2025
I Brazilian guideline on hypertension in dialysis of the Brazilian Society of Nephrology
Rodrigues C, Ferreira-Filho S, de Souza Moura A, Poli-de-Figueiredo C, da Silva D, Polacchini F, de Almeida F, Pinheiro M, Bezerra R, de Paula R, Peixoto A, Figueiredo A, Feitosa A, Machado C, Amodeo C, Mion D, Muxfeldt E, da Silva G, Moura-Neto J, Pazeli J, Lotaif L, Drager L, Martín L, Bortolotto L, Bastos M, Malachias M, Moreira M, Canziani M, Miranda R, da Silva Franco R, Pecoits R, Mulinari R, Elias R, Barroso W, Nadruz W. I Brazilian guideline on hypertension in dialysis of the Brazilian Society of Nephrology. Brazilian Journal Of Nephrology 2025, 47: e20240033. PMID: 40009791, PMCID: PMC11864789, DOI: 10.1590/2175-8239-jbn-2024-0033en.Peer-Reviewed Original ResearchConceptsBrazilian Society of NephrologyPeritoneal dialysisSociety of NephrologyBlood pressureRecommended blood pressureDepartment of HypertensionBlood pressure targetsNon-pharmacological treatmentContext of hemodialysisAntihypertensive drugsLifestyle changesReduce morbidityAntihypertensive medicationsDialysis patientsPressure targetsDialysis settingBrazilian guidelinesHypertensionDialysis centersComplementary assessmentPatientsBP measurementsDialysisNephrology practiceCardiovascular onesRenalase levels are decreased in maternal blood and placental tissues in pregnancies associated with preterm preeclampsia
Soliman Y, Eke C, Guo X, Wang M, Silva T, Désir G, Konnikova L. Renalase levels are decreased in maternal blood and placental tissues in pregnancies associated with preterm preeclampsia. Scientific Reports 2025, 15: 6480. PMID: 39987333, PMCID: PMC11846959, DOI: 10.1038/s41598-025-90524-z.Peer-Reviewed Original ResearchConceptsCases of preeclampsiaSerum renalasePreterm casesRenalase levelsPregnancies associated with hypertensionFactors associated with preeclampsiaRisk of eclampsiaPathophysiology of preeclampsiaLevels of renalasePreterm preeclampsiaTerm preeclampsiaMaternal serumMaternal bloodRenalase expressionPlacental villiPreeclampsiaPlacental tissuePretermPlacentaRenalaseMaternal healthPregnancyHypertensionSerumVariable effectsExercise Pulmonary Hypertension and Beyond: Insights in Exercise Pathophysiology in Pulmonary Arterial Hypertension (PAH) from Invasive Cardiopulmonary Exercise Testing
Tarras E, Singh I, Kreiger J, Joseph P. Exercise Pulmonary Hypertension and Beyond: Insights in Exercise Pathophysiology in Pulmonary Arterial Hypertension (PAH) from Invasive Cardiopulmonary Exercise Testing. Journal Of Clinical Medicine 2025, 14: 804. PMID: 39941482, PMCID: PMC11818252, DOI: 10.3390/jcm14030804.Peer-Reviewed Original ResearchInvasive cardiopulmonary exercise testingPulmonary arterial hypertensionCardiopulmonary exercise testingArterial hypertensionAssociated with pulmonary vascular remodelingExercise testRight heart failureExercise pulmonary hypertensionPulmonary vascular remodelingPulmonary hypertensionProgressive diseasePulmonary vasculatureTherapeutic optionsExercise pathophysiologyHigh morbidityHeart failureEarly diagnosisVascular remodelingTherapeutic approachesPersonalized treatmentHypertensionDisease subtypesDiagnosisSkeletal muscleDiseaseMeasurement of Blood Pressure in Children and Adolescents Outside the Office for the Diagnosis of Hypertension
Nugent J. Measurement of Blood Pressure in Children and Adolescents Outside the Office for the Diagnosis of Hypertension. Current Cardiology Reports 2025, 27: 27. PMID: 39826056, DOI: 10.1007/s11886-024-02178-4.Peer-Reviewed Original ResearchConceptsAmbulatory blood pressure monitoringBlood pressure monitoringHome blood pressure monitoringDiagnosis of hypertensionBlood pressurePressure monitoringUsefulness of ambulatory blood pressure monitoringOffice blood pressureOut-of-office blood pressure measurementsTarget organ damageNovel care pathwayHome blood pressureMeasurement of blood pressureBlood pressure measurementsOrgan damageHypertensionHypertension statusSubspecialty settingsCare pathwaysDiagnosis
2024
Renovascular hypertension – a primer for the radiologist
Dixe de Oliveira Santo I, Sindoni J, Czeyda-Pommersheim F, Solomon N, Sailer A, Bhatt S, Fananapazir G, Pellerito J, Revzin M. Renovascular hypertension – a primer for the radiologist. Abdominal Radiology 2024, 1-13. PMID: 39542950, DOI: 10.1007/s00261-024-04677-y.Peer-Reviewed Original ResearchRenovascular hypertensionRenal arteryCause of renovascular hypertensionComputed tomography angiographyMagnetic resonance angiographyDiagnosing RVHExtrinsic compressionSecondary hypertensionRare conditionImaging findingsPolyarteritis nodosaSurgical interventionFibromuscular dysplasiaAnatomical variantsPage kidneyPictorial reviewHypertension casesAccurate diagnosisMedical managementDiagnostic criteriaTreatment approachesImaging modalitiesHypertensionImpact diagnosisYoung femalesMOGAD presenting as fulminant intracranial hypertension
Nagaratnam S, Gill A, Jeyakumar N, Xi S, Lin M, Martin A, Varikatt W, Fong M, Morales-Briceno H. MOGAD presenting as fulminant intracranial hypertension. Journal Of Neuroimmunology 2024, 397: 578487. PMID: 39547117, DOI: 10.1016/j.jneuroim.2024.578487.Peer-Reviewed Original ResearchMyelin oligodendrocyte glycoprotein antibody diseaseSevere intracranial hypertensionIntracranial hypertensionFulminant intracranial hypertensionAbsence of demyelinationBrain CT scanManagement of intracranial pressureImmunosuppressive therapyMOG antibodiesBiopsy resultsCortical encephalitisIntensive immunotherapyAntibody diseaseBrainstem encephalitisAntibody positivityClinical improvementSurgical managementNormal MRIBrain biopsyClinical featuresCT scanDifferential diagnosisHypertensionIntracranial pressureSubcortical demyelinationHome is where the right ventricle lives: bronchopulmonary dysplasia-associated pulmonary hypertension and home ventilation
Gentle S, Ambalavanan N. Home is where the right ventricle lives: bronchopulmonary dysplasia-associated pulmonary hypertension and home ventilation. Pediatric Research 2024, 97: 31-32. PMID: 39266628, PMCID: PMC11798836, DOI: 10.1038/s41390-024-03550-4.Peer-Reviewed Original ResearchSex Differences in Hypertension and Its Management Throughout Life
Yeo W, Abraham R, Surapaneni A, Schlosser P, Ballew S, Ozkan B, Flaherty C, Yu B, Bonventre J, Parikh C, Kimmel P, Vasan R, Coresh J, Grams M. Sex Differences in Hypertension and Its Management Throughout Life. Hypertension 2024, 81: 2263-2274. PMID: 39229711, PMCID: PMC11483212, DOI: 10.1161/hypertensionaha.124.22980.Peer-Reviewed Original ResearchPrevalence of hypertensionUncontrolled hypertensionChronic kidney disease progressionPrevalence of uncontrolled hypertensionKidney disease progressionBody mass indexClasses of medicationsSex differencesEstimate sex differencesCoronary heart diseaseHeart failureMass indexAntihypertensive medicationsDisease progressionStudy visitsAtherosclerosis RiskHypertensionHigh riskHypertensive individualsHeart diseaseLife courseCommunity studiesPrevalenceMedicationA Curriculum on Advanced Topics in Hypertension for Internal Medicine Residents
Gallagher B, Windish D. A Curriculum on Advanced Topics in Hypertension for Internal Medicine Residents. Southern Medical Journal 2024, 117: 556-561. PMID: 39227050, DOI: 10.14423/smj.0000000000001732.Peer-Reviewed Original ResearchInternal medicine residentsMedicine residentsRepeated-measures analysis of varianceChronic kidney diseaseSmall group sessionsRepeated-measures analysisMean confidence scoreHypertensive urgencySecondary hypertensionKidney diseaseHypertensionUS adultsImmediate postMulti-institutional surveyResident confidenceHypertension expertsPostcurriculum surveysOutpatient settingPostcurriculumPrecurriculumHalf-dayTime pointsWeeksTraining scoresAnalysis of varianceStructural bases for Na+-Cl− cotransporter inhibition by thiazide diuretic drugs and activation by kinases
Zhao Y, Schubert H, Blakely A, Forbush B, Smith M, Rinehart J, Cao E. Structural bases for Na+-Cl− cotransporter inhibition by thiazide diuretic drugs and activation by kinases. Nature Communications 2024, 15: 7006. PMID: 39143061, PMCID: PMC11324901, DOI: 10.1038/s41467-024-51381-y.Peer-Reviewed Original ResearchConceptsNa+-Cl- cotransporterFamilial hyperkalemic hypertensionRenal salt retentionThiazide diuretic drugsNa+-Cl-Cotransporter inhibitionNCC activitySalt reabsorptionDiuretic drugsBlood pressureBalanced electrolyteTreat hypertensionIon translocation pathwayIon translocationThiazideHypertensionSalt retentionOrthosteric siteCo-structureCarboxyl-terminal domainKinase cascadeEdemaChlorthalidoneCotransporterTranslocationBlood pressure changes during ketamine infusion for the treatment of depression
Ansari M, Pittman B, Tylee D, Ostroff R, Wilkinson S, Nikayin S. Blood pressure changes during ketamine infusion for the treatment of depression. General Hospital Psychiatry 2024, 90: 62-67. PMID: 38991311, DOI: 10.1016/j.genhosppsych.2024.07.001.Peer-Reviewed Original ResearchKetamine infusionBlood pressure changesBlood pressureRetrospective chart review of patientsChart review of patientsMedical history of hypertensionRetrospective chart reviewHistory of hypertensionSignificant blood pressureDiastolic blood pressureTreatment of depressionSevere hypertensionPatient demographicsHypertensive patientsInfusion sessionsMedical historyHypertensive eventsInfusionPatientsKetamineBP surgeCardiovascular monitoringBloodHypertensionPressure changesAchieved oxygen saturations and risk for bronchopulmonary dysplasia with pulmonary hypertension in preterm infants
Gentle S, Singh A, Travers C, Nakhmani A, Carlo W, Ambalavanan N. Achieved oxygen saturations and risk for bronchopulmonary dysplasia with pulmonary hypertension in preterm infants. Archives Of Disease In Childhood 2024, 109: 941-947. PMID: 38937062, PMCID: PMC11503043, DOI: 10.1136/archdischild-2024-327014.Peer-Reviewed Original ResearchConceptsBronchopulmonary dysplasia-associated pulmonary hypertensionOxygen saturation indexSurvival statusPreterm infantsPulmonary hypertensionHigher FiOLt;29 weeks' gestationFraction of inspired oxygenWeeks postmenstrual ageSingle-centre studyNon-invasive predictorCase-control studyPostmenstrual ageWeeks gestationBronchopulmonary dysplasiaRespiratory supportNon-survivorsInfantsOxygen saturationPatient outcomesPretermSurvivalHypertensionWeeksPredictorsHeat exposure induced risks of preterm birth mediated by maternal hypertension
Wang L, Di J, Wang Q, Zhang H, Zhao W, Shi X, Di Q, Ji J, Liang W, Huang C. Heat exposure induced risks of preterm birth mediated by maternal hypertension. Nature Medicine 2024, 30: 1974-1981. PMID: 38750350, DOI: 10.1038/s41591-024-03002-w.Peer-Reviewed Original ResearchRisk of maternal hypertensionRisk of preterm birthMaternal hypertensionPreterm birthClinical subtypes of preterm birthIncreased risk of preterm birthSubtypes of preterm birthIncidence of preterm birthBlood pressureMaternal blood pressureSingleton live birthsElevated blood pressureGestational weeksLarge-population studiesEarly pregnancyLive birthsClinical subtypesCohort studyIncreased riskHypertensionBirthMediation analysisEffects of heat exposureHeat exposureExposureImpact of jugular vein ligation on cerebrospinal fluid clearance from G-lymphatic system in mice
Ruze A, Mouton L, Singhabahu R, Gottschalk J, Spajer M, Thomas J, Lenck S, Santin M. Impact of jugular vein ligation on cerebrospinal fluid clearance from G-lymphatic system in mice. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2024 DOI: 10.58530/2024/1185.Peer-Reviewed Original ResearchJugular vein ligationVein ligationBilateral jugular vein ligationVenous outflow abnormalitiesCerebrospinal fluid clearanceCerebral blood flowFluid clearanceOutflow abnormalitiesLymphatic perfusionPost-surgeryLymphatic flowFluid homeostasisBrain volumetryBlood flowMiceCerebrovascular changesNeurological disordersLigationProgressive alterationBrainBaselineSystem's roleHypertensionAbnormalitiesCNSTumoral Pulmonary Hypertension in a Patient With Metastatic Breast Cancer: Diagnostic Opportunity of the Right Heart Catheterization
Tarras E, Sen S, Wang H, Singh I. Tumoral Pulmonary Hypertension in a Patient With Metastatic Breast Cancer: Diagnostic Opportunity of the Right Heart Catheterization. 2024, a2208-a2208. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a2208.Peer-Reviewed Original ResearchCellular Mechanisms Underlying the Pathogenetic Role of the Primary Cilium in Pulmonary Arterial Hypertension
Melnikov A, Solymosi P, Pennitz P, Schupp J, Nouailles G, Perret P, Gallo K, Hegemann N, Nambiar Veetil N, Klepetko W, Sinn K, Erfinanda L, Simmons S, Kucherenko M, Knosalla C, Preissner R, Kwapiszewska G, Witzenrath M, Kuebler W. Cellular Mechanisms Underlying the Pathogenetic Role of the Primary Cilium in Pulmonary Arterial Hypertension. 2024, a6790-a6790. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a6790.Peer-Reviewed Original ResearchRecurrence of Pulmonary Arteriovenous Malformation after Embolization in Patients with Pulmonary Hypertension
Fish A, Wang D, Knight E, Pollak J, Schlachter T. Recurrence of Pulmonary Arteriovenous Malformation after Embolization in Patients with Pulmonary Hypertension. Journal Of Vascular And Interventional Radiology 2024, 35: 1148-1153. PMID: 38692392, DOI: 10.1016/j.jvir.2024.04.017.Peer-Reviewed Original ResearchPulmonary arteriovenous malformationsPulmonary hypertensionArteriovenous malformationsRecurrence of pulmonary arteriovenous malformationsFollow-upChest CT follow-upPresence of pulmonary hypertensionCT follow-upShorter surveillance intervalsPulmonary artery pressureHistory of smokingPresence of PHCuracao criteriaSurveillance intervalsSmoking historyArterial pressureMultivariate analysisRecurrenceGenetic testingOdds ratioHypertensionPatientsStratified analysisGeneral demographicsStudy periodA central arteriovenous fistula reduces systemic hypertension in a mouse model
Brahmandam A, Alves R, Liu H, Gonzalez L, Aoyagi Y, Ohashi Y, Langford J, Thaxton C, Taniguchi R, Zhang W, Bai H, Yatsula B, Dardik A. A central arteriovenous fistula reduces systemic hypertension in a mouse model. JVS Vascular Science 2024, 5: 100191. PMID: 38510938, PMCID: PMC10951512, DOI: 10.1016/j.jvssci.2024.100191.Peer-Reviewed Original ResearchCentral arteriovenous fistulaArteriovenous fistulaBlood pressureAng IISystemic hypertensionVenous remodelingArteriovenous fistula creationPCNA-positive cellsPostoperative day 7Systemic blood pressureSystolic blood pressureCollagen I depositionNormotensive miceRefractory hypertensionHypertensive miceC57BL6/J miceHypertensive environmentTreated patientsAngiotensin IIMouse modelDay 7HypertensionMiceFistulaAngHypertension Related Co-Morbidities and Complications in Women of Sub-Saharan Africa: A Brief Review
Hahka T, Slotkowski R, Akbar A, VanOrmer M, Sembajwe L, Ssekandi A, Namaganda A, Muwonge H, Kasolo J, Nakimuli A, Mwesigwa N, Ishimwe J, Kalyesubula R, Kirabo A, Berry A, Patel K. Hypertension Related Co-Morbidities and Complications in Women of Sub-Saharan Africa: A Brief Review. Circulation Research 2024, 134: 459-473. PMID: 38359096, PMCID: PMC10885774, DOI: 10.1161/circresaha.123.324077.Peer-Reviewed Original ResearchConceptsHypertensive disorders of pregnancyIncidence of hypertensive disorders of pregnancyCo-morbiditiesCardiovascular diseaseDisorders of pregnancyAwareness of hypertensionIndividual quality of lifeLong-term consequences of hypertensionRates of hypertensionPeripheral arterial diseaseLack of prevention programsQuality of lifeHypertensive disordersConsequences of hypertensionLives of womenDecrease morbidityTreatment strategiesUncontrolled hypertensionArtery diseaseKidney diseaseHypertensionPrevention programsKnowledge of causesHeart diseasePrevention strategiesHypertension Control During the Coronavirus Disease 2019 Pandemic
Korves C, Peixoto A, Lucas B, Davies L, Weinberger D, Rentsch C, Vashi A, Young-Xu Y, King J, Asch S, Justice A. Hypertension Control During the Coronavirus Disease 2019 Pandemic. Medical Care 2024, 62: 196-204. PMID: 38284412, PMCID: PMC10922611, DOI: 10.1097/mlr.0000000000001971.Peer-Reviewed Original ResearchConceptsHypertension controlFollow-up intervalPrimary care clinic visitsFollow-up lengthVeterans Health AdministrationControlled hypertensionUncontrolled hypertensionGeneralized estimating equationsCohort of individualsStudy inclusion criteriaHealth careHealth AdministrationLonger follow-up intervalsBlood pressure measurementsAssessed associationsClinic visitsInclusion criteriaDecreased likelihoodEstimating equationsPrepandemic periodLow likelihoodCoronavirus diseaseFollow-upHypertensionIndividuals
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