2025
PET Mapping of Receptor Occupancy Using Joint Direct Parametric Reconstruction
Marin T, Belov V, Chemli Y, Ouyang J, Najmaoui Y, Fakhri G, Duvvuri S, Iredale P, Guehl N, Normandin M, Petibon Y. PET Mapping of Receptor Occupancy Using Joint Direct Parametric Reconstruction. IEEE Transactions On Biomedical Engineering 2025, 72: 1057-1066. PMID: 39446540, PMCID: PMC11875991, DOI: 10.1109/tbme.2024.3486191.Peer-Reviewed Original ResearchCentral nervous systemReceptor occupancyLow-binding regionsPET scansSimulation resultsPreclinical in vivo experimentsDynamic PET scansPairs of baselineEstimation of receptor occupancyEstimation frameworkPET neuroimagingReconstruction frameworkModulating drugsTime activity curvesParametric reconstructionDevelopment of drugs
2024
Heteroscedastic Uncertainty Estimation Framework for Unsupervised Registration
Zhang X, Pak D, Ahn S, Li X, You C, Staib L, Sinusas A, Wong A, Duncan J. Heteroscedastic Uncertainty Estimation Framework for Unsupervised Registration. Lecture Notes In Computer Science 2024, 15002: 651-661. DOI: 10.1007/978-3-031-72069-7_61.Peer-Reviewed Original ResearchUnsupervised registrationReal-world medical imagesCollaborative training strategyMedical image datasetsDeep learning methodsAccurate displacement estimationSignal-to-noise ratioImage datasetsRegistration architectureLearning methodsMedical imagesTraining strategyNoise distributionUncertainty estimationWeighting schemeRegistration performanceSpatial domainEstimation frameworkInput-dependentUncertainty estimation frameworkUniform noise levelsDisplacement estimationFrameworkNoise levelUnsupervised
2023
Super-resolution in brain positron emission tomography using a real-time motion capture system
Chemli Y, Tétrault M, Marin T, Normandin M, Bloch I, El Fakhri G, Ouyang J, Petibon Y. Super-resolution in brain positron emission tomography using a real-time motion capture system. NeuroImage 2023, 272: 120056. PMID: 36977452, PMCID: PMC10122782, DOI: 10.1016/j.neuroimage.2023.120056.Peer-Reviewed Original ResearchConceptsBrain positron emission tomographySuper-resolutionEvent-by-event basisReal-time motion capture systemSR reconstruction methodTracking cameraVisualization of small structuresPET reconstruction algorithmMoving phantomMeasure target motionLine profilesPET/CT scannerMeasured shiftsImprove image resolutionMotion capture systemMotion tracking devicePositron emission tomographyReconstruction algorithmSpatial resolutionMeasured linesPhantomReal-timeEstimation frameworkIncreased spatial resolutionReconstruction method
2004
Neighbor-Constrained Segmentation With Level Set Based 3-D Deformable Models
Yang J, Staib LH, Duncan JS. Neighbor-Constrained Segmentation With Level Set Based 3-D Deformable Models. IEEE Transactions On Medical Imaging 2004, 23: 940-948. PMID: 15338728, PMCID: PMC2838450, DOI: 10.1109/tmi.2004.830802.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsBrainComputer SimulationElasticityHumansImage EnhancementImage Interpretation, Computer-AssistedImaging, Three-DimensionalInformation Storage and RetrievalMagnetic Resonance ImagingModels, BiologicalModels, StatisticalNumerical Analysis, Computer-AssistedPattern Recognition, AutomatedReproducibility of ResultsSensitivity and SpecificitySignal Processing, Computer-AssistedConceptsThree-dimensional medical imagesImage gray level informationGray level informationPoint distribution modelMedical imagesNeighbor objectsTraining imagesMedical imageryMultiple objectsDeformable modelObject shapeSynthetic dataLevel informationSegmentationMap shapeEstimation frameworkPosition relationshipPrior informationLevel set functionObjectsJoint probability distributionSet functionNeighboring shapesInformationImages
2003
Neighbor-Constrained Segmentation with 3D Deformable Models
Yang J, Staib LH, Duncan JS. Neighbor-Constrained Segmentation with 3D Deformable Models. Lecture Notes In Computer Science 2003, 18: 198-209. PMID: 15344458, DOI: 10.1007/978-3-540-45087-0_17.Peer-Reviewed Original ResearchConceptsImage gray level informationGray level informationNeighbor objectsMedical imagesTraining imagesMedical imageryMultiple objectsDeformable modelSynthetic dataLevel informationSegmentationMap shapeEstimation frameworkPrior informationLevel set functionObjectsJoint probability distributionSet functionInformationImagesNovel methodMaximum AJoint density functionProbability distributionFramework
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