2025
Connectome-Based Predictive Modeling of PTSD Development Among Recent Trauma Survivors
Ben-Zion Z, Simon A, Rosenblatt M, Korem N, Duek O, Liberzon I, Shalev A, Hendler T, Levy I, Harpaz-Rotem I, Scheinost D. Connectome-Based Predictive Modeling of PTSD Development Among Recent Trauma Survivors. JAMA Network Open 2025, 8: e250331. PMID: 40063028, PMCID: PMC11894499, DOI: 10.1001/jamanetworkopen.2025.0331.Peer-Reviewed Original ResearchConceptsConnectome-based predictive modelingPosttraumatic stress disorderClinician-Administered PTSD Scale for DSM-5Months post-traumaFunctional magnetic resonance imagingTrauma survivorsDSM-5Post-traumaPosttraumatic stress disorder symptom clustersPosttraumatic stress disorder symptom severityPosttraumatic stress disorder symptom trajectoriesPosttraumatic stress disorder severityTask-based fMRI dataAnterior default modePredictive of symptomsFollow-up assessmentDevelopment of effective personalized treatmentsComprehensive clinical assessmentClinician-AdministeredNeurobiological indicesPosttraumatic psychopathologyHyperarousal symptomsCentral executiveTrauma exposureSalience networkPosttraumatic stress disorder and eating disorders: maintaining mechanisms and treatment targets
Mitchell K, Scioli E, Galovski T, Belfer P, Cooper Z. Posttraumatic stress disorder and eating disorders: maintaining mechanisms and treatment targets. 2025, 95-109. DOI: 10.4324/9781003607403-10.Peer-Reviewed Original ResearchPosttraumatic stress disorderStress disorderComorbid posttraumatic stress disorderPosttraumatic stress disorder symptomsExposure to interpersonal traumaCognitive behavioral theoryHistory of eating disordersLow self-worthEvidence-based treatmentsEmotion dysregulationHyperarousal symptomsInterpersonal traumaBinge eatingTrauma exposureED behaviorsLifetime historyEating disordersSelf-criticismSelf-worthEvidence-based therapiesTreatment of EDCoping strategiesBidirectional relationshipTreatment targetDisorders
2024
Associations of Posttraumatic Stress Disorder Symptom Clusters and Pain Interference in Post-9/11 Veterans: Exploring Sleep Impairment and Physical Activity as Underlying Mechanisms
Emrich M, Gnall K, Garnsey C, George J, Park C, Mazure C, Hoff R. Associations of Posttraumatic Stress Disorder Symptom Clusters and Pain Interference in Post-9/11 Veterans: Exploring Sleep Impairment and Physical Activity as Underlying Mechanisms. International Journal Of Behavioral Medicine 2024, 1-14. PMID: 38438749, DOI: 10.1007/s12529-024-10268-4.Peer-Reviewed Original ResearchPost-9/11 veteransPain interferencePhysical activityPTSD symptomsAssociated with pain interferenceModifiable health factorsSleep impairmentSymptom clustersPosttraumatic stress disorder symptom clustersWorsening pain interferencePTSD symptom clustersRe-experiencing symptomsBackgroundPosttraumatic stress disorderHealth factorsSecondary analysisTargeting sleepMethodsThe present studyVeteransHyperarousal symptomsRe-experiencingStress disorderStudy variablesPTSDPainAssociated with changes
2021
Differential Patterns of Delayed Emotion Circuit Maturation in Abused Girls With and Without Internalizing Psychopathology
Keding T, Heyn S, Russell J, Zhu X, Cisler J, McLaughlin K, Herringa R. Differential Patterns of Delayed Emotion Circuit Maturation in Abused Girls With and Without Internalizing Psychopathology. American Journal Of Psychiatry 2021, 178: 1026-1036. PMID: 34407623, PMCID: PMC8570983, DOI: 10.1176/appi.ajp.2021.20081192.Peer-Reviewed Original ResearchConceptsChildhood abusePhysical neglectBrain Age Gap EstimationNormative brain developmentCircuit maturationBrain-wide patternsChildhood physical neglectEarly life adversityFronto-parietal cortexEmotion circuitsThreat generalizationGray matter volumePresence of psychopathologyResilient girlsLateral prefrontalHyperarousal symptomsInternalizing psychopathologyNeural contributorsAbused girlsInternalizing disorder diagnosesInternalizing diagnosesMaltreatment historyAbuse exposureAbuse historyNeurodevelopmental markersPosttraumatic stress disorder and eating disorders: maintaining mechanisms and treatment targets
Mitchell K, Scioli E, Galovski T, Belfer P, Cooper Z. Posttraumatic stress disorder and eating disorders: maintaining mechanisms and treatment targets. Eating Disorders 2021, 29: 292-306. PMID: 33411646, DOI: 10.1080/10640266.2020.1869369.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderStress disorderComorbid posttraumatic stress disorderCognitive-behavioral theoryImpulsivity/compulsivityEvidence-based treatmentsEmotion dysregulationInterpersonal traumaNegative affectTreatment targetsTrauma exposurePTSD symptomsHyperarousal symptomsED behaviorsBehavioral theoryPotential treatment targetBidirectional relationshipLifetime historyEvidence-based therapiesIntegrated modelFuture directionsDisordersTheoretical modelAngerCompulsivity
2020
Dynamic interplay between PTSD symptoms and posttraumatic growth in older military veterans
Whealin JM, Pitts B, Tsai J, Rivera C, Fogle BM, Southwick SM, Pietrzak RH. Dynamic interplay between PTSD symptoms and posttraumatic growth in older military veterans. Journal Of Affective Disorders 2020, 269: 185-191. PMID: 32339132, DOI: 10.1016/j.jad.2020.03.020.Peer-Reviewed Original ResearchConceptsGreater posttraumatic growthPosttraumatic stress disorderPosttraumatic growthPTSD symptomsActive copingReligious copingOlder military veteransPositive psychological changesSubsequent posttraumatic growthMilitary veteransChronic PTSD symptomsWave 2Self-report natureSpecific symptom clustersAnxious arousalDysphoric arousalGreater severityHyperarousal symptomsTraumatic eventsPsychological changesStress disorderCopingSymptom clustersLongitudinal studyWave 3
2019
Posttraumatic Stress Disorder Symptoms, Functioning, and Suicidal Ideation in US Military Veterans: A Symptomics Approach.
Kachadourian LK, Harpaz-Rotem I, Tsai J, Southwick SM, Pietrzak RH. Posttraumatic Stress Disorder Symptoms, Functioning, and Suicidal Ideation in US Military Veterans: A Symptomics Approach. The Primary Care Companion For CNS Disorders 2019, 21 PMID: 31050228, DOI: 10.4088/pcc.18m02402.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderPositive affectMeasures of functioningCognitive functioningNegative thoughtsPTSD symptomsConcentration difficultiesSleep difficultiesTreatment of PTSDUS military veteransSeverity of PTSDPosttraumatic stress disorder (PTSD) symptomsSuicidal ideationDSM-5 PTSD symptomsMilitary veteransLifetime trauma burdenIrritability/aggressionHyperarousal symptomsDisorder symptomsStress disorderPsychogenic amnesiaPTSD diagnosisQuality of lifeMental functioningMost variance
2014
Comparison of Clinician‐ and Self‐Assessments of Posttraumatic Stress Symptoms in Older Versus Younger Veterans
Lunney CA, Schnurr PP, Cook JM. Comparison of Clinician‐ and Self‐Assessments of Posttraumatic Stress Symptoms in Older Versus Younger Veterans. Journal Of Traumatic Stress 2014, 27: 144-151. PMID: 24700623, DOI: 10.1002/jts.21908.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderOlder veteransYounger veteransPTSD symptomsOlder adultsHyperarousal symptomsSymptoms of PTSDAge 60 yearsSeparate clinical trialsSelf-reported symptomsComparison of clinicianClinical trialsEffective treatmentOlder womenOlder menPosttraumatic stress symptomsPTSD symptom presentationFemale veteransSymptom presentationU.S. veteransSymptomsClinician ratingsStress disorderVeteransStress symptoms
2013
Maladaptive Dependency Schemas, Posttraumatic Stress Hyperarousal Symptoms, and Intimate Partner Aggression Perpetration
Kachadourian LK, Taft CT, Holowka DW, Woodward H, Marx BP, Burns A. Maladaptive Dependency Schemas, Posttraumatic Stress Hyperarousal Symptoms, and Intimate Partner Aggression Perpetration. Journal Of Traumatic Stress 2013, 26: 580-587. PMID: 24030885, DOI: 10.1002/jts.21850.Peer-Reviewed Original ResearchConceptsPhysical aggression perpetrationHyperarousal symptomsAggression perpetrationPhysical aggressionDependency schemasIntimate partner aggression (IPA) perpetrationIntervention programsSevere psychological aggressionMild physical aggressionPartner aggression perpetrationPerpetration of aggressionPTSD hyperarousal symptomsCourt-referred menPsychological aggressionIntimate aggressionGreater endorsementPossible moderatorsAggressionMultiple regression analysisPerpetrationFuture researchProblematic dependenciesRelated variablesSignificant interactionSchema
2010
Agreement of Parent and Child Reports of Trauma Exposure and Symptoms in the Early Aftermath of a Traumatic Event
Stover CS, Hahn H, Berkowitz S, Im J. Agreement of Parent and Child Reports of Trauma Exposure and Symptoms in the Early Aftermath of a Traumatic Event. Psychological Trauma Theory Research Practice And Policy 2010, 2: 159-168. PMID: 21572906, PMCID: PMC3093053, DOI: 10.1037/a0019156.Peer-Reviewed Original ResearchChild reportsPsychological functioningTraumatic eventsChildren's psychological functioningChild trauma historyImpact of traumaAgreement of parentsChild distressTrauma exposurePTSD symptomsTraumatic exposureHyperarousal symptomsTrauma historyParental acknowledgementSubjective reportsNon-significant agreementEarly aftermathPhysical assaultEarly interventionCommon experienceParentsDistressChildrenSerious accidentsPTSD
2002
Regulating Acute Posttrauma Distress
Fauerbach J, Richter L, Lawrence J. Regulating Acute Posttrauma Distress. Journal Of Burn Care & Research 2002, 23: 249-257. PMID: 12142577, DOI: 10.1097/00004630-200207000-00005.Peer-Reviewed Original ResearchConceptsLevels of posttraumatic stress disorder symptomsPosttraumatic stress disorder symptomsPosttraumatic stress symptomsStress disorder symptomsCoping methodsHyperarousal symptomsDisorder symptomsMental controlVenting emotionsStress symptomsBaseline symptomsMotivational frameworkMental distanceCopingSymptomsBurn-injured patientsEmotionsDistressSubjects
1999
Case Series: PTSD Symptoms in Adolescent Survivors of “Ethnic Cleansing.” Results From a 1‐Year Follow‐up Study
BECKER D, WEINE S, VOJVODA D, MCGLASHAN T. Case Series: PTSD Symptoms in Adolescent Survivors of “Ethnic Cleansing.” Results From a 1‐Year Follow‐up Study. Journal Of The American Academy Of Child & Adolescent Psychiatry 1999, 38: 775-781. PMID: 10361798, DOI: 10.1097/00004583-199906000-00027.Peer-Reviewed Original ResearchConceptsPTSD symptomsAssessment 1 yearPTSD severity scoresSeverity scorePsychiatric sequelaePosttraumatic stress disorder (PTSD) symptom severityDisorder symptom severityBaseline assessmentAssessment ScaleSymptom severitySymptomsAdolescent refugeesFollowHyperarousal symptomsAdolescent survivorsBaselineAvoidance symptomsFirst yearSubjectsVariety of factorsSequelaeBosnian refugeesGroupYearsCleansing
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