2025
The Implications of Oxygen-Dependent Chronic Obstructive Pulmonary Disease on Sac Growth and Mortality Following Endovascular Aneurysm Repair
Bellamkonda K, Suckow B, Columbo J, Upchurch G, Jacobs B, Ochoa Chaar C, Scully R, Goodney P, Scali S, Stone D. The Implications of Oxygen-Dependent Chronic Obstructive Pulmonary Disease on Sac Growth and Mortality Following Endovascular Aneurysm Repair. Annals Of Vascular Surgery 2025, 115: 98-106. PMID: 40081526, DOI: 10.1016/j.avsg.2025.02.019.Peer-Reviewed Original ResearchChronic obstructive pulmonary diseaseEndovascular AAA repairObstructive pulmonary diseaseSac growthImpact of chronic obstructive pulmonary diseaseOxygen-dependent chronic obstructive pulmonary diseaseEffect of COPD severityCox proportional hazards regressionElective endovascular AAA repairAAA-related mortalityPulmonary diseaseChronic obstructive pulmonary disease severityChronic obstructive pulmonary disease patientsLimited life expectancyIncreased reintervention rateAbdominal aortic aneurysm (AAAEndovascular aneurysm repairElevated mortality ratesPredictors of mortalityPrimary exposureHazards regressionInclusion criteriaIncreased reinterventionsLogistic regressionPost-EVARUsing Radiology as a Screening Tool to Identify Intimate Partner Violence
Lenehan P, Tang A, Watane G, Gujrathi R, Park H, Gosangi B, Thomas R, Franco F, Patel K, Warsofsky I, Rosner B, Khurana B. Using Radiology as a Screening Tool to Identify Intimate Partner Violence. Journal Of The American College Of Radiology 2025, 22: 395-404. PMID: 40044319, PMCID: PMC11887577, DOI: 10.1016/j.jacr.2025.01.003.Peer-Reviewed Original ResearchConceptsAdjusted incidence rate ratiosEmergency departmentRetrospective case-control studyImaging utilization patternsEvident injuriesCox proportional hazards regressionRace-matched controlsCase-control studyTime-to-event analysisProportional hazards regressionImaging utilizationIncidence rate ratiosCumulative incidenceAnatomical sitesScreening mammogramsHazards regressionOdds ratioImaging studiesIntimate partner violencePatientsInjury patternsLogistic regressionInjuryOrgan systemsPoisson regressionIndustrial air emissions and breast cancer incidence in a United States-wide prospective cohort.
Ish J, Madrigal J, Pearce J, Keil A, Fisher J, Jones R, Sandler D, White A. Industrial air emissions and breast cancer incidence in a United States-wide prospective cohort. Epidemiology 2025 PMID: 39855262, DOI: 10.1097/ede.0000000000001837.Peer-Reviewed Original ResearchBreast cancer incidenceCancer incidenceBreast cancerIncidence of breast cancerEstimate adjusted hazard ratiosHazard ratioAssociated with breast cancerIncident breast cancerConfidence intervalsBreast cancer casesAdjusted hazard ratiosCox proportional hazards regressionProportional hazards regressionParticipating residentsCancer casesHazards regressionProspective cohortStudy enrollmentElevated associationIndustrial air emissionsIndustrial carcinogensCharacterized associationsBreastFollow-upPollutant mixturesHepatic Biomarker Abnormalities in the Cardiac Intensive Care Unit Proposed Criteria for Cardiohepatic Syndrome
Butt A, Padkins M, Crespo-Diaz R, Hillerson D, Katz J, Kamath P, Miller P, Rosenbaum A, Samsky M, Kashani K, Jentzer J. Hepatic Biomarker Abnormalities in the Cardiac Intensive Care Unit Proposed Criteria for Cardiohepatic Syndrome. JACC Advances 2025, 4: 101464. PMID: 39850044, PMCID: PMC11755386, DOI: 10.1016/j.jacadv.2024.101464.Peer-Reviewed Original ResearchCardiac intensive care unitLiver function testsIn-hospital mortalityLiver function test abnormalitiesAbnormal liver function testsCardiac intensive care unit patientsCardiac intensive care unit populationLFT valuesCardiohepatic syndromeCox proportional hazards regressionRisk prediction toolsAdmission liver function testsAssociated with higher in-hospital mortalityProportional hazards regressionAssociated with in-hospitalHistorical cohort studyHigher in-hospital mortalityEvaluate in-hospital mortalityOne-year mortalityPredictor of prognosisLiver synthetic dysfunctionIntensive care unitCohort studyHazards regressionLogistic regression
2024
Ursodeoxycholic acid and severe COVID-19 outcomes in a cohort study using the OpenSAFELY platform
Costello R, Waller K, Smith R, Mells G, Wong A, Schultze A, Mahalingasivam V, Herrett E, Zheng B, Lin L, MacKenna B, Mehrkar A, Bacon S, Goldacre B, Tomlinson L, Tazare J, Rentsch C. Ursodeoxycholic acid and severe COVID-19 outcomes in a cohort study using the OpenSAFELY platform. Communications Medicine 2024, 4: 238. PMID: 39562612, PMCID: PMC11576861, DOI: 10.1038/s43856-024-00664-y.Peer-Reviewed Original ResearchCOVID-19 hospitalisationSevere COVID-19 outcomesCOVID-19 related hospitalisationCOVID-19 outcomesCohort studyPopulation-based cohort studyHazard ratioPrimary care recordsDeath registration dataOpenSAFELY-TPP platformApproval of NHS EnglandConfidence intervalsEstimate hazard ratiosCox proportional hazards regressionProportional hazards regressionPre-specified confoundersAbsolute risk reductionOpenSAFELY platformCare recordsNHS EnglandConfounder adjustmentEligible individualsRegistration dataHazards regressionHospital recordsAnticoagulation Alone vs Anticoagulation Plus Aspirin or DAPT Following Left Atrial Appendage Occlusion
Reinhardt S, Gibson D, Hsu J, Kapadia S, Yeh R, Price M, Piccini J, Nair D, Christen T, Allocco D, Freeman J. Anticoagulation Alone vs Anticoagulation Plus Aspirin or DAPT Following Left Atrial Appendage Occlusion. Journal Of The American College Of Cardiology 2024, 84: 889-900. PMID: 39197978, DOI: 10.1016/j.jacc.2024.05.067.Peer-Reviewed Original ResearchConceptsLeft atrial appendage occlusionRate of adverse eventsAdverse eventsLAA closure deviceAppendage occlusionAntithrombotic strategiesP2Y<sub>12</sub> inhibitorsDays of follow-upMultivariable Cox proportional hazards regressionClosure deviceRisk of adverse eventsCox proportional hazards regressionWatchman FLX deviceDual antiplatelet therapyDevice-related thrombusProportional hazards regressionStroke/transient ischemic attackAntithrombotic regimensFLX deviceAntiplatelet therapyDOACsGroup patientsFollow-upMultivariate analysisHazards regressionPancreatic Cancer Surveillance and Survival of High-Risk Individuals
Blackford A, Canto M, Dbouk M, Hruban R, Katona B, Chak A, Brand R, Syngal S, Farrell J, Kastrinos F, Stoffel E, Rustgi A, Klein A, Kamel I, Fishman E, He J, Burkhart R, Shin E, Lennon A, Goggins M. Pancreatic Cancer Surveillance and Survival of High-Risk Individuals. JAMA Oncology 2024, 10: 1087-1096. PMID: 38959011, PMCID: PMC11223057, DOI: 10.1001/jamaoncol.2024.1930.Peer-Reviewed Original ResearchHigh-risk individualsSurveillance of high-risk individualsScreening programPancreatic ductal adenocarcinomaScreening high-risk individualsPancreatic cancer surveillanceUS academic medical centersPopulation-based screeningConditional logistic regressionUS national dataCox proportional hazards regressionAcademic medical centerLead-time biasProportional hazards regressionYear of diagnosisControl patientsRisk regression modelCancer surveillanceComparative cohort studyMain OutcomesComparison cohortOverall survivalCohort studyHazards regressionNational dataQuantifying the Association between Pump Use and Breastfeeding Duration
Nardella D, Canavan M, Sharifi M, Taylor S. Quantifying the Association between Pump Use and Breastfeeding Duration. The Journal Of Pediatrics 2024, 274: 114192. PMID: 39004167, PMCID: PMC11499033, DOI: 10.1016/j.jpeds.2024.114192.Peer-Reviewed Original ResearchNon-Hispanic blacksBreastfeeding durationBreastfeeding cessationPump usePregnancy Risk Assessment Monitoring System dataAssociated with longer breastfeeding durationNon-Hispanic whitesMagnitude of associationAssociated with breastfeeding durationLonger breastfeeding durationCox proportional hazards regressionCross-sectional analysisProportional hazards regressionNative American participantsBreastfeeding inequitiesBreastfeeding outcomesInitiate breastfeedingLive-born infantsNon-missing dataUnmarried statusSurvey completionMonitoring system dataLow-incomeStratified analysisHazards regressionPharmacoepidemiology evaluation of bumetanide as a potential candidate for drug repurposing for Alzheimer's disease
Morales J, Gabriel N, Natarajan L, LaCroix A, Shadyab A, Xu R, Silverman J, Feldman H, Hernandez I, Aslanyan V, Bang A, Bevins E, Bowman G, Boyarko B, Chen X, Clelland C, Dodge H, Durant J, Edland S, Evans A, Galasko D, Gerwick W, Greenberg B, Herman M, Herold T, Hook V, Jacobs D, Kaye J, Kim D, Koo E, Kosik K, Léger G, Lupo J, Messer K, Momper J, Nygaard H, Pa J, Quinti L, Revta C, Rexach J, Rizzo S, Rynearson K, Schneider L, Slusher B, Tanzi R, Territo P, Yokoyama J. Pharmacoepidemiology evaluation of bumetanide as a potential candidate for drug repurposing for Alzheimer's disease. Alzheimer's & Dementia 2024, 20: 5236-5246. PMID: 39030734, PMCID: PMC11350022, DOI: 10.1002/alz.13872.Peer-Reviewed Original ResearchRisk of ADCross-sectional analysis of electronic health recordsAnalysis of electronic health recordsAD riskAssociated with risk of ADAssociated with AD riskAssociated with decreased prevalenceElectronic health recordsRetrospective cohort study designMedicare claims dataCohort study designCox proportional hazards regressionAssociated with riskCross-sectional analysisProportional hazards regressionPrevalence of ADMultiple sensitivity analysesAlzheimer's diseaseHealth recordsMedicare beneficiariesMedicare dataClaims dataStudy designHazards regressionPatient characteristicsOutcomes of a Formal Hematopoietic Cell Transplantation Survivorship Program on Screening for Late Effects
Newcomb R, Gao L, Vanderklish J, Tse A, Saylor M, Danielson C, Wali N, Frigault M, McAfee S, Spitzer T, DeFilipp Z, Chen Y, Amonoo H, El-Jawahri A. Outcomes of a Formal Hematopoietic Cell Transplantation Survivorship Program on Screening for Late Effects. Transplantation And Cellular Therapy 2024, 30: 700-711. PMID: 38685402, PMCID: PMC11223964, DOI: 10.1016/j.jtct.2024.04.018.Peer-Reviewed Original ResearchConceptsHematopoietic cell transplantationAllogeneic hematopoietic cell transplantationPromote screening adherencePost-HCTScreening adherenceCell transplantationPost-transplant complicationsSurvivorship programsCox proportional hazards regressionProportion of patientsPulmonary function testsProportional hazards regressionEndocrine evaluationMedian timeSecondary cancersRetrospective analysisEvaluate efficacyPrimary outcomeHazards regressionFunction testsPatientsLate effectsScreening outcomesScreening domainsTransfer careThe International Association for the Study of Lung Cancer Staging Project for Lung Cancer: Proposals for the Revision of the M Descriptors in the Forthcoming Ninth Edition of the TNM Classification for Lung Cancer
Fong K, Rosenthal A, Giroux D, Nishimura K, Erasmus J, Lievens Y, Marino M, Marom E, Putora P, Singh N, Suárez F, Rami-Porta R, Detterbeck F, Eberhardt W, Asamura H, Members of the International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee M. The International Association for the Study of Lung Cancer Staging Project for Lung Cancer: Proposals for the Revision of the M Descriptors in the Forthcoming Ninth Edition of the TNM Classification for Lung Cancer. Journal Of Thoracic Oncology 2024, 19: 786-802. PMID: 38320664, DOI: 10.1016/j.jtho.2024.01.019.Peer-Reviewed Original ResearchM1c patientsClassification of non-small cell lung cancerNon-small cell lung cancerLung Cancer Staging ProjectMultivariable-adjusted Cox proportional hazards regressionKaplan-Meier methodCell lung cancerCox proportional hazards regressionOrgan systemsProportional hazards regressionM1b categoryM1c categoryMetastatic categoriesMultiple metastasesMetastatic lesionsOverall survivalTNM classificationCurrent tumorLung cancerM categoryHazards regressionM descriptorsDecreased prognosisPotential confoundersMetastasisComparisons of Metabolic Measures to Predict T1D vs Detect a Preventive Treatment Effect in High-Risk Individuals
Sims E, Cuthbertson D, Jacobsen L, Ismail H, Nathan B, Herold K, Redondo M, Sosenko J. Comparisons of Metabolic Measures to Predict T1D vs Detect a Preventive Treatment Effect in High-Risk Individuals. The Journal Of Clinical Endocrinology & Metabolism 2024, 109: 2116-2123. PMID: 38267821, PMCID: PMC11244203, DOI: 10.1210/clinem/dgae048.Peer-Reviewed Original ResearchSix-month changesPrevention trialsC-peptidePredicting diabetesMetabolic endpointsPreventive treatment effectsMetabolic measuresEffect of disease-modifying therapiesProportional hazards regressionTreatment effectsResponse to immunotherapyMeasurement of glucoseNatural history studiesPrevention StudyHazards regressionInclusion criteriaDisease-modifying therapiesT1D prevention trialsComparing placeboTreatment armsTeplizumabTrialNet PathwayHigh riskDetect treatment effectsCombined glucoseHerpes Zoster and Risk of Incident Parkinson's Disease in US Veterans: A Matched Cohort Study
Tunnicliffe L, Weil R, Breuer J, Rodriguez‐Barradas M, Smeeth L, Rentsch C, Warren‐Gash C. Herpes Zoster and Risk of Incident Parkinson's Disease in US Veterans: A Matched Cohort Study. Movement Disorders 2024, 39: 438-444. PMID: 38226430, PMCID: PMC10922272, DOI: 10.1002/mds.29701.Peer-Reviewed Original ResearchConceptsUS Department of Veterans AffairsCohort studyRisk of incident PDDepartment of Veterans AffairsCox proportional hazards regressionIncident Parkinson's diseaseAssociated with increased riskHistory of HZMatched cohort studyProportional hazards regressionRisk of PDHerpes zosterIncident PDRisk of incident Parkinson's diseaseVeterans AffairsIncident HZUS veteransPD overallHazards regressionPD riskParkinson's diseaseIncreased riskMatched individualsUS DepartmentAssociated with Parkinson's disease
2023
Accordance to a MIND–Style Diet is Associated with Decreased Risk of Dementia Mortality in the REasons for Geographic and Racial Disparities in Stroke (REGARDS) Cohort
Judd S, Howard G, Tangney C, Pearson K, Shikany J, Cushman M, Wilson N, Howard V, Sawyer R, Oladele C, Manly J. Accordance to a MIND–Style Diet is Associated with Decreased Risk of Dementia Mortality in the REasons for Geographic and Racial Disparities in Stroke (REGARDS) Cohort. Alzheimer's & Dementia 2023, 19 DOI: 10.1002/alz.072481.Peer-Reviewed Original ResearchMIND diet scoreDiet scoreMIND dietDementia mortalityHigher MIND diet scoresDementia-related mortalityHistory of strokeNational Death IndexProportional hazards regressionBi-racial cohortMediterranean-DASH InterventionRate of dementiaBaseline cognitive impairmentNeurodegenerative Delay (MIND) dietDeath HRDementia deathCohort studyPrimary outcomeREGARDS cohortStroke cohortDietary interventionDeath IndexDecreased riskHazards regressionMedical conditionsHCC is associated with diabetes and longitudinal blood glucose control in a national cohort with cirrhosis
Mezzacappa C, Mahmud N, Serper M, John B, Taddei T, Kaplan D. HCC is associated with diabetes and longitudinal blood glucose control in a national cohort with cirrhosis. Hepatology Communications 2023, 7: e0344. PMID: 38055642, PMCID: PMC10984661, DOI: 10.1097/hc9.0000000000000344.Peer-Reviewed Original ResearchRate of HCCBlood glucose controlBG controlIncident HCCGlucose controlCox proportional hazards regressionEtiology of cirrhosisProportional hazards regressionUnited States veteransHemoglobin A1c measurementsCirrhosis careHgb A1cHCC ratesHazards regressionNational cohortHCC riskA1c measurementStates veteransCirrhosisHigh riskDiabetesSustained controlHCCControl stateCohortDifferential Effect of Consolidative Thoracic Radiation Therapy in Extensive-Stage Small Cell Lung Cancer Based on Sex
Jairam V, Soulos P, Madhav K, Gross C, Slotman B, Chiang A, Park H. Differential Effect of Consolidative Thoracic Radiation Therapy in Extensive-Stage Small Cell Lung Cancer Based on Sex. Advances In Radiation Oncology 2023, 9: 101413. PMID: 38778819, PMCID: PMC11110031, DOI: 10.1016/j.adro.2023.101413.Peer-Reviewed Original ResearchExtensive-stage small-cell lung cancerConsolidative thoracic radiotherapyProgression-free survivalSmall cell lung cancerCell lung cancerCREST trialThoracic radiotherapyLung cancerElectronic health record-derived databaseFirst-line systemic therapyStandard first-line treatmentCox proportional hazards regressionFirst-line treatmentNational practice patternsProportional hazards regressionSuperior OSInitial chemotherapyBaseline characteristicsSystemic therapyMale patientsFemale patientsPatient sexHazards regressionSurvival outcomesPractice patternsThe predictive validity of a Brain Care Score for dementia and stroke: data from the UK Biobank cohort
Singh S, Oreskovic T, Carr S, Papier K, Conroy M, Senff J, Chemali Z, Gutierrez-Martinez L, Parodi L, Mayerhofer E, Marini S, Nunley C, Newhouse A, Ouyang A, Brouwers H, Westover B, Rivier C, Falcone G, Howard V, Howard G, Pikula A, Ibrahim S, Sheth K, Yechoor N, Lazar R, Anderson C, Tanzi R, Fricchione G, Littlejohns T, Rosand J. The predictive validity of a Brain Care Score for dementia and stroke: data from the UK Biobank cohort. Frontiers In Neurology 2023, 14: 1291020. PMID: 38107629, PMCID: PMC10725202, DOI: 10.3389/fneur.2023.1291020.Peer-Reviewed Original ResearchRisk of dementiaIncident casesIncident dementiaCare scoresLower riskCox proportional hazards regressionSubsequent incident dementiaProportional hazards regressionUK Biobank cohortHazards regressionBaseline evaluationSignificant associationAge groupsDementiaBiobank cohortStrokeDelphi processLifestyle choicesPatientsUKB participantsRiskBaselineBehavior changeAssociationPredictive validityIncreasing Spiritual Beliefs are Associated With Lower HIV Incidence Among Black Men Who Have Sex With Men: Results From HPTN 061 Longitudinal Study
Ransome Y, Taggart T, Huang A, Vermund S, Mayer K, Nunn A. Increasing Spiritual Beliefs are Associated With Lower HIV Incidence Among Black Men Who Have Sex With Men: Results From HPTN 061 Longitudinal Study. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2023, 94: 196-202. PMID: 37850978, DOI: 10.1097/qai.0000000000003278.Peer-Reviewed Original ResearchConceptsHIV seroconversionHIV incidenceBehavioral HIV prevention interventionsLower HIV incidenceProportional hazards regressionHIV prevention interventionsBlack menSpiritual beliefsOne-unit increaseHazards regressionLongitudinal riskPrevention interventionsHIVBiomedical assessmentLower hazard rateLongitudinal studyMenMonthsSeroconversionLongitudinal analysisReligious service attendanceIncidenceBaselineBMSMHigher proportionArterial dissection during peripheral vascular interventions
Damara F, Alameddine D, Slade M, Cardella J, Tonnessen B, Guzman R, Ochoa Chaar C. Arterial dissection during peripheral vascular interventions. Journal Of Vascular Surgery 2023, 79: 339-347.e6. PMID: 37838217, DOI: 10.1016/j.jvs.2023.10.004.Peer-Reviewed Original ResearchPeripheral vascular interventionsReintervention-free survivalPeripheral arterial diseasePrimary patencyArterial dissectionLower primary patencyArterial diseaseVascular interventionsVascular Quality Initiative databaseLonger occlusion lengthAmputation-free survivalOutcomes of patientsHistory of smokingKaplan-Meier curvesProportional hazards regressionTrend of incidencePrimary endpointFemoropopliteal diseaseLimb outcomesEndovascular therapyFemoropopliteal segmentHazards regressionOpen surgeryOcclusion lengthTreatment modalitiesMaternal and Pregnancy Outcomes Following Heart Transplantation in the United States
Craig A, Campbell A, Snow S, Spates T, Goldstein S, Denoble A, Meng M, Schroder J, Flores K, Agarwal R, Ward C, Federspiel J. Maternal and Pregnancy Outcomes Following Heart Transplantation in the United States. JACC Heart Failure 2023, 11: 1666-1674. PMID: 37804312, PMCID: PMC10841668, DOI: 10.1016/j.jchf.2023.08.018.Peer-Reviewed Original ResearchNontransfusion severe maternal morbiditySevere maternal morbidityHT recipientsHeart transplantationPreterm birthDelivery hospitalizationsGreater oddsPregnancy outcomesRate of SMMNationwide Readmissions DatabaseOutcome of pregnancyHigher readmission ratesProportional hazards regressionHigh morbidity rateMaternal morbidityReadmission ratesHospital readmissionAdjusted analysisComorbid conditionsClinical comorbiditiesHazards regressionMorbidity rateHigh riskHT historyDays postpartum
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply