2024
Poster 291: Entry Point-Transition Point Angle as a Novel 3-Dimensional Metric of Patellar Instability
Park N, Sieberer J, Rancu A, Manafzadeh A, McDonald C, Yu K, Wiznia D, Fulkerson J. Poster 291: Entry Point-Transition Point Angle as a Novel 3-Dimensional Metric of Patellar Instability. Orthopaedic Journal Of Sports Medicine 2024, 12: 2325967124s00258. PMCID: PMC11328264, DOI: 10.1177/2325967124s00258.Peer-Reviewed Original ResearchPatellar instabilityComputed tomographyTrochlear dysplasiaGeneral populationRecurrent dislocationDegree of dysplasiaRecurrent patellar dislocationMann-Whitney U testInstitutional review board exemptionDistal femurGeneral population cohortPatellofemoral painPatellar dislocationMann-WhitneyU testCT imagesDysplasiaAnteroposterior viewPatientsTrochlear morphologyInterclass correlationPopulation cohortNew Mexico Decedent Image DatabaseCohortFemurNon-dominant, Lesional Parieto-occipital Lobe Epilepsy
Herlopian A. Non-dominant, Lesional Parieto-occipital Lobe Epilepsy. 2024, 221-240. DOI: 10.1007/978-3-031-23828-4_11.Peer-Reviewed Original ResearchFocal cortical dysplasiaCortical dysplasiaSupratentorial cystic lesionsPost-operative outcomesInterictal epileptiform activityPredictors of outcomeAnti-seizure medicationsMechanisms of epileptogenesisVisual evoked potentialsNeocortical epilepsy surgeryResection surgeryCystic lesionsSurgical interventionEpileptiform activityDifferential diagnosisEvoked potentialsPharmacoresistant epilepsyPatient populationNeuroimaging characteristicsEpilepsy surgeryDysplasiaPatientsOccipital lobeSensorimotor cortexSurgeryNon-dominant, Lesional Frontal Lobe Epilepsy Overlapping with Motor Cortex
Herlopian A. Non-dominant, Lesional Frontal Lobe Epilepsy Overlapping with Motor Cortex. 2024, 469-496. DOI: 10.1007/978-3-031-23828-4_20.Peer-Reviewed Original ResearchFocal cortical dysplasiaCortical dysplasiaIntracranial monitoringPredictors of seizure freedomIctal onset patternsPost-operative outcomesSurgical decision-making processFrontal lobe epilepsySensorimotor functionDysplastic cortexResection marginsSurgical interventionSeizure freedomEpileptiform patternsLobe epilepsyPharmacoresistant epilepsyMotor cortexOnset patternsDysplasiaCortexPatientsCircuit organizationEpileptiformEpilepsyLonger Colonoscopy Withdrawal Time Is Associated With the Detection of Visible Dysplasia in Patients With Inflammatory Bowel Disease
McMillan C, Li D, Mohamed G, Alsadoun D, Almohsen L, Gaidos J, Proctor D, Al-Bawardy B. Longer Colonoscopy Withdrawal Time Is Associated With the Detection of Visible Dysplasia in Patients With Inflammatory Bowel Disease. Crohn's & Colitis 360 2024, 6: otae020. PMID: 38585555, PMCID: PMC10998460, DOI: 10.1093/crocol/otae020.Peer-Reviewed Original ResearchColonoscopy withdrawal timeHigh-definition white light colonoscopyInflammatory bowel diseaseWhite light colonoscopyVisible dysplasiaBowel diseasePersonal historyWithdrawal timeAssociated with detectionEndoscopic healingAdenoma detectionDysplasia detectionDysplasia groupRetrospective studyAdult patientsInvisible dysplasiaColonoscopyPrimary outcomeDysplasiaMultivariate analysisPatientsIncreasing ageGeneral populationMinutesDisease
2023
WATS3D: An Interobserver Study of Barrett's Esophagus–Associated Dysplasia Among Gastrointestinal Pathologists
Patil D, Goldblum J, Lauwers G, Lewis J, Robert M, Singer M, Odze R. WATS3D: An Interobserver Study of Barrett's Esophagus–Associated Dysplasia Among Gastrointestinal Pathologists. Clinical And Translational Gastroenterology 2023, 15: e00661. PMID: 38088399, PMCID: PMC10887448, DOI: 10.14309/ctg.0000000000000661.Peer-Reviewed Original ResearchConceptsBarrett's esophagusGI pathologistsCell blocksWide-area transepithelial samplingDetection rate of dysplasiaBE-associated dysplasiaRate of dysplasiaKappa valuesDetection of neoplasiaGastrointestinal (GILiquid cytologyEvaluate digital imagesSmear specimensGastrointestinal pathologistsInterobserver variabilityIndividual diagnostic categoriesStudy pathologistsInterobserver studyDysplasiaPathologistsCellular fociComputer-assisted analysisDiagnostic categoriesDetection rateTraining sessionsInterdependence in the Cardiorespiratory Network of Preterm Infants with Pulmonary Hypertension Using Mutual Information Analysis
Ramanand P, Indic P, Gentle S, Ambalavanan N. Interdependence in the Cardiorespiratory Network of Preterm Infants with Pulmonary Hypertension Using Mutual Information Analysis. 2016 Computing In Cardiology Conference (CinC) 2023, 50: 1-4. DOI: 10.22489/cinc.2023.354.Peer-Reviewed Original ResearchBronchopulmonary dysplasiaPreterm infantsPulmonary hypertensionCardiorespiratory networkComplications of PHHeart ratePH groupMechanisms of disease progressionRespiratory rateDisease progressionPretermInfantsOxygen saturationCardiorespiratory morbidityHypertensionGroupMean delayDysplasiaComplicationsMorbidityHypophosphatemic rickets: An unexplained early feature of craniometaphyseal dysplasia
Barros J, Braddock D, Carpenter T. Hypophosphatemic rickets: An unexplained early feature of craniometaphyseal dysplasia. Bone Reports 2023, 19: 101707. PMID: 37654679, PMCID: PMC10466911, DOI: 10.1016/j.bonr.2023.101707.Peer-Reviewed Original ResearchMonths of ageCraniometaphyseal dysplasiaLow serum phosphorusElevated serum alkaline phosphatase activityHeterozygous pathogenic variantsSerum alkaline phosphatase activityHigh tubular reabsorptionProgressive hyperostosisSecondary hyperparathyroidismRadiographic improvementSerum phosphorusTubular reabsorptionRadiographic changesCranial nervesEarly featureMetaphyseal flaringPathogenic variantsDysplasiaRicketsSkeletal dysplasiaBiochemical profileMonthsLong bonesCraniofacial bonesAge 1Excitatory somatostatin interneurons in the dentate gyrus drive a widespread seizure network in cortical dysplasia
Zheng Y, Xu C, Sun J, Ming W, Dai S, Shao Y, Qiu X, Li M, Shen C, Xu J, Fei F, Fang J, Jiang X, Zheng G, Hu W, Wang Y, Wang S, Ding M, Chen Z. Excitatory somatostatin interneurons in the dentate gyrus drive a widespread seizure network in cortical dysplasia. Signal Transduction And Targeted Therapy 2023, 8: 186. PMID: 37193687, PMCID: PMC10188524, DOI: 10.1038/s41392-023-01404-9.Peer-Reviewed Original ResearchConceptsSomatostatin-positive interneuronsCortical dysplasiaSeizure networkDentate gyrusParvalbumin-positive interneuronsSomatostatin-positive neuronsExcitatory transmissionDysplastic lesionsSomatostatin interneuronsPoor prognosisSomatostatin-positiveEpileptic hippocampusImmunohistochemical studiesCalcium imagingDysplasiaInterneuronsElectrophysiological recordingsSeizure generalizationCellular basisSeizuresInhibitory roleHippocampusOptogenetic studiesDentateCellular substrates113 LONGER COLONOSCOPY WITHDRAWAL TIME IS ASSOCIATED WITH THE DETECTION OF POLYPOID DYSPLASIA IN INFLAMMATORY BOWEL DISEASE
McMillan C, Li D, Gaidos J, Proctor D, Al Bawardy B. 113 LONGER COLONOSCOPY WITHDRAWAL TIME IS ASSOCIATED WITH THE DETECTION OF POLYPOID DYSPLASIA IN INFLAMMATORY BOWEL DISEASE. Gastroenterology 2023, 164: s-16. DOI: 10.1016/s0016-5085(23)00993-9.Peer-Reviewed Original ResearchThree-Dimensional Reproductions for Surgical Decision-Making in the Treatment of Recurrent Patella Dislocation
Yu K, Beitler B, Cooperman D, Frumberg D, Schneble C, McLaughlin W, Fulkerson J. Three-Dimensional Reproductions for Surgical Decision-Making in the Treatment of Recurrent Patella Dislocation. Arthroscopy Techniques 2023, 12: e807-e811. PMID: 37424639, PMCID: PMC10323671, DOI: 10.1016/j.eats.2023.02.010.Peer-Reviewed Original ResearchRecurrent patella dislocationPatellofemoral jointPatella dislocationTrochlea dysplasiaSurgical decisionPatellofemoral instabilityJoint stabilityPatellar trackingOsseous factorsComplex anatomyDysplasiaSurgical planningFemoral trochleaSoft tissuePatientsTreatmentThree-dimensional reproductionClassification systemSurgical
2022
A review and guide to nutritional care of the infant with established bronchopulmonary dysplasia
Miller A, Curtiss J, Taylor S, Backes C, Kielt M. A review and guide to nutritional care of the infant with established bronchopulmonary dysplasia. Journal Of Perinatology 2022, 43: 402-410. PMID: 36494567, DOI: 10.1038/s41372-022-01578-0.Peer-Reviewed Original ResearchConceptsBronchopulmonary dysplasiaNutritional careCommon long-term morbidityIncidence of BPDLong-term pulmonary functionEnteral nutrition managementLong-term morbidityExcess weight gainPostnatal growth failureBPD preventionPreterm nutritionPulmonary functionNeurodevelopmental outcomesPremature birthChronic diseasesFavorable outcomeLung growthGrowth failureHigh riskClinical experienceComprehensive centerInfantsWeight gainNutrition managementDysplasiaMildly dysplastic oral lesions with optically-detectable abnormalities share genetic similarities with severely dysplastic lesions
Brenes D, Nipper A, Tan M, Gleber-Netto F, Schwarz R, Pickering C, Williams M, Vigneswaran N, Gillenwater A, Sikora A, Richards-Kortum R. Mildly dysplastic oral lesions with optically-detectable abnormalities share genetic similarities with severely dysplastic lesions. Oral Oncology 2022, 135: 106232. PMID: 36335817, PMCID: PMC9881670, DOI: 10.1016/j.oraloncology.2022.106232.Peer-Reviewed Original ResearchConceptsOral premalignant lesionsMild dysplasiaSevere dysplasiaOral lesionsPremalignant lesionsDysplastic oral lesionsHigh-grade pathologySubset of lesionsLoss of autofluorescenceDysplastic lesionsOptical imaging studiesOral surgeryDysplasiaDetectable abnormalitiesPatient careLesionsImaging studiesEpithelial cell nucleiPatientsGene expressionGene expression profilesMarkersGene expression analysisSimilar gene expressionExpression profilesReconceptualization of Trochlear Dysplasia in Patients With Recurrent Patellar Dislocation Using 3-Dimensional Models
Yu K, Cooperman D, Schneble C, McLaughlin W, Beitler B, Kaliney R, Wang A, Fulkerson J. Reconceptualization of Trochlear Dysplasia in Patients With Recurrent Patellar Dislocation Using 3-Dimensional Models. Orthopaedic Journal Of Sports Medicine 2022, 10: 23259671221138257. PMID: 36458105, PMCID: PMC9706073, DOI: 10.1177/23259671221138257.Peer-Reviewed Original ResearchRecurrent patellar dislocationPatellar dislocationTrochlear dysplasiaProximal trochleaTomography scanControl kneesTrochlear grooveFemoral condyleHealthy control kneesIntercondylar notch roofProximal trochlear grooveComputed tomography scanCross-sectional studyLevel of evidenceDistal femoral condylePosterior femoral condylesLateral trochlear ridgeNotch roofMediolateral positioningNovel 3D measurement methodPatientsKneeDysplasiaSurgical planningOsseous anatomySepto-optic dysplasia in an infant
Aliu E, Musa J, Parisapogu A, Kola E, Hyseni F, Kola I, Blandón A, Roy P, Prathima K, Banavath C, Kumbha P, Tappa S, Saini J, Pichuthirumalai S, Ahmetgjekaj I. Septo-optic dysplasia in an infant. Radiology Case Reports 2022, 17: 3147-3150. PMID: 35801123, PMCID: PMC9253040, DOI: 10.1016/j.radcr.2022.06.002.Peer-Reviewed Original ResearchSepto-optic dysplasiaSOD patientsAcute respiratory distress syndromeRare congenital anomalyEpisode of acute respiratory distress syndromeRespiratory distress syndromeHypothalamic-pituitary axisMidline brain structuresFollow-up approachClinical presentationCongenital anomaliesDistress syndromeOptic nerveEndocrine abnormalitiesLive birthsManagement modalitiesCongenital disorderPatientsHypoplasiaMultidisciplinary approachDysplasiaBrain structuresDiseasePresentationAgenesisCurrent Review in Basic Science: Animal Models of Focal Cortical Dysplasia and Epilepsy
Nguyen LH, Bordey A. Current Review in Basic Science: Animal Models of Focal Cortical Dysplasia and Epilepsy. Epilepsy Currents 2022, 22: 234-240. PMID: 36187145, PMCID: PMC9483763, DOI: 10.1177/15357597221098230.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsFocal cortical dysplasiaFCD type IIAnimal modelsCortical dysplasiaMechanisms of epileptogenesisNumerous animal modelsElectroclinical featuresIntractable epilepsyType IIFCD subtypesFrequent causeCortical developmentPrevalent causeNovel therapeuticsEpilepsyEarly lifeGene mutationsClinical applicationCurrent reviewDysplasiaTechnical considerationsMTORBasic scienceCauseCommentary on “compatibility of rapid enteral feeding advances and noninvasive ventilation in preterm infants—an observational study”
Buck CO, Taylor SN. Commentary on “compatibility of rapid enteral feeding advances and noninvasive ventilation in preterm infants—an observational study”. Pediatric Pulmonology 2022, 57: 1113-1116. PMID: 35191225, DOI: 10.1002/ppul.25867.Peer-Reviewed Original ResearchConceptsExtremely preterm infantsPreterm infantsBronchopulmonary dysplasiaRapid enteral feeding advancementEnteral feeding advancementFull enteral feedingVery preterm infantsFeeding advanceFeeding advancementEnteral feedingMultifactorial pathogenesisNoninvasive ventilationNutritional supportCritical careObservational studyInfantsPotential rolePotential benefitsDysplasiaPathogenesisCareDuration of noninvasive respiratory support and risk for bronchopulmonary dysplasia or death
Gentle S, Carper B, Laughon M, Jensen E, Williams A, Travers C, Ambalavanan N, Lal C, Carlo W. Duration of noninvasive respiratory support and risk for bronchopulmonary dysplasia or death. Journal Of Perinatology 2022, 42: 454-460. PMID: 35034096, PMCID: PMC9007818, DOI: 10.1038/s41372-021-01269-2.Peer-Reviewed Original ResearchConceptsNoninvasive respiratory supportDuration of noninvasive respiratory supportBronchopulmonary dysplasiaRespiratory supportAssociated with bronchopulmonary dysplasiaDevelopment of bronchopulmonary dysplasiaRetrospective study of infantsStudy of infantsPreterm infantsWeeks gestationPropensity score matchingNoninvasive supportMedian durationRetrospective studyPotential confoundersIllness severityScore matchingInfantsPropensity scoreGestationDysplasiaDeathDurationAssociationPretermComplex Total Hip Arthroplasty in a Patient with Klippel-Trénaunay Syndrome
Morrison T, Streufert B, Engel C, Bernasek T, Gill M. Complex Total Hip Arthroplasty in a Patient with Klippel-Trénaunay Syndrome. JBJS Case Connector 2022, 12: e20.00488. PMID: 35020676, DOI: 10.2106/jbjs.cc.20.00488.Peer-Reviewed Original ResearchConceptsKlippel-Trenaunay syndromeAssociated with Klippel-Trenaunay syndromeTotal hip arthroplastyMultidisciplinary perioperative approachPreoperative embolizationCases of hip dysplasiaIntraoperative angiographyVascular malformationsPerioperative approachOcclusion balloonDysplasiaHip arthroplastyKlippel-Trenaunay
2021
Endoscopic Shelf Procedure and Ischiofemoral Decompression with Arthroscopic Acetabular Labral Reconstruction
Maldonado DR, Owens JS, Jimenez AE, Saks BR, Lall AC, Domb BG. Endoscopic Shelf Procedure and Ischiofemoral Decompression with Arthroscopic Acetabular Labral Reconstruction. JBJS Case Connector 2021, 11: e21.00329. PMID: 34762605, DOI: 10.2106/jbjs.cc.21.00329.Peer-Reviewed Case Reports and Technical NotesConceptsCam-type morphologyIrreparable labral tearsLabral tearsLabral reconstructionIschiofemoral impingementHip endoscopyHip arthroscopyShelf procedureYoung adult patientsArthroscopic acetabular labral reconstructionAcetabular labral reconstructionAdult patientsFemale patientsCase reportFavorable outcomeRight hipIFI diagnosisHip dysplasiaPatientsTearsDecompressionDysplasiaEndoscopyArthroscopyDiagnosisShort-term patient-reported outcomes following concomitant hip arthroscopy and the endoscopic modified shelf procedure for the treatment of acetabular dysplasia and intra-articular pathology
Maldonado DR, Owens JS, Ouyang VW, Saks BR, Jimenez AE, Glein RM, Lall AC, Domb BG. Short-term patient-reported outcomes following concomitant hip arthroscopy and the endoscopic modified shelf procedure for the treatment of acetabular dysplasia and intra-articular pathology. Journal Of Hip Preservation Surgery 2021, 8: 105-118. PMID: 34567605, PMCID: PMC8460173, DOI: 10.1093/jhps/hnab044.Peer-Reviewed Original ResearchPatient-reported outcomesConcomitant hip arthroscopyShort-term patient-reported outcomesCenter-edge angleAcetabular dysplasiaHip arthroscopyShelf procedureLabral tearsLateral center-edge angleSelective surgical indicationsIntra-articular pathologySurgical indicationsMean ageSecondary surgeryAcetabular coverageFavorable outcomeInvasive alternativeEndoscopic proceduresTönnis angleAlpha angleDysplasiaArthroscopyEndoscopicEffective procedureOutcomes
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