2025
Lower Extremity Flow Quantification Using Dynamic 82Rb PET: a Preclinical Investigation
Guo L, Thorn S, de Rubio Cruz P, Liu Z, Gallezot J, Liu Q, Moulton E, Carson R, Sinusas A, Liu C. Lower Extremity Flow Quantification Using Dynamic 82Rb PET: a Preclinical Investigation. IEEE Transactions On Radiation And Plasma Medical Sciences 2025, PP: 1-1. DOI: 10.1109/trpms.2025.3542729.Peer-Reviewed Original Research
2024
Methods to Manage Edema and Reduce Flap Compression in Postoperative Nursing Care Following Trauma to the Lower Extremity
Rancu A, Darby F, Averbukh L, Nicholson A, Myrick K, Leslie M, Wiznia D. Methods to Manage Edema and Reduce Flap Compression in Postoperative Nursing Care Following Trauma to the Lower Extremity. Orthopaedic Nursing 2024, 43: 325-329. PMID: 39630519, DOI: 10.1097/nor.0000000000001075.Peer-Reviewed Original Research In PressConceptsLower extremity traumaExtremity traumaAcute care settingPostoperative nursing careNurse managersOrthopaedic nursesNursing careSoft tissue coverage techniquesPostoperative nursing managementCare settingsLower-extremitySoft tissue coverage proceduresLower extremitiesReduce edemaPoor soft tissue healingTraumatic injuryLiterature reviewTraumaNursesExtremitiesLower extremity edemaPatientsCareSoft tissue healingReviewSpesolimab decreases generalized pustular psoriasis (GPP) body surface area (BSA) over time in patients switching from conventional systemic treatments: Results from the EFFISAYIL® 2 trial
Merola J, Strober B, Gottlieb A, Mostaghimi A, Hawkes J, Guercio J, Tang M, Thoma C, Lebwohl M. Spesolimab decreases generalized pustular psoriasis (GPP) body surface area (BSA) over time in patients switching from conventional systemic treatments: Results from the EFFISAYIL® 2 trial. SKIN The Journal Of Cutaneous Medicine 2024, 8: s488. DOI: 10.25251/skin.8.supp.488.Peer-Reviewed Original ResearchGeneralized pustular psoriasisBody surface areaBody surface area involvementSystemic medicationsConventional systemic treatmentsAverage body surface areaTreating generalized pustular psoriasisLife-threatening skin diseaseSignificant patient burdenYears of ageSystemic therapyDosing regimenSystemic treatmentPediatric patientsPustular psoriasisExtent of involvementSpesolimabWeek 4Skin symptomsPatientsMonoclonal antibodiesLower extremitiesSkin diseasesPatient burdenUpper extremitySpesolimab decreases generalized pustular psoriasis (GPP) body surface area (BSA) over time in patients with various lengths of disease history: Results from the EFFISAYIL® 2 trial
Mostaghimi A, Strober B, Merola J, Gottlieb A, Elewski B, Guercio J, Tang M, Thoma C, Lebwohl M. Spesolimab decreases generalized pustular psoriasis (GPP) body surface area (BSA) over time in patients with various lengths of disease history: Results from the EFFISAYIL® 2 trial. SKIN The Journal Of Cutaneous Medicine 2024, 8: s489. DOI: 10.25251/skin.8.supp.489.Peer-Reviewed Original ResearchGeneralized pustular psoriasisBody surface areaBody surface area involvementWeek 4Disease historyAverage body surface areaTreating generalized pustular psoriasisYear prior to enrollmentLife-threatening skin diseaseSignificant patient burdenYears of ageDosing regimenPediatric patientsPustular psoriasisExtent of involvementSpesolimabDisease courseSkin symptomsPatientsMonoclonal antibodiesLower extremitiesSkin diseasesPatient burdenUpper extremityTime pointsSpesolimab decreases generalized pustular psoriasis (GPP) body surface area (BSA) over time: Results from the EFFISAYIL® 2 trial
Strober B, Merola J, Gottlieb A, Mostaghimi A, Hsiao J, Guercio J, Tang M, Thoma C, Lebwohl M. Spesolimab decreases generalized pustular psoriasis (GPP) body surface area (BSA) over time: Results from the EFFISAYIL® 2 trial. SKIN The Journal Of Cutaneous Medicine 2024, 8: s491. DOI: 10.25251/skin.8.supp.491.Peer-Reviewed Original ResearchGeneralized pustular psoriasisBody surface areaBody surface area involvementTreating generalized pustular psoriasisLife-threatening skin diseaseArea of involvementSignificant patient burdenYears of ageDosing regimenPediatric patientsPustular psoriasisExtent of involvementSpesolimabSkin symptomsContinuous treatmentPatientsMonoclonal antibodiesLower extremitiesSkin diseasesPatient burdenUpper extremityTime pointsTreatmentInvolvementBody regionsEP049 Lower extremity enhanced nerve analgesia (LEENA): a novel 4-in-1 peripheral nerve block of the lower extremity
Alrayashi W, Sane M, Pelt H, McGinn C, Staffa S. EP049 Lower extremity enhanced nerve analgesia (LEENA): a novel 4-in-1 peripheral nerve block of the lower extremity. 2024, a95-a97. DOI: 10.1136/rapm-2024-esra.122.Peer-Reviewed Original ResearchRobotic-Assisted Microsurgery in Lymphatic Reconstruction
Stögner V, Pucciarelli D, Pomahac B, Ayyala H. Robotic-Assisted Microsurgery in Lymphatic Reconstruction. Journal Of Craniofacial Surgery 2024, 36: 359-362. PMID: 39283135, DOI: 10.1097/scs.0000000000010608.Peer-Reviewed Original ResearchLymphatic reconstructionRobotic-assisted microsurgeryBreast cancer-related lymphedemaCancer-related lymphedemaSurgical outcomesYears of clinical experienceMicrosurgical reconstructionPatient groupLymphatic flowCancer incidenceSurvival rateLymphatic anastomosisMicrosurgical performanceClinical experienceMicrosurgeryLower extremitiesHuman vesselsLymphatic microsurgeryPatientsMicrosurgical robotPhysiological tremorA Rare Pediatric Mandibular Mass: Diagnosis, Treatment and Reconstruction: A Case Report
Susan S, Gorman L, Santore E, Boldikova D, Ibrahim G, Kravchenko D, Khan M, Johnson D, Mehra S, Laskin W, Eskendri J. A Rare Pediatric Mandibular Mass: Diagnosis, Treatment and Reconstruction: A Case Report. Oral Surgery Oral Medicine Oral Pathology And Oral Radiology 2024, 138: e63. DOI: 10.1016/j.oooo.2024.04.096.Peer-Reviewed Original ResearchSclerosing epithelioid fibrosarcomaFibular free flap reconstructionHigh risk of metastasisAggressive clinical courseMetastasis 9 monthsRisk of metastasisEpisodes of recurrenceFree flap reconstructionMalignant fibroblastic neoplasmExcisional surgeryClinical courseFlap reconstructionHyalinized stromaAdjunctive therapyPoor prognosisSurgical siteEpithelioid cellsTreatment planningMiddle aged adultsTreatment protocolsFibroblastic neoplasmRight mandibleHigh riskMUC4 immunoreactivityLower extremitiesManifestations of human atherosclerosis across vascular beds
Jovin D, Sumpio B, Greif D. Manifestations of human atherosclerosis across vascular beds. JVS-Vascular Insights 2024, 2: 100089. PMID: 39822712, PMCID: PMC11737335, DOI: 10.1016/j.jvsvi.2024.100089.Peer-Reviewed Original ResearchVascular bedClinical managementCarotid arteryCommon risk factorsPeripheral arterial diseaseManagement of carotidClinical management of atherosclerosisEtiology of mortalityIntervention outcomesModel of atherogenesisPathology of atherosclerotic lesionsMedical therapyMeta-analysesTreatment responseFibrotic componentManagement of atherosclerosisLower extremitiesMale sexClinical studiesArtery diseaseMetabolic factorsPeripheral atherosclerosisRisk factorsIndividual patientsVascular territoriesReduced Muscle Mass and Muscle Quality in Patients with Intermittent Claudication due to Peripheral Artery Disease
Nishibe T, Dardik A, Akiyama S, Kano M, Fukuda S, Koizumi J, Nishibe M. Reduced Muscle Mass and Muscle Quality in Patients with Intermittent Claudication due to Peripheral Artery Disease. Annals Of Vascular Surgery 2024, 105: 275-281. PMID: 38570014, DOI: 10.1016/j.avsg.2023.12.094.Peer-Reviewed Original ResearchSkeletal muscle massPeripheral arterial diseaseBioelectrical impedance analysisAnkle-brachial indexAnkle-brachial pressure indexLeg skeletal muscle massLeg ischemiaMuscle massIntermittent claudicationLeg muscle massMuscle qualityArtery diseaseAssociated with reduced muscle massTokyo Medical University HospitalAssociated with skeletal muscle myopathyReduced muscle massMedical University HospitalLeg muscle qualitySkeletal muscle myopathyUniversity HospitalMuscle myopathyPatientsIschemiaClaudicationLower extremitiesHTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP): Case based discussion of risk factors, clinical, and therapeutic considerations
Saab L, DiCapua D, Zubair A. HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP): Case based discussion of risk factors, clinical, and therapeutic considerations. Journal Of The Neurological Sciences 2024, 459: 122973. PMID: 38520941, DOI: 10.1016/j.jns.2024.122973.Peer-Reviewed Original ResearchHTLV-1-associated myelopathy/tropical spastic paraparesisMyelopathy/tropical spastic paraparesisHTLV-1Discussion of risk factorsInfected CD4+ T cellsCD4+ T cellsAdult T-cell leukemia/lymphomaSpastic paraparesisT-cell leukemia/lymphomaQuality of lifeOptimal patient outcomesHTLV-1 infectionSymptoms of weaknessManaging symptomsDuration of infectionLoss of bladder controlNonspecific symptomsT cellsLower extremitiesSensory disturbancePatient outcomesTherapeutic considerationsHAM/TSPProviral loadRisk factors
2023
Successful mechanical thrombectomy for terminal ICA bullet embolism: A case report.
Clouse J, Thaci B, Clark A, Baggett M, Raslan O, Matouk C, Waldau B, Cord B. Successful mechanical thrombectomy for terminal ICA bullet embolism: A case report. Interventional Neuroradiology 2023, 15910199231219021. PMID: 38073079, DOI: 10.1177/15910199231219021.Peer-Reviewed Original ResearchMechanical thrombectomyBullet embolismBullet fragmentsMiddle cerebral arterySuccessful mechanical thrombectomyLeft-sided hemiparesisRight M1 segmentMultiple gunshot woundsProper resuscitationIschemic eventsCerebral arteryCase reportHead injuryTomography angiographyM1 segmentLower extremitiesForeign bodyGunshot woundsThrombectomyBlood vesselsEmbolismInjuryDistalRare eventVesselsAn ultrasound-based femoral artery calcification score
Maahs E, Schwartz A, Berezowitz A, Davis S, Guzman R. An ultrasound-based femoral artery calcification score. Journal Of Vascular Surgery Cases And Innovative Techniques 2023, 10: 101381. PMID: 38130366, PMCID: PMC10731664, DOI: 10.1016/j.jvscit.2023.101381.Peer-Reviewed Original ResearchPeripheral arterial diseaseCalcification scoreArterial diseaseLower extremitiesFemoral calcificationCalcium scoreDuplex ultrasoundFemoral arteryChronic limb threatening ischemiaArterial duplex ultrasoundFemoral artery calcificationLimb-specific outcomesAmputation-free survivalLimb threatening ischemiaLower extremity atherosclerosisStandard computed tomographyNew scoring systemArtery calcificationLimb outcomesRenal failureCT evaluationArterial calcificationInclusion criteriaComputed tomographyUS scoreAssessment of changes in blood volume during lower body negative pressure-induced hypovolemia using bioelectrical impedance analysis
Anakmeteeprugsa S, Gonzalez-Fiol A, Vychodil R, Shelley K, Alian A. Assessment of changes in blood volume during lower body negative pressure-induced hypovolemia using bioelectrical impedance analysis. Journal Of Clinical Monitoring And Computing 2023, 38: 293-299. PMID: 37966562, DOI: 10.1007/s10877-023-01098-y.Peer-Reviewed Original ResearchEstimated blood lossBioelectrical impedance analysisBlood lossHealthy volunteersBlood volumeProspective observational studyBody negative pressureSignificant increaseT-testStudent's t-testAcute hemorrhageLBNP protocolLower extremitiesObservational studyHypovolemiaLBNPCompensatory mechanismsPercentage changeReciprocal changesSignificant decreaseBioimpedanceBaselineSignificant correlationMmHgP-valueThe Potential Role of PET in the Management of Peripheral Artery Disease
Alashi A, Vermillion B, Sinusas A. The Potential Role of PET in the Management of Peripheral Artery Disease. Current Cardiology Reports 2023, 25: 831-839. PMID: 37314651, PMCID: PMC11542486, DOI: 10.1007/s11886-023-01904-8.Peer-Reviewed Original ResearchConceptsPeripheral artery diseaseArtery diseaseLower extremitiesManagement of PADSetting of PADEarly detectionLarge vessel diseaseManagement of patientsNon-invasive testsPositron emission tomography (PET) imagingEmission Tomography ImagingNon-invasive toolVascular inflammationVessel diseaseMicrovascular perfusionRoutine screeningBlood flowClinical researchPatientsDiseaseTomography imagingPET imagingSkeletal musclePotential roleSummaryThe purpose
2022
Cryptogenic acute lower extremities and multiorgan ischemia in an 8-year-old girl
Setia O, Chan SM, Ullrich S, Hornick MA, Chaar C. Cryptogenic acute lower extremities and multiorgan ischemia in an 8-year-old girl. Journal Of Vascular Surgery Cases And Innovative Techniques 2022, 8: 565-568. PMID: 36248384, PMCID: PMC9556621, DOI: 10.1016/j.jvscit.2022.08.020.Peer-Reviewed Original ResearchAcute limb ischemiaLimb ischemiaBilateral lower extremity ischemiaAcute lower extremityTraumatic vessel injuryLower extremity ischemiaPediatric age groupMultiple visceral organsInterdisciplinary workupMultiorgan ischemiaExtremity ischemiaCardiac catheterizationEmbolic eventsIatrogenic injuryLower extremitiesVessel injuryCommon causeVisceral organsIschemiaTimely interventionAge groupsInjuryGirlsDevastating effectsRevascularizationBiallelic BICD2 variant is a novel candidate for Cohen-like syndrome
Caglayan AO, Tuysuz B, Gül E, Alkaya DU, Yalcinkaya C, Gleeson JG, Bilguvar K, Gunel M. Biallelic BICD2 variant is a novel candidate for Cohen-like syndrome. Journal Of Human Genetics 2022, 67: 553-556. PMID: 35338243, PMCID: PMC9420744, DOI: 10.1038/s10038-022-01032-1.Peer-Reviewed Original ResearchConceptsWhole-exome sequencing analysisTruncal obesityJoint hypermobilityLower extremitiesHomozygous missense mutationSevere formBICD2 mutationsType 2BHeterozygous mutationsSpeech delayType 2AIntellectual disabilityPatientsSyndromeConsanguineous unionsMissense mutationsNovel candidatesSequencing analysisFirst reportMutationsExpanding the criteria for targeted muscle reinnervation: A national assessment of eligibility
Junn A, Dinis J, Reategui A, Liu S, Colen D, Prsic A. Expanding the criteria for targeted muscle reinnervation: A national assessment of eligibility. Orthoplastic Surgery 2022, 7: 7-12. DOI: 10.1016/j.orthop.2021.10.003.Peer-Reviewed Original ResearchPeripheral vascular diseaseVascular diseaseMuscle reinnervationKnee amputationLower extremitiesICD-9 diagnosis codesNational Inpatient Sample databaseHospital-level factorsLower extremity amputationLowest income quartileOlder patientsYounger patientsBlack patientsExtremity amputationPatient populationDiagnosis codesHigh prevalenceInclusion criteriaLE amputationEighth decadePatientsAmputationOverall populationIncome quartileStudy period
2021
Erosion of Common Femoral Artery 3 Years After Total Hip Arthroplasty in a Patient with Marfan Syndrome
Kammien A, Radford Z, Aboian E, Kostiuk V, Gibson D. Erosion of Common Femoral Artery 3 Years After Total Hip Arthroplasty in a Patient with Marfan Syndrome. JBJS Case Connector 2021, 11: e21.00208. PMID: 35102090, DOI: 10.2106/jbjs.cc.21.00208.Peer-Reviewed Original ResearchConceptsTotal hip arthroplastyHip arthroplastyMarfan syndromeImpaired vascular integrityLeft lower extremityCongenital hip dysplasiaConnective tissue disordersUnusual vascular complicationProper implant positioningArtery embolismProsthetic erosionArtery dilationVascular complicationsRare complicationOpen repairIntravenous ultrasoundSimilar patientsAcute ischemiaLower extremitiesTissue disordersHigh riskHip dysplasiaImplant positioningIntraluminal thrombusPatientsCreation of an Evidence-Based Physical Therapy Program for Adults with XLH: Translational Application of an Interprofessional Clinical Study
Kanamalla K, Fuchs R, Herzog C, Steigbigel K, Macica C. Creation of an Evidence-Based Physical Therapy Program for Adults with XLH: Translational Application of an Interprofessional Clinical Study. Journal Of The Endocrine Society 2021, 5: a260-a260. PMCID: PMC8089516, DOI: 10.1210/jendso/bvab048.528.Peer-Reviewed Original ResearchLower Extremity Functional ScaleBerg Balance ScaleBalance ScaleActivities-specific Balance Confidence ScaleLifelong metabolic diseasePT programBalance Confidence ScaleIntestinal phosphate absorptionPhysical therapy programMusculoskeletal comorbiditiesStandard therapyClinical pictureBalance exercisesDegenerative arthritisActive ROMLower extremitiesClinical studiesFunctional scalesDaily livingFunctional capacityFunctional abilityFunctional comorbiditiesTrunk swayAdult disordersMetabolic diseases
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