2025
Transient Ischemic Attack in Women: Real-World Hospitalization Incidence, Outcomes, and Risk of Hemorrhage and Stroke
Chen H, Khunte M, Colasurdo M, Majmundar S, Payabvash S, Chaturvedi S, Malhotra A, Gandhi D. Transient Ischemic Attack in Women: Real-World Hospitalization Incidence, Outcomes, and Risk of Hemorrhage and Stroke. Stroke 2025, 56: 285-293. PMID: 39869710, DOI: 10.1161/strokeaha.124.049278.Peer-Reviewed Original ResearchConceptsRates of vascular risk factorsTransient ischemic attackUS Census Bureau dataAssociated with lower oddsHigher odds of deathIschemic strokeRisk factorsAnnual incidenceTransient neurological symptomsStroke risk factorsOdds of deathLogistic regression modelsVascular risk factorsCensus Bureau dataRate of headacheRetrospective cohort studyLower oddsHigher oddsNeurological symptomsHome dischargeCohort studyIschemic attackHospital incidenceExcess hospitalizationsRisk of hemorrhage
2024
Endovascular thrombectomy versus medical management for patients with large vessel stroke and infective endocarditis
Chen H, Colasurdo M, Khunte M, Malhotra A, Gandhi D. Endovascular thrombectomy versus medical management for patients with large vessel stroke and infective endocarditis. Journal Of NeuroInterventional Surgery 2024, jnis-2024-022374. PMID: 39317440, DOI: 10.1136/jnis-2024-022374.Peer-Reviewed Original ResearchEfficacy of endovascular thrombectomyLarge vessel occlusionInfective endocarditisPropensity score matchingIntracerebral hemorrhageSubarachnoid hemorrhageMedical managementMultivariable adjustmentOdds of intracerebral hemorrhageEndovascular thrombectomyHome dischargeRate of intracerebral hemorrhageFavorable hospital outcomesRate of in-hospital deathAssociated with significantly higher oddsLarge vessel occlusion strokeIn-hospital mortalityRoutine home dischargeIn-hospital deathRate of subarachnoid hemorrhageRate of home dischargeSignificantly higher oddsRate of routine dischargePrimary outcomeSecondary outcomesAtrial Fibrillation: Prevalence and Association With Outcome in Patients With Stroke Undergoing Mechanical Thrombectomy in the United States
Otite F, Patel S, Hoffman H, Aneni E, Anikpezie N, Akano E, Wee C, Burke D, Albright K, Beutler T, Latorre J, Sonig A, Singla A, Morris N, Chaturvedi S, Khandelwal P. Atrial Fibrillation: Prevalence and Association With Outcome in Patients With Stroke Undergoing Mechanical Thrombectomy in the United States. Stroke Vascular And Interventional Neurology 2024, 4 DOI: 10.1161/svin.123.001248.Peer-Reviewed Original ResearchAcute ischemic strokeAF prevalenceJoinpoint regressionAtrial fibrillationIn-hospital deathIn-hospital outcomesMechanical thrombectomyDemographic subgroupsMultivariable-adjusted generalized linear modelsDemographic subgroups of patientsOdds of in-hospital deathCross-sectional studyNegative binomial regressionPrevalence of atrial fibrillationRoutine home dischargeNational Inpatient SampleAcute ischemic stroke populationAssociation of AFUnited StatesSubgroup of patientsHome dischargeBinomial regressionMultivariable adjustmentRacial subgroupsInpatient SampleEndovascular thrombectomy versus medical management for acute basilar artery occlusion stroke in the elderly
Chen H, Colasurdo M, Khunte M, Malhotra A, Gandhi D. Endovascular thrombectomy versus medical management for acute basilar artery occlusion stroke in the elderly. American Journal Of Neuroradiology 2024, 46: ajnr.a8473. PMID: 39181691, PMCID: PMC11878975, DOI: 10.3174/ajnr.a8473.Peer-Reviewed Original ResearchPropensity score matchingBasilar artery occlusionIntracranial hemorrhageAssociated with higher ratesIn-hospital mortalityEndovascular thrombectomyIntravenous thrombolysisMedical managementAssociated with increased risk of ICHTreated with medical managementPatients treated with endovascular thrombectomyRisk of intracranial hemorrhageSafety of endovascular thrombectomyBasilar artery occlusion strokeFavorable hospital outcomesTreated with intravenous thrombolysisHome dischargeAssociated with increased riskEndovascular thrombectomy groupArtery occlusion strokeNational Inpatient SampleNIH Stroke ScalePropensity score-matched controlsStroke patientsHigher ratesEndovascular thrombectomy versus medical management for moderate-to-severe anterior cerebral artery occlusion stroke
Chen H, Khunte M, Malhotra A, Gandhi D, Colasurdo M. Endovascular thrombectomy versus medical management for moderate-to-severe anterior cerebral artery occlusion stroke. Journal Of Neurology 2024, 271: 6247-6254. PMID: 39085619, DOI: 10.1007/s00415-024-12582-z.Peer-Reviewed Original ResearchAssociated with higher oddsAnterior cerebral arteryAssociated with higher ratesIntracranial hemorrhageEndovascular thrombectomyMedical managementHigher oddsEfficacy of endovascular thrombectomyFavorable short-term outcomesRetrospective cohort studyPatient selection criteriaShort-term outcomesEndovascular thrombectomy patientsIn-hospital mortalityMultivariate logistic regressionHome dischargeArtery occlusion strokeNational Inpatient SampleHigher ratesNeurological outcomeCohort studyPrimary outcomeCerebral arterySecondary outcomesOcclusion stroke
2021
The modified 5-item frailty index is a predictor of perioperative risk in head and neck microvascular reconstruction: An analysis of 3795 cases
Panayi AC, Haug V, Kauke-Navarro M, Foroutanjazi S, Diehm YF, Pomahac B. The modified 5-item frailty index is a predictor of perioperative risk in head and neck microvascular reconstruction: An analysis of 3795 cases. American Journal Of Otolaryngology 2021, 42: 103121. PMID: 34171698, DOI: 10.1016/j.amjoto.2021.103121.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnastomosis, SurgicalDiabetes MellitusFemaleForecastingFrailtyHeadHeart FailureHumansHypertensionLength of StayMaleMicrovesselsMiddle AgedNeckOperative TimePlastic Surgery ProceduresPostoperative ComplicationsPulmonary Disease, Chronic ObstructiveSeverity of Illness IndexSurgical FlapsTreatment OutcomeConceptsNeck microvascular reconstructionMFI-5Microvascular reconstructionMFI scoreSubgroup analysisNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseChronic obstructive pulmonary diseaseFrailty index-5Non-home dischargeImprovement Program databaseAverage operative timeCongestive heart failureObstructive pulmonary diseasePost-operative outcomesPre-operative identificationPost-operative supportTerms of demographicsHospital stayPerioperative riskUnplanned readmissionHome dischargePostoperative outcomesYounger patientsFrailty index
2020
Aortic Valve Replacement for Severe Aortic Stenosis Before and During the Era of Transcatheter Aortic Valve Implantation
Akintoye E, Ando T, Sandio A, Adegbala O, Salih M, Zubairu J, Oseni A, Sistla P, Alqasrawi M, Egbe A, Mentias A, Afonso L, Briasoulis A, Panaich S, Desai M. Aortic Valve Replacement for Severe Aortic Stenosis Before and During the Era of Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2020, 126: 73-81. PMID: 32336533, DOI: 10.1016/j.amjcard.2020.03.038.Peer-Reviewed Original ResearchConceptsSevere aortic stenosisAortic valve replacementNational Inpatient SampleTAVI eraAortic stenosisMean annual changeValve replacementFavorable short-term outcomesTranscatheter aortic valve replacementTranscatheter aortic valve implantationRate of AVRAcute kidney injuryRate of strokeAortic valve implantationShort-term outcomesRisk-adjusted ratesHospital mortalityPre-TAVIHospital outcomesKidney injuryHome dischargeHospital dischargePacemaker implantationValve implantationMedian lengthAssociation between Hospital volume of cardiopulmonary resuscitation for in-hospital cardiac arrest and survival to Hospital discharge
Akintoye E, Adegbala O, Egbe A, Olawusi E, Afonso L, Briasoulis A. Association between Hospital volume of cardiopulmonary resuscitation for in-hospital cardiac arrest and survival to Hospital discharge. Resuscitation 2020, 148: 25-31. PMID: 31945429, DOI: 10.1016/j.resuscitation.2019.12.037.Peer-Reviewed Original ResearchConceptsNational Inpatient SampleHospital cardiac arrestHospital dischargeCase volumeCardiac arrestCases of IHCAHospital case volumeMedian case volumeNon-significant trendNon-linear associationHospital volumeHome dischargeHospital CPRYounger patientsInpatient SampleCardiopulmonary resuscitationHigh comorbidityBetter survivalFirst quartileIHCAHospitalQuartilePatientsStudy periodSurvival
2019
The Medicare Shared Savings Program and Outcomes for Ischemic Stroke Patients: a Retrospective Cohort Study
Kaufman B, O’Brien E, Stearns S, Matsouaka R, Holmes G, Weinberger M, Song P, Schwamm L, Smith E, Fonarow G, Xian Y. The Medicare Shared Savings Program and Outcomes for Ischemic Stroke Patients: a Retrospective Cohort Study. Journal Of General Internal Medicine 2019, 34: 2740-2748. PMID: 31452032, PMCID: PMC6854149, DOI: 10.1007/s11606-019-05283-1.Peer-Reviewed Original ResearchConceptsAccountable care organizationsIschemic strokeRecurrent strokeMSSP accountable care organizationsIndex hospital stayIncident ischemic strokeRetrospective cohort studyAcute care utilizationIschemic stroke patientsMedicare Shared Savings Program Accountable Care OrganizationsModerate ischemic strokeConclusionsAmong patientsMain MeasuresOutcomesCause readmissionHospital stayCohort studyHome dischargeCare utilizationStroke patientsTransitional careProbability of dischargeCare coordinationPatient outcomesMedicare claimsService beneficiariesClinical and economic burden of heparin-induced thrombocytopenia in hospitalized patients undergoing percutaneous peripheral arterial interventions
Subahi A, Osman M, Adegbala O, Abubakar H, Kheiri B, Yassin A, Khalid M, Akintoye E, Eljack A, Osman K, Alkhouli M. Clinical and economic burden of heparin-induced thrombocytopenia in hospitalized patients undergoing percutaneous peripheral arterial interventions. Vascular 2019, 28: 81-86. PMID: 31382836, DOI: 10.1177/1708538119868615.Peer-Reviewed Original ResearchConceptsVenous thrombosis/pulmonary embolismAcute kidney injuryKidney injuryIschemic strokePulmonary embolismHigh riskDeep venous thrombosis/pulmonary embolismPercutaneous peripheral arterial interventionsICD-9-CM codesHospital mortality differenceProlonged hospital stayHospital-level characteristicsPeripheral arterial interventionsNational Inpatient SampleHospital outcomesHospital stayIntervention patientsAbsence of heparinBaseline characteristicsHome dischargeLonger hospitalizationArterial interventionsHospitalized patientsInpatient SampleThrombocytopeniaEffect of Collaborative Telerehabilitation on Functional Impairment and Pain Among Patients With Advanced-Stage Cancer
Cheville AL, Moynihan T, Herrin J, Loprinzi C, Kroenke K. Effect of Collaborative Telerehabilitation on Functional Impairment and Pain Among Patients With Advanced-Stage Cancer. JAMA Oncology 2019, 5: 644-652. PMID: 30946436, PMCID: PMC6512772, DOI: 10.1001/jamaoncol.2019.0011.Peer-Reviewed Original ResearchConceptsPharmacological pain managementAdvanced-stage cancerArm 2Pain managementQuality of lifePain interferenceBrief Pain InventoryAcademic medical centerHealth care systemHousehold ambulatorsHospital lengthStage IIICHome dischargeMost patientsMonth 3Pain InventoryPostacute careArm 3Blinded assessmentCollaborative careControl armClinical trialsCare teamFunctional impairmentHematologic cancersOptimum age for performing Fontan operation in patients with univentricular heart
Akintoye E, Veldtman G, Miranda W, Connolly H, Egbe A. Optimum age for performing Fontan operation in patients with univentricular heart. Congenital Heart Disease 2019, 14: 138-139. PMID: 30945806, DOI: 10.1111/chd.12690.Peer-Reviewed Original Research
2018
In‐hospital outcomes of transcatheter mitral valve repair with Mitraclip in patients with pulmonary hypertension: Insights from the National Inpatient Sample
Ahmed A, Akintoye E, Adegbala O, Yassin A, Subahi A, Bangura L, Abubakar H, Elder M, Shokr M, Afonso L. In‐hospital outcomes of transcatheter mitral valve repair with Mitraclip in patients with pulmonary hypertension: Insights from the National Inpatient Sample. Catheterization And Cardiovascular Interventions 2018, 94: e30-e36. PMID: 30506974, DOI: 10.1002/ccd.27997.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCardiac CatheterizationClinical Decision-MakingDatabases, FactualFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospital MortalityHumansHypertension, PulmonaryMaleMiddle AgedMitral ValveMitral Valve InsufficiencyPatient SelectionPostoperative ComplicationsPrevalenceProsthesis DesignRecovery of FunctionRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsTranscatheter mitral valve repairNational Inpatient SamplePulmonary hypertensionMitral valve repairHospital outcomesValve repairInpatient SamplePre-existing pulmonary hypertensionPrevalence of PHPostoperative deep vein thrombosisAcute respiratory failureCohort of patientsDeep vein thrombosisMedian hospital costsHemorrhage requiring transfusionLength of stayPH groupCardiogenic shockPostoperative sepsisRespiratory failureHome dischargeInpatient mortalityPeriprocedural outcomesProhibitive riskPulmonary embolismTrends in Heart failure Hospitalization, In-hospital Mortality, Length of Stay and Disposition, Among ESRD patients on Dialysis (2001-2014)
Inampudi C, Akintoye E, Alvarez P, Bhama J, Briasoulis A. Trends in Heart failure Hospitalization, In-hospital Mortality, Length of Stay and Disposition, Among ESRD patients on Dialysis (2001-2014). Journal Of Cardiac Failure 2018, 24: s104. DOI: 10.1016/j.cardfail.2018.07.393.Peer-Reviewed Original ResearchLength of stayEnd-stage renal diseasePrimary HF admissionsHospital mortalityESRD patientsHeart failureHF admissionsEnd-stage renal disease patientsStage renal disease patientsAnnual national ratesPrimary HF hospitalizationsHeart failure hospitalizationRenal disease patientsBackground Cardiovascular diseaseNational Inpatient SampleRate of admissionAnnual percentage changeHF hospitalizationFailure hospitalizationHome dischargeRenal diseaseDisease patientsInpatient SampleCardiovascular diseaseCommon cause
2017
Effect of Hospital Ownership on Outcomes of Heart Failure Hospitalization
Akintoye E, Briasoulis A, Egbe A, Orhurhu V, Ibrahim W, Kumar K, Alliu S, Nas H, Levine D, Weinberger J. Effect of Hospital Ownership on Outcomes of Heart Failure Hospitalization. The American Journal Of Cardiology 2017, 120: 831-837. PMID: 28689752, DOI: 10.1016/j.amjcard.2017.06.009.Peer-Reviewed Original ResearchConceptsInpatient mortalityFemale patientsGovernment hospitalsHospitalization outcomesHospital ownershipSignificant differencesCharge of hospitalizationRoutine home dischargeHeart failure hospitalizationMean lengthNational Inpatient SampleCost of hospitalizationHF hospitalizationFailure hospitalizationHome dischargeHospital dischargeMale patientsInpatient SamplePrimary diagnosisProfit hospitalsHospitalizationMedian costMedian chargeMortality rateHospitalImpact of Surgeon Specialty on Perioperative Outcomes of Surgery for Benign Esophageal Diseases: A NSQIP Analysis
Khoshhal Z, Canner J, Schneider E, Stem M, Haut E, Schlottmann F, Barbetta A, Mungo B, Lidor A, Molena D. Impact of Surgeon Specialty on Perioperative Outcomes of Surgery for Benign Esophageal Diseases: A NSQIP Analysis. Journal Of Laparoendoscopic & Advanced Surgical Techniques 2017, 27: 924-930. PMID: 28594583, PMCID: PMC5749579, DOI: 10.1089/lap.2017.0083.Peer-Reviewed Original ResearchConceptsBenign esophageal diseaseGeneral surgeonsHeller esophagomyotomyEsophageal diseaseGS groupPerioperative outcomesHome dischargePEH repairSurgeon specialtyBetter outcomesMore home dischargesMultivariable logistic regressionParaesophageal hernia repairLower mortality rateNSQIP AnalysisHospital lengthOverall morbidityDischarge destinationGastric fundoplicationReadmission ratesLaparoscopic approachLow comorbidityShorter LOSACS-NSQIPBenign disease
2016
The older they are the harder they fall: Injury patterns and outcomes by age after ground level falls
Bhattacharya B, Maung A, Schuster K, Davis KA. The older they are the harder they fall: Injury patterns and outcomes by age after ground level falls. Injury 2016, 47: 1955-1959. PMID: 27346422, DOI: 10.1016/j.injury.2016.06.019.Peer-Reviewed Original ResearchMeSH KeywordsAccidental FallsAgedAged, 80 and overAnticoagulantsAspirinComorbidityFemaleFollow-Up StudiesFractures, BoneGeriatric AssessmentHospitalizationHumansInjury Severity ScoreIntracranial HemorrhagesMaleMultiple TraumaPlatelet Aggregation InhibitorsRetrospective StudiesSurvival AnalysisTrauma CentersTreatment OutcomeUnited StatesConceptsGround-level fallInjury patternsAnticoagulation useAspirin useIntracranial bleedAnticoagulation agentsAbdominal solid organ injuriesCertain injury patternsAdult trauma patientsSolid organ injuryAntiplatelet useHome dischargePatient characteristicsLife expectancy increasesMean ISSOrgan injuryOverall mortalityRetrospective reviewTrauma patientsGeriatric patientsSignificant morbidityTrauma centerPatient populationPelvic fracturesCervical spineDistinct Short-Term Outcomes in Patients With Mild Versus Rapidly Improving Stroke Not Treated With Thrombolytics
Romano J, Smith E, Liang L, Gardener H, Campo-Bustillo I, Khatri P, Bhatt D, Fonarow G, Sacco R, Schwamm L. Distinct Short-Term Outcomes in Patients With Mild Versus Rapidly Improving Stroke Not Treated With Thrombolytics. Stroke 2016, 47: 1278-1285. PMID: 26987870, DOI: 10.1161/strokeaha.115.011528.Peer-Reviewed Original ResearchConceptsHealth Stroke ScaleShort-term outcomesMild strokeHome dischargeIndependent ambulationStroke ScaleHealth Stroke Scale 0National InstituteGuidelines-Stroke registryVascular risk factorsLength of stayHospital mortalityHospital deathIschemic strokeSymptom onsetDischarge outcomesStroke presentationStroke symptomsHospital covariatesAdjusted outcomesRisk factorsWorse outcomesMultivariable modelRetrospective analysisGreater severity
2015
Patient Characteristics and Outcomes After Hemorrhagic Stroke in Pregnancy
Leffert LR, Clancy CR, Bateman BT, Cox M, Schulte PJ, Smith EE, Fonarow GC, Schwamm LH, Kuklina EV, George MG. Patient Characteristics and Outcomes After Hemorrhagic Stroke in Pregnancy. Circulation Cardiovascular Quality And Outcomes 2015, 8: s170-s178. PMID: 26515206, DOI: 10.1161/circoutcomes.115.002242.Peer-Reviewed Original ResearchConceptsStroke risk factorsSubarachnoid hemorrhage patientsHemorrhagic strokeRisk factorsHS patientsHospital mortalityHemorrhage patientsDiseases-Ninth Revision codesBlood pressure criteriaGuidelines-Stroke registryPregnancy-related strokeAssociation of pregnancyNonpregnant female patientsConditional logistic regressionFisher's exact testWilcoxon rank sum testRank sum testGuidelines-StrokeSevere preeclampsiaHome dischargeIschemic strokeNonpregnant womenPatient characteristicsRisk patientsIndependent ambulation
2013
New Utility for an Old Tool
Odonkor CA, Schonberger RB, Dai F, Shelley KH, Silverman DG, Barash PG. New Utility for an Old Tool. American Journal Of Physical Medicine & Rehabilitation 2013, 92: 849-863. PMID: 24051992, PMCID: PMC3850792, DOI: 10.1097/phm.0b013e3182a51ac5.Peer-Reviewed Original ResearchConceptsElective ambulatory surgeryUnplanned admissionsAmbulatory surgeryGait speedOdds ratioPrimary outcomeDischarge readinessProspective observational cohort studyMultivariable logistic regression modelSeparate multivariable logistic regression modelsEarly home dischargeHome discharge timePreoperative gait speedObservational cohort studyTotal anesthesia timeAdjusted odds ratioGait speed testingLogistic regression modelsCohort studyHome dischargeCardiac surgeryAnesthesia timeHeart rateSurgeryAdmission
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply