2025
Ultrasound‐Guided Nerve Block for Pediatric Femur Fractures in the Emergency Department: A Prospective Multi‐Center Study
Binder Z, Ng C, Klekowski N, Lawson S, Riera A, Toney A, Pade K, Saint The T, Shaahinfar A, Chaudoin L, Lauer E, Snelling P, Moake M. Ultrasound‐Guided Nerve Block for Pediatric Femur Fractures in the Emergency Department: A Prospective Multi‐Center Study. Academic Emergency Medicine 2025 PMID: 40524602, DOI: 10.1111/acem.70084.Peer-Reviewed Original ResearchPediatric emergency medicineFascia iliaca compartment nerve blockEmergency departmentPediatric femur fracturesFemur fracturesPain intensityPediatric emergency medicine physiciansSelf-reported pain intensityFaces Pain Scale-RevisedFracture pain managementPain scoresChildren aged 4Pain score reductionEmergency medicinePost-enrollmentAdverse eventsNerve blockPain managementSecondary outcomesOpioid medicationsPrimary outcomeOral morphine equivalentsProcedure useUltrasound-guided nerve blockProspective multi-center studyA Novel Electronic Health Record-Integrated Clinical Pathway for Nephrolithiasis: Development and Management Outcomes.
Lokeshwar S, Choksi A, Smani S, Heacock D, Kanaparthy N, Shaheen D, Dashevsky M, Martin T, Singh D, Motamedinia P, Sangal R. A Novel Electronic Health Record-Integrated Clinical Pathway for Nephrolithiasis: Development and Management Outcomes. Urology Practice 2025, 101097upj0000000000000847. PMID: 40459510, DOI: 10.1097/upj.0000000000000847.Peer-Reviewed Original ResearchEmergency departmentRenal colicClinical pathwayPain controlEvidence-based pain managementED patient careInadequate discharge planningAcute renal colicMedical expulsive therapyUrological follow-upMann-Whitney <i>Retrospective cohort studyEnhanced pain controlDischarge planningHealth systemDischarge practicesKetorolac doseOpioid alternativesPatient careExpulsive therapyLidocaine usePathway useOpioid useStandard carePain managementCurrent state of anesthesiology experience with buprenorphine for pain management: results of a nationwide survey
Hopkins R, MacLean R, Pittman B, Missair A, Gaiser R, Perrino A, Hickey T. Current state of anesthesiology experience with buprenorphine for pain management: results of a nationwide survey. Regional Anesthesia & Pain Medicine 2025, rapm-2025-106692. PMID: 40360200, DOI: 10.1136/rapm-2025-106692.Peer-Reviewed Original ResearchLetter to the Editor: Effect of Nicotine Replacement Therapy on Perioperative Pain Management and Opioid Requirement in Abstinent Tobacco Smokers Undergoing Spinal Fusion: A Double-Blind Randomized Controlled Trial.
Costa G, De Aquino J. Letter to the Editor: Effect of Nicotine Replacement Therapy on Perioperative Pain Management and Opioid Requirement in Abstinent Tobacco Smokers Undergoing Spinal Fusion: A Double-Blind Randomized Controlled Trial. Journal Of Neurosurgical Anesthesiology 2025 PMID: 40325556, DOI: 10.1097/ana.0000000000001041.Peer-Reviewed Original ResearchSubstance Use and Chronic Pain Management: Understanding the Learning Needs of Primary Care Clinicians Through Project ECHO
Katzman J, Warrick B, Takeda M, Bhatt S, Grandhe R, Jacobsohn V, Tomedi L. Substance Use and Chronic Pain Management: Understanding the Learning Needs of Primary Care Clinicians Through Project ECHO. Healthcare 2025, 13: 873. PMID: 40281822, PMCID: PMC12027298, DOI: 10.3390/healthcare13080873.Peer-Reviewed Original ResearchPrimary care cliniciansCare cliniciansFocus groupsPatient centered carePatient-centered careInteractive case discussionCase discussionSubstance useSubstance use managementModified Delphi techniqueClinical practice guidelinesChronic pain managementPost-session surveysProject ECHOHub-teamThematic analysisPain managementPractice guidelinesPrescribed opioidsCore themesDelphi techniqueChronic painOpioid overdoseUS regionsCommunication skillsMachine learning predicting acute pain and opioid dose in radiation treated oropharyngeal cancer patients
Salama V, Humbert-Vidan L, Godinich B, Wahid K, ElHabashy D, Naser M, He R, Mohamed A, Sahli A, Hutcheson K, Gunn G, Rosenthal D, Fuller C, Moreno A. Machine learning predicting acute pain and opioid dose in radiation treated oropharyngeal cancer patients. Frontiers In Pain Research 2025, 6: 1567632. PMID: 40256643, PMCID: PMC12006146, DOI: 10.3389/fpain.2025.1567632.Peer-Reviewed Original ResearchMorphine equivalent daily doseBaseline pain scoresPain intensityOpioid doseRadiation therapyAnalgesic efficacyPain scoresAcute painPatients treated with RTOral cavity/oropharyngeal cancerPersonalized pain managementPredicting pain intensityOropharyngeal cancer patientsAcute pain severityEquivalent daily doseEarly risk stratificationVital signsLogistic regressionRisk stratification modelOpioid requirementsPain severityDaily doseRetrospective studyRisk stratificationPain managementCommon Cryoneurolysis Targets in Pain Management: Indications, Critical Anatomy, and Potential Complications
Sailer A, Latich I, Levey A. Common Cryoneurolysis Targets in Pain Management: Indications, Critical Anatomy, and Potential Complications. Seminars In Interventional Radiology 2025, 42: 205-212. PMID: 40376212, PMCID: PMC12077947, DOI: 10.1055/s-0045-1804492.Peer-Reviewed Original ResearchQuality of lifePain managementCombination of therapiesImprove quality of lifeIncreased healthcare costsOpioid consumptionAdjunctive therapyHealthcare costsPatient's painUncontrolled painPhysical sufferingPainPotential complicationsAnatomical considerationsCryoneurolysisAbstract PainImprove qualityPatient outcomesPatientsClinical settingPerson's abilityCritical anatomyPatient pathologyTherapyPersonsComplementary and integrative health approaches used for pain management by U.S. adults with chronic fatigue syndrome/myalgic encephalomyelitis: Findings from the 2022 National Health Interview Survey
Adamowicz J, Sirotiak Z, Thomas E, Lund B, Hadlandsmyth K, Driscoll M. Complementary and integrative health approaches used for pain management by U.S. adults with chronic fatigue syndrome/myalgic encephalomyelitis: Findings from the 2022 National Health Interview Survey. European Journal Of Integrative Medicine 2025, 75: 102443. DOI: 10.1016/j.eujim.2025.102443.Peer-Reviewed Original ResearchIntegrative health approachesHealth approachChronic fatigue syndrome/myalgic encephalomyelitisPain-relatedDepressive symptomsNational Health Interview Survey dataU.S. National Health Interview Survey dataPain managementHealth Interview Survey dataNational Health Interview SurveyIntegrative health modalityRao-Scott chi-square testsHealth Interview SurveyInterview Survey dataChiropractic careHealth modalitiesInterview SurveySurvey weightsChi-square testU.S. adultsRao-ScottExperience painAssociated with usageHealth useCFS/MEAcute Pain Management in People With Opioid Use Disorder : A Systematic Review.
Buonora M, Mackey K, Khalid L, Hickey T, Grimshaw A, Moss M, Starrels J, Alford D, Becker W, Weimer M. Acute Pain Management in People With Opioid Use Disorder : A Systematic Review. Annals Of Internal Medicine 2025, 178: 558-570. PMID: 40096692, DOI: 10.7326/annals-24-01917.Peer-Reviewed Original ResearchConceptsOpioid use disorderOUD outcomesAcute pain interventionsAcute pain managementPain interventionsPain outcomesEmergency departmentPain managementObservational studyUse disorderImprove pain-related outcomesPerioperative settingEffectiveness of pain interventionsPain-related outcomesWell-conducted randomized controlled trialsImprove pain outcomesAcute painful episodesStrength of evidence assessmentIntravenous (IVControlled observational studiesNon-U.S. populationsEffectiveness of interventionsRandomized controlled trialsOral clonidineRisk of biasPsychedelics for Cancer Pain and Associated Psychological Distress: A Narrative Review of a Potential Strategy
Belitzky E, Carvalho L, Taylor M, Ortiz C, Baum L, Fiellin D, Lustberg M. Psychedelics for Cancer Pain and Associated Psychological Distress: A Narrative Review of a Potential Strategy. Cancer Medicine 2025, 14: e70586. PMID: 40052631, PMCID: PMC11886891, DOI: 10.1002/cam4.70586.Peer-Reviewed Original ResearchConceptsManagement of cancer painPsychological distressCancer painSymptom burdenUndertreatment of cancer painLevels of psychological distressFear of recurrenceSymptoms of cancerAssociated symptom burdenImprove pain managementMitigate psychological distressQuality of life challengesCancer-related painMitigate painAssociated psychological distressTreatment of cancer painNon-pharmacological approachesDiagnosis of cancerEfficacy of psychedelicsFear of deathLevel of evidenceCurrent level of evidenceBehavioral counselingCancer populationPain managementKnowledge, Awareness, and Attitudes Regarding Axial Spondylarthritis Among Nonrheumatology Physicians in the United States.
Odell W, Alexander S, Maheshwari N, Danve A. Knowledge, Awareness, and Attitudes Regarding Axial Spondylarthritis Among Nonrheumatology Physicians in the United States. The Journal Of Rheumatology 2025, jrheum.2024-0552. PMID: 40041999, DOI: 10.3899/jrheum.2024-0552.Peer-Reviewed Original ResearchChronic back painInflammatory back painReduce diagnostic delayReferral guidelinesBack painDiagnostic delayPhysical medicine/rehabilitationImaging testsSurveyed physiciansNext imaging testPain managementSuspected axSpAC-reactive proteinFamily/internal medicineUnited StatesAxial spondylarthritisImprove educationPhysiciansReferralAxial spondyloarthritisRisk factorsMagnetic resonance imagingAxSpANonradiographic axSpAOnline questionnairePredictors of Pain Concordance Among Caregiver–Child Dyads Undergoing Elective Surgery
Lim P, Fortier M, Kaplan S, Masague S, Kain Z. Predictors of Pain Concordance Among Caregiver–Child Dyads Undergoing Elective Surgery. Pediatric Anesthesia 2025, 35: 359-366. PMID: 39960137, DOI: 10.1111/pan.15082.Peer-Reviewed Original ResearchCaregiver-child dyadsChildren's painChild Health Ratings InventoriesSelf-report of painChildren's self-reports of painPain ratingsPain severity ratingsChild self-reportProportion of dyadsPostoperative recovery outcomesPain beliefsEffective postoperative pain managementLatinx caregiversPain assessmentCaregiversRecovery outcomesPain managementPostoperative painDistress measuresCaregiver-childPostoperative pain managementRating InventoryRate of postoperative painLatinx childrenPostoperative pain scoresUnderstanding the Pain Experience and Treatment Considerations Along the Spectrum of Peripheral Artery Disease: A Scientific Statement From the American Heart Association
Smolderen K, Ujueta F, Behan D, Vlaeyen J, Jackson E, Peters M, Whipple M, Phillips K, Chung J, Mena-Hurtado C, Research O. Understanding the Pain Experience and Treatment Considerations Along the Spectrum of Peripheral Artery Disease: A Scientific Statement From the American Heart Association. Circulation Cardiovascular Quality And Outcomes 2025, 18: e000135. PMID: 39925269, DOI: 10.1161/hcq.0000000000000135.Peer-Reviewed Original ResearchConceptsPeripheral arterial diseaseArtery diseaseMultimodal pain management strategiesPain experienceAtypical leg painChronic pain syndromesGeneration of painMultimodal pain managementChronic pain experiencePain management strategiesIschemic rest painPhantom limb painAmerican Heart AssociationNeuropathic painLeg painNeuropathic mechanismsPain syndromeOpioid useChronic painRest painPain managementHeart AssociationLimb painClinical subgroupsIntermittent claudicationPain Management in the Older Adults A Narrative Review
Rajput K, Ng J, Zwolinski N, Chow R. Pain Management in the Older Adults A Narrative Review. Clinics In Geriatric Medicine 2025, 41: 131-151. PMID: 39551538, DOI: 10.1016/j.cger.2024.03.011.Peer-Reviewed Original ResearchConceptsPain managementOlder adult populationOlder adult patientsOlder adultsAdult populationMultiple medicationsLife expectancyClinical practiceAdult patientsMedical managementPreexisting comorbiditiesPainUnited StatesDegenerative processPracticeNonagenariansMedicationAdultsComorbiditiesReviewManagementOctogenariansPatientsBuprenorphine versus full agonist opioids for acute postoperative pain management: a systematic review and meta-analysis of randomized controlled trials
Hickey T, Costa G, Oliveira D, Podosek A, Abelleira A, Avila-Quintero V, De Aquino J. Buprenorphine versus full agonist opioids for acute postoperative pain management: a systematic review and meta-analysis of randomized controlled trials. Regional Anesthesia & Pain Medicine 2025, rapm-2024-106014. PMID: 39753290, DOI: 10.1136/rapm-2024-106014.Peer-Reviewed Original ResearchAcute postoperative pain managementPostoperative pain managementAcute postoperative painDuration of analgesiaPain intensityPain managementRandomized controlled trialsRisk of biasAgonist opioidsPostoperative painControlled trialsRescue analgesiaMeta-analysis of randomized controlled trialsMean duration of analgesiaRescue analgesia useLong duration of actionCochrane Central Register of Controlled TrialsSafety of buprenorphineCentral Register of Controlled TrialsMeta-analysisRegister of Controlled TrialsRandom-effects meta-analysisAdverse effectsDuration of actionCochrane Central RegisterChapter 20 Postoperative pain management for cesarean delivery
Fiol A, McGuire P, Fardelmann K, Alian A. Chapter 20 Postoperative pain management for cesarean delivery. 2025, 213-221. DOI: 10.1016/b978-0-443-21707-4.00020-3.Peer-Reviewed Original Research
2024
Perioperative Pain Management: An Update on Pharmacology with a Special Focus on the Opioid Tolerant Elderly
Chow R, Rajput K. Perioperative Pain Management: An Update on Pharmacology with a Special Focus on the Opioid Tolerant Elderly. Current Anesthesiology Reports 2024, 15: 6. DOI: 10.1007/s40140-024-00656-7.Peer-Reviewed Original ResearchElderly patientsOpioid toleranceChronic painPain managementModerate to high-risk patientsIncreasing use of opioidsOpioid-tolerant patientsSide effects of sedationOpioid sparing effectDoses of opioidsHigh-risk patientsUse of opioidsDrug-drug interactionsChronic opioidsOpioid requirementsTolerant patientsMultimodal analgesicsEffects of sedationPerioperative painRespiratory depressionHome dosePreexisting comorbiditiesPain surgeryRegional anestheticsPerioperative periodPain can’t be carved at the joints: defining function-based pain profiles and their relevance to chronic disease management in healthcare delivery design
Barron D, Saltoun K, Kiesow H, Fu M, Cohen-Tanugi J, Geha P, Scheinost D, Isaac Z, Silbersweig D, Bzdok D. Pain can’t be carved at the joints: defining function-based pain profiles and their relevance to chronic disease management in healthcare delivery design. BMC Medicine 2024, 22: 594. PMID: 39696368, PMCID: PMC11656997, DOI: 10.1186/s12916-024-03807-z.Peer-Reviewed Original ResearchConceptsChronic diseasesPain ProfileChronic conditionsPatient functionPain conditionsManagement of chronic diseasesChronic disease managementContinuum of careHealthcare delivery systemImprove quality of lifeQuality of lifePainful body partPain interferenceAssociated with clinical variablesUK BiobankWhole-body perspectiveHealth strategiesTreatment of individual patientsPain intensityClinically relevant differencesPatient wellbeingPain managementTreat painful conditionsICD codesMedical specialtiesTranscutaneous Auricular Vagus Nerve Stimulation for Managing Pain: A Scoping Review
Chen J, Kuang H, Chen A, Dungan J, Cousin L, Cong X, Patel P, Starkweather A. Transcutaneous Auricular Vagus Nerve Stimulation for Managing Pain: A Scoping Review. Pain Management Nursing 2024, 26: 33-39. PMID: 39690039, DOI: 10.1016/j.pmn.2024.11.006.Peer-Reviewed Original ResearchConceptsScoping reviewTranscutaneous auricular vagus nerve stimulationChronic low back painPain managementEvaluate intervention fidelityLow back painAuricular vagus nerve stimulationPain conditionsPreferred Reporting ItemsPeer-reviewed journalsTranscutaneous nerve stimulationIntervention fidelityHealthcare professionalsBack painManaging painNerve stimulationSociodemographic variablesReporting ItemsInclusion of measuresVagus nerve stimulationEfficacy of transcutaneous auricular vagus nerve stimulationSystematic reviewSystematic searchMeSH termsLiterature searchPractice Advisory for Postoperative Pain Management of Thoracic Surgical Patients: A Report from the Society of Cardiovascular Anesthesiologists
Makkad B, Heinke T, Sheriffdeen R, Meng M, Kachulis B, Grant M, Popescu W, Brodt J, Khatib D, Wu C, Kertai M, Bollen B. Practice Advisory for Postoperative Pain Management of Thoracic Surgical Patients: A Report from the Society of Cardiovascular Anesthesiologists. Journal Of Cardiothoracic And Vascular Anesthesia 2024, 39: 1306-1324. PMID: 39890582, DOI: 10.1053/j.jvca.2024.12.004.Peer-Reviewed Original ResearchPostoperative pain managementThoracic surgeryPain managementRisk of postoperative respiratory complicationsPersistent post-thoracotomy painPost-thoracotomy painThoracic surgical patientsPostoperative respiratory complicationsAcute pain managementClearance of secretionsPain management decisionsSociety of Cardiovascular AnesthesiologistsNon-pharmacological therapiesOpioid useAcute painMultimodal analgesiaRespiratory complicationsPharmacological therapySurgical patientsNormal respiratory mechanicsQuality of lifeOpioidSurgeryPainRespiratory mechanics
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