2025
Anatomy of Endovascular Arteriovenous Fistula Creation
Cornman-Homonoff J, Razdan R, Lozada J. Anatomy of Endovascular Arteriovenous Fistula Creation. Seminars In Interventional Radiology 2025, 42: 176-181. PMID: 40376219, PMCID: PMC12077948, DOI: 10.1055/s-0045-1805040.Peer-Reviewed Original Research
2024
Representation of female vascular surgeons in national clinical trial leadership: analysis of trends over 20 years
Kostiuk V, Thaxton C, Loh S, Cardella J, Dardik A, Tonnessen B. Representation of female vascular surgeons in national clinical trial leadership: analysis of trends over 20 years. JVS-Vascular Insights 2024, 2: 100077. DOI: 10.1016/j.jvsvi.2024.100077.Peer-Reviewed Original ResearchClinical trialsFemale vascular surgeonsVascular surgeonsMethods Clinical trialsArtery diseaseClinical trial leadershipSite principal investigatorsVascular conditionsAbdominal aortic aneurysmSurgeon-investigatorInvestigator-led trialsCarotid artery diseasePeripheral arterial diseaseCarotid diseaseProportion of womenVenous thrombectomyBoard certificationAortic aneurysmPercentage of womenIndustry-sponsored trialsTrial leadershipHemodialysis accessSubgroup analysisVascular surgerySurgeons
2023
High Incidence of Subclavian Vein Stenosis at the Thoracic Outlet in Patients with Ipsilateral Upper Extremity Hemodialysis Access
Harris S, Guzman R, Tonnessen B, Nassiri N, Chaar C, Aboian E, Cardella J, Strosberg D. High Incidence of Subclavian Vein Stenosis at the Thoracic Outlet in Patients with Ipsilateral Upper Extremity Hemodialysis Access. Journal Of Vascular Surgery 2023, 78: e140. DOI: 10.1016/j.jvs.2023.07.048.Peer-Reviewed Original Research
2021
A therapeutic vascular conduit to support in vivo cell-secreted therapy
Han EX, Qian H, Jiang B, Figetakis M, Kosyakova N, Tellides G, Niklason LE, Chang WG. A therapeutic vascular conduit to support in vivo cell-secreted therapy. Npj Regenerative Medicine 2021, 6: 40. PMID: 34326344, PMCID: PMC8322381, DOI: 10.1038/s41536-021-00150-2.Peer-Reviewed Original ResearchEnd-stage renal diseaseVascular conduitsLong-term efficacyVascular graftsHemoglobin levelsRenal diseaseCell-based therapiesMacrophage infiltrationCell transplantationHemodialysis accessAcellular vesselsLuminal obstructionSerum erythropoietinNude ratsClinical disordersCellular implantationEPO expressionErythropoietinGraftTherapyAdequate vascularizationBiological effects
2020
Artery to vein configuration of arteriovenous fistula improves hemodynamics to increase maturation and patency
Bai H, Sadaghianloo N, Gorecka J, Liu S, Ono S, Ramachandra AB, Bonnet S, Mazure NM, Declemy S, Humphrey JD, Dardik A. Artery to vein configuration of arteriovenous fistula improves hemodynamics to increase maturation and patency. Science Translational Medicine 2020, 12 PMID: 32817365, PMCID: PMC7705473, DOI: 10.1126/scitranslmed.aax7613.Peer-Reviewed Original ResearchConceptsArteriovenous fistulaHemodialysis accessNeointimal hyperplasiaEndothelial nitric oxide synthaseDurable surgical optionUremic male ratsRadial-cephalic arteriovenous fistulaKruppel-like factor 2Nitric oxide synthasePeak systolic velocityLong-term patencyReintervention rateSecondary patencyImproved hemodynamicsFemale patientsReimplantation techniqueSurgical optionsSystolic velocityMale ratsOxide synthaseFistula modelPatencyHemodynamicsDifferent hemodynamicsFemale animalsTGFβ (Transforming Growth Factor-Beta)–Activated Kinase 1 Regulates Arteriovenous Fistula Maturation
Hu H, Lee SR, Bai H, Guo J, Hashimoto T, Isaji T, Guo X, Wang T, Wolf K, Liu S, Ono S, Yatsula B, Dardik A. TGFβ (Transforming Growth Factor-Beta)–Activated Kinase 1 Regulates Arteriovenous Fistula Maturation. Arteriosclerosis Thrombosis And Vascular Biology 2020, 40: e203-e213. PMID: 32460580, PMCID: PMC7316601, DOI: 10.1161/atvbaha.119.313848.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAortaArteriovenous Shunt, SurgicalCells, CulturedCollagen Type IEndothelial CellsFibronectinsHumansJNK Mitogen-Activated Protein KinasesMaleMAP Kinase Kinase KinasesMechanotransduction, CellularMice, Inbred C57BLp38 Mitogen-Activated Protein KinasesPhosphorylationStress, MechanicalVascular PatencyVascular RemodelingVena Cava, InferiorConceptsArteriovenous fistulaAVF maturationNoncanonical TGFβSuccessful AVF maturationArteriovenous fistula maturationNovel therapeutic approachesTAK1 functionsFistula maturationHemodialysis accessDeposition of ECMLuminal diameterMouse endothelial cellsMaturation failureTherapeutic approachesLumen dilationControl veinsWall thickeningAVF modelOptimal conduitArterial magnitudesEndothelial cellsTAK1 phosphorylationCollagen 1Growth factorLaminar shear stressImpact of Body Mass Index on Outcomes of Autogenous Fistulas for Hemodialysis Access
Arhuidese I, Holscher C, Elemuo C, Parkerson G, Johnson B, Malas M. Impact of Body Mass Index on Outcomes of Autogenous Fistulas for Hemodialysis Access. Annals Of Vascular Surgery 2020, 68: 192-200. PMID: 32339695, DOI: 10.1016/j.avsg.2020.04.009.Peer-Reviewed Original ResearchConceptsBody mass indexImpact of body mass indexEnd-stage renal diseaseObesity class IObesity classAutogenous fistulasMass indexSpectrum of body mass indexPopulation-based cohort of patientsUnited States Renal Database SystemClass ILog-rank testCohort of patientsCox regression analysisPrevalence of obesityKaplan-Meier estimatesPopulation-based cohortTreatment of end-stage renal diseaseChi-square testAccess maturationNo significant differenceNormal weightRetrospective studyHemodialysis accessRenal diseaseOutcomes of autogenous fistulas and prosthetic grafts for hemodialysis access in diabetic and nondiabetic patients
Arhuidese I, Purohit A, Elemuo C, Parkerson G, Shames M, Malas M. Outcomes of autogenous fistulas and prosthetic grafts for hemodialysis access in diabetic and nondiabetic patients. Journal Of Vascular Surgery 2020, 72: 2088-2096. PMID: 32276026, DOI: 10.1016/j.jvs.2020.02.035.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overArteriovenous Shunt, SurgicalBlood Vessel Prosthesis ImplantationDatabases, FactualDiabetic NephropathiesFemaleHumansKidney Failure, ChronicMaleMiddle AgedPostoperative ComplicationsRenal DialysisRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesVascular PatencyConceptsProsthetic graft infectionAutogenous fistulasSecondary patencyProsthetic graftsNondiabetic patientsPopulation-based cohortGraft infectionPrimary patencyPrimary assistedHemodialysis accessPopulation-based cohort of patientsUnited States Renal Database SystemCohort of hemodialysis patientsPrimary fistula patencyPrimary assisted patencyLog-rank testKaplan-Meier analysisCohort of patientsCox regression analysisRetrospective cohort studyStudent's t-testEffects of diabetesProsthetic graft patencyAssisted patencyGraft recipientsRacial differences in utilization and outcomes of hemodialysis access in the Unites States
Arhuidese I, AJi E, Muhammad R, Dhaliwal J, Shukla A, Malas M. Racial differences in utilization and outcomes of hemodialysis access in the Unites States. Journal Of Vascular Surgery 2020, 71: 1664-1673. PMID: 32173190, DOI: 10.1016/j.jvs.2019.07.092.Peer-Reviewed Original ResearchConceptsAutogenous fistulasPatient survivalInitiation of HDProsthetic graftsPrimary-assistedSecondary patencyFistula maturationCatheter useHispanic patientsFistula placementHD accessAssociated with better patencyAssociated with worse patencyOutcomes of arteriovenous fistulaUnited States Renal Database SystemCohort of hemodialysisLog-rank testCox regression analysisRisk-adjusted oddsNo significant differenceArteriovenous fistulaGraft maturationKaplan-MeierRetrospective analysisHemodialysis accessAge-related outcomes of arteriovenous grafts for hemodialysis access
Arhuidese I, Beaulieu R, Aridi H, Locham S, Baldwin E, Malas M. Age-related outcomes of arteriovenous grafts for hemodialysis access. Journal Of Vascular Surgery 2020, 72: 643-650. PMID: 32067881, DOI: 10.1016/j.jvs.2019.10.096.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overArteriovenous Shunt, SurgicalBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationDatabases, FactualDevice RemovalFemaleGraft Occlusion, VascularHumansKidney Failure, ChronicMaleMiddle AgedProsthesis-Related InfectionsRenal DialysisReoperationRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVascular PatencyConceptsPrimary assisted patencyPopulation-based cohortGraft infectionAssisted patencySecondary patencyPrimary patencyNo significant differenceArteriovenous graftsHemodialysis accessOutcomes of arteriovenous graftsAge-related outcomesOlder age categoriesCohort of hemodialysis patientsProsthetic graft infectionArteriovenous graft placementEnd-stage renal diseaseLog-rank testPrevalence of end-stage renal diseaseKaplan-Meier analysisSignificant differenceCox regression analysisRetrospective cohort studyOlder ageGraft excisionU.S. Renal Data System
2019
Treatment of superior vena cava syndrome with kissing brachiocephalic stents and exchange of pacemaker leads
Ochoa Chaar C, Gholitabar N, Rezek I, Luciano R, Clancy J. Treatment of superior vena cava syndrome with kissing brachiocephalic stents and exchange of pacemaker leads. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2019, 8: 143-144. PMID: 31231057, DOI: 10.1016/j.jvsv.2019.04.009.Peer-Reviewed Original ResearchConceptsSuperior vena cava syndromeVena cava syndromeRecurrence of symptomsUpper extremity accessElectrophysiology teamMultidisciplinary managementKissing stentsBalloon angioplastySuperior venaBrachiocephalic veinComplex patientsHemodialysis accessCase reportChallenging complicationVascular surgeryPatientsSyndromeJoint proceduresPacemakerMultiple attemptsStentsAngioplastyHemodialysisComplicationsVena
2018
A prospective randomized study of bovine carotid artery biologic graft and expanded polytetrafluoroethylene for permanent hemodialysis access
Dakour Aridi H, Arhuidese I, Scudder M, Reifsnyder T, Malas M. A prospective randomized study of bovine carotid artery biologic graft and expanded polytetrafluoroethylene for permanent hemodialysis access. Journal Of Vascular Surgery 2018, 67: 1606-1612.e4. PMID: 29567027, DOI: 10.1016/j.jvs.2017.12.058.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAnimalsArteriovenous Shunt, SurgicalBaltimoreBlood Vessel ProsthesisCarotid ArteriesCattleClinical ProtocolsHeterograftsHumansKaplan-Meier EstimatePolytetrafluoroethyleneProportional Hazards ModelsProspective StudiesProsthesis DesignRenal DialysisResearch DesignTime FactorsTreatment OutcomeConceptsPermanent hemodialysis accessArteriovenous fistulaNative arteriovenous fistulaArteriovenous graftsBovine carotid arteryHemodialysis accessBiological graftsMultivariate Cox proportional regression analysisNational Kidney Foundation Kidney Disease Outcomes Quality Initiative guidelinesKidney Disease Outcomes Quality Initiative guidelinesKidney Foundation Kidney Disease Outcomes Quality Initiative guidelinesCox proportional regression analysisArteriovenous graft creationAVG placementEnd-stage renal diseasePrimary end pointTreatment of patientsVascular access patientsSynthetic arteriovenous graftsHistory of intoleranceYears of ageRandomized controlled trialsAcademic hospital centerReintervention rateFunctional patency
2017
Bovine carotid artery biologic graft outperforms expanded polytetrafluoroethylene for hemodialysis access
Arhuidese I, Reifsnyder T, Islam T, Karim O, Nejim B, Obeid T, Qazi U, Malas M. Bovine carotid artery biologic graft outperforms expanded polytetrafluoroethylene for hemodialysis access. Journal Of Vascular Surgery 2017, 65: 775-782. PMID: 28236920, DOI: 10.1016/j.jvs.2016.10.080.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnimalsBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationBody Mass IndexCarotid ArteriesCattleChi-Square DistributionFemaleGraft Occlusion, VascularGraft SurvivalHeterograftsHumansHyperlipidemiasKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMultivariate AnalysisObesityOdds RatioPolytetrafluoroethyleneProportional Hazards ModelsProsthesis DesignRenal DialysisRetreatmentRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeVascular PatencyConceptsPrimary assisted patencyCohort of patientsSecondary patencyBovine carotid arteryHemodialysis accessAssisted patencyBiological graftsArteriovenous graftsPredictors of graft failureSingle-institution retrospective reviewGraft infection rateHigher body mass indexLog-rank testAccess-related complicationsCox regression analysisPermanent hemodialysis accessMultivariate logistic analysisCharacteristics of patientsBody mass indexSociety for Vascular SurgeryEPTFE graftsPrimary patencyRetrospective reviewGraft complicationsArteriovenous fistula
2016
Proximal Versus Distal Fistula for Hemodialysis Access: Sacrificing Dogma for Functional First Fistula
Arhuidese I, Obeid T, Abularrage C, Nejim B, Zarkowsky D, Malas M. Proximal Versus Distal Fistula for Hemodialysis Access: Sacrificing Dogma for Functional First Fistula. Journal Of Vascular Surgery 2016, 63: 564-565. DOI: 10.1016/j.jvs.2015.11.030.Peer-Reviewed Original ResearchDistal fistulaHemodialysis access3 Next generation ECM-based vascular biomaterials
Brownson K, Dardik A. 3 Next generation ECM-based vascular biomaterials. 2016, 19-40. DOI: 10.1016/b978-0-08-100166-0.00003-7.ChaptersVascular biomaterialsCarotid endarterectomySynthetic scaffold materialsLong-term strokeSuperior clinical outcomesPericardial patch closureMedical implantsPrimary arteriotomy closureScaffold materialsPatch closureClinical outcomesPseudoaneurysm formationSurgical closureArterial occlusionAutologous veinHemodialysis accessPericardial patchArteriotomy closureDeath riskPatient outcomesDiseased vesselsCardiovascular surgeryUmbilical veinLower riskVascular surgery today
2015
Vascular access modifies the protective effect of obesity on survival in hemodialysis patients
Arhuidese I, Obeid T, Hicks C, Qazi U, Botchey I, Zarkowsky D, Reifsnyder T, Malas M. Vascular access modifies the protective effect of obesity on survival in hemodialysis patients. Surgery 2015, 158: 1628-1634. PMID: 26126794, DOI: 10.1016/j.surg.2015.04.036.Peer-Reviewed Original ResearchConceptsBody mass indexEnd-stage renal diseaseNormal body mass indexProtective effect of obesityHigher body mass indexEffect of obesityObesity paradoxProtective effect of increasing BMIEffect of increased BMIBody mass index statusMass indexHD accessProtective effectAssociated with lower mortalityPropensity score matching analysisSurvival of patientsScore matching analysisSurvival benefitImproved survivalRetrospective studyHemodialysis accessInitiate hemodialysisPatient backgroundRenal diseaseCox regressionRacial/Ethnic Disparities Associated With Initial Hemodialysis Access
Zarkowsky DS, Arhuidese IJ, Hicks CW, Canner JK, Qazi U, Obeid T, Schneider E, Abularrage CJ, Freischlag JA, Malas MB. Racial/Ethnic Disparities Associated With Initial Hemodialysis Access. JAMA Surgery 2015, 150: 529-536. PMID: 25923973, DOI: 10.1001/jamasurg.2015.0287.Peer-Reviewed Original ResearchConceptsMedical insurance statusEnd-stage renal diseaseUS Renal Data SystemInitial hemodialysis accessWhite patientsArteriovenous fistulaBlack patientsHispanic patientsRace/ethnicityNephrology careInsurance statusRenal diseaseHemodialysis accessChronic obstructive pulmonary diseaseLogistic regressionMore white patientsInfluence of comorbiditiesObstructive pulmonary diseaseRacial/Ethnic DisparitiesCoronary artery diseaseCategory of patientsMultivariable logistic regressionPatterns of utilizationDifferent races/ethnicitiesFistula utilization
2001
Use of cryopreserved cadaveric vein allograft for hemodialysis access precludes kidney transplantation because of allosensitization
Benedetto B, Lipkowitz G, Madden R, Kurbanov A, Hull D, Miller M, Bow L. Use of cryopreserved cadaveric vein allograft for hemodialysis access precludes kidney transplantation because of allosensitization. Journal Of Vascular Surgery 2001, 34: 139-142. PMID: 11436087, DOI: 10.1067/mva.2001.114206.Peer-Reviewed Original ResearchConceptsVein allograftsHemodialysis accessPRA valuesControl cohortPRA assaysWaiting listKidney transplantation waiting listPanel-reactive antibodies valuesPotential kidney transplant recipientsUniversity-affiliated medical centerMajor histocompatibility complex IKidney transplant recipientsHistory of transfusionTransplant waiting listTransplantation waiting listMean PRANonimmunosuppressed individualsHemodialysis populationKidney transplantationPrior transplantationTransplant recipientsConsecutive patientsProsthetic graftsAntibody valuesKidney failure
2000
First hemodialysis access selection varies with patient acuity.
Friedman A, Walworth C, Meehan C, Wander H, Shemin D, DeSoi W, Kitsen J, Hill C, Lambert C, Mesler D. First hemodialysis access selection varies with patient acuity. Advances In Kidney Disease And Health 2000, 7: s4-10. PMID: 11053581.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAgedArteriovenous Shunt, SurgicalBlood Vessel ProsthesisCatheters, IndwellingCenters for Medicare and Medicaid Services, U.S.FemaleHumansKidney Failure, ChronicMaleMiddle AgedPatient SelectionRenal DialysisSeverity of Illness IndexTotal Quality ManagementUnited StatesConceptsEnd-stage renal diseaseQuality improvement projectInitial hemodialysis accessNew ESRD patientsIncident dialysis patientsPermanent vascular accessMonths of dialysisVascular access selectionQuality improvement guidelinesIncident patientsDialysis requirementESRD patientsRenal insufficiencyDialysis patientsRenal diseasePatient's courseHemodialysis accessPatient groupVascular accessUnknown patientsPatient acuityPatientsClinical groupsFistulaCare quality
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