2025
How to Use Imaging: Complex Cases of Atherosclerosis, Myocardial Inflammation, and Cardiomyopathy in Cardio-Oncology
Khattab M, Baig M, Zarif T, Barac A, Ferencik M, Henry M, Lopez-Mattei J, Redheuil A, Salem J, Scherrer-Crosbie M, Yang E, Baldassarre L. How to Use Imaging: Complex Cases of Atherosclerosis, Myocardial Inflammation, and Cardiomyopathy in Cardio-Oncology. Circulation Cardiovascular Imaging 2025, 18: e015981. PMID: 39772610, DOI: 10.1161/circimaging.124.015981.Peer-Reviewed Original ResearchConceptsCardio-oncologyCases of atherosclerosisCardiac magnetic resonance imagingCoronary computed tomography angiographySingle-photon emission computed tomographyImmune checkpoint inhibitorsLeft ventricular dysfunctionMultimodality cardiac imagingTyrosine kinase inhibitorsCardiac imaging modalitiesComputed tomography angiographyRisk of cardiovascular diseaseEmission computed tomographyPositron emission tomographyMagnetic resonance imagingCheckpoint inhibitorsVentricular dysfunctionMyocardial inflammationCoronary vasospasmAccelerated atherosclerosisKinase inhibitorsPatient populationDiagnosing such pathologiesCancer therapyCardiac imaging
2024
Renovascular hypertension – a primer for the radiologist
Dixe de Oliveira Santo I, Sindoni J, Czeyda-Pommersheim F, Solomon N, Sailer A, Bhatt S, Fananapazir G, Pellerito J, Revzin M. Renovascular hypertension – a primer for the radiologist. Abdominal Radiology 2024, 1-13. PMID: 39542950, DOI: 10.1007/s00261-024-04677-y.Peer-Reviewed Original ResearchRenovascular hypertensionRenal arteryCause of renovascular hypertensionComputed tomography angiographyMagnetic resonance angiographyDiagnosing RVHExtrinsic compressionSecondary hypertensionRare conditionImaging findingsPolyarteritis nodosaSurgical interventionFibromuscular dysplasiaAnatomical variantsPage kidneyPictorial reviewHypertension casesAccurate diagnosisMedical managementDiagnostic criteriaTreatment approachesImaging modalitiesHypertensionImpact diagnosisYoung femalesDeep learning for prediction of post-thrombectomy outcomes based on admission CT angiography in large vessel occlusion stroke
Sommer J, Dierksen F, Zeevi T, Tran A, Avery E, Mak A, Malhotra A, Matouk C, Falcone G, Torres-Lopez V, Aneja S, Duncan J, Sansing L, Sheth K, Payabvash S. Deep learning for prediction of post-thrombectomy outcomes based on admission CT angiography in large vessel occlusion stroke. Frontiers In Artificial Intelligence 2024, 7: 1369702. PMID: 39149161, PMCID: PMC11324606, DOI: 10.3389/frai.2024.1369702.Peer-Reviewed Original ResearchEnd-to-endComputed tomography angiographyLarge vessel occlusionConvolutional neural networkDeep learning pipelineTrain separate modelsLogistic regression modelsResNet-50Deep learningAdmission computed tomography angiographyNeural networkLearning pipelineAdmission CT angiographyPreprocessing stepDiagnosis of large vessel occlusionsLarge vessel occlusion strokeReceiver operating characteristic areaEnsemble modelAutomated modelPre-existing morbidityCT angiographyReperfusion successNeurological examCross-validationOcclusion strokeNon-invasive Estimation Of Right Ventricle-Pulmonary Artery Coupling Using Multiphase Cardiac Computed Tomography Angiography In Pig Model Of Acute Respiratory Distress Syndrome
Jang S, Thorn S, Vermillion B, Alashi A, Zohora F, Lee S, Ahn S, Burns R, Dela Cruz C, Zeiss C, Spinale F, Heerdt P, Sinusas A. Non-invasive Estimation Of Right Ventricle-Pulmonary Artery Coupling Using Multiphase Cardiac Computed Tomography Angiography In Pig Model Of Acute Respiratory Distress Syndrome. Journal Of Cardiovascular Computed Tomography 2024, 18: s46. DOI: 10.1016/j.jcct.2024.05.106.Peer-Reviewed Original ResearchArtificial Intelligence-based Morpho-volumetric Analysis of Pre- and Post-EVAR Infrarenal Abdominal Aortic Aneurysms Characterized on Computed Tomography Angiography
Weiss D, Hager T, Aboian M, Lin M, Renninghoff D, Holler W, Fischer U, Deuschl C, Aneja S, Aboian E. Artificial Intelligence-based Morpho-volumetric Analysis of Pre- and Post-EVAR Infrarenal Abdominal Aortic Aneurysms Characterized on Computed Tomography Angiography. Journal Of Vascular Surgery 2024, 79: e133-e134. DOI: 10.1016/j.jvs.2024.03.165.Peer-Reviewed Original ResearchInfrarenal abdominal aortic aneurysmComputed tomography angiographyAbdominal aortic aneurysmAortic aneurysm
2023
Operative Strategies for Aplastic Circle of Willis Arteries on CTA in Meningioma Surgery: A Case Report
Tabor J, Pappajohn A, Lei H, O'Brien J, Fulbright R, Morales-Valero S, Moliterno J. Operative Strategies for Aplastic Circle of Willis Arteries on CTA in Meningioma Surgery: A Case Report. Neurosurgery Open 2023, 4: e00058. PMID: 39959393, PMCID: PMC11809949, DOI: 10.1227/neuprac.0000000000000058.Peer-Reviewed Original ResearchComputed tomography angiographyInternal carotid arteryA1 arteriesPreoperative computed tomography angiographyCarotid arteryNeurovascular structuresRemnants of tumorsNear-total resectionSupraclinoid internal carotid arteryRelationship of tumorSphenoid wing meningiomaAnterior cerebral arteryAssociated with tumorsCircle of Willis arteriesCircle of WillisTumor involvementPreoperative imagingSurgical strategyMeningioma surgeryInvasive modalitiesCase reportMicrovascular DopplerCerebral arteryTumorPreoperative planningPredictors of Cerebral Embolic Debris During Transcatheter Aortic Valve Replacement: The SafePass 2 First-in-Human Study
Grubman D, Ahmad Y, Leipsic J, Blanke P, Pasupati S, Webster M, Nazif T, Parise H, Lansky A. Predictors of Cerebral Embolic Debris During Transcatheter Aortic Valve Replacement: The SafePass 2 First-in-Human Study. The American Journal Of Cardiology 2023, 207: 28-34. PMID: 37722198, DOI: 10.1016/j.amjcard.2023.08.137.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementAortic valve replacementValve replacementAtrial fibrillationHuman studiesEmbolic protection device useHigh embolic riskPrimary end pointHigh-risk patientsIndependent core laboratorySelf-expanding valvesComputed tomography angiographyProtection device useCerebral embolizationCerebrovascular eventsEmbolic riskAcute thrombusEmbolic burdenAngiography featuresTechnical successTomography angiographyEmbolic debrisValve useCore laboratoryEnd pointAdvances in Coronary Computed Tomographic Angiographic Imaging of Atherosclerosis for Risk Stratification and Preventive Care
Bienstock S, Lin F, Blankstein R, Leipsic J, Cardoso R, Ahmadi A, Gelijns A, Patel K, Baldassarre L, Hadley M, LaRocca G, Sanz J, Narula J, Chandrashekhar Y, Shaw L, Fuster V. Advances in Coronary Computed Tomographic Angiographic Imaging of Atherosclerosis for Risk Stratification and Preventive Care. JACC Cardiovascular Imaging 2023, 16: 1099-1115. PMID: 37178070, DOI: 10.1016/j.jcmg.2023.02.002.Peer-Reviewed Original ResearchConceptsCoronary Computed Tomography AngiographyCoronary artery diseaseAtherosclerotic plaquesArtery diseaseRisk stratificationPreventive carePlaque volumeHigh-risk plaque featuresNonobstructive coronary artery diseaseCoronary CTAMeasurements of atherosclerosisEffective risk stratificationHigh-risk patientsTotal plaque volumeComputed tomography angiographyPatient-specific factorsCoronary artery dimensionsIntravascular ultrasound measurementsHealth care systemCoronary dominanceCardiovascular preventionPatient subsetsPlaque featuresArtery sizeTomography angiographyTranscatheter Aortic Valve Replacement in Large Annuli Valves With the Supra-Annular, Self-Expandable Evolut Platform in a Real-World Registry
Dallan L, Tang G, Forrest J, Reardon M, Szeto W, Kodali S, Baeza C, Eisenberg R, Attizzani G. Transcatheter Aortic Valve Replacement in Large Annuli Valves With the Supra-Annular, Self-Expandable Evolut Platform in a Real-World Registry. Circulation Cardiovascular Interventions 2023, 16: e012623. PMID: 36943929, PMCID: PMC10022658, DOI: 10.1161/circinterventions.122.012623.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementAortic valve replacementCardiology Transcatheter Valve Therapy RegistryThoracic Surgeons/American CollegeTranscatheter Valve Therapy RegistryValve replacementAortic stenosisAmerican CollegeMultivariable Cox proportional hazards regression modelsAnnulus sizeCox proportional hazards regression modelProportional hazards regression modelsAortic valve reinterventionTricuspid aortic stenosisReal-world registrySevere aortic stenosisBetter clinical outcomesTreatment of patientsHazards regression modelsComputed tomography angiographyLarge annulusValve reinterventionCause mortalityReadmission ratesValve procedures
2022
Association between myocardial ischemia and plaque characteristics in chronic total occlusion
Cho S, Lee J, Kim H, Song H, Kim Y. Association between myocardial ischemia and plaque characteristics in chronic total occlusion. Journal Of Nuclear Cardiology 2022, 30: 388-398. PMID: 35836093, DOI: 10.1007/s12350-022-03020-6.Peer-Reviewed Original ResearchConceptsCoronary computed tomography angiographySingle-photon emission computed tomographyChronic total occlusionOccluded segmentMyocardial perfusion single-photon emission computed tomographyPerfusion single-photon emission computed tomographyTotal occlusionMyocardial ischemiaPlaque characteristicsComputed tomography angiographyLow-density plaqueEmission computed tomographyOcclusion lengthMultivariate analysisIschemiaOccluded arteryHighest proportionShort occlusionsPlaque ratioPlaque compositionOcclusionPlaqueAtherosclerotic plaquesIntermediate-densityLow volumeClinically viable myocardial CCTA segmentation for measuring vessel-specific myocardial blood flow from dynamic PET/CCTA hybrid fusion
Piccinelli M, Dahiya N, Nye J, Folks R, Cooke C, Manatunga D, Hwang D, Paeng J, Cho S, Lee J, Bom H, Koo B, Yezzi A, Garcia E. Clinically viable myocardial CCTA segmentation for measuring vessel-specific myocardial blood flow from dynamic PET/CCTA hybrid fusion. European Journal Of Hybrid Imaging 2022, 6: 4. PMID: 35165793, PMCID: PMC8844325, DOI: 10.1186/s41824-021-00122-1.Peer-Reviewed Original ResearchClinically acceptable timeCoronary computed tomography angiographyMyocardial blood flowPatient borderDC coefficientsBlood flowDice coefficientMethodsForty-three patientsAbsolute myocardial blood flowComputed tomography angiographyBackgroundPositron emission tomographyAnatomical vascular territoriesFlow measurementsMyocardial blood flow measurementsImage fusionPatients’ coronary computed tomography angiographyMasking modelResting flow valuesFlow accuracyBlood flow measurementsProcessing timeMyocardial segmentsAcceptable timeEpicardial vesselsAcceptable processing time
2021
Ipsilateral internal carotid artery web and acute ischemic stroke: A cohort study, systematic review and meta-analysis
Mac Grory B, Nossek E, Reznik ME, Schrag M, Jayaraman M, McTaggart R, de Havenon A, Yaghi S, Feng W, Furie K, Boyanpally A. Ipsilateral internal carotid artery web and acute ischemic stroke: A cohort study, systematic review and meta-analysis. PLOS ONE 2021, 16: e0257697. PMID: 34534252, PMCID: PMC8448368, DOI: 10.1371/journal.pone.0257697.Peer-Reviewed Original ResearchConceptsCarotid artery webCarotid webIschemic stroke patientsCryptogenic strokeComputed tomography angiographyStroke patientsSystematic reviewCohort studyIschemic strokeRelative riskSimilar cohortAcute ischemic stroke patientsCompelling potential mechanismsCryptogenic stroke patientsComprehensive stroke centerAcute ischemic strokeEmbolic ischemic strokeEligible patientsSecondary preventionStroke centersStroke subtypesYounger patientsPooled prevalenceTomography angiographyPatients
2020
Utility of Apical Lung Assessment on Computed Tomography Angiography as a COVID-19 Screen in Acute Stroke
Esenwa C, Lee J, Nisar T, Shmukler A, Goldman I, Zampolin R, Hsu K, Labovitz D, Altschul D, Haramati L. Utility of Apical Lung Assessment on Computed Tomography Angiography as a COVID-19 Screen in Acute Stroke. Stroke 2020, 51: 3765-3769. PMID: 33115325, PMCID: PMC7678646, DOI: 10.1161/strokeaha.120.030959.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeComputed tomography angiographyLung assessmentTomography angiographyPredictive valuePatient-reported symptomsShortness of breathCoronavirus disease 2019Self-reported clinical symptomsCOVID-19Negative predictive valuePositive predictive valueAccurate screening toolAcute strokeIschemic strokeLung findingsClinical symptomsLung apexDisease 2019Lung examAngiographyDiagnostic accuracyScreening toolPatientsSymptomsEffects of Collateral Status on Infarct Distribution Following Endovascular Therapy in Large Vessel Occlusion Stroke
Al-Dasuqi K, Payabvash S, Torres-Flores GA, Strander SM, Nguyen CK, Peshwe KU, Kodali S, Silverman A, Malhotra A, Johnson MH, Matouk CC, Schindler JL, Sansing LH, Falcone GJ, Sheth KN, Petersen NH. Effects of Collateral Status on Infarct Distribution Following Endovascular Therapy in Large Vessel Occlusion Stroke. Stroke 2020, 51: e193-e202. PMID: 32781941, PMCID: PMC7484023, DOI: 10.1161/strokeaha.120.029892.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overArterial Occlusive DiseasesCerebral InfarctionCohort StudiesCollateral CirculationComputed Tomography AngiographyEndovascular ProceduresFemaleHumansInfarction, Middle Cerebral ArteryLinear ModelsMagnetic Resonance AngiographyMaleMiddle AgedReperfusionRetrospective StudiesStrokeThrombectomyTreatment OutcomeWhite MatterConceptsLarge vessel occlusion strokeFinal infarct volumeCollateral statusPoor collateral statusFavorable outcomeInfarct distributionInfarct volumeReperfusion successIndependent predictorsOcclusion strokeInternal capsuleAnterior circulation large vessel occlusion ischemic strokeLarge vessel occlusion ischemic strokeDeep white matter tractsBaseline collateral statusBorder-zone infarctionEarly favorable outcomeEarly functional outcomesRankin Scale scoreCohort of patientsDegree of reperfusionLarge vessel occlusionComputed tomography angiographyDeep white matterMagnetic resonance imagingComputed Tomographic Angiography Assessment of Epicardial Coronary Vasoreactivity for Early Detection of Doxorubicin-Induced Cardiotoxicity
Feher A, Boutagy NE, Stendahl JC, Hawley C, Guerrera N, Booth CJ, Romito E, Wilson S, Liu C, Sinusas AJ. Computed Tomographic Angiography Assessment of Epicardial Coronary Vasoreactivity for Early Detection of Doxorubicin-Induced Cardiotoxicity. JACC CardioOncology 2020, 2: 207-219. PMID: 34396230, PMCID: PMC8352292, DOI: 10.1016/j.jaccao.2020.05.007.Peer-Reviewed Original ResearchComputed tomography angiographyEpicardial coronary diameterGlobal longitudinal strainCoronary diameterCoronary vasoreactivityLeft ventricular ejection fraction reductionVentricular ejection fraction reductionLongitudinal strainCoronary Computed Tomography AngiographyEjection fraction reductionEpicardial coronary arteriesVentricular ejection fractionDoxorubicin-Induced CardiotoxicityChronic canine modelPrevention of doxorubicinEpicardial vasodilationVasodilator responseAngiography assessmentEjection fractionCumulative dosesCoronary arteryTomography angiographyPharmacological stressorVascular toxicityVascular endothelium
2019
Increased Sensitivity of Focused Cardiac Ultrasound for Pulmonary Embolism in Emergency Department Patients With Abnormal Vital Signs
Daley JI, Dwyer KH, Grunwald Z, Shaw DL, Stone MB, Schick A, Vrablik M, Hall M, Hall J, Liteplo AS, Haney RM, Hun N, Liu R, Moore CL. Increased Sensitivity of Focused Cardiac Ultrasound for Pulmonary Embolism in Emergency Department Patients With Abnormal Vital Signs. Academic Emergency Medicine 2019, 26: 1211-1220. PMID: 31562679, DOI: 10.1111/acem.13774.Peer-Reviewed Original ResearchConceptsAbnormal vital signsComputed tomography angiographyBeats/minPulmonary embolismVital signsProspective observational multicenter cohort studyCardiac ultrasoundTricuspid annular plane systolic excursionObservational multicenter cohort studyAnnular plane systolic excursionDiagnosis of PERight ventricular dysfunctionMulticenter cohort studyRight ventricular dilationUrban academic EDEmergency department patientsEntire patient populationVital sign abnormalitiesFocused cardiac ultrasoundRapid bedside testDiagnostic test characteristicsSubstantial interobserver agreementMcConnell's signVentricular dysfunctionCohort studyTraumatic vertebral artery injury: a review of the screening criteria, imaging spectrum, mimics, and pitfalls
Sharma P, Hegde R, Kulkarni A, Sharma S, Soin P, Kochar PS, Kumar Y. Traumatic vertebral artery injury: a review of the screening criteria, imaging spectrum, mimics, and pitfalls. Polish Journal Of Radiology 2019, 84: e307-e318. PMID: 31636765, PMCID: PMC6798777, DOI: 10.5114/pjr.2019.88023.Peer-Reviewed Original ResearchTraumatic vertebral artery injuriesComputed tomography angiographyMagnetic resonance angiographyIntramural haematomaScreening criteriaVertebral artery injuryVaried clinical presentationsFlight magnetic resonance angiographyFat-saturated imagesTapered narrowingArtery injuryCraniocervical traumaClinical presentationIntimal flapDouble lumenUncommon findingVariant anatomyLuminal stenosisTomography angiographyHyperintense signalCommon findingFlow voidsResonance angiographyVessel wallHaematomaCost-Effectiveness of Computed Tomography Angiography in Management of Tiny Unruptured Intracranial Aneurysms in the United States
Wu X, Matouk CC, Mangla R, Forman HP, Gandhi D, Sanelli P, Malhotra A. Cost-Effectiveness of Computed Tomography Angiography in Management of Tiny Unruptured Intracranial Aneurysms in the United States. Stroke 2019, 50: 2396-2403. PMID: 31340732, DOI: 10.1161/strokeaha.119.025600.Peer-Reviewed Original ResearchConceptsComputed tomography angiographyUnruptured intracranial aneurysmsIntracranial aneurysmsTomography angiographyCancer riskCTA surveillanceCost-effective strategyRadiation-induced brain tumorsRadiation-induced cancer riskSubsequent magnetic resonanceBrain cancer riskBetter health outcomesAnnual rupture riskProbabilistic sensitivity analysesRupture riskLower healthcare spendingAggressive managementPatients 30Subarachnoid hemorrhageIncidental detectionPrior historyHigh riskBrain tumorsAneurysmsHealth outcomesResults From DEFUSE 3
de Havenon A, Mlynash M, Kim-Tenser MA, Lansberg MG, Leslie-Mazwi T, Christensen S, McTaggart RA, Alexander M, Albers G, Broderick J, Marks MP, Heit JJ, Investigators O. Results From DEFUSE 3. Stroke 2019, 50: 632-638. PMID: 30726184, PMCID: PMC6628906, DOI: 10.1161/strokeaha.118.023407.Peer-Reviewed Original ResearchConceptsIschemic core volumeLarge vessel occlusionEndovascular thrombectomyCollateral statusTomography angiographyFunctional independenceDEFUSE 3Poor collateralsLeptomeningeal collateralsStroke patientsVessel occlusionGood collateralsAnterior circulation large vessel occlusionBaseline ischemic core volumeSmall ischemic core volumeAcute ischemic stroke patientsDEFUSE 3 patientsIschemic stroke patientsModified Rankin ScaleStroke-related deathComputed tomography angiographyGood leptomeningeal collateralsTreatment effectsNeurological outcomePrespecified analysis
2018
Clinical Decision Support for Ordering CTA-PE Studies in the Emergency Department—A Pilot on Feasibility and Clinical Impact in a Tertiary Medical Center
Goehler A, Moore C, Manne-Goehler JM, Arango J, D'Amato L, Forman HP, Weinreb J. Clinical Decision Support for Ordering CTA-PE Studies in the Emergency Department—A Pilot on Feasibility and Clinical Impact in a Tertiary Medical Center. Academic Radiology 2018, 26: 1077-1083. PMID: 30389307, DOI: 10.1016/j.acra.2018.09.009.Peer-Reviewed Original ResearchConceptsPulmonary embolismClinical decision supportPositivity rateTertiary medical centerComputed tomography angiographyPhysician adherenceD-dimerGood discriminatory powerTomography angiographyEmergency providersClinical impactMedical CenterRisk scoreDiscriminatory powerEmbolismPatientsAngiographyComplianceStudy
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