2023
W70. ASSOCIATION BETWEEN MBD5 GENE AND DEPRESSIVE SYMPTOMATOLOGY IN MEXICAN POPULATION: RESULTS FROM MXGDAR/ENCODAT COHORT
Camarena B, Sanabrais-Jiménez M, García A, Genis A, Villatoro-Velazquez J, Fleiz-Bautista C, Bustos-Gamiño M, Martínez-Magaña J, Nicolini H, Medina-Mora M. W70. ASSOCIATION BETWEEN MBD5 GENE AND DEPRESSIVE SYMPTOMATOLOGY IN MEXICAN POPULATION: RESULTS FROM MXGDAR/ENCODAT COHORT. European Neuropsychopharmacology 2023, 75: s141. DOI: 10.1016/j.euroneuro.2023.08.257.Peer-Reviewed Original ResearchDepressive symptomsAnxiety symptomsAnxiety disordersSubstantial disease burdenMexican populationGenetic principal componentsYears of lifeGeneralized anxiety disorderFindings of associationsDisease burdenHealthy controlsMexican cohortMajor depressiveGeneral populationDiagnostic criteriaLifetime symptomatologyGenetic overlapSymptomsMBD5 geneDepressiveBackground AnxietyCohortProtein 5DepressionGreater mortalityCardiothoracic complications of immune checkpoint inhibitors
Gosangi B, Wang Y, Rubinowitz A, Kwan J, Traube L, Gange C, Bader A. Cardiothoracic complications of immune checkpoint inhibitors. Clinical Imaging 2023, 102: 98-108. PMID: 37659356, DOI: 10.1016/j.clinimag.2023.08.001.Peer-Reviewed Educational MaterialsConceptsImmune checkpoint inhibitorsICI therapyCheckpoint inhibitorsOverall survivalTumor responseAdverse effectsDevelopment of irAEsNovel adverse effectsImproved overall survivalOverall patient outcomesICI administrationHematologic malignanciesPatient outcomesSolid tumorsIrAEsCancer treatmentGreater mortalityComplicationsTherapySurvivalInhibitorsMyocarditisPneumonitisPatientsMalignancy
2022
A Narrative Review of the Association Between Depression and Heart Disease Among Women: Prevalence, Mechanisms of Action, and Treatment
Rome D, Sales A, Leeds R, Usseglio J, Cornelius T, Monk C, Smolderen KG, Moise N. A Narrative Review of the Association Between Depression and Heart Disease Among Women: Prevalence, Mechanisms of Action, and Treatment. Current Atherosclerosis Reports 2022, 24: 709-720. PMID: 35751731, PMCID: PMC9398966, DOI: 10.1007/s11883-022-01048-0.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseCardiovascular diseaseMechanism of actionHeart diseaseNarrative reviewManagement of depressionPrevalence of depressionRecent FindingsWomenCardiovascular outcomesAutonomic factorsDepression treatmentComorbid depressionTreatment inertiaGreater prevalenceTherapeutic targetPrevalenceStrong associationWomenDepressionDiseaseGreater mortalityTreatment effectsAssociationMenTreatment
1988
Mortality and Apnea Index in Obstructive Sleep Apnea Experience in 385 Male Patients
He J, Kryger M, Zorick F, Conway W, Roth T. Mortality and Apnea Index in Obstructive Sleep Apnea Experience in 385 Male Patients. CHEST Journal 1988, 94: 9-14. PMID: 3289839, DOI: 10.1378/chest.94.1.9.Peer-Reviewed Original ResearchConceptsApnea indexObstructive sleep apneaNasal CPAPOSA patientsCumulative survivalObstructive sleep apnea experienceEight-year survivalMale OSAS patientsUntreated OSA patientsGreater mortalityYears of ageUPPP patientsLatter patientsMale patientsSleep apneaPatientsSurvival curvesMortalityTracheostomyCPAPSurvivalIndexApneaUPPPTherapy
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