2024
Creation and Validation of an Automated Registry for Outpatient Parenteral Antibiotics
Canterino J, Malinis M, Liu J, Kashyap N, Brandt C, Justice A. Creation and Validation of an Automated Registry for Outpatient Parenteral Antibiotics. Open Forum Infectious Diseases 2024, 11: ofae004. PMID: 38412514, PMCID: PMC10866572, DOI: 10.1093/ofid/ofae004.Peer-Reviewed Original ResearchElectronic medical recordsOutpatient parenteral antibiotic therapyOutpatient parenteral antibiotic therapy programsMedical recordsObjective dataHospital length of stayOPAT episodesLength of stayDischarge dispositionUnique patientsRegistryParenteral antibiotic therapyInsurance payorOutpatient parenteral antibioticsDeath rateHospital lengthHospital daysAntibiotic therapyParenteral antibioticsInfection syndromeHospitalProgramAntibiotic name
2023
Open-Label Trial of Amikacin Liposome Inhalation Suspension in Mycobacterium abscessus Lung Disease
Siegel S, Griffith D, Philley J, Brown-Elliott B, Brunton A, Sullivan P, Fuss C, Strnad L, Wallace R, Winthrop K. Open-Label Trial of Amikacin Liposome Inhalation Suspension in Mycobacterium abscessus Lung Disease. CHEST Journal 2023, 164: 846-859. PMID: 37419144, PMCID: PMC10645596, DOI: 10.1016/j.chest.2023.05.036.Peer-Reviewed Original ResearchConceptsAmikacin liposome inhalation suspensionAmikacin resistanceCulture conversionInhalation suspensionMycobacterium abscessus lung diseasePresence of macrolide resistanceEnd pointsMicrobiological end pointsMonthly sputum culturesSputum culture conversionTreatment-refractory diseaseOpen-label protocolSecondary end pointsOpen-label trialCohort of patientsCavitary diseaseSputum culturePretreatment isolatesM abscessusOpen-labelOral antimicrobialsParenteral antibioticsCompanion therapyMacrolide resistanceMultidrug therapy
2019
Parenteral Antibiotic Therapy Duration in Young Infants With Bacteremic Urinary Tract Infections
Desai S, Aronson PL, Shabanova V, Neuman MI, Balamuth F, Pruitt CM, DePorre AG, Nigrovic LE, Rooholamini SN, Wang ME, Marble RD, Williams DJ, Sartori L, Leazer RC, Mitchell C, Shah SS. Parenteral Antibiotic Therapy Duration in Young Infants With Bacteremic Urinary Tract Infections. Pediatrics 2019, 144: e20183844. PMID: 31431480, PMCID: PMC6855812, DOI: 10.1542/peds.2018-3844.Peer-Reviewed Original ResearchConceptsBacteremic urinary tract infectionUrinary tract infectionAntibiotic durationParenteral antibioticsTract infectionsFrequent recurrent urinary tract infectionsYoung infantsMulticenter retrospective cohort studyRecurrent urinary tract infectionsAntibiotic therapy durationShort-course groupRetrospective cohort studyLong-course therapyMarginal structural modelsHospital reutilizationUTI recurrenceOral antibioticsCohort studyParenteral therapyPatient characteristicsTherapy durationUrine cultureChildren's HospitalWeighted populationEarly conversion
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