2025
Computational Nuclear Oncology Toward Precision Radiopharmaceutical Therapies: Current Tools, Techniques, and Uncharted Territories.
Yusufaly T, Roncali E, Brosch-Lenz J, Uribe C, Jha A, Currie G, Dutta J, El-Fakhri G, McMeekin H, Pandit-Taskar N, Schwartz J, Shi K, Strigari L, Zaidi H, Saboury B, Rahmim A. Computational Nuclear Oncology Toward Precision Radiopharmaceutical Therapies: Current Tools, Techniques, and Uncharted Territories. Journal Of Nuclear Medicine 2025, jnumed.124.267927. PMID: 39947910, DOI: 10.2967/jnumed.124.267927.Peer-Reviewed Original ResearchRadiopharmaceutical therapyImage-based dosimetryPrediction of doseInternal dosimetryPersonalized treatment plansMetastatic diseaseDosimetryNuclear oncologyClinical outcomesNuclear medicineClinical endpointsTreatment planningOncology communityDose responseEtiological mechanismsTargeted deliveryRadiobiologyRadiotherapyMalignancyRadiationLong-termTherapyPharmacotherapyDoseRadiopharmacokineticsComputational Nuclear Oncology Toward Precision Radiopharmaceutical Therapies: Ethical, Regulatory, and Socioeconomic Dimensions of Theranostic Digital Twins
Strigari L, Schwarz J, Bradshaw T, Brosch-Lenz J, Currie G, El-Fakhri G, Jha A, Mežinska S, Pandit-Taskar N, Roncali E, Shi K, Uribe C, Yusufaly T, Zaidi H, Rahmim A, Saboury B. Computational Nuclear Oncology Toward Precision Radiopharmaceutical Therapies: Ethical, Regulatory, and Socioeconomic Dimensions of Theranostic Digital Twins. Journal Of Nuclear Medicine 2025, jnumed.124.268186. PMID: 39848769, DOI: 10.2967/jnumed.124.268186.Peer-Reviewed Original ResearchRadiopharmaceutical therapyNuclear oncologySociety of Nuclear MedicinePredictive dosimetryDosimetric informationTreatment planningTreatment outcomesLack of reimbursementTreatment personalizationDose responseTreatment optimizationEtiological mechanismsRobust security measuresPatient consentReal-world systemsNuclear medicineCross-border data sharingPatientsTreatmentEthical approval
2022
Joint EANM/SIOPE/RAPNO practice guidelines/SNMMI procedure standards for imaging of paediatric gliomas using PET with radiolabelled amino acids and [18F]FDG: version 1.0
Piccardo A, Albert N, Borgwardt L, Fahey F, Hargrave D, Galldiks N, Jehanno N, Kurch L, Law I, Lim R, Lopci E, Marner L, Morana G, Young Poussaint T, Seghers V, Shulkin B, Warren K, Traub-Weidinger T, Zucchetta P. Joint EANM/SIOPE/RAPNO practice guidelines/SNMMI procedure standards for imaging of paediatric gliomas using PET with radiolabelled amino acids and [18F]FDG: version 1.0. European Journal Of Nuclear Medicine And Molecular Imaging 2022, 49: 3852-3869. PMID: 35536420, PMCID: PMC9399211, DOI: 10.1007/s00259-022-05817-6.Peer-Reviewed Original ResearchConceptsAmino acid positron emission tomographyPositron emission tomographyPaediatric neuro-oncologyEuropean Society for Paediatric Oncology (SIOPENeuro-oncologyLevel of evidenceBrain tumor groupPositron emission tomography imagingEvidence-based recommendationsPaediatric patientsTumor groupResponse assessmentClinician guidelinesPaediatric gliomasBrain gliomasImaging specialistsEmission tomographyRadiolabeled amino acidsConsensus opinionEANMPaediatric oncologyPET radiopharmaceuticalsGliomaNuclear medicineOncologySNMMI procedure standard/EANM practice guideline on pediatric [99mTc]Tc-DMSA renal cortical scintigraphy: an update
Vali R, Armstrong I, Bar-Sever Z, Biassoni L, Borgwardt L, Brown J, Grant F, Mandell G, Majd M, Nadel H, Ng T, Roca-Bielsa I, Rohringer T, Santos A, Seghers V, Shaikh N, Ted Treves S, Zaffino-Nevrotski T, Zucchetta P, Lim R. SNMMI procedure standard/EANM practice guideline on pediatric [99mTc]Tc-DMSA renal cortical scintigraphy: an update. Clinical And Translational Imaging 2022, 10: 173-184. DOI: 10.1007/s40336-022-00484-x.Peer-Reviewed Original ResearchEuropean Association of Nuclear MedicineRenal cortical scintigraphyCortical scintigraphyStandard of careImprove patient careEvidence-based recommendationsProfessional medical associationsLevel of trainingLevel of evidenceMedicine careTechnology subsequent to publicationPatient careLegal standard of careMedicine physiciansNuclear medicineMedicine practicePractice guidelinesDiagnostic nuclear medicine imagingCareComplexity of human conditionsExpert consensusMedical professionalsNuclear medicine physiciansPractice medicineMedical Association
2021
Management of Pediatric Graves Disease
Quintanilla-Dieck L, Khalatbari HK, Dinauer CA, Rastatter JC, Chelius DC, Katowitz WR, Shindo ML, Parisi MT, Kazahaya K. Management of Pediatric Graves Disease. JAMA Otolaryngology - Head & Neck Surgery 2021, 147: 1110-1118. PMID: 34647991, DOI: 10.1001/jamaoto.2021.2715.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsGraves' diseaseClinical presenting signsPediatric Graves' diseaseSustained remission rateRadioactive iodine therapyFirst-line treatmentSpecific clinical characteristicsMultidisciplinary approachIodine therapyRemission rateClinical characteristicsDefinitive treatmentMedical therapyPediatric patientsPresenting signMedical managementPediatric populationAntithyroid drugsTherapeutic optionsCertain patientsTreatment optionsOptimal treatmentThyroid ultrasonographyPediatric expertsNuclear medicineImaging of Pulmonary Hypertension in Adults: A Position Paper from the Fleischner Society
Remy-Jardin M, Ryerson C, Schiebler M, Leung A, Wild J, Hoeper M, Alderson P, Goodman L, Mayo J, Haramati L, Ohno Y, Thistlethwaite P, van Beek E, Knight S, Lynch D, Rubin G, Humbert M. Imaging of Pulmonary Hypertension in Adults: A Position Paper from the Fleischner Society. Radiology 2021, 298: 203108. PMID: 33399507, DOI: 10.1148/radiol.2020203108.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPulmonary hypertensionSystematic reviewCause of PHComplications of PHEvaluation of PHManagement of PHMean pulmonary artery pressureChronic thromboembolic pulmonary hypertensionTreatment of PHPulmonary artery pressureThromboembolic pulmonary hypertensionManagement of patientsSimilar pathophysiologic mechanismsUtility of CTSimultaneous joint publicationArtery pressurePathophysiologic mechanismsTherapeutic managementMultidisciplinary assessmentHemodynamic characteristicsFleischner SocietyWorking GroupTreatment planningKey roleNuclear medicine
2020
SNMMI Procedure Standard/EANM Practice Guideline on Pediatric 18F-FDG PET/CT for Oncology 1.0
Vali R, Alessio A, Balza R, Borgwardt L, Bar-Sever Z, Czachowski M, Jehanno N, Kurch L, Pandit-Taskar N, Parisi M, Piccardo A, Seghers V, Shulkin B, Zucchetta P, Lim R. SNMMI Procedure Standard/EANM Practice Guideline on Pediatric 18F-FDG PET/CT for Oncology 1.0. Journal Of Nuclear Medicine 2020, 62: 99-110. PMID: 33334912, PMCID: PMC8679588, DOI: 10.2967/jnumed.120.254110.Peer-Reviewed Original ResearchConceptsEuropean Association of Nuclear MedicineF-FDG PET/CTF-FDGComputerized tomographyTechnology subsequent to publicationEvidence-based recommendationsLevel of trainingNuclear medicineLevel of evidenceDiagnostic nuclear medicine imagingPractice of medicineComplexity of human conditionsMedicine careStandard of careScience of nuclear medicineLegal standard of careCourse of actionMedicine practiceConsensus processPractice guidelinesSociety of Nuclear MedicinePediatric oncologyMedical professionalsClinician guidelinesApplications of nuclear medicine
2019
Diagnostic Reference Levels for Adult Nuclear Medicine Imaging Established from the National Survey in Korea
Song H, Na M, Kim J, Cho S, Park J, Kang K. Diagnostic Reference Levels for Adult Nuclear Medicine Imaging Established from the National Survey in Korea. Nuclear Medicine And Molecular Imaging 2019, 53: 64-70. PMID: 30828403, PMCID: PMC6377576, DOI: 10.1007/s13139-019-00585-y.Peer-Reviewed Original ResearchNuclear medicine imagingOptimizing radiation protectionDiagnostic reference levelsField of nuclear medicine imagingKorean Society of Nuclear MedicineMedicine imagingNuclear medicine imaging studiesRadiation protectionImaging studiesAdministered activityDiagnostic reference level valuesNuclear medicineKorean adultsMyocardial perfusion imagingSociety of Nuclear MedicinePreliminary diagnostic references levelsPreliminary DRL valuesPerfusion imaging
2017
A joint procedural position statement on imaging in cardiac sarcoidosis: from the Cardiovascular and Inflammation & Infection Committees of the European Association of Nuclear Medicine, the European Association of Cardiovascular Imaging, and the American Society of Nuclear Cardiology
Slart R, Glaudemans A, Lancellotti P, Hyafil F, Blankstein R, Schwartz R, Jaber W, Russell R, Gimelli A, Rouzet F, Hacker M, Gheysens O, Plein S, Miller E, Dorbala S, Donal E, Sciagra R, Bucerius J, Verberne H, Lindner O, Übleis C, Agostini D, Signore A, Edvardsen T, Neglia D, Beanlands R, Di Carli M, Chareonthaitawee P, Dilsizian V, Soman P, Habib G, Delgado V, Cardim N, Cosyns B, Flachskampf F, Gerber B, Haugaa K, Lombardi M, Masci P. A joint procedural position statement on imaging in cardiac sarcoidosis: from the Cardiovascular and Inflammation & Infection Committees of the European Association of Nuclear Medicine, the European Association of Cardiovascular Imaging, and the American Society of Nuclear Cardiology. European Heart Journal - Cardiovascular Imaging 2017, 18: 1073-1089. PMID: 28984894, DOI: 10.1093/ehjci/jex146.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsCardiac Imaging TechniquesCardiologyCardiomyopathiesEuropeFemaleHumansMagnetic Resonance ImagingMaleMultimodal ImagingMyocardial Perfusion ImagingNuclear MedicinePositron Emission Tomography Computed TomographyPractice Guidelines as TopicRadionuclide ImagingSarcoidosisSocieties, MedicalUnited StatesConceptsCardiac sarcoidosisEuropean AssociationManagement of patientsCardiovascular magnetic resonanceMyocardial perfusion imagingPositron emission tomographyJoint position paperInfection committeeMulti-center dataClinical trialsSarcoidosisPerfusion imagingEmission tomographyCardiovascular imagingPosition statementAmerican SocietyNuclear cardiologyPosition paperNuclear medicineMagnetic resonanceAssociationCorrect useImagingEchocardiographyInflammation
2016
Up-to-date review of nuclear medicine applications in pediatric thoracic imaging
Kwatra N, Grant F, Lim R, Lee E. Up-to-date review of nuclear medicine applications in pediatric thoracic imaging. European Journal Of Radiology 2016, 95: 418-427. PMID: 27142495, DOI: 10.1016/j.ejrad.2016.04.007.Peer-Reviewed Original ResearchRadiation Safety in Nuclear Medicine Procedures
Cho S, Kim J, Song H. Radiation Safety in Nuclear Medicine Procedures. Nuclear Medicine And Molecular Imaging 2016, 51: 11-16. PMID: 28250853, PMCID: PMC5313457, DOI: 10.1007/s13139-016-0406-0.Peer-Reviewed Original Research
2014
Physical Aspects of Pediatric Nuclear Medicine Imaging
Fahey F, Lim R, El-Fakhri G. Physical Aspects of Pediatric Nuclear Medicine Imaging. 2014, 621-643. DOI: 10.1007/978-1-4614-9551-2_27.Peer-Reviewed Original ResearchNuclear medicine imagingReduction of radiation doseMedicine imagingQuality of nuclear medicine imagingNuclear medicine studiesApplications of nuclear medicineClinical resultsRadiation doseImage quality improvementTomographic reconstructionHybrid imagingMedicine studiesPatientsNuclear medicineChildrenReconstruction technique
2005
Collimator Optimization for Detection and Quantitation Tasks: Application to Gallium-67 Imaging
Moore S, Kijewski M, Fakhri G. Collimator Optimization for Detection and Quantitation Tasks: Application to Gallium-67 Imaging. IEEE Transactions On Medical Imaging 2005, 24: 1347-1356. PMID: 16229420, DOI: 10.1109/tmi.2005.857211.Peer-Reviewed Original ResearchMeSH KeywordsCitratesComputer SimulationComputer-Aided DesignEquipment DesignEquipment Failure AnalysisGalliumHumansImage EnhancementImage Interpretation, Computer-AssistedModels, BiologicalNeoplasmsPhantoms, ImagingPositron-Emission TomographyRadiopharmaceuticalsReproducibility of ResultsSensitivity and SpecificityConceptsMedium-energy low-penetration collimatorCollimator optimizationGeometric spatial resolutionPhotopeak energy windowSimulation of photon transportLead X-raysClinical imaging tasksActivity estimation taskSignal-to-noise ratioGallium-67 imagingContaminating photonsEnergy windowGeometric efficiencyCollimator designFixed energyPhoton transportOptimal collimatorCollimatorHotelling observerFWHMSpatial resolutionNuclear medicineDetectorResolution valuesImaging tasks
2002
Optimal Parallel-Hole Collimation for Lesion Detection and Activity Estimation in Ga-67 Imaging
Moore S, Kijewski M, Fakhri G. Optimal Parallel-Hole Collimation for Lesion Detection and Activity Estimation in Ga-67 Imaging. 2002, 3: 1390-1392. DOI: 10.1109/nssmic.2002.1239580.Peer-Reviewed Original ResearchCollimator designMedium-energy (MESimulation of photon transportSignal-to-noise ratioParallel-hole collimatorDesign of collimatorsClinical imaging tasksGa-67Contaminating photonsField of nuclear medicineEnergy windowFixed energyPhoton transportOptimal collimatorCollimatorCommercial collimatorsStaging of lymphoma patientsHotelling observerGa-67 imagingNuclear medicine clinicsLesion detectionNuclear medicineDetectorActivity concentrationsResolution values
1989
Modern imaging of the liver: Applications of computerized tomography, ultrasound, nuclear medicine, and magnet resonance imaging Edited by M. A. Wilson and F. F. Ruzicka. 712 pp., $150.00 (U.S. and Canada), $180.00 (all other countries). Marcel Dekker, Inc., New York, 1989
Glickman M. Modern imaging of the liver: Applications of computerized tomography, ultrasound, nuclear medicine, and magnet resonance imaging Edited by M. A. Wilson and F. F. Ruzicka. 712 pp., $150.00 (U.S. and Canada), $180.00 (all other countries). Marcel Dekker, Inc., New York, 1989. Gastroenterology 1989, 97: 1347-1348. DOI: 10.1016/0016-5085(89)91719-8.Commentaries, Editorials and Letters
1988
Correlative imaging in abdominal infection: An algorithmic approach using nuclear medicine, ultrasound, and computed tomography
Gagliardi P, Hoffer P, Rosenfield A. Correlative imaging in abdominal infection: An algorithmic approach using nuclear medicine, ultrasound, and computed tomography. Seminars In Nuclear Medicine 1988, 18: 320-334. PMID: 3062784, DOI: 10.1016/s0001-2998(88)80041-2.Peer-Reviewed Original ResearchConceptsAbdominal infectionAbdominal abscessComplicated abdominal infectionGallium-67 scintigraphyPelvic inflammatory diseaseMultiple imaging studiesPlain film radiographyLimited diagnostic valueWBC scintigraphySignificant morbidityAbscess detectionClinical presentationSophisticated imaging techniquesClinical evaluationInflammatory diseasesAnatomic sitesInfectious processNuclear medicineUnnecessary examinationsDisease processImaging techniquesClinical diagnosisDiagnostic valueDifferent imaging techniquesImaging studies
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