2025
Validación experimental de la gravedad de la estenosis coronaria y el desarrollo de miocardio isquémico
Lee J, Lee S, Kwon W, Kim H, Hong D, Kim H, Cho S, Shin D, Park K, Kim J, Moon J, Song H, Lee S, Ha D, Jang J, Ahn Y, Jeong M, Choi K, Park T, Yang J, Bin Song Y, Hahn J, Choi S, Gwon H, Hong Y. Validación experimental de la gravedad de la estenosis coronaria y el desarrollo de miocardio isquémico. Revista Española De Cardiología 2025, 78: 521-532. DOI: 10.1016/j.recesp.2024.10.006.Peer-Reviewed Original ResearchStress perfusion defectsFractional flow reservePositron emission tomographyLeft anterior descending arteryHemodynamically significant stenosisAnterior descending arteryPerfusion defectsVascular occluderNecrotic myocardiumSignificant stenosisDescending arteryTTC stainingSignificantly higher areaMedian diameter stenosisExperimental animal modelsCoronary artery stenosisHyperemic stenosis resistanceOccluder implantationArtery stenosisDiameter stenosisFlow reserveAnimal modelsStenosisCoronary stenosisOcclusion severityMachine learning and computational fluid dynamics derived FFRCT demonstrate comparable diagnostic performance in patients with coronary artery disease; A Systematic Review and Meta-Analysis
Narimani-Javid R, Moradi M, Mahalleh M, Najafi-Vosough R, Arzhangzadeh A, Khalique O, Mojibian H, Kuno T, Mohsen A, Alam M, Shafiei S, Khansari N, Shaghaghi Z, Nozhat S, Hosseini K, Hosseini S. Machine learning and computational fluid dynamics derived FFRCT demonstrate comparable diagnostic performance in patients with coronary artery disease; A Systematic Review and Meta-Analysis. Journal Of Cardiovascular Computed Tomography 2025, 19: 232-246. PMID: 39988511, DOI: 10.1016/j.jcct.2025.02.004.Peer-Reviewed Original ResearchArea under the curveDiagnostic odds ratioDiagnostic performanceComputed tomography-derived fractional flow reserveDiagnostic performance of FFRCTHemodynamically significant coronary artery stenosisSignificant coronary artery stenosisMeta-analysisPer-patient levelReceiver operating characteristic curveCoronary artery diseaseCoronary artery stenosisPer-vessel levelFractional flow reserveNoninvasive diagnostic techniquesMachine learningInvasive FFRPooled specificityArtery diseaseArtery stenosisFlow reserveOdds ratioCochrane LibraryFFRCTPatients
2024
Experimental validation of coronary stenosis severity and development of ischemic myocardium
Lee J, Lee S, Kwon W, Kim H, Hong D, Kim H, Cho S, Shin D, Park K, Kim J, Moon J, Song H, Lee S, Ha D, Jang J, Ahn Y, Jeong M, Choi K, Park T, Yang J, Song Y, Hahn J, Choi S, Gwon H, Hong Y. Experimental validation of coronary stenosis severity and development of ischemic myocardium. Revista Española De Cardiología (English Edition) 2024, 78: 521-532. PMID: 39490529, DOI: 10.1016/j.rec.2024.10.006.Peer-Reviewed Original ResearchStress perfusion defectsFractional flow reserveLeft anterior descending arteryHemodynamically significant stenosisAnterior descending arteryPerfusion defectsVascular occluderNecrotic myocardiumSignificant stenosisDescending arteryTTC stainingIschemic myocardiumStenosis severitySignificantly higher areaMedian diameter stenosisExperimental animal modelsCoronary artery stenosisCoronary stenosis severityHyperemic stenosis resistanceOccluder implantationArtery stenosisDiameter stenosisFlow reserveAnimal modelsStenosisImpact of ultra-high-resolution on cardiac CT assessment of coronary artery stenoses, plaque burden/composition, and pericoronary adipose tissue attenuation
Matuck B, Latina J, Shabani M, Hoballah M, Mattheson M, Ostovaneh A, Abdollahi A, Ebrahimihoor E, Trost J, Mahesh M, Lima J, Arbab-Zadeh A. Impact of ultra-high-resolution on cardiac CT assessment of coronary artery stenoses, plaque burden/composition, and pericoronary adipose tissue attenuation. European Heart Journal 2024, 45: ehae666.207. DOI: 10.1093/eurheartj/ehae666.207.Peer-Reviewed Original ResearchConventional CCTAPericoronary adipose tissue attenuationAdipose tissue attenuationPlaque volumeUHR-CTPericoronary adipose tissue attenuation valuesCoronary artery plaque volumeCoronary computed tomography angiographyHigh-risk plaque featuresHigher coronary calcium scoresFibrous plaque volumeNon-stented patientsInvasive coronary angiographyCoronary calcium scoreAssessment of coronary artery stenosisPlaque compositionCut-off valueTissue attenuationCoronary artery stenosisMinimal lumen areaAIDR 3DObstructive CADCT attenuationAgatston scoreCalcium scoreAssociation between 82Rb positron emission tomography-derived regional myocardial blood flow, severity of angiographic coronary artery stenosis, and mortality in patients with chest pain
Gallegos C, Paredes C, Hu J, Posada E, Saito Y, Lansky A, Shah S, Liu Y, Smolderen K, Mena-Hurtado C, Sinusas A, Miller E. Association between 82Rb positron emission tomography-derived regional myocardial blood flow, severity of angiographic coronary artery stenosis, and mortality in patients with chest pain. Advances In Radiotherapy & Nuclear Medicine 2024, 2: 3786. DOI: 10.36922/arnm.3786.Peer-Reviewed Original ResearchMyocardial flow reserveGlobal myocardial flow reserveQuantitative coronary angiographyAssociated with increased all-cause mortalityPositron emission tomographyCoronary artery stenosis severityMyocardial blood flowAll-cause mortalityCoronary angiographyChest painStenosis severityAngiographic coronary artery stenosisResting myocardial blood flowAcute chest painBlood flowInvasive coronary angiographyLeft circumflex arteryLeft descending arteryRight coronary arteryCoronary artery stenosisStress testCoronary stenosis severityCardiovascular eventsDescending arteryWeak correlationPulmonary embolism with thrombus in transit across a patent foramen ovale
Iyengar S, Stolear A, Dulgher M, Ahmed A, Shkolnik E, Zarich S. Pulmonary embolism with thrombus in transit across a patent foramen ovale. Oxford Medical Case Reports 2024, 2024: omae091. PMID: 39184868, PMCID: PMC11343825, DOI: 10.1093/omcr/omae091.Peer-Reviewed Original ResearchPatent foramen ovalePatent foramen ovale closureImpending paradoxical embolismPulmonary embolismForamen ovaleCritical left anterior descending coronary artery stenosisObstructive sleep apneaCoronary artery bypass graftingOptimal treatment strategySaddle pulmonary embolusAbsence of standard guidelinesDeep vein thrombosisArtery bypass graftingLife-threatening conditionCoronary artery stenosisSleep apneaTransesophageal echocardiogramPulmonary emboliSurgical thrombectomyVein thrombosisDiagnostic challengeSurgical interventionRight atriumThrombolytic therapyBypass graftingImpact Of Ultra-high-resolution On Cardiac CT Assessment Of Coronary Artery Stenoses, Plaque Burden/composition, And Pericoronary Adipose Tissue Attenuation
Matuck B, Matheson M, Latina J, Shabani M, Hoballah M, Ostovaneh A, Abdollahi A, Ebrahimihoor E, Trost J, Mashes M, Lima J, Arbab-Zadeh A. Impact Of Ultra-high-resolution On Cardiac CT Assessment Of Coronary Artery Stenoses, Plaque Burden/composition, And Pericoronary Adipose Tissue Attenuation. Journal Of Cardiovascular Computed Tomography 2024, 18: s67-s68. DOI: 10.1016/j.jcct.2024.05.159.Peer-Reviewed Original Research
2023
The imPAct of Trimetazidine on MicrOcirculation after Stenting for stable coronary artery disease (PATMOS study)
Ilic I, Timcic S, Milosevic M, Boskovic S, Odanovic N, Furtula M, Dobric M, Aleksandric S, Otasevic P. The imPAct of Trimetazidine on MicrOcirculation after Stenting for stable coronary artery disease (PATMOS study). Frontiers In Cardiovascular Medicine 2023, 10: 1112198. PMID: 37456821, PMCID: PMC10348888, DOI: 10.3389/fcvm.2023.1112198.Peer-Reviewed Original ResearchIndex of microcirculatory resistanceIndex of microcirculatory resistance valuesPercutaneous coronary interventionFractional flow reserveCoronary flow reserveElective percutaneous coronary interventionFractional flow reserve valuesEffect of trimetazidineStandard therapyPrior to elective percutaneous coronary interventionTrimetazidine groupMicrocirculatory resistanceFlow reserveCompared to standard therapyStable coronary artery diseaseProtective effect of trimetazidineEpicardial coronary artery stenosisCoronary artery diseaseCoronary artery lesionsNative coronary artery lesionsCoronary artery stenosisImpact of trimetazidinePromotes glucose oxidationReduced myocardial injuryRisk profile
2022
Coronary artery disease and revascularization associated with immune checkpoint blocker myocarditis: Report from an international registry
Nowatzke J, Guedeney P, Palaskas N, Lehmann L, Ederhy S, Zhu H, Cautela J, Francis S, Courand PY, Deswal A, Ewer SM, Aras M, Arangalage D, Ghafourian K, Fenioux C, Finke D, Peretto G, Zaha V, Zadok O, Tajiri K, Akhter N, Levenson J, Baldassarre L, Power J, Huang S, Collet JP, Moslehi J, Salem JE, contributors I, Aghel N, Alexandre J, Aonuma K, Asnani A, Behling J, Bilen M, Bottinor W, Cariou E, Chahine J, Chan W, Chauhan A, Cohen M, Crusz S, Fernando S, Florido R, Frigeri M, Fukushima S, Gaughan E, Geisler B, Gilstrap L, Grohe C, Guha A, Habib M, Haegler-Laube E, Haydon A, Hayek S, Hughes A, Imai R, Katsume Y, Kimura H, Lin L, Lenneman C, Leong D, Makker V, Martinez-Calle N, Moey M, Mohri M, Morimoto R, Moritoki Y, Narezkina A, Nicol M, Nooka A, Orimoloye O, Patel M, Perl M, Piriou N, Raikhelkar J, Raza Y, Rao A, Reddy S, Seki N, Stangl K, Stewart A, Stringer B, Tamarappoo B, Tamura Y, Thuny F, Tierney S, Tresorier R, Ullah W, Von Hunolstein J, Warner E, Weppler A. Coronary artery disease and revascularization associated with immune checkpoint blocker myocarditis: Report from an international registry. European Journal Of Cancer 2022, 177: 197-205. PMID: 36030143, PMCID: PMC10165738, DOI: 10.1016/j.ejca.2022.07.018.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseImmune checkpoint blockersCoronary revascularizationArtery diseaseCAD groupInternational registryPrompt clinical diagnosisAcute coronary syndromeCoronary artery stenosisAdjustment of ageCause deathCoronary syndromeIndex hospitalisationSteroid administrationCheckpoint blockersCoronary angiographyArtery stenosisCoronary angiogramPoor outcomeSevere presentationRevascularizationPatientsCardiac pathologyClinical diagnosisMyocarditisNext Generation Risk Markers in Preventive Cardio-oncology
Lamberg M, Rossman A, Bennett A, Painter S, Goodman R, MacLeod J, Maddula R, Rayan D, Doshi K, Bick A, Bailey S, Brown S. Next Generation Risk Markers in Preventive Cardio-oncology. Current Atherosclerosis Reports 2022, 24: 443-456. PMID: 35441347, PMCID: PMC10026729, DOI: 10.1007/s11883-022-01021-x.Peer-Reviewed Original ResearchConceptsClonal hematopoiesis of indeterminate potentialBreast arterial calcificationCoronary artery calcificationPurpose of reviewCardiovascular diseaseCoronary artery diseaseRisk stratificationRisk markersCVD risk assessmentCancer treatmentArtery calcificationImprove CV risk stratificationPresence of clonal hematopoiesis of indeterminate potentialAtherosclerotic CVDIndependent of traditional CV risk factorsLong-term CVD outcomesIncreased risk of CVDTraditional CV risk factorsCV risk markersPrediction of coronary artery diseaseCardio-oncology practiceLung cancer screeningCV risk factorsCVD risk calculatorsCV risk stratificationCoronary artery stenosis
2021
Use of Mechanical Circulatory Support Devices Among Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock
Dhruva SS, Ross JS, Mortazavi BJ, Hurley NC, Krumholz HM, Curtis JP, Berkowitz AP, Masoudi FA, Messenger JC, Parzynski CS, Ngufor CG, Girotra S, Amin AP, Shah ND, Desai NR. Use of Mechanical Circulatory Support Devices Among Patients With Acute Myocardial Infarction Complicated by Cardiogenic Shock. JAMA Network Open 2021, 4: e2037748. PMID: 33616664, PMCID: PMC7900859, DOI: 10.1001/jamanetworkopen.2020.37748.Peer-Reviewed Original ResearchMeSH KeywordsAgedAssisted CirculationCross-Sectional StudiesExtracorporeal Membrane OxygenationFemaleHeart ArrestHeart-Assist DevicesHospitals, High-VolumeHospitals, Low-VolumeHospitals, TeachingHumansIntra-Aortic Balloon PumpingMaleMiddle AgedMyocardial InfarctionPercutaneous Coronary InterventionRisk FactorsShock, CardiogenicConceptsMicroaxial left ventricular assist deviceIntra-aortic balloon pumpLeft ventricular assist devicePercutaneous coronary interventionAcute myocardial infarctionMechanical circulatory support devicesCardiogenic shockHospital-level variationSignificant hospital-level variationCirculatory support devicesMCS devicesUse of IABPDevice useMedian proportionAcute Myocardial Infarction ComplicatedCardiology-National Cardiovascular Data RegistryChest Pain-MI RegistryLimited clinical trial evidenceNational Cardiovascular Data RegistryMyocardial Infarction ComplicatedFirst medical contactSupport devicesClinical trial evidenceExtracorporeal membrane oxygenationCoronary artery stenosis
2018
Percutaneous Left Main Coronary Intervention: A Review of Plaque Modification in Left Main Percutaneous Coronary Intervention
Shah CA, Pfau SE. Percutaneous Left Main Coronary Intervention: A Review of Plaque Modification in Left Main Percutaneous Coronary Intervention. Journal Of Clinical Medicine 2018, 7: 180. PMID: 30041422, PMCID: PMC6068647, DOI: 10.3390/jcm7070180.Peer-Reviewed Original ResearchPercutaneous coronary interventionMain percutaneous coronary interventionCoronary interventionDrug eluting stentsPlaque volumeIntravascular ultrasoundLeft main percutaneous coronary interventionMain coronary artery stenosisLMCA bifurcation lesionsMain Coronary InterventionCoronary bypass surgeryCurrent treatment algorithmsCoronary artery stenosisIndividual patient characteristicsMinimal stent areaLMCA lesionsLMCA stenosisBypass surgeryPatient characteristicsPlaque modificationArtery stenosisDES eraTreatment algorithmCoronary segmentsBifurcation lesions
2013
Evaluation of the novel novolimus-eluting bioresorbable vascular scaffold for the treatment of de novo coronary artery stenosis: serial optical coherence tomography analysis of the DESolve NX study
Chamie D, Costa J, Costa R, Verheye S, Ormiston J, Maeng M, Vrolix M, Bhat V, Morrison L, Abizaid A. Evaluation of the novel novolimus-eluting bioresorbable vascular scaffold for the treatment of de novo coronary artery stenosis: serial optical coherence tomography analysis of the DESolve NX study. European Heart Journal 2013, 34: p3053. DOI: 10.1093/eurheartj/eht309.p3053.Peer-Reviewed Original ResearchOptical coherence tomographyPost-procedureNeointimal hyperplasiaFollow-upPlaque prolapseOptical coherence tomography analysisDegree of strut coverageFrequency of malapposed strutsDegree of neointimal hyperplasiaNeointimal hyperplasia thicknessIndependent core laboratoryImaging end pointsCoronary artery stenosisSix-month follow-upNative coronary lesionsScaffold appositionBioresorbable scaffoldsOCT examinationOCT evaluationOCT analysisOCT resultsPoly-L-lactideCoherence tomographyCore laboratoryArtery stenosis
2012
Race and gender variation in the QT interval and its association with mortality in patients with coronary artery disease: Results from the Duke Databank for Cardiovascular Disease (DDCD)
Williams ES, Thomas KL, Broderick S, Shaw LK, Velazquez EJ, Al-Khatib SM, Daubert JP. Race and gender variation in the QT interval and its association with mortality in patients with coronary artery disease: Results from the Duke Databank for Cardiovascular Disease (DDCD). American Heart Journal 2012, 164: 434-441. PMID: 22980312, DOI: 10.1016/j.ahj.2012.05.024.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseCause mortalityArtery diseaseProlonged QTcRisk factorsQT intervalMortality riskLow glomerular filtration rateHigher diastolic blood pressureNative coronary artery stenosisCardiac risk factorsLow ejection fractionDiastolic blood pressureGlomerular filtration rateCoronary artery stenosisRisk of deathCardiac catheterizationCardiac eventsDuke DatabankBlood pressureEjection fractionQTc intervalQTc prolongationArtery stenosisBaseline electrocardiogramCharacteristics and Long-Term Outcomes of Percutaneous Revascularization of Unprotected Left Main Coronary Artery Stenosis in the United States A Report From the National Cardiovascular Data Registry, 2004 to 2008
Brennan JM, Dai D, Patel MR, Rao SV, Armstrong EJ, Messenger JC, Curtis JP, Shunk KA, Anstrom KJ, Eisenstein EL, Weintraub WS, Peterson ED, Douglas PS, Hillegass WB. Characteristics and Long-Term Outcomes of Percutaneous Revascularization of Unprotected Left Main Coronary Artery Stenosis in the United States A Report From the National Cardiovascular Data Registry, 2004 to 2008. Journal Of The American College Of Cardiology 2012, 59: 648-654. PMID: 22322080, DOI: 10.1016/j.jacc.2011.10.883.Peer-Reviewed Original ResearchConceptsULMCA percutaneous coronary interventionPercutaneous coronary interventionMain coronary artery stenosisU.S. clinical practiceMajor adverse eventsCoronary artery stenosisAdverse eventsULMCA stenosisCoronary interventionHazard ratioArtery stenosisUnprotected left main coronary artery stenosisClinical practiceLeft main coronary artery stenosisComposite major adverse eventsUnited States A ReportPercutaneous coronary intervention registryHospital mortality rateCoronary Intervention RegistryLong-term outcomesHigh procedural riskBare metal stentsDrug-eluting stentsHospital mortalityPCI use
2011
CHARACTERISTICS AND OUTCOMES OF PERCUTANEOUS REVASCULARIZATION OF UNPROTECTED LEFT MAIN CORONARY ARTERY STENOSIS IN THE UNITED STATES: RESULTS FROM THE NATIONAL CARDIOVASCULAR DATA REGISTRY, 2004-2008
Brennan J, Douglas P, Dai D, Anstrom K, Armstrong E, Messenger J, Patel M, Rao S, Honeycutt E, Eisenstein E, Curtis J, Shunk K, Weintraub W, Peterson E, Hillegass W. CHARACTERISTICS AND OUTCOMES OF PERCUTANEOUS REVASCULARIZATION OF UNPROTECTED LEFT MAIN CORONARY ARTERY STENOSIS IN THE UNITED STATES: RESULTS FROM THE NATIONAL CARDIOVASCULAR DATA REGISTRY, 2004-2008. Journal Of The American College Of Cardiology 2011, 57: e899. DOI: 10.1016/s0735-1097(11)60899-1.Peer-Reviewed Original ResearchUtilization of frequency domain optical coherence tomography and fractional flow reserve to assess intermediate coronary artery stenoses: conciliating anatomic and physiologic information
Stefano G, Bezerra H, Attizzani G, Chamié D, Mehanna E, Yamamoto H, Costa M. Utilization of frequency domain optical coherence tomography and fractional flow reserve to assess intermediate coronary artery stenoses: conciliating anatomic and physiologic information. The International Journal Of Cardiovascular Imaging 2011, 27: 299. PMID: 21409535, PMCID: PMC3984934, DOI: 10.1007/s10554-011-9847-9.Peer-Reviewed Original ResearchConceptsFractional flow reserveIntermediate coronary artery stenosisFrequency domain optical coherence tomographyOptical coherence tomographyCoronary artery stenosisFD-OCTFlow reserveAnatomical assessmentCoherence tomographyArtery stenosisSeverity of coronary diseaseAcute coronary syndromeReference vessel diameterComplex clinical scenariosConsecutive interventional proceduresMinimal lumen areaAngiographically intermediate stenosesHigh-resolution imaging modalityPotential complementary roleInvasive assessmentCoronary syndromeCoronary diseaseClinical scenariosClinical useIntermediate stenosisA Prospective Natural-History Study of Coronary Atherosclerosis
Stone GW, Maehara A, Lansky AJ, de Bruyne B, Cristea E, Mintz GS, Mehran R, McPherson J, Farhat N, Marso SP, Parise H, Templin B, White R, Zhang Z, Serruys PW. A Prospective Natural-History Study of Coronary Atherosclerosis. New England Journal Of Medicine 2011, 364: 226-235. PMID: 21247313, DOI: 10.1056/nejmoa1002358.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAngioplasty, Balloon, CoronaryCoronary AngiographyCoronary Artery DiseaseCoronary VesselsDisease ProgressionFemaleHumansKaplan-Meier EstimateMaleMiddle AgedPatient ReadmissionProportional Hazards ModelsProspective StudiesRecurrenceRisk FactorsUltrasonography, InterventionalConceptsMajor adverse cardiovascular eventsAdverse cardiovascular eventsAcute coronary syndromeNonculprit lesionsPercutaneous coronary interventionThin-cap fibroatheromaCardiovascular eventsCoronary syndromeCulprit lesionCoronary interventionPlaque burdenIntravascular ultrasonographyLuminal areaSubsequent major adverse cardiovascular eventsLesion-related risk factorsMild coronary artery stenosisProspective natural history studyLarger plaque burdenCoronary artery stenosisMinimal luminal areaNatural history studiesRecurrent eventsSmall luminal areaMedian followCoronary atherosclerosis
2009
Usefulness of the Duke Sudden Cardiac Death Risk Score for Predicting Sudden Cardiac Death in Patients With Angiographic (>75% Narrowing) Coronary Artery Disease
Atwater BD, Thompson VP, Vest RN, Shaw LK, Mazzei WR, Al-Khatib SM, Hranitzky PM, Bahnson TD, Velazquez EJ, Califf RM, Lee KL, Roe MT. Usefulness of the Duke Sudden Cardiac Death Risk Score for Predicting Sudden Cardiac Death in Patients With Angiographic (>75% Narrowing) Coronary Artery Disease. The American Journal Of Cardiology 2009, 104: 1624-1630. PMID: 19962465, DOI: 10.1016/j.amjcard.2009.07.042.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseSCD risk scoreRisk of SCDArtery diseaseRisk scoreSCD riskDepressed left ventricular ejection fractionAngiographic coronary artery diseasePredicting Sudden Cardiac DeathLeft ventricular ejection fractionNative coronary artery stenosisCox proportional hazards modelVentricular ejection fractionSudden cardiac deathCoronary artery stenosisDeath risk scorePatient characteristic variablesRisk prediction toolsDiseased coronary arteriesProportional hazards modelAngiographic characteristicsRisk patientsCardiac deathCoronary angiographyDiabetes mellitus
2008
Effectiveness of Drug-Eluting Stent Implantation for Patients With Unprotected Left Main Coronary Artery Stenosis
Kim YH, Dangas GD, Solinas E, Aoki J, Parise H, Kimura M, Franklin-Bond T, Dasgupta NK, Kirtane AJ, Moussa I, Lansky AJ, Collins M, Stone GW, Leon MB, Moses JW, Mehran R. Effectiveness of Drug-Eluting Stent Implantation for Patients With Unprotected Left Main Coronary Artery Stenosis. The American Journal Of Cardiology 2008, 101: 801-806. PMID: 18328844, DOI: 10.1016/j.amjcard.2007.10.052.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBlood Vessel Prosthesis ImplantationCoated Materials, BiocompatibleCoronary AngiographyCoronary StenosisElectrocardiographyFemaleFollow-Up StudiesHumansImmunosuppressive AgentsMaleMyocardial RevascularizationPaclitaxelProspective StudiesSirolimusStentsTreatment OutcomeTubulin ModulatorsUltrasonography, InterventionalConceptsHigh surgical riskMain coronary artery stenosisMajor adverse cardiac eventsUnprotected LMCA stenosisAdverse cardiac eventsCoronary artery stenosisSurgical riskLMCA stenosisCardiac eventsArtery stenosisStent thrombosisMyocardial infarctionBifurcation stenosisUnprotected left main coronary artery stenosisLeft main coronary artery stenosisDrug-eluting stent placementUrgent percutaneous coronary interventionQ-wave myocardial infarctionFeasible therapeutic alternativeOutcomes of patientsPercutaneous coronary interventionPaclitaxel-eluting stentsSingle-stent strategyUnfavorable clinical outcomeSirolimus-eluting stents
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