2025
Personalizing core decompression grafting technique for osteonecrosis of the femoral head: calculating the volume of bone resected and adjunct volume required to fill the defect
Bergemann R, Massey A, Tommasini S, Wiznia D. Personalizing core decompression grafting technique for osteonecrosis of the femoral head: calculating the volume of bone resected and adjunct volume required to fill the defect. Journal Of Orthopaedic Surgery And Research 2025, 20: 229. PMID: 40033401, PMCID: PMC11874654, DOI: 10.1186/s13018-025-05606-5.Peer-Reviewed Original ResearchConceptsAdjunctive therapyVolume of boneCore decompressionBone marrow aspirate concentrateRisk of complicationsFemoral headSynthetic bone substituteAmount of boneBone substituteAspirate concentrateExpandable reamerBone regenerationBone graftPrevent collapseDebilitating diseaseReamer systemBoneAdjunctGrafting techniqueDecompression
2024
Impact of Surgeon Volume on Perioperative Complications and Survival to Total Hip Arthroplasty Following Femoral Head Core Decompression
Sanchez J, Jiang W, Dhodapkar M, Radford Z, Seddio A, Li M, Wiznia D, Grauer J. Impact of Surgeon Volume on Perioperative Complications and Survival to Total Hip Arthroplasty Following Femoral Head Core Decompression. JAAOS Global Research And Reviews 2024, 8: e24.00153. PMCID: PMC11578193, DOI: 10.5435/jaaosglobal-d-24-00153.Peer-Reviewed Original ResearchFemoral head osteonecrosisHip fractureInvasive proceduresCore decompressionHigh-volume surgeon groupImpact of surgeon volumeTotal hip arthroplastyKaplan-Meier survival analysisHigh-volume surgeonsMinimally invasive procedureSurgeon volume categoriesStatistically significant differenceAssess complicationsPerioperative complicationsPostoperative complicationsElixhauser Comorbidity IndexAdult patientsVolume surgeonsTreatment optionsAdverse eventsSurgeon volumeSurgeon groupComorbidity indexMultivariate analysisComplicationsFabricating patient-specific 3D printed drill guides to treat femoral head avascular necrosis
Bell C, Feizi A, Roytman G, Ramji A, Tommasini S, Wiznia D. Fabricating patient-specific 3D printed drill guides to treat femoral head avascular necrosis. 3D Printing In Medicine 2024, 10: 10. PMID: 38564090, PMCID: PMC10986134, DOI: 10.1186/s41205-024-00208-z.Peer-Reviewed Original ResearchUsing Computed Tomography-Based Three-dimensional Modeling and Computer Navigation for Minimally Invasive Core Decompression and Adjuvant Orthobiologic Therapy of Femoral Head Avascular Necrosis
Feizi A, Bell C, Roytman G, Park N, Wang A, Tommasini S, Wiznia D. Using Computed Tomography-Based Three-dimensional Modeling and Computer Navigation for Minimally Invasive Core Decompression and Adjuvant Orthobiologic Therapy of Femoral Head Avascular Necrosis. Arthroplasty Today 2024, 26: 101337. PMID: 38497084, PMCID: PMC10940782, DOI: 10.1016/j.artd.2024.101337.Peer-Reviewed Original ResearchFemoral head avascular necrosisAvascular necrosisSurgical techniqueCore decompressionBone marrow aspirate concentrateDelay disease progressionOutcome of core decompressionAdjuvant therapyCellular therapyAspirate concentrateDisease progressionFemoral head collapseImprove outcomesLesionsDebilitating conditionTherapyComputer navigationNecrosisDecompressionHead collapseThree-dimensional modelFemoral headFemoral Head Core Decompressions: Characterization of Subsequent Conversion to Total Hip Arthroplasty and Related Complications
Jiang W, Sanchez J, Dhodapkar M, Li M, Wiznia D, Grauer J. Femoral Head Core Decompressions: Characterization of Subsequent Conversion to Total Hip Arthroplasty and Related Complications. JAAOS Global Research And Reviews 2024, 8: e24.00024. PMID: 38437034, PMCID: PMC10906578, DOI: 10.5435/jaaosglobal-d-24-00024.Peer-Reviewed Original Research
2016
Treatment of Pre-Collapse Stages of Osteonecrosis of the Femoral Head: A Systematic Review of Randomized Control Trials
Villa J, Husain S, van der List J, Gianakos A, Lane J. Treatment of Pre-Collapse Stages of Osteonecrosis of the Femoral Head: A Systematic Review of Randomized Control Trials. HSS Journal ® 2016, 12: 261-271. PMID: 27703421, PMCID: PMC5026659, DOI: 10.1007/s11420-016-9505-9.Peer-Reviewed Original ResearchRandomized clinical trialsFemoral head collapseBone marrow mesenchymal cellsCore decompressionPre-collapse ONFHHead collapseLower riskFemoral headSystematic reviewLow-level evidence studiesMore RCTsQuestions/PurposesThe purposeNew combination therapiesMeta-Analyses (PRISMA) guidelinesRandomized control trialStandardized outcome measuresPreferred Reporting ItemsPre-collapse stageMethodsUsing PubMedRadiologic outcomesBisphosphonate treatmentClinical evidenceMarrow mesenchymal cellsCombination therapyFunctional outcomeThe Efficacy of Bisphosphonates with Core Decompression and Mesenchymal Stem Cells Compared with Bisphosphonates Alone in the Treatment of Osteonecrosis of the Hip: A Retrospective Study
Gianakos A, Moya-Angeler J, Duggal S, Zambrana L, Fields K, Mintz D, Cornell C, Lane J. The Efficacy of Bisphosphonates with Core Decompression and Mesenchymal Stem Cells Compared with Bisphosphonates Alone in the Treatment of Osteonecrosis of the Hip: A Retrospective Study. HSS Journal ® 2016, 12: 137-144. PMID: 27385942, PMCID: PMC4916091, DOI: 10.1007/s11420-016-9487-7.Peer-Reviewed Original ResearchModified Harris Hip ScoreVisual analogue scoreTotal hip arthroplastyBisphosphonate therapyCore decompressionMesenchymal stem cellsFunctional outcomeTreatment groupsHip replacementFemoral headEfficacy of bisphosphonatesFicat stage IRadiologic outcome measuresHarris hip scoreYear of diagnosisTreatment of osteonecrosisFuture prospective studiesEarly-stage ONFHInclusion/exclusion criteriaStem cellsJoint preserving proceduresTotal hip replacementProgression of collapseFicat stageInstitution's registry
2015
Current concepts on osteonecrosis of the femoral head
Moya-Angeler J, Gianakos A, Villa J, Ni A, Lane J. Current concepts on osteonecrosis of the femoral head. World Journal Of Orthopedics 2015, 6: 590-601. PMID: 26396935, PMCID: PMC4573503, DOI: 10.5312/wjo.v6.i8.590.Peer-Reviewed Original ResearchMagnetic resonance imagingFemoral headCore decompressionFrog-leg lateral radiographsNatural historyFirst radiographic changeTrue natural historyLevel 1 evidenceOptimal treatment protocolTotal hip arthroplastyJoint preserving proceduresPre-collapse stageOsteonecrosis diagnosisPlain anteroposteriorSurgical treatmentAvascular necrosisPlain radiographsSclerotic changesTreatment optionsMinimal symptomsRadiographic changesTreatment modalitiesRisk factorsPharmacologic agentsSymptomatic stage
2013
Osteonecrosis of the Knee — Which Joint Preservation Procedures Work?
Lieberman JR, Varthi AG, Polkowski GG. Osteonecrosis of the Knee — Which Joint Preservation Procedures Work? The Journal Of Arthroplasty 2013, 29: 52-56. PMID: 23725928, DOI: 10.1016/j.arth.2013.04.036.Peer-Reviewed Original ResearchConceptsMulti-center randomized trialsAdditional surgical treatmentJoint preservation proceduresCore decompressionSurgical treatmentAdditional surgeryRandomized trialsInclusion criteriaSystematic reviewKnee jointOsteochondral graftsKneePreservation proceduresOsteonecrosisFailure rateBest procedurePatientsSurgeryGraftDiseaseTrialsDecompression
2007
Current Practices of AAHKS Members in the Treatment of Adult Osteonecrosis of the Femoral Head
McGrory BJ, York SC, Iorio R, Macaulay W, Pelker RR, Parsley BS, Teeny SM. Current Practices of AAHKS Members in the Treatment of Adult Osteonecrosis of the Femoral Head. Journal Of Bone And Joint Surgery 2007, 89: 1194-1204. DOI: 10.2106/00004623-200706000-00006.Peer-Reviewed Original ResearchConceptsFemoral headHigh-volume arthroplasty surgeonsSteinberg classification systemCollaborative multicenter studyCare of adultsHypothetical clinical scenariosAspects of careCurrent treatment practicesTotal hip replacementGroup of surgeonsAmerican orthopaedic surgeonsAdult osteonecrosisPostcollapse osteonecrosisPrecollapse osteonecrosisCore decompressionNonoperative managementAdult patientsMulticenter studyProspective studyKnee surgeryTreatment preferencesOsteonecrosisArthroplasty surgeonsKnee surgeonsClinical scenariosCurrent Practices of AAHKS Members in the Treatment of Adult Osteonecrosis of the Femoral Head
McGrory B, York S, Iorio R, Macaulay W, Pelker R, Parsley B, Teeny S. Current Practices of AAHKS Members in the Treatment of Adult Osteonecrosis of the Femoral Head. Journal Of Bone And Joint Surgery 2007, 89: 1194-1204. PMID: 17545421, DOI: 10.2106/jbjs.f.00302.Peer-Reviewed Original ResearchConceptsFemoral headHigh-volume arthroplasty surgeonsSteinberg classification systemCollaborative multicenter studyCare of adultsHypothetical clinical scenariosAspects of careCurrent treatment practicesTotal hip replacementGroup of surgeonsAmerican orthopaedic surgeonsAdult osteonecrosisPostcollapse osteonecrosisPrecollapse osteonecrosisCore decompressionNonoperative managementAdult patientsMulticenter studyProspective studyKnee surgeryTreatment preferencesOsteonecrosisArthroplasty surgeonsKnee surgeonsClinical scenarios
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