2025
Serotype specific pneumococcal vaccine effectiveness in children with sickle cell disease: A two-decade analysis
Zhang Z, Yildirim M, Keskinocak P, Dasthagirisaheb Y, Hinderstein S, Tran K, Crockett M, Burns M, Johnson H, Popstefanija M, Madoff L, Pelton S, Yildirim I. Serotype specific pneumococcal vaccine effectiveness in children with sickle cell disease: A two-decade analysis. Vaccine 2025, 56: 127193. PMID: 40318350, DOI: 10.1016/j.vaccine.2025.127193.Peer-Reviewed Original ResearchIncidence rate ratiosInvasive pneumococcal diseaseSickle cell diseaseIncidence ratePost-PCV13 periodCalculated incidence ratesValency vaccinesVaccine effectivenessPneumococcal diseaseHealthy childrenRates of invasive pneumococcal diseasePopulation-basedCell diseaseHealth conditionsRate ratiosNon-PCV13 serotypesPneumococcal vaccine effectivenessVulnerable populationsBootstrapping resamplingIncreased riskHigher IRNon-PCV13Genetic hematological diseasesHematological diseasesVaccine formulationsEffect of Peer Mentorship on Hospitalizations among Patients Receiving Maintenance Hemodialysis: A Pragmatic Randomized Controlled Trial.
Golestaneh L, Kim R, Roach C, Norris K, Fox A, Melamed M, Cavanaugh K. Effect of Peer Mentorship on Hospitalizations among Patients Receiving Maintenance Hemodialysis: A Pragmatic Randomized Controlled Trial. Journal Of The American Society Of Nephrology 2025 PMID: 40232855, DOI: 10.1681/asn.0000000709.Peer-Reviewed Original ResearchPatient participationPeer mentorshipUsual careEmergency departmentPragmatic randomized controlled trialPromote self-managementControlled trialsPrimary outcomePeer mentoring interventionTreat analysisIncidence rate ratiosEffects of peer mentoringCost of careRates of hospitalizationRandomized controlled trialsReduce hospitalization ratesSelf-managementIntervention periodED visitsTelephone contactTelephone callsRate ratiosHospitalization ratesPeer mentoringCareUsing Radiology as a Screening Tool to Identify Intimate Partner Violence
Lenehan P, Tang A, Watane G, Gujrathi R, Park H, Gosangi B, Thomas R, Franco F, Patel K, Warsofsky I, Rosner B, Khurana B. Using Radiology as a Screening Tool to Identify Intimate Partner Violence. Journal Of The American College Of Radiology 2025, 22: 395-404. PMID: 40044319, PMCID: PMC11887577, DOI: 10.1016/j.jacr.2025.01.003.Peer-Reviewed Original ResearchConceptsAdjusted incidence rate ratiosEmergency departmentRetrospective case-control studyImaging utilization patternsEvident injuriesCox proportional hazards regressionRace-matched controlsCase-control studyTime-to-event analysisProportional hazards regressionImaging utilizationIncidence rate ratiosCumulative incidenceAnatomical sitesScreening mammogramsHazards regressionOdds ratioImaging studiesIntimate partner violencePatientsInjury patternsLogistic regressionInjuryOrgan systemsPoisson regressionIncomplete Ascertainment of Mortality in a Nationally Representative Longitudinal Study of Community-Living Older Americans
Gill T, Liang J, Vander Wyk B, Leo-Summers L, Wang Y, Becher R, Davis-Plourde K. Incomplete Ascertainment of Mortality in a Nationally Representative Longitudinal Study of Community-Living Older Americans. The Journals Of Gerontology Series A 2025, glaf014. PMID: 39823281, DOI: 10.1093/gerona/glaf014.Peer-Reviewed Original ResearchNational Health and Aging Trends StudyAscertainment of mortalityIncomplete ascertainmentLongitudinal studies of older personsStudy of older personsNationally representative longitudinal studyIncidence rate ratiosLoss to follow-upMortality incidence ratesYear of deathLongitudinal studyRepresentative longitudinal studyCommunity-livingTrends StudyOlder personsRecommended strategiesMedicare dataRate ratiosCumulative mortality rateIncidence rateResults of longitudinal analysesAscertainmentEvaluate mortalityLongitudinal analysisDecedents
2024
Occurrence of Opioid-Related Neurocognitive Symptoms Associated With Long-term Opioid Therapy
León C, Sung M, Reisman J, Liu W, Kerns R, Gordon K, Mitra A, Kwon S, Yu H, Becker W, Li W. Occurrence of Opioid-Related Neurocognitive Symptoms Associated With Long-term Opioid Therapy. The Clinical Journal Of Pain 2024, 41: e1266. PMID: 39682036, PMCID: PMC11729567, DOI: 10.1097/ajp.0000000000001266.Peer-Reviewed Original ResearchLong-term opioid therapyElectronic health recordsIncidence rate ratiosOpioid-related harmsSubstance use disordersNeurocognitive symptomsHazard ratioPatients prescribed long-term opioid therapyVeterans Health AdministrationCalculated incidence ratesAssociated with increased likelihoodChronic obstructive pulmonary diseasePost-traumatic stress disorderHealth recordsProportional hazards modelRetrospective cohort studyObstructive pulmonary diseaseHealth AdministrationRate ratiosIncidence rateCohort studyTraumatic brain injuryClinical notesExtract dataHazards modelSex, Race and Geographic Disparities in Early Age at Onset Hematologic Malignancies
Sklarz T, DuBois T, Lynch S. Sex, Race and Geographic Disparities in Early Age at Onset Hematologic Malignancies. Blood 2024, 144: 5117. DOI: 10.1182/blood-2024-207878.Peer-Reviewed Original ResearchNon-Hispanic blacksIncidence rate ratiosNon-Hispanic whitesNon-Hispanic Black individualsLate-onset diseaseNational Program of Cancer RegistriesNon-Hispanic Asian/Pacific IslanderPrevention effortsRelative riskNon-Hispanic white populationPrecision public healthPublic health approachSurveillance dataOnset diseaseEarly-onset cancersHigh-burden statesPopulation-level surveillance dataNon-Hodgkin's lymphomaHighest incidence rateHematologic malignanciesHigher relative riskScreening interventionsCancer RegistryRacial/ethnic subpopulationsNon-Hispanic5-year vaccine protection following a single dose of Vi-tetanus toxoid conjugate vaccine in Bangladeshi children (TyVOID): a cluster randomised trial
Qadri F, Khanam F, Zhang Y, Biswas P, Voysey M, Mujadidi Y, Kelly S, Bhuiyan A, Rajib N, Hossen I, Rahman N, Islam S, Pitzer V, Kim Y, Clemens J, Pollard A, Liu X. 5-year vaccine protection following a single dose of Vi-tetanus toxoid conjugate vaccine in Bangladeshi children (TyVOID): a cluster randomised trial. The Lancet 2024, 404: 1419-1429. PMID: 39396349, DOI: 10.1016/s0140-6736(24)01494-6.Peer-Reviewed Original ResearchConceptsTyphoid conjugate vaccineJapanese encephalitis vaccineVaccine effectivenessRandomised controlled trialsConjugate vaccineFollow-upTyphoid feverControlled trialsVaccine protectionChildren aged 9 monthsIncreased risk of typhoid feverAnti-Vi IgGRisk of typhoid feverVaccine efficacy dataTest-negative designAged 9 monthsUnvaccinated individualsHigh-burden countriesIncidence rate ratiosAnalyses of vaccine effectivenessSingle-doseSingle doseDecay of antibodiesSubgroup analysisBooster doseLeveraging real-world data from administrative claims and medical records to inform safety and effectiveness of piperacillin-tazobactam in the management of pediatric hospital–acquired pneumonia
Blumenstock J, Faerber J, Menon M, Lawler R, Downes K, Kratz E, Erickson K, Haltzman-Cassenti B, Yildirim I, Hussaini L, Elmontser M, Sederdahl B, Hahn A, Thomson J, Newland J, Terrill C, Bradley J, Zachariah P, Younus M, Mo J, Wible M, Tawadrous M, Fisher B. Leveraging real-world data from administrative claims and medical records to inform safety and effectiveness of piperacillin-tazobactam in the management of pediatric hospital–acquired pneumonia. American Journal Of Epidemiology 2024, kwae251. PMID: 39108170, DOI: 10.1093/aje/kwae251.Peer-Reviewed Original ResearchIncidence rate ratiosPediatric Health Information SystemHospital-acquired pneumoniaMedical recordsHealth information systemsPoisson regression modelsBetween-group differencesStudy combined dataEffects of medicationAdministrative claimsRate ratiosClinical improvementSecondary outcomesBetween-groupEffect of piperacillin-tazobactamComparative riskReal World DataHospital acquired pneumoniaRegression modelsTreating hospital-acquired pneumoniaOff-label settingCIPediatric institutionControlled studiesPiperacillin-tazobactamDisparities in Tuberculosis Incidence by Race and Ethnicity Among the U.S.-Born Population in the United States, 2011 to 2021 : An Analysis of National Disease Registry Data.
Li Y, Regan M, Swartwood N, Barham T, Beeler Asay G, Cohen T, Hill A, Horsburgh C, Khan A, Marks S, Myles R, Salomon J, Self J, Menzies N. Disparities in Tuberculosis Incidence by Race and Ethnicity Among the U.S.-Born Population in the United States, 2011 to 2021 : An Analysis of National Disease Registry Data. Annals Of Internal Medicine 2024, 177: 418-427. PMID: 38560914, PMCID: PMC11770560, DOI: 10.7326/m23-2975.Peer-Reviewed Original ResearchConceptsIncidence rate ratiosNon-Hispanic white personsTB incidence rateRate ratiosIncidence rateTB incidenceSocial determinants of healthRelated disparitiesWhite personsHealth equity goalsU.S.-born populationAbsolute disparityDeterminants of healthTB registry dataRacial/ethnic minority populationsCenters for Disease Control and PreventionDisease Control and PreventionIncidence rate differenceTB casesYoung personControl and PreventionState of residenceAI/AN personsSocial determinantsRacial/ethnic disparitiesBreast cancer incidence trends in Golestan, Iran: An age-period-cohort analysis by ethnic region, 2004-2018
Ghasemi-Kebria F, Fazel A, Semnani S, Etemadi A, Naeimi-Tabiei M, Hasanpour-Heidari S, Salamat F, Jafari-Delouie N, Sedaghat S, Sadeghzadeh H, Akbari M, Mehrjerdian M, Weiderpass E, Roshandel G, Bray F, Malekzadeh R. Breast cancer incidence trends in Golestan, Iran: An age-period-cohort analysis by ethnic region, 2004-2018. Cancer Epidemiology 2024, 89: 102525. PMID: 38228040, DOI: 10.1016/j.canep.2024.102525.Peer-Reviewed Original ResearchAge-standardized incidence rateAge-period-cohortIncidence rate ratiosAge-period-cohort analysisIncidence trendsCalculated age-standardized incidence ratesBreast cancer incidence trendsTrends of breast cancerCohort effectsNon-linear cohort effectsIncidence rateFemale breast cancer casesCancer incidence trendsBreast cancer incidenceAnnual percentage changeIncreased IRRsRural areasBreast cancer casesBreast cancerCancer incidenceDiagnosis yearReproductive factorsBirth cohortCancer casesRate ratiosLong-term surveillance of invasive pneumococcal disease: The impact of 10-valent pneumococcal conjugate vaccine in the metropolitan region of Salvador, Brazil
Reis J, Azevedo J, de Oliveira A, de Oliveira Menezes A, Pedrosa M, dos Santos M, Ribeiro L, de Freitas H, Gouveia E, Teles M, da Glória Carvalho M, Reis M, Nascimento-Carvalho C, Verani J. Long-term surveillance of invasive pneumococcal disease: The impact of 10-valent pneumococcal conjugate vaccine in the metropolitan region of Salvador, Brazil. Vaccine 2024, 42: 591-597. PMID: 38184393, PMCID: PMC10872423, DOI: 10.1016/j.vaccine.2023.12.055.Peer-Reviewed Original ResearchConceptsIncidence rate ratiosInvasive pneumococcal diseaseLower-middle-income settingsPCV10 introductionInvasive pneumococcal disease incidenceProspective laboratory-based surveillanceNational infant immunization programsPre-PCV10 periodNon-vaccine serotypesRate ratiosInfant immunization programIncidence ratePneumococcal conjugate vaccineLaboratory-based surveillanceIPD incidenceImpact of PCV10Multiplex polymerase chain reactionMetropolitan region of SalvadorCompare ratesPCV10 serotypesLong-term impactSterile sitesQuellung reactionSerotype 15BVaccine-type
2023
INTERRUPTED TIME SERIES ANALYSIS OF THE 2015 DUTCH LONG-TERM CARE: ACUTE HOSPITAL UTILIZATION OF OLDER ADULTS
Wammes J, Bakx P, Wouterse B, Buurman B, Murphy T, Vroomen J. INTERRUPTED TIME SERIES ANALYSIS OF THE 2015 DUTCH LONG-TERM CARE: ACUTE HOSPITAL UTILIZATION OF OLDER ADULTS. Innovation In Aging 2023, 7: 693-693. PMCID: PMC10738593, DOI: 10.1093/geroni/igad104.2250.Peer-Reviewed Original ResearchIncidence rate ratiosLong-term careAcute hospitalsOlder adultsRates of acute hospitalizationCalculate adjusted incidence rate ratiosProportion of older adultsIncreasing proportion of older adultsAdjusted incidence rate ratiosInterrupted time series designAcute hospital utilizationNational hospital dataPromote older adultsInterrupted time series analysisPost-reform periodTime series designAge-in-placeHospital utilizationHospital dataRate ratiosSeries designAverage hospital lengthHospitalization ratesPositive changesHospital1313. Determinants of Prosthetic Joint Infection According to Time Following Total Knee Arthroplasty: A Retrospective Cohort Study Among US Veterans
Weinstein E, Re V, Stephens-Shields A, Newcomb C, Silibovsky R, Nelson C, O’Donnell J, Glaser L, Hsieh E, Hanberg J, Akgün K, Tate J, King J. 1313. Determinants of Prosthetic Joint Infection According to Time Following Total Knee Arthroplasty: A Retrospective Cohort Study Among US Veterans. Open Forum Infectious Diseases 2023, 10: ofad500.1152. PMCID: PMC10679182, DOI: 10.1093/ofid/ofad500.1152.Peer-Reviewed Original ResearchPrimary total knee arthroplastyProsthetic joint infectionIncidence rate ratiosTotal knee arthroplastyAutoimmune inflammatory arthritisYear of TKAEarly prosthetic joint infectionLate prosthetic joint infectionsVA Surgical Quality Improvement ProgramPeri-operative factorsVeterans Health AdministrationJoint infectionKnee arthroplastyHCV infectionInflammatory arthritisAlcohol use disorderOperative timeRate ratioUse disordersElective primary total knee arthroplastySurgical Quality Improvement ProgramSkin/soft tissueRetrospective cohort studyConfidence intervalsQuality Improvement Program2466. The Evolution of Candidemia during the COVID-19 Pandemic in Connecticut
Gleason-Vergados J, Correa M, Meek J, Banach D. 2466. The Evolution of Candidemia during the COVID-19 Pandemic in Connecticut. Open Forum Infectious Diseases 2023, 10: ofad500.2084. PMCID: PMC10677364, DOI: 10.1093/ofid/ofad500.2084.Peer-Reviewed Original ResearchIncidence rate ratiosIncidence rateCandidemia casesCOVID-19 pandemicNon-white race/ethnicityHospital-onset infectionsEpidemiology of candidemiaRate of candidemiaCOVID-19 treatmentCOVID-19 surgeFuture public health crisesLife-threatening bloodstream infectionsDifferent incidence ratesCOVID-19 case numbersRace/ethnicityCandidemia ratesClinical characteristicsPatient demographicsPublic health crisisInitial surgeMechanical ventilationBloodstream infectionsChi-square analysisCandidemia epidemiologyCandidemia1312. Incidence and Microbiology of Prosthetic Joint Infection According to Time Following Total Knee Arthroplasty: A Retrospective Cohort Study Among US Veterans
Weinstein E, Re V, Stephens-Shields A, Newcomb C, Silibovsky R, Nelson C, O’Donnell J, Glaser L, Hsieh E, Hanberg J, Akgün K, Tate J, King J. 1312. Incidence and Microbiology of Prosthetic Joint Infection According to Time Following Total Knee Arthroplasty: A Retrospective Cohort Study Among US Veterans. Open Forum Infectious Diseases 2023, 10: ofad500.1151. PMCID: PMC10678406, DOI: 10.1093/ofid/ofad500.1151.Peer-Reviewed Original ResearchLate prosthetic joint infectionsPrimary total knee arthroplastyProsthetic joint infectionTotal knee arthroplastyIncidence rate ratiosElective primary total knee arthroplastyJoint infectionKnee arthroplastyIncidence rateChi-squared testGram-negative organismsCumulative incidenceConfidence intervalsIncidence of PJIMicrobiology dataEarly prosthetic joint infectionKaplan-Meier failure curvesCulture-negative prosthetic joint infectionPrimary TKA surgeryRetrospective cohort studyKaplan-Meier methodPearson's chi-squared testGrant/research supportOverall study periodIncident hospitalizationPneumococcal Infections in Children with Sickle Cell Disease Before and After Pneumococcal Conjugate Vaccines
Adamkiewicz T, Yee M, Thomas S, Tunali A, Lai K, Omole F, Lane P, Yildirim I. Pneumococcal Infections in Children with Sickle Cell Disease Before and After Pneumococcal Conjugate Vaccines. Blood Advances 2023, 7: 6751-6761. PMID: 37698500, PMCID: PMC10660014, DOI: 10.1182/bloodadvances.2022009643.Peer-Reviewed Original ResearchConceptsInvasive pneumococcal diseaseSickle cell diseaseCell diseasePCV13-serotype invasive pneumococcal diseaseSerotype invasive pneumococcal diseaseNon-PCV13 serotypesPneumococcal polysaccharide vaccinePneumococcal conjugate vaccineIncidence rate ratiosYears of vaccinationReference populationLife-threatening risksIPD episodesIPD serotypesPneumococcal diseasePneumococcal infectionPolysaccharide vaccineConjugate vaccineHemoglobin SSVaccine licensureEffective vaccinePenicillin resistanceDisease controlVaccineAfrican American childrenIncidence of Lung Adenocarcinoma by Age, Sex, and Smoking Status in Taiwan
Chien L, Jiang H, Tsai F, Chang H, Freedman N, Rothman N, Lan Q, Hsiung C, Chang I. Incidence of Lung Adenocarcinoma by Age, Sex, and Smoking Status in Taiwan. JAMA Network Open 2023, 6: e2340704. PMID: 37910104, PMCID: PMC10620613, DOI: 10.1001/jamanetworkopen.2023.40704.Peer-Reviewed Original ResearchConceptsNational Health Insurance Research DatabaseTaiwan Cancer RegistryNational Health Interview SurveyLung ADCSmoking statusIncidence rate ratiosHealth Interview SurveyTumor stageRisk factorsCohort studyIncidence rateMAIN OUTCOMEHigher ageLung cancer prevention strategiesMale incidence rate ratiosPopulation-based cohort studyTaiwan National Health Interview SurveyHealth Insurance Research DatabaseLung adenocarcinoma incidenceInterview SurveyCancer prevention strategiesEffect of smokingInvasive lung cancerCancer-free individualsHigh tobacco useIncidence, Microbiological Studies, and Factors Associated With Prosthetic Joint Infection After Total Knee Arthroplasty
Weinstein E, Stephens-Shields A, Newcomb C, Silibovsky R, Nelson C, O’Donnell J, Glaser L, Hsieh E, Hanberg J, Tate J, Akgün K, King J, Re V. Incidence, Microbiological Studies, and Factors Associated With Prosthetic Joint Infection After Total Knee Arthroplasty. JAMA Network Open 2023, 6: e2340457. PMID: 37906194, PMCID: PMC10618849, DOI: 10.1001/jamanetworkopen.2023.40457.Peer-Reviewed Original ResearchConceptsPrimary total knee arthroplastyProsthetic joint infectionTotal knee arthroplastyIncidence rate ratiosLate prosthetic joint infectionsPostoperative periodIncidence rateCohort studyOverall cohortJoint infectionKnee arthroplastyVeterans Affairs Surgical Quality Improvement Program dataElective primary total knee arthroplastyEarly prosthetic joint infectionHepatitis C virus infectionQuality Improvement Program dataVeterans Affairs Corporate Data WarehouseAutoimmune inflammatory arthritisPostoperative antibiotic useC virus infectionRisk factor modificationChronic kidney diseasePeripheral artery diseaseLate postoperative periodYears of careThe effect of duration of untreated psychosis (DUP) on the risk for hospitalization after admission to a first episode service
Ferrara M, Guloksuz S, Hazan H, Li F, Tek C, Sykes L, Riley S, Keshavan M, Srihari V. The effect of duration of untreated psychosis (DUP) on the risk for hospitalization after admission to a first episode service. Schizophrenia Research 2023, 260: 198-204. PMID: 37688984, DOI: 10.1016/j.schres.2023.08.005.Peer-Reviewed Original ResearchConceptsFirst-episode psychosis servicesLength of stayUntreated psychosisPsychiatric hospitalizationFirst-episode servicesDuration of hospitalizationIncidence rate ratiosNon-affective psychosisNew Haven areaPoisson regression modelsPatient characteristicsHospitalization ratesRecent onsetMedical recordsHospitalizationEffect of durationNegative binomial regressionSpecialized treatmentPsychosisRate ratioBinomial regressionAdmissionDUPEnrollmentFirst yearCOVID-19 Severity and Waning Immunity After up to 4 mRNA Vaccine Doses in 73 608 Patients With Cancer and 621 475 Matched Controls in Singapore
Tan W, Tan J, Lim J, Tan R, Bin Lee A, Leong F, Lee S, Chai L, Tan T, Bin Abdul Malek M, Ong B, Lye D, Chiew C, Chng W, Lim S, Bharwani L, Tan I, Sundar R, Tan K. COVID-19 Severity and Waning Immunity After up to 4 mRNA Vaccine Doses in 73 608 Patients With Cancer and 621 475 Matched Controls in Singapore. JAMA Oncology 2023, 9: 1221-1229. PMID: 37440245, PMCID: PMC10346511, DOI: 10.1001/jamaoncol.2023.2271.Peer-Reviewed Original ResearchConceptsIncidence rate ratiosCancer survivorsVaccine doseSevere diseaseCohort studyTreated patientsProspective multicenter observational cohort studyCompeting-risk regression analysisMulticenter observational cohort studyMatched controlsVaccine efficacyVaccine effectivenessRisk of poor outcomesWaning of vaccine effectivenessSevere COVID-19 disease outcomesMRNA vaccine doseRisk of deathObservational cohort studyMRNA-based vaccinesSocioeconomic statusSARS-CoV-2 DeltaRate ratiosCOVID-19 hospitalizationIncidence rateOmicron wave
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply