2024
Reactive axillary lymph nodes after COVID-19 mRNA vaccination: comparison of mRNA vs. attenuated whole-virus vaccines
Adin M, Isufi E, Wu J, Pang Y, Nguyen D, Has D, Caner C, Aboueldaha N, Mossa-Basha M, Pucar D. Reactive axillary lymph nodes after COVID-19 mRNA vaccination: comparison of mRNA vs. attenuated whole-virus vaccines. Nuclear Medicine Communications 2024, 45: 474-480. PMID: 38465449, DOI: 10.1097/mnm.0000000000001833.Peer-Reviewed Original ResearchAxillary lymph nodesWhole virus vaccineLymph nodesMRNA vaccinesNatural courseValue of clinical parametersCOVID-19 mRNA vaccinesPredictive value of clinical parametersDose of vaccine administrationPET-CT studiesCohort of oncology patientsDeauville criteriaPET criteriaClinical parametersYounger patientsSingle doseModerna recipientsJ&J vaccinePET-positiveMultivariate analysisVaccine typesOncology patientsPredictive valueVaccine administrationModerna vaccine
2022
Stability in BMI over time is associated with a better cognitive trajectory in older adults
Beeri M, Tirosh A, Lin H, Golan S, Boccara E, Sano M, Zhu C. Stability in BMI over time is associated with a better cognitive trajectory in older adults. Alzheimer's & Dementia 2022, 18: 2131-2139. PMID: 35049119, PMCID: PMC9296696, DOI: 10.1002/alz.12525.Peer-Reviewed Original ResearchConceptsBody mass indexBMI changeCognitive trajectoriesAlzheimer's Disease CenterFollow-up body mass indexCognitive declineOlder adultsFollow-up visitHealth phenomenaMass indexNon-dementedDisease CenterLongitudinal dataBaselineOverweightNatural courseClinical valueHealthVisitsParticipantsAdultsDeclineStandard deviation
2021
Prevention of host-to-host transmission by SARS-CoV-2 vaccines
Mostaghimi D, Valdez CN, Larson HT, Kalinich CC, Iwasaki A. Prevention of host-to-host transmission by SARS-CoV-2 vaccines. The Lancet Infectious Diseases 2021, 22: e52-e58. PMID: 34534512, PMCID: PMC8439617, DOI: 10.1016/s1473-3099(21)00472-2.Peer-Reviewed Original ResearchConceptsSARS-CoV-2SARS-CoV-2 vaccinesSymptomatic COVID-19Population-level dataVaccine's abilityIntramuscular vaccineImmunological mechanismsVaccine strategiesVaccine capacityPrimary infectionNatural courseClinical trialsObservational studyRespiratory epitheliumReal-world settingViral titresViral replicationVaccineVaccine distributionInfectionCOVID-19Host transmissionTrialsPopulation-level effectsMucosaTreatment of Acute Pancreatitis in The Emergency Room
Muniraj T, Vege S. Treatment of Acute Pancreatitis in The Emergency Room. 2021, 53-58. DOI: 10.1002/9781119570097.ch7.Peer-Reviewed Original ResearchHours of presentationAcute pancreatitisEmergency roomFluid resuscitationEarly aggressive fluid resuscitationUrgent endoscopic retrograde cholangiopancreatographyCommon gastrointestinal causesPrompt accurate diagnosisAggressive fluid resuscitationAcute abdominal painCornerstone of managementEndoscopic retrograde cholangiopancreatographyGastrointestinal causesAbdominal painProphylactic antibioticsHospital admissionRetrograde cholangiopancreatographySpecialist consultationCommon complaintEarly managementNatural coursePossible etiologiesPatient outcomesBetter outcomesFatal disease
2018
Chronic kidney disease, worsening renal function and outcomes in a heart failure community setting: A UK national study
Lawson CA, Testani JM, Mamas M, Damman K, Jones PW, Teece L, Kadam UT. Chronic kidney disease, worsening renal function and outcomes in a heart failure community setting: A UK national study. International Journal Of Cardiology 2018, 267: 120-127. PMID: 29957251, PMCID: PMC6024224, DOI: 10.1016/j.ijcard.2018.04.090.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseRenal functionKidney diseasePrevalence of CKDModerate chronic kidney diseaseSevere chronic kidney diseasePresence of diabetesAdjusted risk estimatesGlomerular filtration rateCase-control studyHeart failure monitoringUK national studyHF prognosisFirst hospitalisationHF patientsRenal declineHF cohortRelated comorbiditiesHF settingFiltration rateNatural courseHospitalisationHigh riskRisk associationCommunity populationAccessory liver within the thoracic cavity
Adin M, Çetinçakmak M, Deniz M, Göya C. Accessory liver within the thoracic cavity. Surgical And Radiologic Anatomy 2018, 40: 1085-1091. PMID: 29860552, DOI: 10.1007/s00276-018-2046-9.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSurgical interventionAccessory liverThoracic cavityLiver tissueOptimal diagnostic modalityNon-operative managementUnnecessary surgical interventionImaging modalitiesAccessible imaging modalityColor Doppler imagingDiagnostic imaging modalitiesUnnecessary radiation exposureType IEctopic liverPresent studyCase reportCommon subtypeThoracic surgeryClinical managementNatural courseDifferential diagnosisDiagnostic modalitiesPostmortem examinationDoppler imagingBiopsy procedure
2017
Untreated oral cavity cancer: Long‐term survival and factors associated with treatment refusal
Cheraghlou S, Kuo P, Mehra S, Yarbrough WG, Judson BL. Untreated oral cavity cancer: Long‐term survival and factors associated with treatment refusal. The Laryngoscope 2017, 128: 664-669. PMID: 28865100, DOI: 10.1002/lary.26809.Peer-Reviewed Original ResearchConceptsOral cavity cancerNatural courseTreatment refusalUnivariate Kaplan-Meier analysisFive-year survival rateFacility case volumeNational Cancer DatabaseStage 4 patientsExtent of diseaseMultivariate Cox regressionEarly-stage patientsKaplan-Meier analysisNumber of patientsCommon malignant diseaseLong-term survivalInitial treatment planningAdvanced diseaseUntreated patientsAdult patientsRetrospective reviewCox regressionPatient's likelihoodPoor prognosisInsurance statusMalignant disease
2016
Should Patients Be Counseled About Possible Recurrence of Perimesencephalic Subarachnoid Hemorrhage?
Malhotra A, Wu X, Borse R, Matouk CC, Bulsara K. Should Patients Be Counseled About Possible Recurrence of Perimesencephalic Subarachnoid Hemorrhage? World Neurosurgery 2016, 94: 580.e17-580.e22. PMID: 27521726, DOI: 10.1016/j.wneu.2016.07.112.Peer-Reviewed Original ResearchConceptsPerimesencephalic subarachnoid hemorrhageAneurysmal subarachnoid hemorrhageSubarachnoid hemorrhageTomography angiographyBetter outcomesBenign natural courseNew neurologic signsComputed tomography angiographyHistory of traumaPossibility of recurrenceDigital subtraction angiographyRecurrent hemorrhageSevere headacheVascular anomaliesNeurologic signsCase reportNatural courseInitial episodeSixth decadeSubarachnoid bleedSudden onsetPossible recurrenceLower riskPatientsPrevious episodesPutamen volume and its clinical and neurological correlates in primary HIV infection
Wright PW, Pyakurel A, Vaida FF, Price RW, Lee E, Peterson J, Fuchs D, Zetterberg H, Robertson KR, Walter R, Meyerhoff DJ, Spudich SS, Ances BM. Putamen volume and its clinical and neurological correlates in primary HIV infection. AIDS 2016, 30: 1789-1794. PMID: 27045376, PMCID: PMC4925211, DOI: 10.1097/qad.0000000000001103.Peer-Reviewed Original ResearchConceptsEarly HIV infectionHIV infectionPutamen volumeCerebrospinal fluidCD4/CD8 ratioCentral nervous system changesCross-sectional neuroimaging studiesTrajectory of HIVCD4 cell countPrimary HIV infectionCortical white matterTotal gray matterNervous system changesEarly HIVFreeSurfer 5.1CD8 ratioT1 MRI scansNeuropsychometric testsNatural coursePHI groupCorpus callosumInterventional strategiesInfection durationNeuropsychological testingVolumetric alterationsResearch Review: Changes in the prevalence and symptom severity of child post‐traumatic stress disorder in the year following trauma – a meta‐analytic study
Hiller R, Meiser‐Stedman R, Fearon P, Lobo S, McKinnon A, Fraser A, Halligan S. Research Review: Changes in the prevalence and symptom severity of child post‐traumatic stress disorder in the year following trauma – a meta‐analytic study. Journal Of Child Psychology And Psychiatry 2016, 57: 884-898. PMID: 27169987, PMCID: PMC4982080, DOI: 10.1111/jcpp.12566.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderMonths posttraumaAdolescent posttraumatic stress disorderSymptom severityPTSD prevalencePrevalence of PTSDStress disorderChild post-traumatic stress disorderPost-traumatic stress disorderProportion of boysTreatment trialsNatural courseAbsence of interventionPTSD screeningPrevalence reductionModerate declinePrevalence estimatesEarly interventionPeer-reviewed studiesSystematic reviewPosttrauma periodSymptom changePTSD diagnosisLongitudinal changesPosttrauma
2014
Progressive increase in central nervous system immune activation in untreated primary HIV-1 infection
Suh J, Sinclair E, Peterson J, Lee E, Kyriakides TC, Li FY, Hagberg L, Fuchs D, Price RW, Gisslen M, Spudich S. Progressive increase in central nervous system immune activation in untreated primary HIV-1 infection. Journal Of Neuroinflammation 2014, 11: 199. PMID: 25465205, PMCID: PMC4263211, DOI: 10.1186/s12974-014-0199-y.Peer-Reviewed Original ResearchConceptsPrimary HIV-1 infectionHIV-1 infectionCSF neopterinCerebrospinal fluidT cellsHIV infectionCentral nervous system immune activationUntreated primary HIV-1 infectionBaseline levelsEarly HIV-1 infectionCSF neopterin concentrationsNervous system inflammationMixed effects modelsCluster of differentiationMajority of subjectsCNS inflammationSystem inflammationAverage followNeopterin concentrationsHIV transmissionImmune activationLumbar punctureResultsA totalIntrathecal inflammationNatural courseEffectiveness of Providence nighttime bracing in patients with adolescent idiopathic scoliosis.
Bohl DD, Telles CJ, Golinvaux NS, Basques BA, DeLuca PA, Grauer JN. Effectiveness of Providence nighttime bracing in patients with adolescent idiopathic scoliosis. Orthopedics 2014, 37: e1085-90. PMID: 25437083, DOI: 10.3928/01477447-20141124-56.Peer-Reviewed Original ResearchConceptsSRS criteriaProvidence braceFusion surgeryRate of progressionNatural history studiesAdolescent idiopathic scoliosisHigh rateOnly part timeSurgical fusionNatural courseBracing protocolInclusion criteriaIdiopathic scoliosisPatientsProgressionAdditional studiesSurgeryHistory studiesScoliosis bracesBraceLimited literatureSecond studySuch bracesPart timeRelative effectivenessFood Allergy Epidemiology and Natural History
Savage J, Johns C. Food Allergy Epidemiology and Natural History. Immunology And Allergy Clinics Of North America 2014, 35: 45-59. PMID: 25459576, PMCID: PMC4254585, DOI: 10.1016/j.iac.2014.09.004.Peer-Reviewed Original ResearchFeasibility of a Newborn Screening and Follow-up Programme for Sickle Cell Disease among South Gujarat (India) Tribal Populations
Italia Y, Krishnamurti L, Mehta V, Raicha B, Italia K, Mehta P, Ghosh K, Colah R. Feasibility of a Newborn Screening and Follow-up Programme for Sickle Cell Disease among South Gujarat (India) Tribal Populations. Journal Of Medical Screening 2014, 22: 1-7. PMID: 25341880, DOI: 10.1177/0969141314557372.Peer-Reviewed Original ResearchConceptsSickle cell diseaseSCD babiesCell diseaseNewborn screeningSevere clinical complicationsHigh fetal hemoglobinNewborn screening programsSickle cell disordersClinical presentationTribal populationClinical complicationsNatural courseScreening programNewborn babiesCell disordersXmn I polymorphismBabiesDiseaseHome careFetal hemoglobinHigh-performance liquid chromatographyRegular monitoringScreeningPopulationΑ-thalassaemiaChanges in Implementation of Two Evidence‐Based Psychotherapies for PTSD in VA Residential Treatment Programs: A National Investigation
Cook JM, Dinnen S, Thompson R, Simiola V, Schnurr PP. Changes in Implementation of Two Evidence‐Based Psychotherapies for PTSD in VA Residential Treatment Programs: A National Investigation. Journal Of Traumatic Stress 2014, 27: 137-143. PMID: 24668757, PMCID: PMC4036220, DOI: 10.1002/jts.21902.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCognitive Behavioral TherapyEducation, ContinuingEvidence-Based PracticeHealth Care SurveysHealth PersonnelHumansImplosive TherapyInterviews as TopicLength of StayMaleMiddle AgedOutcome and Process Assessment, Health CareQualitative ResearchResidential TreatmentStress Disorders, Post-TraumaticUnited StatesUnited States Department of Veterans AffairsVeteransConceptsEvidence-based treatmentsCognitive processing therapyPosttraumatic stress disorderResidential treatment programTreatment programImplementation of EBTsVeterans Affairs residential treatment programsEvidence-based psychotherapiesUse of CPTInitial implementation effortsNatural courseEligible providersStress disorderNumber of providersPES useTime pointsLevel of trainingBaselineTherapyProvidersNational investigationNational trainersSignificant numberCase consultation
2013
Investigational anti-hyperglycemic agents: the future of type 2 diabetes therapy?
Majumdar SK, Inzucchi SE. Investigational anti-hyperglycemic agents: the future of type 2 diabetes therapy? Endocrine 2013, 44: 47-58. PMID: 23354728, DOI: 10.1007/s12020-013-9884-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsType 2 diabetesGlucose loweringCurrent therapiesFree Fatty Acid Receptor AgonistsNewer incretin-based therapiesGlucose cotransporter 2 inhibitorsDurable glycemic controlCotransporter 2 inhibitorsIncretin-based therapiesType 2 diabetes therapyIndividual patient characteristicsAcid receptor agonistsNew therapeutic classDiverse patient populationsMechanism of actionInsulin useComplex regimensPatient characteristicsGlycemic controlPatient populationType 1 inhibitorNatural courseReceptor agonistClinical trialsTreatment choice
2012
Evidence for an association between tumor necrosis factor-alpha levels and lithium response
Guloksuz S, Altinbas K, Cetin E, Kenis G, Gazioglu S, Deniz G, Oral E, van Os J. Evidence for an association between tumor necrosis factor-alpha levels and lithium response. Journal Of Affective Disorders 2012, 143: 148-152. PMID: 22749155, DOI: 10.1016/j.jad.2012.04.044.Peer-Reviewed Original ResearchConceptsTNF-α levelsBipolar patientsLithium responsePartial responseTumor necrosis factor-alpha levelsBipolar disorderTreatment-resistant bipolar patientsNecrosis factor-alpha levelsRole of inflammationPotential pathophysiological mechanismsAdditional inflammatory markersAssessment of responseGood responseEnzyme-linked immunosorbentEuthymic bipolar patientsImmune imbalanceImmune alterationsInflammatory markersImmune changesPathophysiological mechanismsPotential confoundersLithium therapyNatural coursePoor responseTreatment responseIs Intravitreal Bevacizumab an Effective Treatment Option for Nonarteritic Anterior Ischemic Optic Neuropathy?
Prescott CR, Sklar CA, Lesser RL, Adelman RA. Is Intravitreal Bevacizumab an Effective Treatment Option for Nonarteritic Anterior Ischemic Optic Neuropathy? Journal Of Neuro-Ophthalmology 2012, 32: 51-53. PMID: 22269947, DOI: 10.1097/wno.0b013e318240596e.Peer-Reviewed Original ResearchConceptsNonarteritic anterior ischemic optic neuropathyAnterior ischemic optic neuropathyIschemic optic neuropathyVisual acuityIntravitreal bevacizumabOptic neuropathyTreatment optionsIntravitreal bevacizumab injectionEffective treatment optionVisual field defectsBevacizumab injectionFellow eyesClinical outcomesRetrospective studyTreatment modalitiesNatural courseField defectsPatientsDecreased acuitySmall seriesAcuityBevacizumabProfound lossVisual fieldNeuropathy
2010
Osteopenia in Gaucher disease develops early in life: Response to imiglucerase enzyme therapy in children, adolescents and adults
Mistry PK, Weinreb NJ, Kaplan P, Cole JA, Gwosdow AR, Hangartner T. Osteopenia in Gaucher disease develops early in life: Response to imiglucerase enzyme therapy in children, adolescents and adults. Blood Cells Molecules And Diseases 2010, 46: 66-72. PMID: 21112800, PMCID: PMC3019260, DOI: 10.1016/j.bcmd.2010.10.011.Peer-Reviewed Original ResearchConceptsBone mineral densityDXA Z-scoresZ-scoreGaucher diseaseAge groupsYounger patientsNatural courseOlder adultsEnzyme therapyLumbar spine bone mineral densityInternational Collaborative Gaucher Group Gaucher RegistryLow bone mineral densitySpine bone mineral densityType 1 Gaucher diseaseYoung adultsDiverse bone diseasesLow bone densityPeak bone massHigh prevalence ratesAge of onsetMixed effects regression modelsGBA1 genotypeGaucher RegistryVisceral manifestationsDisease characteristics
2009
The underrecognized progressive nature of N370S Gaucher disease and assessment of cancer risk in 403 patients
Taddei TH, Kacena KA, Yang M, Yang R, Malhotra A, Boxer M, Aleck KA, Rennert G, Pastores GM, Mistry PK. The underrecognized progressive nature of N370S Gaucher disease and assessment of cancer risk in 403 patients. American Journal Of Hematology 2009, 84: 208-214. PMID: 19260119, PMCID: PMC3008404, DOI: 10.1002/ajh.21362.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge of OnsetBone Diseases, MetabolicChildCross-Sectional StudiesDisease ProgressionFemaleGaucher DiseaseGenetic HeterogeneityGenetic Predisposition to DiseaseGenotypeGlucosylceramidaseHumansHypergammaglobulinemiaIncidenceJewsMaleMiddle AgedMultiple MyelomaMutation, MissenseNeoplasmsOrgan SpecificityPhenotypePoint MutationRiskVisceraYoung AdultConceptsMultiple myelomaGaucher diseaseSkeletal diseaseRelative riskCancer riskType 1 Gaucher's diseaseCommon lysosomal storage disorderCross-sectional studyOverall cancer riskProgressive skeletal diseaseAdaptive immune systemLysosomal storage disorderAdult patientsEntire cohortLifetime riskNatural courseHematologic malignanciesRelative sparingHematologic diseasesHigh riskHigh incidencePatientsGBA1 geneHomozygous patientsImmune system
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