2024
Immunotherapy Initiation at the End of Life in Patients With Metastatic Cancer in the US
Kerekes D, Frey A, Prsic E, Tran T, Clune J, Sznol M, Kluger H, Forman H, Becher R, Olino K, Khan S. Immunotherapy Initiation at the End of Life in Patients With Metastatic Cancer in the US. JAMA Oncology 2024, 10: 342-351. PMID: 38175659, PMCID: PMC10767643, DOI: 10.1001/jamaoncol.2023.6025.Peer-Reviewed Original ResearchNon-small cell lung cancerEnd of lifeMonth of deathImmunotherapy initiationCohort studyMAIN OUTCOMEStage IV non-small cell lung cancerCharlson-Deyo comorbidity indexHigh metastatic burdenInitiation of immunotherapyNational prescribing patternsRisk-adjusted patientsImmune checkpoint inhibitorsRetrospective cohort studyStage IV melanomaPercentage of patientsHigh-volume centersLocation of metastasesLow-volume centersOdds of deathCell lung cancerNational Clinical DatabaseLow-volume facilitiesDrug Administration approvalCheckpoint inhibitors
2012
Non-operative management of acute cholecystitis in the elderly
McGillicuddy E, Schuster K, Barre K, Suarez L, Hall M, Kaml G, Davis K, Longo W. Non-operative management of acute cholecystitis in the elderly. British Journal Of Surgery 2012, 99: 1254-1261. PMID: 22829411, DOI: 10.1002/bjs.8836.Peer-Reviewed Original ResearchConceptsRecurrent acute cholecystitisAcute cholecystitisNon-operative managementDiagnosis of ACNon-operative groupAcute respiratory failureNon-operative treatmentTertiary care centerMonth of deathElective cholecystectomyIndex admissionInterval cholecystectomyOperative morbidityPostoperative morbidityRespiratory failureCholecystectomy ratesComplication ratePercutaneous cholecystostomyStandard therapyMajor complicationsPostoperative detailsMedical managementMyocardial infarctionMedical recordsPhysiological reserve
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