2025
Benzodiazepine Initiation and the Risk of Falls or Fall-Related Injuries in Older Adults Following Acute Ischemic Stroke
Sun S, Lomachinsky V, Smith L, Newhouse J, Westover M, Blacker D, Schwamm L, Haneuse S, Moura L. Benzodiazepine Initiation and the Risk of Falls or Fall-Related Injuries in Older Adults Following Acute Ischemic Stroke. Neurology Clinical Practice 2025, 15: e200452. PMID: 40144887, DOI: 10.1212/cpj.0000000000200452.Peer-Reviewed Original ResearchFall-related injuriesRisk of fallsOlder adultsAcute ischemic strokeRisk differenceAcute ischemic stroke admissionsElectronic health recordsHypothetical randomized trialInverse probability weightingIschemic strokeRecovery periodHealth recordsBenzodiazepine initiationPoststroke periodConfounding biasImmortal timeMild strokeBenzodiazepine prescriptionsBZD useDay of admissionProbability weightingSubgroup analysisAnalyzed dataStrokeAdultsAn atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis
El Bounkari O, Zan C, Yang B, Ebert S, Wagner J, Bugar E, Kramer N, Bourilhon P, Kontos C, Zarwel M, Sinitski D, Milic J, Jansen Y, Kempf W, Sachs N, Maegdefessel L, Ji H, Gokce O, Riols F, Haid M, Gerra S, Hoffmann A, Brandhofer M, Avdic M, Bucala R, Megens R, Willemsen N, Messerer D, Schulz C, Bartelt A, Harm T, Rath D, Döring Y, Gawaz M, Weber C, Kapurniotu A, Bernhagen J. An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis. Nature Communications 2025, 16: 2297. PMID: 40055309, DOI: 10.1038/s41467-025-57540-z.Peer-Reviewed Original ResearchConceptsApoE-/- miceHyperlipidemic apoE-/- miceCoronary artery diseaseDecreased plasma lipid levelsPlasma lipid levelsHepatic lipid accumulationAtherogenic chemokinesFoam-cell formationFLIM-FRET microscopyArtery diseasePlasma concentrationsVascular inflammationInflammatory conditionsMetabolic dysfunctionAtherosclerotic patientsLipid accumulationAdvanced atherosclerosisMyocardial infarctionLipid levelsSuppressed hepatic lipid accumulationAdvanced atherogenesisCarotid plaquesDisease severityIschemic strokeChemokinesDetectability of acute ischemic stroke with thin (3 mm) axial versus thin (3 mm) coronal diffusion-weighted imaging in patients presenting to the emergency department with acute dizziness
Lozano R, Shareef F, Neupane A, Siddique Z, Joshi R, Pasquini L, Tu L, Mahajan A. Detectability of acute ischemic stroke with thin (3 mm) axial versus thin (3 mm) coronal diffusion-weighted imaging in patients presenting to the emergency department with acute dizziness. Emergency Radiology 2025, 1-7. PMID: 40053160, DOI: 10.1007/s10140-025-02327-4.Peer-Reviewed Original ResearchAxial DWIIschemic lesionsMRI examinationsDetection of brain ischemiaEmergency departmentIschemic strokeMiddle cerebellar peduncleRetrospective cohort studyDiffusion-weighted imagingAcute ischemic strokeDetection of acute ischemic strokeDetection of ischemiaMethodsRetrospective studyPosterior circulationAxial MRIDWI sequencesAcute dizzinessCerebellar pedunclePurposeIschemic strokeCoronal sequencesCohort studyDiagnostic utilityMRI protocolMcNemar testBrain ischemiaApixaban to Prevent Covert Infarcts After Cryptogenic Stroke in Patients With Atrial Cardiopathy
Lansberg M, Wintermark M, Chen H, Howard G, Cassarly C, Pauls Q, Kemp S, Harris T, Krishnaiah B, Stanton R, Lyerly M, Miller B, Smith E, Tirschwell D, Sheth K, Kamel H, Longstreth W, Elkind M, Broderick J, Lazar R. Apixaban to Prevent Covert Infarcts After Cryptogenic Stroke in Patients With Atrial Cardiopathy. JAMA Neurology 2025, 82: 220-227. PMID: 39869342, PMCID: PMC11773411, DOI: 10.1001/jamaneurol.2024.4838.Peer-Reviewed Original ResearchConceptsCovert infarctsResearch magnetic resonance imagingCompletion of participationParticipant completionAtrial cardiopathyMain OutcomesParent studyRandomized clinical trialsPrimary outcomeFollow-up magnetic resonance imagingMagnetic resonance imagingParticipantsFollow-up periodRecurrent strokeStrokeIschemic strokeFollow-upBaseline characteristicsAncillary studiesCryptogenic strokeBaselineInsufficient qualityPreventionInfarctionIQRSilent Myocardial Infarction and Risk of Stroke Recurrence: A Post Hoc Analysis of the IRIS Trial.
Ridha M, Zhang C, McCullough S, Viscoli C, Sharma R, Kamel H, Merkler A. Silent Myocardial Infarction and Risk of Stroke Recurrence: A Post Hoc Analysis of the IRIS Trial. Journal Of The American Heart Association 2025, 14: e037663. PMID: 39921499, DOI: 10.1161/jaha.124.037663.Peer-Reviewed Original ResearchConceptsSilent MISilent myocardial infarctionStroke recurrenceClinical MIAssociated with stroke recurrenceFirst-ever strokeMyocardial infarctionIschemic strokeTailored prevention strategiesRecurrent strokeVascular risk factorsHistory of hospitalizationRisk of stroke recurrenceEvidence of MIUnadjusted analysisPrevention strategiesInclusion criteriaSecondary outcomesECG evidence of MIPrimary outcomeRisk factorsMultivariate Cox regression analysisPost hoc analysisStrokeRegression analysisThe Impact of Aortic Arch Morphology on Periprocedural Stroke in Transcatheter Aortic Valve Replacement
Voss S, Rusa K, Campanella C, Georgescu T, Vitanova K, Ruge H, Amabile A, Sideris K, Krane M, Burri M. The Impact of Aortic Arch Morphology on Periprocedural Stroke in Transcatheter Aortic Valve Replacement. Journal Of Clinical Medicine 2025, 14: 1045. PMID: 40004577, PMCID: PMC11856225, DOI: 10.3390/jcm14041045.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementMulti-slice computed tomographyAortic valve replacementAortic arch morphologyArch anatomyValve replacementPeriprocedural strokeLeft common carotid arteryTransfemoral transcatheter aortic valve replacementEpi-aortic vesselsIschemic strokeArch morphologyPeriprocedural ischemic strokePropensity-matched case-control studyScore-matched studyCase-control studyCommon carotid arteryOccurrence of ischemic strokeAortic arch geometryEuroSCORE IIPropensity score matchingAortic archComparing patientsCatheter manipulationCarotid arteryEmergent Carotid Stenting During Thrombectomy in Tandem Occlusions Secondary to Dissection: A STOP-CAD Secondary Study
Sousa J, Rodrigo-Gisbert M, Shu L, Luo A, Xiao H, Mahmoud N, Shah A, Santos A, Moore M, Mandel D, Heldner M, Barata V, Bernardo-Castro S, Henninger N, Muppa J, Arnold M, Nehme A, Rothstein A, Khazaal O, Kaufmann J, Engelter S, Traenka C, Metanis I, Leker R, Nolte C, Ghannam M, Samaniego E, Almajali M, Poppe A, Romoli M, Frontera J, Zedde M, Kam W, Mac Grory B, Velez F, Ranasinghe T, Siegler J, Zubair A, Marto J, Klein P, Nguyen T, Abdalkader M, Mantovani G, Simpkins A, Sen S, Elnazeir M, Yaghi S, Sargento-Freitas J, Requena M. Emergent Carotid Stenting During Thrombectomy in Tandem Occlusions Secondary to Dissection: A STOP-CAD Secondary Study. Stroke 2025, 56: 808-817. PMID: 39882629, DOI: 10.1161/strokeaha.124.048295.Peer-Reviewed Original ResearchConceptsSymptomatic intracranial hemorrhageCarotid artery dissectionEmergent carotid stentingIntracranial recanalizationAcute ischemic strokeCervical carotid artery dissectionEndovascular treatmentIntracranial hemorrhageTandem occlusionEmergency stentingArtery dissectionCarotid stentingIschemic strokeAnterior circulation acute ischemic strokePatients treated with endovascular treatmentIncreased symptomatic intracranial hemorrhageAlberta Stroke Program Early CT ScoreCervical carotid dissectionInverse probability of treatment weightingFunctional independenceProbability of treatment weightingNational Institutes of Health Stroke ScaleSecondary to dissectionHealth Stroke ScaleMixed-effects logistic regressionComparative efficacy and safety of stent retrievers as a bailout strategy following failed contact aspiration technique in acute stroke thrombectomy
Ezzeldin M, Hukamdad M, Kasem R, Ezzeldin R, Maier I, T A, Jabbour P, Kim J, Howard B, Alawieh A, Wolfe S, Starke R, Psychogios M, Shaban A, Goyal N, Dye J, Alaraj A, Yoshimura S, Fiorella D, Tanweer O, Romano D, Navia P, Cuellar H, Fragata I, Polifka A, Mascitelli J, Osbun J, Siddiqui F, Moss M, Limaye K, Mokin M, Matouk C, Park M, Brinjikji W, Daglioglu E, Williamson R, Altschul D, Ogilvy C, Crosa R, Levitt M, Gory B, Grandhi R, Paul A, Kan P, Casagrande W, Chowdhry S, Stiefel M, Chaubal V, Spiotta A. Comparative efficacy and safety of stent retrievers as a bailout strategy following failed contact aspiration technique in acute stroke thrombectomy. Journal Of NeuroInterventional Surgery 2025, jnis-2024-022781. PMID: 39884851, DOI: 10.1136/jnis-2024-022781.Peer-Reviewed Original ResearchSymptomatic intracranial hemorrhageTrevo stent retrieverContact aspirationStent retrieverAcute ischemic strokeEndovascular thrombectomyRecanalization rateFunctional outcomesAssociated with higher recanalization ratesOdds of symptomatic intracranial hemorrhageHigher recanalization ratesAssociated with higher oddsEndovascular thrombectomy patientsContact aspiration techniqueIntracranial hemorrhageMulticenter registryRecanalizationReduced oddsStroke thrombectomyHigher oddsIschemic strokeThrombectomyAspiration techniqueBailout strategyOddsTransient Ischemic Attack in Women: Real-World Hospitalization Incidence, Outcomes, and Risk of Hemorrhage and Stroke
Chen H, Khunte M, Colasurdo M, Majmundar S, Payabvash S, Chaturvedi S, Malhotra A, Gandhi D. Transient Ischemic Attack in Women: Real-World Hospitalization Incidence, Outcomes, and Risk of Hemorrhage and Stroke. Stroke 2025, 56: 285-293. PMID: 39869710, DOI: 10.1161/strokeaha.124.049278.Peer-Reviewed Original ResearchConceptsRates of vascular risk factorsTransient ischemic attackUS Census Bureau dataAssociated with lower oddsHigher odds of deathIschemic strokeRisk factorsAnnual incidenceTransient neurological symptomsStroke risk factorsOdds of deathLogistic regression modelsVascular risk factorsCensus Bureau dataRate of headacheRetrospective cohort studyLower oddsHigher oddsNeurological symptomsHome dischargeCohort studyIschemic attackHospital incidenceExcess hospitalizationsRisk of hemorrhage
2024
Endovascular arterial embolization versus conservative management with nasal packing alone for severe epistaxis: a nationwide cohort study
Chen H, Khunte M, Colasurdo M, Gunawardane S, Malhotra A, Gandhi D. Endovascular arterial embolization versus conservative management with nasal packing alone for severe epistaxis: a nationwide cohort study. Journal Of NeuroInterventional Surgery 2024, jnis-2024-022790. PMID: 39715667, DOI: 10.1136/jnis-2024-022790.Peer-Reviewed Original ResearchEndovascular arterial embolizationNasal packingSevere epistaxisPropensity score matchingNationwide Readmissions DatabaseArtery embolizationIschemic strokeCohort studyRates of patient morbidityHemorrhage risk factorsConservative management groupConservative managementRetrospective cohort studyNationwide cohort studyRate of ischemic strokeBalance patient characteristicsContemporary real-world dataAssociated with lower ratesPatients admitted to hospitalNon-routine dischargeRisk of ischemic strokeRecurrent epistaxisRecurrence ratePatient morbidityPatient characteristicsSubtyping strokes using blood‐based protein biomarkers: A high‐throughput proteomics and machine learning approach
Misra S, Singh P, Sengupta S, Kushwaha M, Rahman Z, Bhalla D, Talwar P, Nath M, Chakraborty R, Kumar P, Kumar A, Aggarwal P, Srivastava A, Pandit A, Mohania D, Prasad K, Mishra N, Vibha D. Subtyping strokes using blood‐based protein biomarkers: A high‐throughput proteomics and machine learning approach. European Journal Of Clinical Investigation 2024, 55: e14372. PMID: 39655799, DOI: 10.1111/eci.14372.Peer-Reviewed Original ResearchHigh-throughput proteomicsExpressed proteinsSWATH-MSInteraction networkPathway analysisProteomicsProtein biomarkersBlood-based protein biomarkersIntracerebral haemorrhageDifferentiate ISIschemic strokeProteinApo C1Clinical variablesDiscovery phaseMMP-9Multivariate logistic regression analysisLogistic regression analysisCut-off pointCytoscapeMobile Stroke Unit Management in Patients With Acute Ischemic Stroke Eligible for Intravenous Thrombolysis
Mac Grory B, Sun J, Alhanti B, Lusk J, Li F, Adeoye O, Furie K, Hasan D, Messe S, Sheth K, Schwamm L, Smith E, Bhatt D, Fonarow G, Saver J, Xian Y, Grotta J. Mobile Stroke Unit Management in Patients With Acute Ischemic Stroke Eligible for Intravenous Thrombolysis. JAMA Neurology 2024, 81: 1250-1262. PMID: 39466286, PMCID: PMC11581552, DOI: 10.1001/jamaneurol.2024.3659.Peer-Reviewed Original ResearchEmergency medical servicesEmergency medical service managementMobile stroke unitPrehospital managementSymptomatic intracranial hemorrhageHospital dischargeGlobal disabilityIn-hospital mortalityEfficacy end pointUtility-weighted modified Rankin scaleStroke unit managementAcute ischemic strokeIschemic strokePrimary analytic cohortDiagnosis of ischemic strokeIntravenous thrombolysisAmerican Heart AssociationEnd pointsGuidelines-StrokeUW-mRSSecondary efficacy end pointsMain OutcomesMedical servicesStroke unitAmbulation statusSex Differences in Tryptophan Metabolism via the Kynurenine Pathway in Acute Ischemic Stroke
Dylla L, Higgins H, Poisson S, Vu T, Reisz J, Herson P, Monte A. Sex Differences in Tryptophan Metabolism via the Kynurenine Pathway in Acute Ischemic Stroke. Clinical Therapeutics 2024, 46: 960-966. PMID: 39603869, PMCID: PMC11637908, DOI: 10.1016/j.clinthera.2024.10.015.Peer-Reviewed Original ResearchAcute ischemic strokeQuinolinic acid levelsLevels of tryptophanNIHSS scoreTryptophan metabolismMetabolite levelsKynurenine pathwayLinear regression modelsIncreased lifetime risk of strokeLifetime risk of strokeMass spectrometry-based metabolomicsPotential sex differencesDownstream kynurenine metabolitesAssociated with poor outcomesIschemic strokeKynurenine pathway metabolitesDecreased tryptophan concentrationsIncreased lifetime riskRegression modelsMultivariate linear regression modelSex differencesExperience worse outcomesRisk of strokeAcid levelsKynurenine metabolitesCare Quality and Outcomes of Ischemic Stroke in Patients With Premorbid Dementia: Get With The Guidelines-Stroke Registry
Ganesh A, Wang M, Schwamm L, Fonarow G, Messé S, Xian Y, Saver J, Smith E. Care Quality and Outcomes of Ischemic Stroke in Patients With Premorbid Dementia: Get With The Guidelines-Stroke Registry. Stroke 2024, 55: 2901-2905. PMID: 39503052, DOI: 10.1161/strokeaha.124.049027.Peer-Reviewed Original ResearchQuality of stroke carePremorbid dementiaGuidelines-Stroke registryStroke careGuidelines-StrokeDoor-to-needle timeImprove care qualityNational quality measuresQuality of careEmergency medical servicesQuality measuresHospice admissionPrestroke dementiaCare qualityDementia diagnosisIschemic strokeAcute stroke interventionHospital characteristicsIntravenous thrombolysisDischarge destinationPoststroke outcomesMedical servicesIn-hospital mortalityIschemic stroke patientsComprehensive stroke centerIs Clot Composition Associated With Cause of Stroke? A Systematic Review and Meta‐Analysis
Sujijantarat N, Templeton K, Antonios J, Renedo D, Koo A, Haynes J, Fathima B, Amllay A, Nowicki K, Huttner A, Giles J, Navaratnam D, Sansing L, Hebert R, King J, Matouk C. Is Clot Composition Associated With Cause of Stroke? A Systematic Review and Meta‐Analysis. Stroke Vascular And Interventional Neurology 2024, 4 DOI: 10.1161/svin.124.001426.Peer-Reviewed Original ResearchCause of strokeRed blood cellsWhite blood cellsBlood cellsMechanical thrombectomyCardioembolic groupHistological compositionMeta-analysisLow red blood cellQuantity of red blood cellsRandom-effects meta-analysisAcute ischemic strokeEffects meta-analysisEnglish-language articlesMean percentage differenceAdult patientsMEDLINE databaseCochrane LibraryClinical utilityIschemic strokeLanguage articlesPatientsPercentage differenceArteryCellular compositionTwenty Years of Sustained Improvement in Quality of Care and Outcomes for Patients Hospitalized With Stroke or Transient Ischemic Attack: Data From The Get With The Guidelines-Stroke Program
Xian Y, Li S, Jiang T, Beon C, Poudel R, Thomas K, Reeves M, Smith E, Saver J, Sheth K, Messé S, Schwamm L, Fonarow G. Twenty Years of Sustained Improvement in Quality of Care and Outcomes for Patients Hospitalized With Stroke or Transient Ischemic Attack: Data From The Get With The Guidelines-Stroke Program. Stroke 2024, 55: 2599-2610. PMID: 39429153, PMCID: PMC11518659, DOI: 10.1161/strokeaha.124.048174.Peer-Reviewed Original ResearchConceptsGuidelines-Stroke programEvidence-based stroke careDoor-to-needle timeTransient ischemic attackGuidelines-Stroke hospitalsEvidence-based careQuality of careSmoking cessation counselingSustained improvementQuality improvement initiativesSkilled nursing facilityIndependence of patientsAcute ischemic strokeIschemic strokeRelevant to patientsIschemic attackDoor-to-puncture timeCessation counselingGuidelines-StrokeAssociated with sustained improvementStroke careDysphagia screeningNursing facilitiesHospital characteristicsImprovement initiativesBenzodiazepine Utilization in Ischemic Stroke Survivors: Analyzing Initial Excess Supply and Longitudinal Trends
Torres V, Brooks J, Donahue M, Sun S, Hsu J, Price M, Blacker D, Schwamm L, Newhouse J, Haneuse S, Moura L. Benzodiazepine Utilization in Ischemic Stroke Survivors: Analyzing Initial Excess Supply and Longitudinal Trends. Stroke 2024, 55: 2694-2702. PMID: 39417222, PMCID: PMC11729356, DOI: 10.1161/strokeaha.124.047257.Peer-Reviewed Original ResearchConceptsIschemic stroke dischargesSkilled nursing facilityDays supplyMonths prior enrollmentUS Medicare claimsIschemic stroke survivorsPost-acute ischemic strokeIschemic strokeNursing facilitiesStroke survivorsStroke dischargesMedicare claimsBenzodiazepine initiationTraditional Medicare coverageMedicare coverageMedical insuranceBenzodiazepine prescriptionsExamined demographicsAcute ischemic strokeInitiation rateLongitudinal trendsPrescription patternsPart AHospital insurancePrescriptionNanotechnology approaches to drug delivery for the treatment of ischemic stroke
Peng B, Mohammed F, Tang X, Liu J, Sheth K, Zhou J. Nanotechnology approaches to drug delivery for the treatment of ischemic stroke. Bioactive Materials 2024, 43: 145-161. PMID: 39386225, PMCID: PMC11462157, DOI: 10.1016/j.bioactmat.2024.09.016.Peer-Reviewed Original ResearchBlood-brain barrierClinical translationClinical trialsFDA-approved pharmacotherapiesReview therapeutic agentsIschemic strokeTherapeutic agentsEffective treatment optionDrug deliveryTreatment of ischemic strokePotential clinical translationGlobal public health concernImprove delivery efficiencyTreatment optionsTreatment strategiesIschemic brainPublic health concernStroke pharmacotherapyEngineered nanoparticlesStroke treatment strategiesDelivery efficiencyNanotechnological approachesDrugPharmacotherapyStrokeIntravenous Thrombolysis in Patients With Cervical Artery Dissection
Shu L, Akpokiere F, Mandel D, Field T, Leon Guerrero C, Henninger N, Muppa J, Affan M, Haq Lodhi O, Heldner M, Antonenko K, Seiffge D, Arnold M, Salehi Omran S, Crandall R, Lester E, López-Mena D, Arauz A, Nehme A, Boulanger M, Touzé E, Sousa J, Sargento-Freitas J, Barata V, Castro-Chaves P, Brito M, Khan M, Mallick D, Rothstein A, Khazaal O, Kaufmann J, Engelter S, Traenka C, Aguiar de Sousa D, Soares M, Rosa S, Zhou L, Gandhi P, Mancini S, Metanis I, Leker R, Pan K, Dantu V, Baumgartner K, Burton T, Von Rennenberg R, Nolte C, Choi R, MacDonald J, Bavarsad Shahripour R, Guo X, Ghannam M, Almajali M, Samaniego E, Rioux B, Zine-Eddine F, Poppe A, Fonseca A, Baptista M, Cruz D, Romoli M, De Marco G, Longoni M, Keser Z, Griffin K, Kuohn L, Frontera J, Amar J, Giles J, Zedde M, Pascarella R, Grisendi I, Nzwalo H, Liebeskind D, Molaie A, Cavalier A, Kam W, Mac Grory B, Al Kasab S, Anadani M, Kicielinski K, Eltatawy A, Chervak L, Chulluncuy Rivas R, Aziz Y, Mistry E, Bakradze E, Tran T, Rodrigo-Gisbert M, Requena M, Saleh Velez F, Garcia J, Muddasani V, de Havenon A, Sanchez S, Vishnu V, Yaddanapudi S, Adams L, Browngoehl A, Ranasinghe T, Dunston R, Lynch Z, Penckofer M, Siegler J, Mayer S, Willey J, Zubair A, Cheng Y, Sharma R, Marto J, Krupka D, Klein P, Nguyen T, Asad S, Sarwat Z, Balabhadra A, Patel S, Secchi T, Martins S, Mantovani G, Kim Y, Krishnaiah B, Elangovan C, Lingam S, Qureshi A, Fridman S, Alvarado A, Khasiyev F, Linares G, Mannino M, Terruso V, Tountopoulou A, Tentolouris-Piperas V, Martinez-Marino M, Carrasco Wall V, Indraswari F, El Jamal S, Liu S, Zhou M, Alvi M, Ali F, Sarvath M, Morsi R, Kass-Hout T, Shi F, Zhang J, Sokhi D, Said J, Mongare N, Simpkins A, Gomez R, Sen S, Ghani M, Elnazeir M, Wangqin R, Xiao H, Kala N, Khan F, Stretz C, Mohammadzadeh N, Goldstein E, Furie K, Yaghi S. Intravenous Thrombolysis in Patients With Cervical Artery Dissection. Neurology 2024, 103: e209843. PMID: 39298709, PMCID: PMC11415265, DOI: 10.1212/wnl.0000000000209843.Peer-Reviewed Original ResearchConceptsAcute ischemic stroke symptomsCervical artery dissectionFunctional independenceIntravenous thrombolysisIschemic stroke symptomsStroke symptomsArtery dissectionIncidence of symptomatic intracranial hemorrhageIschemic strokeSymptomatic intracranial hemorrhageSuspected ischemic strokeClass III evidenceMedian ageSymptomatic ICHIntracranial hemorrhageSecondary analysisGuideline recommendationsICH riskIII evidenceFunctional outcomesPatientsThrombolysisCeADYoung adultsDissectionImpaired Peripheral Vascular Function Following Ischemic Stroke in Mice: Potential Insights into Blood Pressure Variations in the Post-Stroke Patient
Yilmaz G, Alexander J. Impaired Peripheral Vascular Function Following Ischemic Stroke in Mice: Potential Insights into Blood Pressure Variations in the Post-Stroke Patient. Pathophysiology 2024, 31: 488-501. PMID: 39311310, PMCID: PMC11417821, DOI: 10.3390/pathophysiology31030036.Peer-Reviewed Original ResearchIncreased blood pressure variabilityBlood pressure variabilityIschemic strokeAcetylcholine-induced endothelium-dependent vasodilationAssociated with poor clinical outcomesEndothelium-dependent vasodilator responsesPeripheral arteriesVascular smooth muscle toneResponse to SNPStroke animalsImpaired peripheral vascular functionPhenylephrine-induced vasoconstrictionEndothelium-dependent vasodilationPoor clinical outcomesSmooth muscle toneThoracic aortic segmentsDeterminants of blood pressurePressure variabilityPeripheral vascular functionPeripheral vascular responseWire myographyIsolated aortaVasoconstrictor responsesVasodilator responseRemote artery
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply