2025
Return on Investment of Enhanced Behavioral Health Services
Hawrilenko M, Smolka C, Ward E, Ambwani G, Brown M, Mohandas A, Paulus M, Krystal J, Chekroud A. Return on Investment of Enhanced Behavioral Health Services. JAMA Network Open 2025, 8: e2457834. PMID: 39908020, PMCID: PMC11800021, DOI: 10.1001/jamanetworkopen.2024.57834.Peer-Reviewed Original ResearchConceptsBehavioral health careBehavioral health servicesBehavioral health diagnosesHealth care costsHealth diagnosisBehavioral health benefitsProgram groupHealth servicesHealth careCare costsPhysical health care costsCohort studyMedical claimsMedical spendingBehavioral health appointmentsBehavioral health programsBehavioral health conditionsMental health diagnosesBehavioral health costsHealth benefitsDifference-in-differences analysisMedication risk scoreIn-person psychotherapyMedical cost savingsMedical managementPain Management in the Older Adults A Narrative Review
Rajput K, Ng J, Zwolinski N, Chow R. Pain Management in the Older Adults A Narrative Review. Clinics In Geriatric Medicine 2025, 41: 131-151. PMID: 39551538, DOI: 10.1016/j.cger.2024.03.011.Peer-Reviewed Original ResearchConceptsPain managementOlder adult populationOlder adult patientsOlder adultsAdult populationMultiple medicationsLife expectancyClinical practiceAdult patientsMedical managementPreexisting comorbiditiesPainUnited StatesDegenerative processPracticeNonagenariansMedicationAdultsComorbiditiesReviewManagementOctogenariansPatientsVascular Quality Initiative Assessment of Compliance with Society for Vascular Surgery Practice Guidelines for the Endovascular Management of Claudication
Iannuzzi J, Animilli S, Simons J, Tonnessen B, Koleilat I, Indes J, Conte M, Eldrup-Jorgensen J. Vascular Quality Initiative Assessment of Compliance with Society for Vascular Surgery Practice Guidelines for the Endovascular Management of Claudication. Journal Of Vascular Surgery 2025 PMID: 39824263, DOI: 10.1016/j.jvs.2025.01.007.Peer-Reviewed Original ResearchManagement of claudicationHospital-level variationGuideline releaseIncreased odds of smokingArea Deprivation IndexUptake of guidelinesChanges to clinical practiceOdds of smokingMedical managementSociety for Vascular SurgeryCases of claudicationHigh-grade recommendationsAlign careDeprivation indexImprove carePreoperative smoking cessationSmoking cessationMedical therapySocial deprivationDecreased oddsIncreased oddsSecondary analysisStent usePost-procedural recommendationsPractice guidelines
2024
Renovascular hypertension – a primer for the radiologist
Dixe de Oliveira Santo I, Sindoni J, Czeyda-Pommersheim F, Solomon N, Sailer A, Bhatt S, Fananapazir G, Pellerito J, Revzin M. Renovascular hypertension – a primer for the radiologist. Abdominal Radiology 2024, 1-13. PMID: 39542950, DOI: 10.1007/s00261-024-04677-y.Peer-Reviewed Original ResearchRenovascular hypertensionRenal arteryCause of renovascular hypertensionComputed tomography angiographyMagnetic resonance angiographyDiagnosing RVHExtrinsic compressionSecondary hypertensionRare conditionImaging findingsPolyarteritis nodosaSurgical interventionFibromuscular dysplasiaAnatomical variantsPage kidneyPictorial reviewHypertension casesAccurate diagnosisMedical managementDiagnostic criteriaTreatment approachesImaging modalitiesHypertensionImpact diagnosisYoung femalesEndovascular thrombectomy versus medical management for patients with large vessel stroke and infective endocarditis
Chen H, Colasurdo M, Khunte M, Malhotra A, Gandhi D. Endovascular thrombectomy versus medical management for patients with large vessel stroke and infective endocarditis. Journal Of NeuroInterventional Surgery 2024, jnis-2024-022374. PMID: 39317440, DOI: 10.1136/jnis-2024-022374.Peer-Reviewed Original ResearchEfficacy of endovascular thrombectomyLarge vessel occlusionInfective endocarditisPropensity score matchingIntracerebral hemorrhageSubarachnoid hemorrhageMedical managementMultivariable adjustmentOdds of intracerebral hemorrhageEndovascular thrombectomyHome dischargeRate of intracerebral hemorrhageFavorable hospital outcomesRate of in-hospital deathAssociated with significantly higher oddsLarge vessel occlusion strokeIn-hospital mortalityRoutine home dischargeIn-hospital deathRate of subarachnoid hemorrhageRate of home dischargeSignificantly higher oddsRate of routine dischargePrimary outcomeSecondary outcomesEndovascular thrombectomy versus medical management for acute basilar artery occlusion stroke in the elderly
Chen H, Colasurdo M, Khunte M, Malhotra A, Gandhi D. Endovascular thrombectomy versus medical management for acute basilar artery occlusion stroke in the elderly. American Journal Of Neuroradiology 2024, 46: ajnr.a8473. PMID: 39181691, PMCID: PMC11878975, DOI: 10.3174/ajnr.a8473.Peer-Reviewed Original ResearchPropensity score matchingBasilar artery occlusionIntracranial hemorrhageAssociated with higher ratesIn-hospital mortalityEndovascular thrombectomyIntravenous thrombolysisMedical managementAssociated with increased risk of ICHTreated with medical managementPatients treated with endovascular thrombectomyRisk of intracranial hemorrhageSafety of endovascular thrombectomyBasilar artery occlusion strokeFavorable hospital outcomesTreated with intravenous thrombolysisHome dischargeAssociated with increased riskEndovascular thrombectomy groupArtery occlusion strokeNational Inpatient SampleNIH Stroke ScalePropensity score-matched controlsStroke patientsHigher ratesEndovascular thrombectomy versus medical management for moderate-to-severe anterior cerebral artery occlusion stroke
Chen H, Khunte M, Malhotra A, Gandhi D, Colasurdo M. Endovascular thrombectomy versus medical management for moderate-to-severe anterior cerebral artery occlusion stroke. Journal Of Neurology 2024, 271: 6247-6254. PMID: 39085619, DOI: 10.1007/s00415-024-12582-z.Peer-Reviewed Original ResearchAssociated with higher oddsAnterior cerebral arteryAssociated with higher ratesIntracranial hemorrhageEndovascular thrombectomyMedical managementHigher oddsEfficacy of endovascular thrombectomyFavorable short-term outcomesRetrospective cohort studyPatient selection criteriaShort-term outcomesEndovascular thrombectomy patientsIn-hospital mortalityMultivariate logistic regressionHome dischargeArtery occlusion strokeNational Inpatient SampleHigher ratesNeurological outcomeCohort studyPrimary outcomeCerebral arterySecondary outcomesOcclusion strokeOrthopaedic Nurse Navigators and Total Joint Arthroplasty Preoperative Optimization
Kebeh M, Dlott C, Kurek D, Tung W, Morris J, Wiznia D. Orthopaedic Nurse Navigators and Total Joint Arthroplasty Preoperative Optimization. Orthopaedic Nursing 2024, 43: 195-201. PMID: 39047269, PMCID: PMC11279383, DOI: 10.1097/nor.0000000000001039.Peer-Reviewed Original ResearchConceptsNurse navigatorPayer statusMedical managementMedical management guidelinesMedication reconciliationResource referralsPatient educationInsurance statusPreoperative optimization protocolFinancial concernsInsurance coveragePatient outcomesLiterature searchNursesTJA patientsManagement guidelinesPayersMedicationStatusInsuranceFinancial resourcesEducationPatientsRecommendationsReferralPalliative Pharmacotherapy for Cardiovascular Disease: A Scientific Statement From the American Heart Association
Di Palo K, Feder S, Baggenstos Y, Cornelio C, Forman D, Goyal P, Kwak M, McIlvennan C, Nursing O. Palliative Pharmacotherapy for Cardiovascular Disease: A Scientific Statement From the American Heart Association. Circulation Cardiovascular Quality And Outcomes 2024, 17: e000131. PMID: 38946532, DOI: 10.1161/hcq.0000000000000131.Peer-Reviewed Original ResearchQuality of lifeCardiovascular diseaseExcess health care useGoal-oriented careHealth care useShared decision-makingEnhance quality of lifePalliative pharmacotherapyMedical managementScientific statementEvidence-based medical therapyPulmonary arterial hypertensionSpectrum of cardiovascular diseasesAmerican Heart AssociationCoronary heart diseaseEnd-stage heart failurePalliative medicineCare usePalliative approachArterial hypertensionGuideline-directedMedical therapyDevice therapyHeart failureWorsening symptomsPreoperative medication management turnkey order set for nonemergent adult cardiac surgery
Rea A, Salenger R, Grant M, Yeh J, Damas B, Crisalfi C, Arora R, Gregory A, Morton-Bailey V, Engelman D, Group E, Cangut B, Chatterjee S, Lobdell K, McConnell G, Crotwell S, Reddy S. Preoperative medication management turnkey order set for nonemergent adult cardiac surgery. JTCVS Open 2024, 22: 1-13. PMID: 39780789, PMCID: PMC11704528, DOI: 10.1016/j.xjon.2024.06.009.Peer-Reviewed Original ResearchSodium-glucose co-transporter-2Adult cardiac surgeryPreoperative medical managementGlucagon-like peptide-1Cardiac surgeryConsensus manuscriptNon-emergent cardiac surgeryMedical managementClass ICardiac surgical patientsCardiac surgical proceduresRisk of bleedingExpert consensus documentPreoperative managementPreoperative medicationsAnticoagulant medicationSurgical patientsSurgical proceduresSurgeryAnti-plateletPeptide-1Perioperative careConsensus documentCardiac SocietyManagement of patients' medicationPreoperative management of medications for psychiatric disorders.
Fernandez Robles C, Fernandez-Robles C, Oprea A. Preoperative management of medications for psychiatric disorders. Panminerva Medica 2024, 66: 281-292. PMID: 38757800, DOI: 10.23736/s0031-0808.24.05151-6.Peer-Reviewed Original ResearchThrombectomy vs Medical Management for Posterior Cerebral Artery Stroke: Systematic Review, Meta-Analysis, and Real-World Data.
Chen H, Khunte M, Colasurdo M, Malhotra A, Gandhi D. Thrombectomy vs Medical Management for Posterior Cerebral Artery Stroke: Systematic Review, Meta-Analysis, and Real-World Data. Neurology 2024, 102: e209315. PMID: 38626383, PMCID: PMC11175628, DOI: 10.1212/wnl.0000000000209315.Peer-Reviewed Original ResearchConceptsSymptomatic intracranial hemorrhagePosterior cerebral arteryAssociated with higher oddsNational Inpatient SampleEndovascular thrombectomyHigher oddsMedical managementCohort studyFunctional independencePosterior cerebral artery strokeSafety of endovascular thrombectomyOdds of symptomatic intracranial hemorrhageAssociated with significantly higher ratesOxford Centre for Evidence-Based Medicine criteriaRates of in-hospital mortalityCentre for Evidence-Based Medicine criteriaMeta-analysisRate of ICHAssociated with different oddsHigher odds of deathRate of subarachnoid hemorrhageIn-hospital mortalityAssociated with lower ratesClass III evidenceLevel of evidenceRetinal Ischemic Perivascular Lesions Are Associated With Myocardial Infarction in Patients With Coronary Artery Disease
Bousquet E, Santina A, Au A, Somisetty S, Abraham N, Voichanski S, Estawro R, Fouad Y, Romero-Morales V, Bakhoum M, Sarraf D. Retinal Ischemic Perivascular Lesions Are Associated With Myocardial Infarction in Patients With Coronary Artery Disease. American Journal Of Ophthalmology 2024, 264: 224-228. PMID: 38552932, DOI: 10.1016/j.ajo.2024.03.017.Peer-Reviewed Original ResearchCoronary artery diseaseSD-OCTBody mass indexMyocardial infarctionAssociated with MIMacular spectral-domain optical coherence tomographyMass indexPerivascular lesionsSpectral-domain optical coherence tomographyArtery diseaseSmoking statusMultivariate logistic regression analysisMedical management of coronary artery diseaseManagement of coronary artery diseaseOptical coherence tomographyNon-MI groupHistory of MIAssociated with myocardial infarctionLogistic regression analysisPotential clinical utilityConsecutive patientsOCT scansCoherence tomographyOdds ratioMedical managementEmergent Large Vessel Occlusion due to Intracranial Stenosis: Identification, Management, Challenges, and Future Directions
Al Kasab S, Nguyen T, Derdeyn C, Yaghi S, Amin-Hanjani S, Kicielinski K, Zaidat O, de Havenon A. Emergent Large Vessel Occlusion due to Intracranial Stenosis: Identification, Management, Challenges, and Future Directions. Stroke 2024, 55: 355-365. PMID: 38252763, DOI: 10.1161/strokeaha.123.043635.Peer-Reviewed Original ResearchConceptsIntracranial atherosclerotic stenosisVessel occlusionRecurrence riskEarly recurrence riskHigh-risk patientsAggressive medical managementRecurrent stroke riskEndovascular therapyHemodynamic failureTreatment strategiesPerfusion imagingAdvanced ageEndovascular interventionIntracranial stenosisMedical managementRisk factorsHigh riskAdvanced imagingAtherosclerotic stenosisStroke riskOcclusionStenosisPatientsRiskMediation of Age and Thrombectomy Outcome by Neuroimaging Markers of Frailty in Patients With Stroke
Benali F, Singh N, Fladt J, Jaroenngarmsamer T, Bala F, Ospel J, Buck B, Dowlatshahi D, Field T, Hanel R, Peeling L, Tymianski M, Hill M, Goyal M, Ganesh A, Barber P, Smith E, Bal S, Subramanian S, Peters S, Couillard P, Klein G, Stys P, Coutts S, Wong J, Mitha A, Eesa M, Morrish W, Alqatani S, Kashani N, Venkatesan P, Teleg E, Sitaram A, Graham B, Gaal S, Moussaddy A, Chakraborty D, Maraj N, Lockey A, Chen S, Singh R, Alsultan A, Asunsian R, Tse D, Doshi D, Volny O, Ojha P, Wadhwa A, Marko M, Singh N, Wasyliw S, Ryckborst K, Kenney C, Save S, Jambula A, Newcommon N, Hull G, Blackstock D, Kiszczak S, Zimmel L, Wright M, Jahraus C, Andersen L, Bohn S, Paul J, Buck B, Butcher K, Shuaib A, Jeerakathil T, Jickling G, Emery D, Rempel J, Ower R, Ashforth R, Yeo T, Kotylak T, O;Kelly C, Chow M, Siddiqui M, Saqqur M, D'Souza A, Lloret M, Butt A, Nomani A, Kalashyan H, Thirunavukkarasu S, Jabs J, Fairall P, Piquette L, Phillips S, Green A, Gubitz G, Heidenreich J, Huynh T, Shankar J, Maloney W, Vandorpe R, Schmidt M, Pickett G, Weeks A, Jarrett J, MacDonald D, Arsenault J, Kinnear R, Mandzia J, Mayich M, Boulton M, Bullrich M, Fridman S, Kiwan R, Lee D, Lownie S, Khaw A, Pandey S, Sharma M, Sposato L, Wade K, Beauchamp B, Lambourn L, Amato-Marziali B, Roy D, Deneault N, Deschaintre Y, Gioia L, Jacquin G, Odier C, Stapf C, Iancu D, Raymond J, Weill A, Lapierre M, Jadil N, Jolteus J, Teitelbaum J, Angle M, Hannouche M, Badawy M, Letourneau J, Cortes M, Linnell G, Tampieri D, Vieira L, Legault C, Durcan L, Moore A, Cole E, Magnussen C, Salmon K, Khalil S, Desloges I, Waxman L, Abdon W, Lai S, Dowlatshahi D, Shamy M, Stotts G, Blacquiere D, Lesiuk H, Quateen A, Drake B, Dewar B, Daham Z, Kelly M, Hunter G, Peeling L, Graham B, Whelan R, Garner A, Urroz L, Maley S, Silver F, Casaubon L, Pikula A, Campo M, Schaafsma J, Jaigobin C, Krings T, Pereira V, Agid R, Farb R, Kalman L, Cayley A, Williams J, Stewart T, Misquitta K, Bharatha A, Selchen D, Marotta T, Sarma D, Montanera W, Spears J, Saposnik G, Kostyrko P, Li Y, Parra-Farinas C, Diestro J, Camden M, Verreault S, Mackey A, Audet M, Milot G, Lavoie P, Gariépy J, Collard K, Haché A, Sahlas D, Alshanbari A, Baldwin J, Catanese L, Chen B, Sa Boasquevisque D, Deshmukh A, Knapman J, Lamers S, Larrazabal R, MacMillan S, Mai L, Mattai A, Nayar S, Ng K, Oczkowski W, Perera K, Shawawrah M, Shoamanesh A, Sobhi G, Syed N, Yaher N, Vandervelde C, Wang D, Field T, Van Gaal S, Teal P, Benavente O, Wilson L, Mann S, Yip S, Murphy C, Heran M, Rohr A, Settecase F, Redekop G, Haw C, Maclean G, Murray K, Chiu R, Flexman A, Strecha E, Gayton Y, Yip J, Swartz R, Boulos M, Gladstone D, Yu A, Hopyan J, Khosravani H, Manosalva Alzate H, Southwell A, Kamra M, Lopes K, Kapoor A, da Costa L, Yang V, Dyer E, Shah R, Knowles B, Nichols J, Patterson J, Cope K, Dickerson L, Barton K, Gray K, Massengale T, Miller M, Simpson C, Walker S, Tennyson-Yemm C, Frei D, Bellon R, Atchie B, Kaminsky I, Wilson D, Schraeder N, Arias E, Kodis L, Talley M, Edinger A, Talley T, Dempsey I, Williams L, Williams S, Kupniewski S, Fasbinder B, Snead J, Choe H, Mackenzie L, Weisman D, Kozak O, Shah Q, Gzesh D, Kulandaivel K, Khoury J, Klein B, Bussinger P, Griffin L, DePalmo A, Oliva C, Jadhav A, Jovin T, Kenmuir C, Jankowitz B, Gross B, Rocha M, Starr M, Brown M, Hawkes C, Shah K, Tememe D, Walker G, Patel P, Klein B, Ziayee H, Limaye K, Baxendell L, Glichrist V, Feineigle P, Toseki Haibach K, Van Every C, Desai S, Zulfiqar M, Gibson L, Barrett S, Turkel-Parrella D, Arcot K, DiCrescento S, Farkas J, Filipowski G, Frontera J, Joset D, Liff J, Scher E, McDougall C, Kelly C, Patel A, Monteith S, Starkman S, Atchaneeyasakul K, Burgos A, Anne Y. Chua J, Gaines N, Grunberg I, Guzy J, Liu Z, Maluste N, Ramirez L, Sharma L, Heck D, Brown M, McDonald C, Calderon M, Hargis M, Roels C, Emmady P, Alvi T, Jayaraman M, Cutting S, Smith W, Foley S, Paolucci G, Haas R, Quinn K, Fuller L, Brierley R, Watkins C, Demir N, Lopez G, Vargas A, Osteraas N, Holtz B, Sauvageau E, Aghaebrahim A, Chmayssani M, Naval N, Day J, Dellorso S, Ludwig B, Schemmel D, Ebreo N, Bell K, Lewis L, Delucia M, Haussen D, Frankel M, Bhatt N, Bianchi N, Anderson A, Belagaje S, Liberato B, Rangaraju S, Al-Bayati A, Grossber J, Craft L, Schindler K, Schaad E, Schultz M, Sutherly L, Doppelheuer S, Charlton J, Faggard J, Barbret Z, DukSoo Han E, Walters R, Dolia J, El-Jamal S, Eby B, Saleem Y, Pearl H, Patel K, Rahman H, Butt R, English S, Puri A, Howk M, Singh J, Massari F, DeMacedo Rodrigues K, Kuhn A, English J, Barazangi N, Telischak N, Kim W, Ross J, DeVole N, Redford J, Ferreira M, Ponting K, Shen H, Bedenk A, Patel S, Fernandess J, Ke M, Spokoyny I, Gao B, Tong D, Chen C, Wong C, Choe J, Martin C, Summers D, Boutwell C, Olds K, Crandall S, Eatman J, Akhtar N, Holloway W, Halpin J, Donegan B, Schindler J, Hwang D, Gilmore E, Petersen N, Sheth K, Brown S, Beekman R, George B, Kaddouh F, Falcone G, Wira C, Matouk C, Loomis C, Amin H, Stretz H, Narula R, Jasne A, Sansing L, Agarwal T, Jasak S, Fontaine B, King Z, Kouhn L, Orgass H, Leary M, Nye J, Halbert K, Nystrom K, Neuschatz K, Petrucci D, Coppola A, Joyce T, Hou S, Umekubo M, Nakamura C, Ovando R, Zuniga D, Nien Y, Basto F, Arch A, Jong L, Conrad W, Abbott T, Yao J, Caganap S, Jordan J, Teitelbaum G, Darflinger R, Kelly D, Gupta R, Budzik R, Czerniak J, Groezinger K, Hicks W, Kaskar O, Katz B, Loochtan A, Pema P, Rai V, Vora N, Brown A, Goodman D, Danenbergs B, Gossett M, Bang O, Chung J, Jeon P, Kim K, Lim Y, Hoe Heo J, Nam H, Kim Y, Park H, Hwang I, Ha W, Choi J, Jeong K, Rha J, Park H, Yoon C, Kim B, Sohn S, Kim C, Yoo J, Hong J, Park H, Kim S, Choi M, Bae H, Lee J, Lee J, Jun G, Jeon S, Campbell B, Mitchell P, Yassi N, Davis S, Donnan G, Parsons M, Yan B, Dowling R, Bush S, Wu T, Shan D, Zhao H, Salvaris P, Alemseged F, Ng F, Williams C, Balabanski A, dos Santos A, Ng J, McDonald A, Jackson D, Tsoleridis J, Pesavento L, Kleinig T, Drew R, Cranefield J, Scroop R, Cagi L, Harvey J, Waters M, Thornton J, Brennan R, O'Hare A, Power S, Williams D, Boyle K, Moynihan B, Liddy A, Large M, Cullen A, Walsh R, Martin E, Lynch J, McElroy S, Murphy S, Coveney S, Deegan C, Horgan G, Kelly P, Laffan A, Llamas-Osorio Y, Lynch C, Mac Mahon P, Marnane M, McCabe J, Burns P, Tauro S, Cuddy S, Rennie I, Smyth G, Flynn P, Wiggam I, Kerr E, Gordon P, Fearon P, Roberts G, Patterson C, Adams K, Wells B, McFarland M, Moreira T, Sjöstrand C, Mazya M, Almqvist H, Wahlgren N, Steinberg A, Cooray C, Eriksson E, Thorén M, Keselman B, Ahmed N, Holmberg Å, Axelsson M, Berglund A, Golsari A, Hoppe J, Deb-Chatterji M, Cheng B, Barow E, Schlemm E, Lettow I, Jensen M, Otto D, Jaramillo K, Appelbohm H, Fiehler J, Bester M, Schönfeld M, Brekenfeld C, Holst B, Wortmann G, Koch F, Gerber J, Abramyuk A, Kaiser D, Winzer S, Prakapenia A, Pallesen L, Siepmann T, Barlinn K, Haase K, Sauer A, Psychogios M, Liman J, Brehm A, Maus V, Hollstein N, Reinke A, Neitz G, Schnieder M, Schwarz M, Ibrahim A, Müller J, Meister S, Bäumle B, Chapot R, Pilgram-Pastor S, Wallocha M, Stauder M, Celik E, Stracke P, Müller N, Weber R, Veltkamp R, Nagel S, Ringleb P, Heyse M, Amiri H, Mundiyanapurath S, Chen M, Beyrle E, Beck P, Möhlenbruch M. Mediation of Age and Thrombectomy Outcome by Neuroimaging Markers of Frailty in Patients With Stroke. JAMA Network Open 2024, 7: e2349628. PMID: 38165676, PMCID: PMC10762575, DOI: 10.1001/jamanetworkopen.2023.49628.Peer-Reviewed Original ResearchConceptsMarker of frailtyEndovascular thrombectomyAlteplase treatmentCohort studyESCAPE-NA1 trialAcute ischemic strokeEarly ischemic changesSmall vessel diseaseBest medical managementAcute care hospitalsBrain frailtyFrailty featuresIschemic strokeStroke severityBrain atrophyCare hospitalIschemic changesPrimary outcomeClinical featuresMedical managementPuncture timeThrombectomy outcomesPoor outcomeVessel diseaseFunctional outcomePHENOTYPING REPAIR AFTER ACUTE KIDNEY INJURY: PRECISION MEDICINE TO CLINICAL TRIALS.
Parikh C, Hernandez J. PHENOTYPING REPAIR AFTER ACUTE KIDNEY INJURY: PRECISION MEDICINE TO CLINICAL TRIALS. Transactions Of The American Clinical And Climatological Association 2024, 134: 37-46. PMID: 39135588, PMCID: PMC11316880.Peer-Reviewed Original ResearchConceptsAcute kidney injuryChronic kidney diseaseKidney injuryEpisodes of acute kidney injuryAssociated with long-term riskLong-term risk of readmissionLong-term sequelaeRepair biomarkersRisk of readmissionSubclinical inflammationPreclinical studiesUrine biomarkersResearch biopsiesDeceased donor kidneysClinical trialsKidney diseaseBlood pressureMedical managementDonor kidneysPragmatic clinical trialsKidney tissueTherapeutic developmentOrgan allocationPrecision medicineKidney
2023
Radiographic Signs of Advanced Cerebral Venous Thrombosis Negatively Modulate the Effectiveness of Endovascular Treatments
Chen H, Khunte M, Colasurdo M, Singh P, Malhotra A, Gandhi D. Radiographic Signs of Advanced Cerebral Venous Thrombosis Negatively Modulate the Effectiveness of Endovascular Treatments. Cerebrovascular Diseases 2023, 53: 519-526. PMID: 37931607, DOI: 10.1159/000534821.Peer-Reviewed Original ResearchCerebral venous thrombosisGood discharge outcomeEndovascular treatmentRadiographic signsCVT patientsHospital mortalityVenous thrombosisDischarge outcomesMedical managementBetter outcomesSevere cerebral venous thrombosisNational Inpatient Sample databaseConservative medical managementPatient selection practicesPresence of infarctionShort-term effectivenessEVT patientsEVT treatmentParenchymal manifestationsMedical comorbiditiesMultivariable adjustmentCerebral infarctionPatient demographicsSecondary outcomesHospitalization outcomesCommon Issues for General Practitioners in the Medical Management of Child and Adolescent Psychiatric Care.
Banerjee A, Johnson B, Kauer A, Gunderson C, Stevens H. Common Issues for General Practitioners in the Medical Management of Child and Adolescent Psychiatric Care. The Journal Of Pediatric Pharmacology And Therapeutics 2023, 28: 595-602. PMID: 38025144, PMCID: PMC10681082, DOI: 10.5863/1551-6776-28.7.595.Peer-Reviewed Original ResearchTreatment of attention deficit hyperactivity disorderAttention deficit hyperactivity disorderDeficit hyperactivity disorderAdolescent psychiatric careHyperactivity disorderAdolescent psychiatryPsychiatric problemsAdolescent psychiatristsPsychiatric careSleep problemsGeneral practitionersClinical pearlsMedical managementYouth patientsPractical guidanceYouthMedicationChildrenCommon issuesPsychiatristsComputational phenotypes for patients with opioid-related disorders presenting to the emergency department
Taylor R, Gilson A, Schulz W, Lopez K, Young P, Pandya S, Coppi A, Chartash D, Fiellin D, D’Onofrio G. Computational phenotypes for patients with opioid-related disorders presenting to the emergency department. PLOS ONE 2023, 18: e0291572. PMID: 37713393, PMCID: PMC10503758, DOI: 10.1371/journal.pone.0291572.Peer-Reviewed Original ResearchConceptsSubstance use disordersUse disordersED visitsPatient presentationCarlson comorbidity indexOpioid-related diagnosesOpioid-related disordersOne-year survivalRate of medicationOpioid use disorderElectronic health record dataPatient-oriented outcomesYears of ageHealth record dataChronic substance use disordersED returnComorbidity indexAcute overdoseMedical managementClinical entityRetrospective studyEmergency departmentChronic conditionsInclusion criteriaUnique cohortAssessing Clinical Utility of Pharmacogenetic Testing in the Military Health System
Hellwig L, Turner C, Olsen C, Libbus J, Markos B, Koehlmoos T, Haigney M, De Castro M, Saunders D. Assessing Clinical Utility of Pharmacogenetic Testing in the Military Health System. Military Medicine 2023, 189: e198-e204. PMID: 37436924, PMCID: PMC11022329, DOI: 10.1093/milmed/usad254.Peer-Reviewed Original ResearchMilitary Health SystemPharmacogenetic testingAdverse eventsCPIC guidelinesPGx testingHealth systemCurrent medication regimensPreemptive PGx testingPrimary care clinicsPreventable adverse eventsAdverse drug reactionsLarge military treatment facilitySubstantial proportionCross-sectional studyMilitary treatment facilitiesMedication metabolismPGx implementationMedication regimensRisk medicationsSerious morbidityCare clinicsMedical managementMedication listPGx resultsSingle center
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