2025
Significance of Coronary Artery Calcifications and Ischemic Electrocardiographic Changes Among Patients Undergoing Myocardial Perfusion Imaging
Kokkinidis D, Kyriakoulis I, Chui P, Agarwal R, Liu Y, Khera R, Sinusas A, Velazquez E, Miller E, Feher A. Significance of Coronary Artery Calcifications and Ischemic Electrocardiographic Changes Among Patients Undergoing Myocardial Perfusion Imaging. JACC Advances 2025, 4: 101618. PMID: 39983619, PMCID: PMC11891677, DOI: 10.1016/j.jacadv.2025.101618.Peer-Reviewed Original ResearchCoronary artery calcificationMyocardial perfusion imagingIschemic ECG changesLow event ratesECG changesNormal perfusionArtery calcificationPerfusion imagingSingle-photon emission computed tomography/computed tomographyStress ECGCAC evaluationPresence of coronary artery calcificationSuspected coronary artery diseaseMedian follow-upEvent ratesIschemic electrocardiographic changesAnalysis to patientsComposite endpoint rateCoronary artery diseaseTomography/computed tomographyPrognostic informationMACE rateFollow-upSubgroup analysisAdverse outcomes
2021
Effects of opioid receptor agonist and antagonist medications on electrocardiogram changes and presentation of cardiac arrhythmia: review article
Etaee F, Tobin M, Vuppala S, Komaki A, Delisle B, Di Biase L, Catanzaro J, Natale A, Elayi C. Effects of opioid receptor agonist and antagonist medications on electrocardiogram changes and presentation of cardiac arrhythmia: review article. Journal Of Interventional Cardiac Electrophysiology 2021, 63: 471-500. PMID: 34674120, DOI: 10.1007/s10840-021-01072-1.Peer-Reviewed Original ResearchConceptsCardiac arrhythmiasOpioid medicationsPrescribed opioidsElectrocardiogram changesPrescription opioidsStructural cardiac diseaseProlonged QTc intervalQTc interval prolongationOpioid use disorderAccurate patient selectionOpioid receptor agonistsSignificant side effectsMethodsA literature searchLethal torsadesConcomitant medicationsMaintenance therapyQTc prolongationChronic painInterval prolongationQTc intervalECG changesFatal outcomePatient selectionCardiac toxicityProcedural sedation
2017
Derivation of a Clinical Model to Predict Unchanged Inpatient Echocardiograms
Gunderson CG, Gromisch ES, Chang JJ, Malm BJ. Derivation of a Clinical Model to Predict Unchanged Inpatient Echocardiograms. Journal Of Hospital Medicine 2017, 13: 164-169. PMID: 29073315, DOI: 10.12788/jhm.2866.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseAcute myocardial infarctionCAVE scoreClinical prediction modelKidney diseaseMyocardial infarctionSingle-center retrospective cohort studyRetrospective cohort studyGood discriminationInpatient echocardiogramSubset of studiesCohort studyIndependent predictorsValvular diseaseECG changesElectrocardiogram changesC-statisticCardiothoracic surgeryRepeat studyFull cohortClinical modelDiseaseTTEΒ coefficientsInfarction
2004
Do electrocardiographic changes with adenosine myocardial perfusion imaging predict ischaemia in patients with left ventricular hypertrophy?
Vashist A, Victoria A, Blum S, Bella J, Heller E. Do electrocardiographic changes with adenosine myocardial perfusion imaging predict ischaemia in patients with left ventricular hypertrophy? Nuclear Medicine Communications 2004, 25: 553-556. PMID: 15167513, DOI: 10.1097/01.mnm.0000126630.47661.d9.Peer-Reviewed Original ResearchMeSH KeywordsAdenosineCausalityComorbidityElectrocardiographyExercise TestFemaleHumansHypertrophy, Left VentricularIncidenceMaleMiddle AgedMyocardial IschemiaPrevalencePrognosisRadionuclide ImagingReproducibility of ResultsRetrospective StudiesSensitivity and SpecificityStatistics as TopicUnited StatesConceptsLeft ventricular hypertrophyECG changesVentricular hypertrophyBaseline electrocardiogramElectrocardiographic changesPredictive valueSevere coronary artery diseaseEvidence of ischaemiaCoronary artery diseaseAdenosine myocardial perfusionForm of exercisePresence of collateralsNegative predictive valuePositive predictive valueArtery diseaseConsecutive patientsImaging correlatesTc-sestamibiIschaemiaMyocardial perfusionPatientsX minHypertrophyPerfusionStress test
2003
Prognostic significance of ischemic electrocardiographic changes during adenosine infusion in patients with normal myocardial perfusion imaging
Abbott B, Afshar M, Berger A, Wackers F. Prognostic significance of ischemic electrocardiographic changes during adenosine infusion in patients with normal myocardial perfusion imaging. Journal Of Nuclear Cardiology 2003, 10: 9-16. PMID: 12569326, DOI: 10.1067/mnc.2002.127625.Peer-Reviewed Original ResearchConceptsNormal myocardial perfusion imagingAdenosine myocardial perfusion imagingST-segment depressionMyocardial perfusion imagingIschemic ECG changesCardiac eventsECG changesAdenosine infusionCardiac deathPrognostic significanceECG groupNormal myocardial perfusion imagesBaseline electrocardiographic abnormalitiesAdverse cardiac eventsIschemic electrocardiographic changesNonfatal myocardial infarctionSubsequent cardiac eventsFuture cardiac eventsNormal myocardial perfusionSex-matched groupPerfusion imagesECG evidenceElectrocardiographic abnormalitiesIndependent predictorsElectrocardiographic changes
1993
Gender independence of ambulatory electrocardiographic monitoring in predicting perioperative cardiac risk
Fleisher L, Rosenbaum S, Nelson A, Rosenfeld L. Gender independence of ambulatory electrocardiographic monitoring in predicting perioperative cardiac risk. The American Journal Of Cardiology 1993, 71: 241-242. PMID: 8421990, DOI: 10.1016/0002-9149(93)90745-x.Peer-Reviewed Original ResearchConceptsAmbulatory electrocardiographic monitoringCardiac riskElectrocardiographic monitoringMyocardial ischemiaMorbid cardiac eventsPerioperative cardiac morbidityPerioperative cardiac riskPostoperative myocardial ischemiaHigh-risk patientsCoronary artery diseaseCardiac morbidityNoncardiac surgerySilent ischemiaArtery diseaseCardiac eventsECG changesAmbulatory monitoringMale populationIschemiaWomenStrongest predictorRiskMorbidityPatientsSurgery
1992
ST Segment Depression during Labor and Delivery
Mathew J, Fleisher L, Rinehouse J, Sevarino F, Sinatra R, Nelson A, Prokop E, Rosenbaum S. ST Segment Depression during Labor and Delivery. Anesthesiology 1992, 77: 635-641. PMID: 1416160, DOI: 10.1097/00000542-199210000-00004.Peer-Reviewed Original ResearchConceptsST-segment depressionEjection fraction areaSegment depressionCesarean deliveryVenous air embolismST depressionAir embolismRegional wall motion abnormalitiesContinuous ambulatory ECGST-segment elevationWall motion abnormalitiesPrecordial Doppler monitoringCesarean sectionMyocardial impairmentVaginal deliverySegment elevationGeneral anesthesiaECG changesMotion abnormalitiesMyocardial ischemiaDoppler monitoringRegional anesthesiaST changesEchocardiographic imagingFraction area
1989
Transient left ventricular dysfunction during provocative mental stress in patients with coronary artery disease
LaVeau P, Rozanski A, Krantz D, Cornell C, Cattanach L, Zaret B, Wackers F. Transient left ventricular dysfunction during provocative mental stress in patients with coronary artery disease. American Heart Journal 1989, 118: 1-8. PMID: 2741776, DOI: 10.1016/0002-8703(89)90064-1.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionCoronary artery diseaseCoronary diseaseMental stressArtery diseaseNormal volunteersPsychological stressVentricular ejection fractionStress-induced abnormalitiesLVEF responseChest painVentricular dysfunctionEjection fractionDouble productECG changesTransient ischemiaAcute decreaseBaseline valuesNormal subjectsStroop Color-Word TestPatientsPhysical exerciseAmbulatory monitoringImmediate reboundColor-Word Test
1978
Thallium-201 scintigraphy in unstable angina pectoris.
Wackers F, Lie K, Liem K, Sokole E, Samson G, van der Schoot J, Durrer D. Thallium-201 scintigraphy in unstable angina pectoris. Circulation 1978, 57: 738-742. PMID: 630682, DOI: 10.1161/01.cir.57.4.738.Peer-Reviewed Original ResearchConceptsThallium-201 scintigraphyPain-free periodThallium-201 scansTransient ECG changesPositive scansAbnormal ECGUnstable anginaECG changesGroup IIUnstable angina pectorisFree periodCoronary surgeryAngina pectorisComplicated courseMaximal treatmentPatientsAnginaGroup IScintigraphyECGScansTreatmentPectorisScintiscanInfarction
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