2025
Firearms lethal means safety among Veterans: Attitudes toward involving a concerned significant other
DeBeer B, Matthieu M, Degutis L, Clafferty S, Blessing A, Quan C, Morissette S. Firearms lethal means safety among Veterans: Attitudes toward involving a concerned significant other. Journal Of Military Veteran And Family Health 2025, 11: 23-31. DOI: 10.3138/jmvfh-2023-0094.Peer-Reviewed Original ResearchQuality improvement projectFirearm storageImprovement projectFirearm accessMixed-methods designStorage of firearmsFirearm storage practicesFirearm practicesMental healthSuicide preventionLethal meansQualitative interviewsSuicidal distressSafety interventionsDecreased riskVeteransFamily membersSuicidal thoughtsSuicidal ideationSuicideSafety needsCurrent practicesInterventionSuicide attemptsSafety planningQualitative Analysis of Symptoms from the Central Thalamic Deep Brain Stimulation Trial for Traumatic Brain Injury
Gerber L, Shulman K, Wright M, Schiff N, Fins J. Qualitative Analysis of Symptoms from the Central Thalamic Deep Brain Stimulation Trial for Traumatic Brain Injury. Neurorehabilitation 2025 DOI: 10.1177/10538135241296732.Peer-Reviewed Original ResearchStudy of deep brain stimulationTraumatic brain injuryDeep brain stimulation trialsDeep brain stimulationBrain injuryRandomized feasibility studySecondary qualitative analysisFamily membersSelf-regulationChronic traumatic brain injurySemi-structured interviewsBrain stimulationFamily perspectiveStimulation trialsTrial participantsExecutive controlResults SubjectsSymptom assessmentOutcome measuresQualitative analysisCognitive symptomsAnalysis of symptomsNarrative dataQualitative dataPost-injuryA STING–CASM–GABARAP pathway activates LRRK2 at lysosomes
Bentley-DeSousa A, Roczniak-Ferguson A, Ferguson S. A STING–CASM–GABARAP pathway activates LRRK2 at lysosomes. Journal Of Cell Biology 2025, 224: e202310150. PMID: 39812709, PMCID: PMC11734622, DOI: 10.1083/jcb.202310150.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAnimalsApoptosis Regulatory ProteinsAutophagy-Related Protein 8 FamilyEnzyme ActivationHEK293 CellsHumansLeucine-Rich Repeat Serine-Threonine Protein Kinase-2LysosomesMembrane ProteinsMiceMicrotubule-Associated ProteinsProtein Serine-Threonine KinasesSignal TransductionConceptsLRRK2 kinase activityKinase activityStimulator of interferon genesKinase activity of LRRK2Protein family membersLysosomal recruitmentLysosomal homeostasisEndogenous cellular mechanismsAberrant activationLRRK2Interferon genesLysosomesSingle membraneLysosomal damageMultiple chemical stimuliKinaseCellular mechanismsPathwayFamily membersChemical stimuliGABARAPMultiple stimuliGenesMutationsActivity
2024
HOW ARE FAMILIES INVOLVED IN THE CARE OF HOSPITALIZED OLDER ADULTS? A QUALITATIVE EVIDENCE SYNTHESIS
Vick J, Fogleman C, Neiman J, Cantrell S, Selmanoff M, Oyesanya T, Goldstein K, Van Houtven C. HOW ARE FAMILIES INVOLVED IN THE CARE OF HOSPITALIZED OLDER ADULTS? A QUALITATIVE EVIDENCE SYNTHESIS. Innovation In Aging 2024, 8: 682-683. PMCID: PMC11690992, DOI: 10.1093/geroni/igae098.2228.Peer-Reviewed Original ResearchHospitalization of older adultsOlder adultsFamily involvementEvidence synthesisCare of hospitalized older adultsSystematic review of qualitative researchActivities of daily livingReview of qualitative researchHands-on careHealth services researchQualitative evidence synthesisFamily membersMultidisciplinary research teamCaregiving tasksCINAHL CompleteCoordinated careIntervention developmentManaging deliriumDaily livingServices researchQualitative researchTitle/abstract screeningInternal medicineImpact of family involvementOutpatient settingNavigating life after New-onset refractory status epilepticus (NORSE) and Febrile infection-related epilepsy syndrome (FIRES): Insights from caregiver and patient interviews
Eschbach K, Reedy J, Gofton T, Gopaul M, Farias-Moeller R, Kellogg M, Knupp K, Hirsch L, Wong N, Dorsey Holliman B. Navigating life after New-onset refractory status epilepticus (NORSE) and Febrile infection-related epilepsy syndrome (FIRES): Insights from caregiver and patient interviews. Epilepsy & Behavior 2024, 163: 110236. PMID: 39740258, DOI: 10.1016/j.yebeh.2024.110236.Peer-Reviewed Original ResearchConceptsQuality of lifeCaregivers' quality of lifeDyadic semi-structured interviewsEmotional quality of lifeThematic content analysis approachComorbid health concernsHealth concernBehavioral health concernsContent analysis approachSignificant life changesMedication side effectsSemi-structured interviewsPatients' quality of lifeRisk of mortalityLife-altering impactPatient interviewsPatient independenceCaregiversNeurologically healthy individualsLife changesNew-onset refractory status epilepticusImpact patients' quality of lifeFebrile infection-related epilepsy syndromeFamily membersLong-term impactExperiences of Simulated Phone Death Notification
Murtha T, Johnson R, Ellman M, Martin A, Morrison L, Talwalkar J. Experiences of Simulated Phone Death Notification. The Clinical Teacher 2024, 22: e13846. PMID: 39710510, DOI: 10.1111/tct.13846.Peer-Reviewed Original ResearchConceptsCommunication skills workshopDeath notificationDebriefing sessionsSkills workshopMedical studentsFaculty-led debriefingFourth-year medical studentsCommunication skills curriculumCommunication challengesPatient encountersPostsession surveysAudio-recordedDidactic lessonsSense of safetyCoded responsesDebriefingMedical schoolsEmotional safetyFamily membersSkills curriculumTelephoneFormative peer feedbackExperiences of silenceThemesStudents expressed appreciationValidation of the NCCN/Yale criteria for the identification of CDH1 pathogenic variant carriers
Lerner B, Giner-Calabuig M, Carraway C, Richardson M, Krahn K, Susswein L, Nielsen S, Karam R, Xicola R, Llor X. Validation of the NCCN/Yale criteria for the identification of CDH1 pathogenic variant carriers. Journal Of Medical Genetics 2024, 62: 57-61. PMID: 39674581, PMCID: PMC11916899, DOI: 10.1136/jmg-2024-110446.Peer-Reviewed Original ResearchInternational Gastric Cancer Linkage ConsortiumInternational Gastric Cancer Linkage Consortium criteriaPV carriersLobular breast cancerGenetic tumor risk syndromesGenetic testingFamily membersEarly-onset diffuse gastric cancerPathogenic variant carriersGermline pathogenic variantsDiffuse gastric cancerPathogenic variantsEuropean Reference NetworkCancer geneticsRisk syndromeVariant carriersGenetics guidelinesEuropean cohortAutosomal-dominant syndromeBreast cancerCohortUS commercial laboratoryClinical dataGastric cancerCancerMentalization-Based Work with Families.
Asen E, Bleiberg E, Fonagy P. Mentalization-Based Work with Families. Psychodynamic Psychiatry 2024, 52: 563-583. PMID: 39679704, DOI: 10.1521/pdps.2024.52.4.563.Peer-Reviewed Original ResearchBarriers to Effective Infection Prevention in the Neonatal Intensive Care Unit
Weser V, Crocker A, Murray T, Wright J, Truesdell E, Ciaburri R, Marks A, Martinello R, Hieftje K, Team H. Barriers to Effective Infection Prevention in the Neonatal Intensive Care Unit. Advances In Neonatal Care 2024, 24: 475-484. PMID: 39196970, DOI: 10.1097/anc.0000000000001195.Peer-Reviewed Original ResearchConceptsPatients' family membersInfection preventionFamily membersGroup of nursesReduce nurses’ burdenHand hygieneHospital-wide surveyIntensive care unitInductive content analysisDesign of educational interventionsCare unitNeonatal intensive care unitImprove patient outcomesEffective infection preventionHH educationNursing burdenEducational interventionFrontline staffHospital staffNeonatal nursesIP educationPatient's familyRisk of infection transmissionFocus groupsIP behaviorA complex of the lipid transport ER proteins TMEM24 and C2CD2 with band 4.1 at cell–cell contacts
Johnson B, Iuliano M, Lam T, Biederer T, De Camilli P. A complex of the lipid transport ER proteins TMEM24 and C2CD2 with band 4.1 at cell–cell contacts. Journal Of Cell Biology 2024, 223: e202311137. PMID: 39158698, PMCID: PMC11334333, DOI: 10.1083/jcb.202311137.Peer-Reviewed Original ResearchConceptsPlasma membraneNon-vesicular lipid transferSites of cell contactC-terminus motifsCell contact-dependent signalsContact-dependent signalingCell-cell contactER/PM junctionsTMEM24ER proteinsPM proteinsSynCAM 1Cell adhesion moleculesCellular functionsLipid transferC2CD2Phospholipid transportLipid transportCell contactProteinAdhesion moleculesCalcium homeostasisCellsFamily membersParalogsOverlapping role of synaptophysin and synaptogyrin family proteins in determining the small size of synaptic vesicles
Park D, Fujise K, Wu Y, Luján R, Del Olmo-Cabrera S, Wesseling J, De Camilli P. Overlapping role of synaptophysin and synaptogyrin family proteins in determining the small size of synaptic vesicles. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2409605121. PMID: 38985768, PMCID: PMC11260120, DOI: 10.1073/pnas.2409605121.Peer-Reviewed Original ResearchConceptsSynaptic vesiclesFamily proteinsBiogenesis of synaptic vesiclesClusters of small vesiclesSize of synaptic vesiclesSynaptogyrin familySynaptogyrin-1Vesicle proteinsSynaptogyrinTransmembrane domainOrganismal levelSmall vesiclesProteinMild defectsVesiclesFamily membersBiogenesisSmall sizeFamilyMiceSynapsinCoexpressionAbundanceSynaptoporinMembersUnraveling the genetic tapestry of pediatric sarcomeric cardiomyopathies and masquerading phenocopies in Jordan
Azab B, Aburizeg D, Shaaban S, Ji W, Mustafa L, Isbeih N, Al-Akily A, Mohammad H, Jeffries L, Khokha M, Lakhani S, Al-Ammouri I. Unraveling the genetic tapestry of pediatric sarcomeric cardiomyopathies and masquerading phenocopies in Jordan. Scientific Reports 2024, 14: 15141. PMID: 38956129, PMCID: PMC11219879, DOI: 10.1038/s41598-024-64921-9.Peer-Reviewed Original ResearchConceptsExome sequencingSarcomere-related genesMitochondrial-related diseasesAt-risk family membersGenetic architectureGenetic landscapePathogenic variantsGene panelPediatric cardiomyopathyMolecular underpinningsGenetic testingPhenocopiesSarcomeric cardiomyopathiesGenesSequenceStorage disorderFamily membersAt-riskVariantsEarly interventionExomeFamilyGlycogen storage disorderHypertrophic cardiomyopathyCardiomyopathyDisorders with Ophthalmic and Thoracic Involvement.
Gosangi B, Lang P, Johnson M, Zukerman R, Tu L, Traube L, Bader A, Rubinowitz A. Disorders with Ophthalmic and Thoracic Involvement. RadioGraphics 2024, 44: e230132. PMID: 38870047, DOI: 10.1148/rg.230132.Peer-Reviewed Original ResearchConceptsClinical manifestationsExamination of family membersEhlers-Danlos syndromeAffecting patient outcomesAcute sarcoidosisOphthalmologic examinationThoracic symptomsDry eyeThoracic involvementOphthalmological symptomsOphthalmologic manifestationsEye symptomsMarfan syndromeSjogren's syndromeImaging findingsRadiological studiesLung diseasePatient outcomesEhlers-DanlosFamily membersMultimodal imagingSystem conditionsSyndromeThoracicSarcoidosisSHEA position statement on pandemic preparedness for policymakers: building a strong and resilient healthcare workforce
Banach D, Mathew T, Batshon L, Branch-Elliman W, Dumyati G, Haessler S, Hsu V, Jump R, Malani A, Murthy R, Pergam S, Shenoy E, Weber D. SHEA position statement on pandemic preparedness for policymakers: building a strong and resilient healthcare workforce. Infection Control And Hospital Epidemiology 2024, 45: 804-807. PMID: 38835227, PMCID: PMC11439590, DOI: 10.1017/ice.2024.62.Peer-Reviewed Original ResearchHealthcare personnelHealthcare workforceMental health impact of COVID-19US healthcare workforceHealth impact of COVID-19Shortage of cliniciansMental health impactsInfection prevention programsCOVID-19 pandemicHealthcare personnel infectionInpatient careHealthcare organizationsHealthcare epidemiologistsPost-acutePandemic preparednessPrevention programsInfection preventionCOVID-19Delegate tasksPosition statementWorkforce resilienceHealthcareImpact of COVID-19Increased workload demandsFamily membersPatterns in Receiving Informal Help With Childcare Among U.S. Parents During the COVID-19 Pandemic
Yang Y, Zang E, Calarco J. Patterns in Receiving Informal Help With Childcare Among U.S. Parents During the COVID-19 Pandemic. Journal Of Family Issues 2024, 46: 230-269. DOI: 10.1177/0192513x241257242.Peer-Reviewed Original ResearchInformal childcareInformal careU.S. parentsExtended family membersMothers of young childrenAssociated with long working hoursJob exitMaternal employmentLong working hoursChildcareChildcare closuresFamily membersParental useUS parentsWorking hoursInformation supportSocioeconomic statusU.S.ParentsCOVID-19 pandemicCOVID-19Young childrenGrandparentsNanniesCareEvaluation of lived experience Peer Support intervention for mental health service consumers in Primary Care (PS-PC): study protocol for a stepped-wedge cluster randomised controlled trial
Lawn S, Shelby-James T, Manger S, Byrne L, Fuss B, Isaac V, Kaambwa B, Ullah S, Rattray M, Gye B, Kaine C, Phegan C, Harris G, Worley P. Evaluation of lived experience Peer Support intervention for mental health service consumers in Primary Care (PS-PC): study protocol for a stepped-wedge cluster randomised controlled trial. Trials 2024, 25: 319. PMID: 38745299, PMCID: PMC11094922, DOI: 10.1186/s13063-024-08165-y.Peer-Reviewed Original ResearchConceptsStepped-wedge cluster randomised controlled trialCluster randomised controlled trialRandomised controlled trialsPeer support interventionPeer workersMental health conditionsPrimary careSecondary healthcare providersSupport interventionsHealth outcomesHealthcare providersHealth conditionsMental health service consumersManaging mental health conditionsMental health care sectorSecondary healthcare sectorsHealth service consumersControlled trialsMental health careMental health servicesPractice staff membersMental health outcomesJourney of recoveryFamily membersHealth care sector[Exploring a definition of healthy longevity in Chinese population based on Delphi method].
Chai X, Cui J, Ye L, Zhou J, Shao R, Shi X, Lyu Y, Zhang J. [Exploring a definition of healthy longevity in Chinese population based on Delphi method]. Chinese Preventive Medicine 2024, 58: 629-635. PMID: 38715502, DOI: 10.3760/cma.j.cn112150-20230924-00220.Peer-Reviewed Original ResearchConceptsHealthy longevityMental healthNon-communicable disease indicatorsSelf-rated healthTwo-round Delphi consultationCognitive functionWell-beingChinese populationFunctions of daily lifeHigh disability rateSubjective well-beingGeriatric healthDelphi consultationPhysical healthFunctional abilityHearing functionElderly care service industryDelphi surveyExpert consultationDisability rateHealthPublic healthMeasurement toolsMultiple-choice questionsFamily membersIL-23 past, present, and future: a roadmap to advancing IL-23 science and therapy
Krueger J, Eyerich K, Kuchroo V, Ritchlin C, Abreu M, Elloso M, Fourie A, Fakharzadeh S, Sherlock J, Yang Y, J. D, McInnes I. IL-23 past, present, and future: a roadmap to advancing IL-23 science and therapy. Frontiers In Immunology 2024, 15: 1331217. PMID: 38686385, PMCID: PMC11056518, DOI: 10.3389/fimmu.2024.1331217.Peer-Reviewed Original ResearchConceptsImmune-mediated inflammatory diseasesIL-23 inhibitionIL-23Anti-IL-23 therapyOptimal identification of patientsTreat immune-mediated inflammatory diseasesIL-12 cytokine family memberInterleukin (IL)-23Identification of patientsIL-23 signalingCytokine family membersInflammatory bowel diseaseMolecular ontologiesRegulatory cytokinesIL-12Psoriatic arthritisInflammatory diseasesBowel diseaseDiseaseTherapyFamily membersBiologyBuilding stronger bonds: The impact of family support and communication on suicidal behaviors among Black men who have sex with men
Boyd D, Quinn C, Jones K, Waller B, Coker E, Duprey E, Cerulli C, McCoy H. Building stronger bonds: The impact of family support and communication on suicidal behaviors among Black men who have sex with men. Suicide And Life-Threatening Behavior 2024, 55: e13072. PMID: 38488644, PMCID: PMC11401967, DOI: 10.1111/sltb.13072.Peer-Reviewed Original ResearchBlack menFamily supportYoung Black menDepressive symptomsRates of depressive symptomsImpact of family supportPrevent depressive symptomsSexual orientationMarginalized identitiesSuicide attemptsFamily membersYoung BMSMEffects of suicide attemptsAssociated with suicide plansTherapeutic servicesSuicide-related outcomesFamily factorsBMSMNegative outcomesSuicidal behaviorSuicide outcomesProtective factorsSuicide planMenPath analysisIdentifying trusted local sources and predicting behavior change pathways according to COVID-19 vaccination status: Results of a 2022 statewide survey of Alaskan adults
Cameron D, Grage L, Van Wyck R, Edwards A, Chavez Mapaye J, Cheng A, Garcia G. Identifying trusted local sources and predicting behavior change pathways according to COVID-19 vaccination status: Results of a 2022 statewide survey of Alaskan adults. Vaccine 2024, 42: 2592-2607. PMID: 38490821, PMCID: PMC11005074, DOI: 10.1016/j.vaccine.2024.03.027.Peer-Reviewed Original ResearchEmergency medical techniciansMedical techniciansCommunity membersCommunity trustSense of professional responsibilityVaccination statusCOM-B frameworkMedical professionalsTelephone-based surveyPredictors of vaccination statusPublic health challengeLocal community membersHealth workersReflective motivationHealthy choicesOpportunity domainHealth challengesUS averageDemographic characteristicsAdult populationRate of COVID-19 vaccinationProfessional responsibilityFamily membersAssess levelsStatewide survey
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