2024
Mechanical clot disruption during pulmonary thromboembolectomy is safe: A propensity score-matched analysis
Thomas S, Deshmukh A, Mojibian H, Marino A, Lozada J, Cornman-Homonoff J. Mechanical clot disruption during pulmonary thromboembolectomy is safe: A propensity score-matched analysis. Clinical Imaging 2024, 118: 110381. PMID: 39637758, DOI: 10.1016/j.clinimag.2024.110381.Peer-Reviewed Original ResearchPulmonary thromboembolectomyPulmonary emboliPulmonary arteryRight pulmonary arteryLeft pulmonary arteryPulmonary artery pressureAdministration of anticoagulantsDuration of hospitalizationMechanical clot disruptionPropensity-score matchingSPESI scorePulmonary vasculatureArterial pressureClinical effectsOrganized thrombusThromboembolectomyPropensity-scoreClot disruptionInclusion criteriaPatientsMortality rateRisk categoriesCompare groupsStudy periodArteryEffects of Buprenorphine, Methadone, and Substance Use on COVID-19 Morbidity and Mortality
Christian N, Zhou X, Radhakrishnan R. Effects of Buprenorphine, Methadone, and Substance Use on COVID-19 Morbidity and Mortality. Journal Of Addiction Medicine 2024, 19: 223-226. PMID: 39475125, DOI: 10.1097/adm.0000000000001386.Peer-Reviewed Original ResearchConceptsActive substance useSubstance useAssociated with increased morbidityDuration of hospitalizationCOVID-19 outcomesOpioid useSubstance use disordersImpact of substance useCOVID-19 infectionEffects of buprenorphineOpioid use disorderRetrospective cohort studyUse disorderAll-cause mortalityCOVID-19 positive patientsUrine toxicologyMultivariate logistic regressionAssociated with statistically significant increasesMedical comorbidityStatistically significant differenceMOUD treatmentStatistically significant increaseAssociated with worse COVID-19 outcomesCOVID-19 morbidityUrban hospital system
2023
The effect of duration of untreated psychosis (DUP) on the risk for hospitalization after admission to a first episode service
Ferrara M, Guloksuz S, Hazan H, Li F, Tek C, Sykes L, Riley S, Keshavan M, Srihari V. The effect of duration of untreated psychosis (DUP) on the risk for hospitalization after admission to a first episode service. Schizophrenia Research 2023, 260: 198-204. PMID: 37688984, DOI: 10.1016/j.schres.2023.08.005.Peer-Reviewed Original ResearchConceptsFirst-episode psychosis servicesLength of stayUntreated psychosisPsychiatric hospitalizationFirst-episode servicesDuration of hospitalizationIncidence rate ratiosNon-affective psychosisNew Haven areaPoisson regression modelsPatient characteristicsHospitalization ratesRecent onsetMedical recordsHospitalizationEffect of durationNegative binomial regressionSpecialized treatmentPsychosisRate ratioBinomial regressionAdmissionDUPEnrollmentFirst year
2022
Comparing Three Wearable Accelerometers to Measure Early Activity after Cardiac Surgery
Brown C, Yanek L, Healy R, Tsay T, Di J, Goeddel L, Young D, Zipunnikov V, Schrack J, Group C, Whitman G, Mandal K, Madeira T, Grant M, Hoyer E. Comparing Three Wearable Accelerometers to Measure Early Activity after Cardiac Surgery. JTCVS Open 2022, 11: 176-191. PMID: 36172447, PMCID: PMC9510817, DOI: 10.1016/j.xjon.2022.05.011.Peer-Reviewed Original ResearchHospital-based outcomesCardiac surgeryWearable activity monitorsPrimary outcomeNonhome locationActivity monitorCardiac surgery patientsDuration of hospitalizationSteps/dayAccelerometry monitorsClinical characteristicsCohort studySurgery patientsPostoperative activityProlonged hospitalizationWearable accelerometersPatient riskMobility ScaleSpectrum of characteristicsPatientsSurgeryAdditive valueOutcomesHospitalizationReadmissionInternational guidelines regarding the role of IVIG in the management of Rh‐ and ABO‐mediated haemolytic disease of the newborn
Lieberman L, Lopriore E, Baker JM, Bercovitz RS, Christensen RD, Crighton G, Delaney M, Goel R, Hendrickson JE, Keir A, Landry D, La Rocca U, Lemyre B, Maier RF, Muniz‐Diaz E, Nahirniak S, New HV, Pavenski K, dos Santos M, Ramsey G, Shehata N, Guidelines F. International guidelines regarding the role of IVIG in the management of Rh‐ and ABO‐mediated haemolytic disease of the newborn. British Journal Of Haematology 2022, 198: 183-195. PMID: 35415922, PMCID: PMC9324942, DOI: 10.1111/bjh.18170.Peer-Reviewed Original ResearchConceptsRole of IVIGIntravenous immunoglobulinExchange transfusionHaemolytic diseaseSafety of IVIGRed blood cell transfusionBlood cell transfusionDuration of hospitalizationSeverity of anemiaEvidence-based recommendationsHigh-quality studiesCell transfusionPrompt treatmentBilirubin levelsSignificant morbidityAlternative therapiesIntensive phototherapyNeurocognitive outcomesManagement of RhInternational guidelinesTransfusionNewbornsDiseasePhototherapyInternational panel
2018
Clinical Features and Outcomes of Immunocompromised Children Hospitalized With Laboratory-Confirmed Influenza in the United States, 2011–2015
Collins JP, Campbell AP, Openo K, Farley MM, Cummings CN, Kirley PD, Herlihy R, Yousey-Hindes K, Monroe ML, Ladisky M, Lynfield R, Baumbach J, Spina N, Bennett N, Billing L, Thomas A, Schaffner W, Price A, Garg S, Anderson EJ. Clinical Features and Outcomes of Immunocompromised Children Hospitalized With Laboratory-Confirmed Influenza in the United States, 2011–2015. Journal Of The Pediatric Infectious Diseases Society 2018, 8: 539-549. PMID: 30358877, DOI: 10.1093/jpids/piy101.Peer-Reviewed Original ResearchConceptsSolid organ transplantationImmunocompromised childrenClinical featuresImmunosuppressive therapyIntensive careOrgan transplantationInfluenza Hospitalization Surveillance NetworkHuman immunodeficiency virus/Community-acquired influenzaEarly antiviral treatmentLonger hospitalization durationDuration of hospitalizationIntensive care admissionAntiviral useCare admissionHospital deathHospitalization durationInfluenza vaccinationAntiviral treatmentInfluenza seasonInfluenza severityPrimary outcomeImmunodeficiency syndromeMultivariable analysisImmunoglobulin deficiency
2011
Postlobectomy Chest Radiographic Changes: A Quantitative Analysis
Kim C, Godelman A, Jain V, Merav A, Haramati L. Postlobectomy Chest Radiographic Changes: A Quantitative Analysis. Canadian Association Of Radiologists Journal 2011, 62: 280-287. PMID: 21958743, DOI: 10.1016/j.carj.2010.12.005.Peer-Reviewed Original ResearchConceptsAir leak durationPrior sternotomyMediastinal shiftRadiographic changesChest radiographsRetrospective case-control seriesDuration of hospitalizationPostoperative chest radiographsChest radiographic changesPresence of pneumothoraxCase-control seriesRatio of postSubsequent lobectomyHospital staySurgical complicationsComplication rateConsecutive patientsRadiographic findingsHemidiaphragm elevationPreoperative measurementsPatient outcomesAir leakLobectomy siteLobectomySternotomyAudit and feedback: An intervention to improve discharge summary completion
Dinescu A, Fernandez H, Ross JS, Karani R. Audit and feedback: An intervention to improve discharge summary completion. Journal Of Hospital Medicine 2011, 6: 28-32. PMID: 21241038, PMCID: PMC3102562, DOI: 10.1002/jhm.831.Peer-Reviewed Original ResearchConceptsDischarge summariesDuration of hospitalizationPost-intervention studyDischarge summary completionFirst-year fellowsImportant clinical informationGeriatric medicine fellowsAdverse eventsDischarge planningOutpatient settingClinical informationYear fellowsGeriatric careIntervention studiesSame checklistFeedback sessionsPerformance scoresPhase 2Feedback interventionPhase 1InterventionIndividual performance scoresAuditChecklistRehospitalization
2010
Randomized Trial of Urgent vs. Elective Colonoscopy in Patients Hospitalized With Lower GI Bleeding
Laine L, Shah A. Randomized Trial of Urgent vs. Elective Colonoscopy in Patients Hospitalized With Lower GI Bleeding. The American Journal Of Gastroenterology 2010, 105: 2636. PMID: 20648004, DOI: 10.1038/ajg.2010.277.Peer-Reviewed Original ResearchConceptsLower GI bleedingElective colonoscopyUpper endoscopyUrgent colonoscopyGI bleedingBlood pressureHeart rateUpper gastrointestinal sourceUpper GI sourceUrgent upper endoscopyPrimary end pointDuration of hospitalizationSystolic blood pressureUnits of bloodEligible patientsUrgent groupElective groupHospital daysOrthostatic changesBlood transfusionClinical outcomesRandomized trialsHospital chargesVs. 5Gastrointestinal source
2007
Generalized convulsive status epilepticus after nontraumatic subarachnoid hemorrhage: the nationwide inpatient sample.
Claassen J, Bateman BT, Willey JZ, Inati S, Hirsch LJ, Mayer SA, Sacco RL, Schumacher HC. Generalized convulsive status epilepticus after nontraumatic subarachnoid hemorrhage: the nationwide inpatient sample. Neurosurgery 2007, 61: 60-4; discussion 64-5. PMID: 17621019, DOI: 10.1227/01.neu.0000279724.05898.e7.Peer-Reviewed Original ResearchConceptsNontraumatic subarachnoid hemorrhageConvulsive status epilepticusNationwide Inpatient SampleSubarachnoid hemorrhageRenal diseaseStatus epilepticusInpatient SampleNonfederal United States hospitalsGeneralized convulsive status epilepticusDatabase of admissionsDuration of hospitalizationMultivariate logistic regressionUnited States hospitalsHospital mortalityHospital stayAdult patientsYounger patientsIndependent predictorsPatient mortalityEmergency departmentPatientsLinear regression analysisState HospitalNeurosurgical proceduresLogistic regression
2000
Transplantation of CD34+ peripheral blood cells selected using a fully automated immunomagnetic system in patients with high-risk breast cancer: results of a prospective randomized multicenter clinical trial
Yanovich S, Mitsky P, Cornetta K, Maziarz R, Rosenfeld C, Krause D, Lotz J, Bitran J, Williams S, Preti R, Somlo G, Burtness B, Mills B. Transplantation of CD34+ peripheral blood cells selected using a fully automated immunomagnetic system in patients with high-risk breast cancer: results of a prospective randomized multicenter clinical trial. Bone Marrow Transplantation 2000, 25: 1165-1174. PMID: 10849529, DOI: 10.1038/sj.bmt.1702415.Peer-Reviewed Original ResearchConceptsHigh-risk breast cancer patientsBreast cancer patientsMedian timeCancer patientsIsolated CD34Clinical trialsCell selection systemHematopoietic reconstitutionHigh-risk breast cancerCapacity of CD34Transplantation of CD34Absolute neutrophil countDuration of hospitalizationHigh-dose chemotherapyMulticenter clinical trialBone Marrow Transplantation (2000) 25Incidence of infectionPeripheral blood cellsInter-group differencesProgenitor cell graftsPlatelet engraftmentNeutrophil countCell transplantPlatelet transfusionsPlatelet count
1999
Increasing incidence of Gram-negative rod bacteremia in a newborn intensive care unit
SHAH S, EHRENKRANZ R, GALLAGHER P. Increasing incidence of Gram-negative rod bacteremia in a newborn intensive care unit. The Pediatric Infectious Disease Journal 1999, 18: 591-595. PMID: 10440433, DOI: 10.1097/00006454-199907000-00005.Peer-Reviewed Original ResearchConceptsGNR bacteremiaCare unitNewborn Special Care UnitPercutaneous central venous cathetersNewborn intensive care unitYale-New Haven HospitalMaternal intrapartum antibioticsGram-negative rod bacteremiaDuration of hospitalizationCentral venous cathetersNegative rod bacteremiaIntensive care unitStepwise multivariate analysisSpecial care unitsNumber of admissionsIntrapartum antibioticsVenous cathetersRetrospective reviewOverall incidenceNeonatal careProspective studyPatient populationBacteremiaMultivariate analysisIncidence
1998
Very low birth weight outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, January 1993 through December 1994
Stevenson D, Wright L, Lemons J, Oh W, Korones S, Papile L, Bauer C, Stoll B, Tyson J, Shankaran S, Fanaroff A, Donovan E, Ehrenkranz R, Verter J. Very low birth weight outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, January 1993 through December 1994. American Journal Of Obstetrics And Gynecology 1998, 179: 1632-1639. PMID: 9855609, DOI: 10.1016/s0002-9378(98)70037-7.Peer-Reviewed Original ResearchConceptsHuman Development Neonatal Research NetworkNeonatal Research NetworkNational Institute of Child HealthInstitute of Child HealthDays of lifeGestational ageBirth weightEvidence of intracranial hemorrhageLow birth weight outcomesAverage duration of hospitalizationMortality rateRespiratory distress syndromeChronic lung diseaseDuration of hospitalizationBirth weight outcomesLength of stayNeonatal coursePeriventricular leukomalaciaPerinatal dataIntracranial hemorrhageDistress syndromePerinatal eventsFemale infantAverage length of stayMorbidity rateNosocomial Candida glabrata Colonization: an Epidemiologic Study
Vazquez J, Dembry L, Sanchez V, Vazquez M, Sobel J, Dmuchowski C, Zervos M. Nosocomial Candida glabrata Colonization: an Epidemiologic Study. Journal Of Clinical Microbiology 1998, 36: 421-426. PMID: 9466752, PMCID: PMC104553, DOI: 10.1128/jcm.36.2.421-426.1998.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBone Marrow TransplantationCandidaCandidiasisChildChild, PreschoolCross InfectionDNA, FungalEnvironmental MicrobiologyFemaleHandHealth PersonnelHospitalizationHospitals, UniversityHumansIntensive Care UnitsMaleMiddle AgedMolecular EpidemiologyPolymorphism, Restriction Fragment LengthProspective StudiesRisk FactorsConceptsNosocomial acquisitionC. glabrataMedical intensive care unitBone marrow transplant unitPrior antimicrobial useDuration of hospitalizationIntensive care unitMarrow transplant unitSignificant risk factorsImportant nosocomial pathogenStrain typesSame strain typeCare unitTransplant unitUniversity HospitalRisk factorsEpidemiologic studiesPatientsC. glabrata strainsEnvironmental surfacesHospital personnelNosocomial pathogenAntimicrobial useIdentical strainsHospital environment
1992
Neonatal correction of transposition of the great arteries: the Connecticut experience.
Dewar ML, Kleinman C, Hellenbrand W, Fahey J, Talner N, Brueckner M, Kopf GS. Neonatal correction of transposition of the great arteries: the Connecticut experience. Connecticut Medicine 1992, 56: 671-4. PMID: 1288934.Peer-Reviewed Original ResearchConceptsGreat arteriesAtrial levelSurgical approachNormal anatomyCommon congenital cardiac defectArterial switch patientsAtrial level repairNormal ventricular functionDuration of hospitalizationProcedure of choiceCongenital cardiac defectsTreatment of transpositionNormal sinus rhythmNeonatal correctionSwitch patientsOperative mortalityPulmonary stenosisVentricular functionIntensive careSinus rhythmCardiac defectsPatientsConnecticut experienceArterySignificant increase
1986
Candidal Suppurative Peripheral Thrombophlebitis Recognition, Prevention, and Management
Walsh T, Bustamente C, Vlahov D, Standiford H. Candidal Suppurative Peripheral Thrombophlebitis Recognition, Prevention, and Management. Infection Control And Hospital Epidemiology 1986, 7: 16-22. PMID: 3633240, DOI: 10.1017/s0195941700063736.Peer-Reviewed Original ResearchConceptsPeripheral thrombophlebitisBroad-spectrum antibiotic therapyCatheter site careSegmental venous resectionIntravenous amphotericin BDuration of hospitalizationCandida speciesAcute care hospitalsNosocomial fungal infectionsSuppurative thrombophlebitisVenous resectionCatheter siteAntibiotic therapyPalpable cordRisk factorsSite careCandidal colonizationRational therapyPatientsAmphotericin BBacterial infectionsThrombophlebitisFungal infectionsTherapyInfection
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