunctional impairmentLiaison serviceSubsequent fracturesGreater riskHealth concernHealthcare expendituresOsteoporosisBone evaluation
2014
New advances in limb salvage.
Chin JA, Sumpio BE. New advances in limb salvage. Surgical Technology Online 2014, 25: 212-6. PMID: 25433346.Peer-Reviewed Original ResearchCritical limb ischemiaLimb salvageDistal vein patchType of therapyDrug-eluting stentsQuality of lifeEndovascular therapyLimb ischemiaPatient mortalityVein patchPoor outcomeEndovascular interventionTreatment optionsMorbid diseaseVascular surgerySurgical techniqueLimb lossHealthcare costsEpidemiologic problemNew advancesTherapySalvageInterventionFurther research
2013
Head-to-Head Comparison of Disaster Triage Methods in Pediatric, Adult, and Geriatric Patients
Cross KP, Cicero MX. Head-to-Head Comparison of Disaster Triage Methods in Pediatric, Adult, and Geriatric Patients. Annals Of Emergency Medicine 2013, 61: 668-676.e7. PMID: 23465555, DOI: 10.1016/j.annemergmed.2012.12.023.Peer-Reviewed Original ResearchConceptsGlasgow Coma ScaleReceiver operator curveOperator curveTriage methodTrauma victimsNational Trauma Data BankGeriatric trauma victimsTrauma registry patientsTrauma Data BankLength of stayTriage accuracyRegistry patientsHospital dischargeSecondary outcomesComa ScaleTrauma patientsGeriatric patientsPatient mortalityEmergency departmentSubgroup analysisTriage levelLarge cohortTriage strategiesTriage assignmentMost subgroups
2008
Nonventilatory Interventions in the Acute Respiratory Distress Syndrome
Schuster KM, Alouidor R, Barquist ES. Nonventilatory Interventions in the Acute Respiratory Distress Syndrome. Journal Of Intensive Care Medicine 2008, 23: 19-32. PMID: 18230633, DOI: 10.1177/0885066607310166.Peer-Reviewed Original ResearchConceptsAcute respiratory distress syndromeRespiratory distress syndromeAcute lung injuryDistress syndromeLung injuryAcute respiratory distress syndrome/acute lung injuryLong-term patient mortalityProne position ventilationExtracorporeal membrane oxygenationNeuromuscular blocking agentsHypoxic patientsRescue therapyFluid restrictionMembrane oxygenationMechanical ventilationLarge trialsPatient mortalityImproved oxygenationExogenous surfactantBlocking agentSyndromeNitric oxideTherapyPatientsInjury
2007
Generalized convulsive status epilepticus after nontraumatic subarachnoid hemorrhage: the nationwide inpatient sample.
Claassen J, Bateman BT, Willey JZ, Inati S, Hirsch LJ, Mayer SA, Sacco RL, Schumacher HC. Generalized convulsive status epilepticus after nontraumatic subarachnoid hemorrhage: the nationwide inpatient sample. Neurosurgery 2007, 61: 60-4; discussion 64-5. PMID: 17621019, DOI: 10.1227/01.neu.0000279724.05898.e7.Peer-Reviewed Original ResearchConceptsNontraumatic subarachnoid hemorrhageConvulsive status epilepticusNationwide Inpatient SampleSubarachnoid hemorrhageRenal diseaseStatus epilepticusInpatient SampleNonfederal United States hospitalsGeneralized convulsive status epilepticusDatabase of admissionsDuration of hospitalizationMultivariate logistic regressionUnited States hospitalsHospital mortalityHospital stayAdult patientsYounger patientsIndependent predictorsPatient mortalityEmergency departmentPatientsLinear regression analysisState HospitalNeurosurgical proceduresLogistic regression
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply