2024
Endovascular arterial embolization versus conservative management with nasal packing alone for severe epistaxis: a nationwide cohort study
Chen H, Khunte M, Colasurdo M, Gunawardane S, Malhotra A, Gandhi D. Endovascular arterial embolization versus conservative management with nasal packing alone for severe epistaxis: a nationwide cohort study. Journal Of NeuroInterventional Surgery 2024, jnis-2024-022790. PMID: 39715667, DOI: 10.1136/jnis-2024-022790.Peer-Reviewed Original ResearchEndovascular arterial embolizationNasal packingSevere epistaxisPropensity score matchingNationwide Readmissions DatabaseArtery embolizationIschemic strokeCohort studyRates of patient morbidityHemorrhage risk factorsConservative management groupConservative managementRetrospective cohort studyNationwide cohort studyRate of ischemic strokeBalance patient characteristicsContemporary real-world dataAssociated with lower ratesPatients admitted to hospitalNon-routine dischargeRisk of ischemic strokeRecurrent epistaxisRecurrence ratePatient morbidityPatient characteristics8714 Impact of Adrenalectomy Versus Conservative Therapy On Frailty In Mild Autonomous Cortisol Secretion: A Prospective Multi-Center Cohort Study
Bassiony M, Dogra P, Šambula L, Saini J, Ambroziak U, Kastelan D, Bancos I. 8714 Impact of Adrenalectomy Versus Conservative Therapy On Frailty In Mild Autonomous Cortisol Secretion: A Prospective Multi-Center Cohort Study. Journal Of The Endocrine Society 2024, 8: bvae163.213. PMCID: PMC11454724, DOI: 10.1210/jendso/bvae163.213.Peer-Reviewed Original ResearchNonfunctioning adrenal adenomasAutonomous cortisol secretionPost-dexamethasone cortisolTreated patientsFrailty indexCortisol secretionMulti-center cohort studyCompared to patientsImpact of adrenalectomyFrailty prevalenceAdrenal adenomaPost-adrenalectomyConservative therapyMedian ageCohort studyAdrenalectomyPatientsConservative managementFrailty assessmentAdverse health outcomesPrevalenceBaselineBaseline FIHealth outcomesImproved FI
2023
Delivery outcomes in the subsequent pregnancy following the conservative management of placenta accreta spectrum disorder: a systematic review and meta-analysis
JAVINANI A, QADERI S, HESSAMI K, SHAINKER S, SHAMSHIRSAZ A, Fox K, MUSTAFA H, SUBRAMANIAM A, KHANDELWAL M, SANDLIN A, DUZYJ C, LYELL D, ZUCKERWISE L, NEWTON J, KINGDOM J, HARRISON R, SHRIVASTAVA V, GREINER A, Loftin R, GENC M, ATASI L, ABDEL-RAZEQ S, BENNETT K, CARUSI D, EINERSON B, GILNER J, CARVER A, SILVER R, SHAMSHIRSAZ A. Delivery outcomes in the subsequent pregnancy following the conservative management of placenta accreta spectrum disorder: a systematic review and meta-analysis. American Journal Of Obstetrics And Gynecology 2023, 230: 485-492.e7. PMID: 37918506, DOI: 10.1016/j.ajog.2023.10.047.Peer-Reviewed Original ResearchPlacenta accreta spectrum disordersAdverse maternal outcomesSubsequent pregnancy outcomeConservative managementPregnancy outcomesSubsequent pregnancyMaternal outcomesCesarean hysterectomySystematic reviewComposite adverse maternal outcomeFavorable pregnancy outcomeUterine-sparing techniquesInverse variance methodSpectrum disorderRandom-effects modelMaternal morbiditySurgical complicationsPostpartum hemorrhageAdverse outcomesResection surgerySuch high incidenceDelivery outcomesHigh incidencePregnancyProvider preparationSpontaneous vesicoureteral reflux resolution curves based on ureteral diameter ratio
Arlen A, Leong T, Kirsch A, Cooper C. Spontaneous vesicoureteral reflux resolution curves based on ureteral diameter ratio. Journal Of Pediatric Urology 2023, 19: 468.e1-468.e6. PMID: 37188603, DOI: 10.1016/j.jpurol.2023.04.028.Peer-Reviewed Original ResearchConceptsUreteral diameter ratioUrinary tract infectionPrimary vesicoureteral refluxVesicoureteral refluxSpontaneous resolutionRisk groupsBreakthrough febrile urinary tract infectionDistal ureteral diameter ratioFebrile urinary tract infectionLargest ureteral diameterObjective prognostic informationGrade of refluxHigh-risk patientsLow-risk patientsHigh-risk groupLow-risk groupLow-risk childrenVUR resolutionPrimary refluxProphylactic antibioticsVUR gradeConservative managementPersistent refluxRisk patientsTract infectionsFull calcium jacket: Conservative management of a traumatic aortic injury
Tripathi R, Ellauzi H, Zafar M, Ziganshin B, Elefteriades J. Full calcium jacket: Conservative management of a traumatic aortic injury. Journal Of Vascular Surgery Cases And Innovative Techniques 2023, 9: 101132. PMID: 37139352, PMCID: PMC10149390, DOI: 10.1016/j.jvscit.2023.101132.Peer-Reviewed Original ResearchAdvances in Cartilage Repair
Azam M, Butler J, Duenes M, McAllister T, Walls R, Gianakos A, Kennedy J. Advances in Cartilage Repair. Orthopedic Clinics Of North America 2023, 54: 227-236. PMID: 36894294, DOI: 10.1016/j.ocl.2022.11.007.Peer-Reviewed Original ResearchConceptsAutologous osteochondral transplantationBone marrow stimulationPoor healing capacityAnkle painUncontained lesionsConservative managementArthroscopic debridementCystic lesionsBiological adjuvantsTraumatic etiologyOsteochondral transplantationInvasive proceduresOsteochondral lesionsLarge lesionsMarrow stimulationAnkle jointLesionsSmall lesionsScaffold-based therapiesHealing capacityPatientsArticular cartilageUnsatisfactory resultsCartilage repairDebridementChapter 23 Vaginal remnants, strictures, and fistula after masculinizing surgery
Sterling J, Schardein J, Nikolavsky D. Chapter 23 Vaginal remnants, strictures, and fistula after masculinizing surgery. 2023, 381-398. DOI: 10.1016/b978-0-323-98377-8.00023-3.Peer-Reviewed Original ResearchGender affirmation surgeryGenital reconstructive surgeryIndividual patient goalsVaginal remnantCommon complicationComplication rateConservative managementPreoperative workupSurgical revisionUrethrocutaneous fistulaTreatment optionsUrethral strictureEndoscopic repairPatient goalsTransmasculine patientsSurgical techniqueReconstructive surgerySurgical reconstructionSurgeryClinical decisionComplicationsPatientsVaginal cavityGenital surgeryFistula
2022
Characteristics and Patient-Reported Outcomes of Advanced CKD Patients Treated With Conservative Management vs. Dialysis: Findings From the Prospective NIH OPTIMAL Cohort
Rhee C, Yoon J, Otobe Y, Crowley S, Kovesdy C, Mukamel D, Narasaki Y, Novoa-Vargas A, Rivera S, You A, Nguyen D, Kalantar-Zadeh K. Characteristics and Patient-Reported Outcomes of Advanced CKD Patients Treated With Conservative Management vs. Dialysis: Findings From the Prospective NIH OPTIMAL Cohort. Journal Of The American Society Of Nephrology 2022, 33: 297-297. DOI: 10.1681/asn.20223311s1297a.Peer-Reviewed Original ResearchImpact of Race/Ethnicity and Age on Hospitalization Outcomes in Advanced CKD Patients Treated With Conservative Management vs. Dialysis
Rhee C, You A, Narasaki Y, Mukamel D, Crowley S, Yoon J, Kovesdy C, Nguyen D, Kalantar-Zadeh K. Impact of Race/Ethnicity and Age on Hospitalization Outcomes in Advanced CKD Patients Treated With Conservative Management vs. Dialysis. Journal Of The American Society Of Nephrology 2022, 33: 42-42. DOI: 10.1681/asn.20223311s142d.Peer-Reviewed Original ResearchHospitalization Lengths of Stay Among a National Cohort of Advanced CKD Patients Treated With Conservative Management vs. Dialysis
You A, Kalantar-Zadeh K, Narasaki Y, Mukamel D, Crowley S, Yoon J, Kovesdy C, Nguyen D, Rhee C. Hospitalization Lengths of Stay Among a National Cohort of Advanced CKD Patients Treated With Conservative Management vs. Dialysis. Journal Of The American Society Of Nephrology 2022, 33: 581-581. DOI: 10.1681/asn.20223311s1581a.Peer-Reviewed Original ResearchNatural history of bicuspid aortic valves and ascending aortic aneurysms: Aortic center experience
Bellaire CP, Tharakan SM, Roy J, Puskas JD, Di Luozzo G. Natural history of bicuspid aortic valves and ascending aortic aneurysms: Aortic center experience. Journal Of Cardiac Surgery 2022, 37: 2326-2335. PMID: 35535018, DOI: 10.1111/jocs.16597.Peer-Reviewed Original ResearchConceptsBicuspid aortic valveAdverse event ratesTAV patientsEntire cohortAortic aneurysmAortic valveComputerized tomographyLow adverse event ratesOverall adverse event rateNatural historyEvent ratesTricuspid aortic valve patientsValve typeRoutine computerized tomographyMore CT scansAortic valve patientsCoronary artery diseaseMean aneurysm sizeAneurysm growth rateAortic valve typeSimilar natural historyAortic eventsConservative managementSmoking historyUnmatched cohortMO345: Clinical Characteristics and Trajectory in a National Cohort of Veterans Treated With Conservative Management Versus Dialysis
Narasaki Y, Rhee C, You A, Mukamel D, Novoa A, Otobe Y, Daza A, Kovesdy C, Crowley S, Nguyen D, Kalantar-Zadeh K. MO345: Clinical Characteristics and Trajectory in a National Cohort of Veterans Treated With Conservative Management Versus Dialysis. Nephrology Dialysis Transplantation 2022, 37: gfac068.055. DOI: 10.1093/ndt/gfac068.055.Peer-Reviewed Original ResearchChronic kidney diseaseAdvanced chronic kidney diseaseEnd-stage renal diseaseConservative managementUS veteransClinical characteristicsIndex eGFRNational cohortNon-dialysis dependent chronic kidney diseaseDependent chronic kidney diseaseUnited States Renal Data SystemAdvanced CKD patientsDominant treatment paradigmNon-dialytic managementReceipt of dialysisForm of dialysisRenal replacement therapySimilar sex distributionVeterans Health AdministrationHealthcare systemVA healthcare systemYounger age distributionCKD cohortCKD outcomesCKD patientsMO486: Comparison of Hospitalization Lengths of Stay Among a National Cohort of Advanced CKD Patients Treated With Conservative Management Vs. Dialysis
You A, Kalantar-Zadeh K, Narasaki Y, Mukamel D, Crowley S, Novoa A, Otobe Y, Kovesdy C, Nguyen D, Rhee C. MO486: Comparison of Hospitalization Lengths of Stay Among a National Cohort of Advanced CKD Patients Treated With Conservative Management Vs. Dialysis. Nephrology Dialysis Transplantation 2022, 37: gfac071.017. DOI: 10.1093/ndt/gfac071.017.Peer-Reviewed Original ResearchAdvanced CKD patientsTime of hospitalizationLongest average LOSCKD patientsConservative managementIndex eGFRAverage LOSPrimary analysisSecondary analysisEarly dialysisDialysis patientsHospitalization lengthNational cohortPatient-centered treatment strategiesReceipt of dialysisGreater healthcare utilizationElectronic health record dataTiming of dialysisImpact of dialysisMedicare Advantage enrolleesHealth record dataLoss of independenceCKD cohortCKD outcomesDialysis transitionPostdural Puncture Headache—Risks and Current Treatment
Li H, Wang Y, Oprea AD, Li J. Postdural Puncture Headache—Risks and Current Treatment. Current Pain And Headache Reports 2022, 26: 441-452. PMID: 35353358, DOI: 10.1007/s11916-022-01041-x.Peer-Reviewed Original ResearchConceptsPostdural puncture headacheCurrent treatmentDevelopment of PDPHMild postdural puncture headacheSevere postdural puncture headacheSelf-limited headacheEpidural blood patchFirst-line treatmentLong-term complicationsTherapy of choiceDull achingHeadache riskPDPH patientsPharmacological managementConservative treatmentBlood patchConservative managementFrequent complicationNerve blockNeuraxial blockNeuraxial techniquesPuncture headacheBed restChronic headacheFemale sexOptimizing Small, Low-Risk, Unruptured Intracranial Aneurysm Treatment Using Game Theory
Boltyenkov A, Wang J, Malhotra A, Katz J, Dehdashti A, White T, Martinez G, Pandya A, Sanelli P. Optimizing Small, Low-Risk, Unruptured Intracranial Aneurysm Treatment Using Game Theory. American Journal Of Neuroradiology 2022, 43: 176-180. PMID: 35027349, PMCID: PMC8985687, DOI: 10.3174/ajnr.a7392.Peer-Reviewed Original Research
2021
Impact of Race/Ethnicity and Age on Survival in Advanced CKD Patients Treated with Conservative Management vs. Dialysis
You A, Kalantar-Zadeh K, Narasaki Y, Kovesdy C, Mukamel D, Crowley S, Novoa-Vargas A, Nguyen D, Rhee C. Impact of Race/Ethnicity and Age on Survival in Advanced CKD Patients Treated with Conservative Management vs. Dialysis. Journal Of The American Society Of Nephrology 2021, 32: 712-712. DOI: 10.1681/asn.20213210s1712b.Peer-Reviewed Original ResearchMalignant hyperthermia in severe COVID-19: 2 case reports
Ehteshami-Afshar S, Nikooie R, Reddy P, Chichra A, Siegel M. Malignant hyperthermia in severe COVID-19: 2 case reports. Emergency And Critical Care Medicine 2021, 1: 45-48. PMID: 38630110, PMCID: PMC8447731, DOI: 10.1097/ec9.0000000000000013.Peer-Reviewed Original ResearchPatients Obtain Meaningful Clinical Benefit After Hip Arthroscopy Despite Preoperative Psychological Distress: A Propensity-Matched Analysis of Mid-Term Outcomes
Saks BR, Glein RM, Jimenez AE, Ankem HK, Sabetian PW, Maldonado DR, Lall AC, Domb BG. Patients Obtain Meaningful Clinical Benefit After Hip Arthroscopy Despite Preoperative Psychological Distress: A Propensity-Matched Analysis of Mid-Term Outcomes. Arthroscopy The Journal Of Arthroscopic And Related Surgery 2021, 38: 773-782. PMID: 34019982, DOI: 10.1016/j.arthro.2021.05.010.Peer-Reviewed Original ResearchConceptsPatient-reported outcomesArthroscopic hip surgeryMid-term outcomesMeaningful clinical benefitPreoperative psychological distressHip surgeryBaseline psychological distressPsychological distressClinical benefitForm Health Survey mental component summary scoresPostoperative patient-reported outcomesPatient acceptable symptomatic stateVisual analog scale scoreMental component summary scoresSF-12 MCS scoresNon-distressed patientsAnalog scale scoreHarris hip scoreLower functional statusComponent summary scoresTime of presentationBody mass indexRetrospective comparative studyPain improvementConservative managementResection of Symptomatic Pineal Cysts Provides Durable Clinical Improvement: A Breakdown of Presenting Symptoms and Lessons Learned
Yeung JT, Young IM, Profyris C, Katsos K, Sughrue ME, Teo C. Resection of Symptomatic Pineal Cysts Provides Durable Clinical Improvement: A Breakdown of Presenting Symptoms and Lessons Learned. World Neurosurgery 2021, 150: e668-e674. PMID: 33771749, DOI: 10.1016/j.wneu.2021.03.087.Peer-Reviewed Original ResearchConceptsSymptomatic pineal cystsPineal cystsSurgical resectionClinical improvementDurable clinical improvementExhaustive conservative managementNon-headache symptomsDurable symptomatic reliefYears of agePresenting symptomConservative managementSymptomatic patientsSurgical candidacySymptomatic reliefVisual disturbancesClinical outcomesPatient populationRadiographic changesCerebral aqueductRetrospective analysisResectionPatientsVariable symptomsCystsHeadacheSurgical Management of Sialorrhea: A Systematic Review and Meta‐analysis
Schild S, Timashpolsky A, Ballard D, Horne S, Rosenfeld R, Plum A. Surgical Management of Sialorrhea: A Systematic Review and Meta‐analysis. Otolaryngology 2021, 165: 507-518. PMID: 33494642, DOI: 10.1177/0194599820985165.Peer-Reviewed Original ResearchConceptsSubmandibular gland excisionSystematic reviewSufficient symptom controlMajority of patientsStudy of patientsParotid duct ligationRandom-effects modelConsistent positive outcomesWeb of ScienceDry mouthSymptom controlConservative managementPostintervention outcomesSurgical managementSurgical interventionDental cariesStudy eligibilitySurgical approachGland excisionDuct ligationInclusion criteriaPatientsConcurrent proceduresIndependent investigatorsMeta-Analysis
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