2025
Vascular segmental exclusion for recurrent vulvar squamous cell carcinoma invading the femoral vessels
Schwartz A, Azodi M, Cardella J, Chaar C. Vascular segmental exclusion for recurrent vulvar squamous cell carcinoma invading the femoral vessels. Journal Of Vascular Surgery Cases And Innovative Techniques 2025, 11: 101753. DOI: 10.1016/j.jvscit.2025.101753.Peer-Reviewed Original ResearchRecurrent vulvar squamous cell carcinomaVulvar squamous cell carcinomaInvasive vulvar carcinomaExtensive local invasionProgression of oncological diseasesSquamous cell carcinomaLower limb ischemiaSuperficial femoral arteryVulvar carcinomaFemoral artery embolismAbdomen-pelvisUnresectable tumorsArtery embolizationCell carcinomaLeft axillaryPopliteal artery bypassWide resectionThree-month follow-upLocal invasionArtery bypassComputed tomographyFollow-upNecrotic massLimb ischemiaFemoral veinEosinophilic esophagitis manifesting as intractable hiccups in an elderly patient: a case report
Jalloul S, Salem J, Karam K, Chamoun C, Chaptini L. Eosinophilic esophagitis manifesting as intractable hiccups in an elderly patient: a case report. Journal Of Medical Case Reports 2025, 19: 99. PMID: 40045389, PMCID: PMC11884032, DOI: 10.1186/s13256-025-05044-1.Peer-Reviewed Original ResearchConceptsDiagnosis of eosinophilic esophagitisEosinophilic esophagitisEosinophil infiltrationSymptoms related to esophageal dysfunctionComputed tomography of the chestSymptoms of eosinophilic esophagitisElevated peripheral eosinophil countPeripheral eosinophil countEsophagitis treatmentRefractory hiccupsBackgroundEosinophilic esophagitisConclusionThis caseEsophageal dysfunctionCase reportWeUpper endoscopyFood impactionIntermittent dysphagiaCase reportEndoscopic findingsDistal esophagusElderly patientsEosinophil countEsophageal mucosaComputed tomographyIntractable hiccupsMorphological alterations of the thymus gland in individuals with schizophrenia
Zhao Q, Wei X, Yu W, Li X, Gao Z, Liu S, Liu Z, Wang K, Bishop J, Hu H, Luo C, Xiao Y, Hu N, Tao B, Zhu F, Gong Q, Lui S. Morphological alterations of the thymus gland in individuals with schizophrenia. Molecular Psychiatry 2025, 1-11. PMID: 40038543, DOI: 10.1038/s41380-025-02946-w.Peer-Reviewed Original ResearchAverage CT attenuationChest computed tomographyCT attenuationImmunometabolic profileThymic morphologySubtype 1Subtype 2Evidence of immunological abnormalitiesMaximal thicknessAnteroposterior distancePatient subtypesLow CT attenuationMorphological alterationsCase-control comparisonImmunological abnormalitiesThymic sizeLymphocyte countSchizophreniaComputed tomographyLipid measurementsThymus glandImmune hypothesisPatientsImmune systemSubtypesIntegration and Potential Applications of Cardiovascular Computed Tomography in Cardio-Oncology
Erbay M, Manubolu V, Stein-Merlob A, Ferencik M, Mamas M, Lopez-Mattei J, Baldassarre L, Budoff M, Yang E. Integration and Potential Applications of Cardiovascular Computed Tomography in Cardio-Oncology. Current Cardiology Reports 2025, 27: 51. PMID: 39932640, PMCID: PMC11814013, DOI: 10.1007/s11886-025-02206-x.Peer-Reviewed Original ResearchConceptsRadiation-induced cardiovascular diseaseCoronary artery diseaseCardiovascular diseaseCardiac massComputed tomographyArtery diseaseChest CT scans of patientsCT scans of patientsIncreased risk of CVDInvasive coronary angiographyRisk of cardiovascular diseaseRisk of complicationsScans of patientsCardiovascular computed tomographySeverity of cardiovascular diseaseNon-invasive imaging toolMonitoring of disease progressionManifestations of diseaseAsymptomatic patientsCardiac deteriorationIschemia evaluationCoronary angiographyPericardial diseaseCardiac changesRisk stratificationLung Cancer Screening and Incidental Findings: A Research Agenda: An Official American Thoracic Society Research Statement.
Henderson L, Kim R, Tanner N, Tsai E, Begnaud A, Dako F, Gieske M, Kallianos K, Richman I, Sakoda L, Schwartz R, Yeboah J, Fong K, Lam S, Lee P, Pasquinelli M, Smith R, Triplette M, Tanoue L, Rivera M. Lung Cancer Screening and Incidental Findings: A Research Agenda: An Official American Thoracic Society Research Statement. American Journal Of Respiratory And Critical Care Medicine 2025, 211: 436-451. PMID: 39928329, PMCID: PMC11936151, DOI: 10.1164/rccm.202501-0011st.Peer-Reviewed Original ResearchConceptsLow-dose computed tomographyManagement of incidental findingsLung cancer screeningCancer screeningThree-round modified Delphi processReporting of incidental findingsClinically significant IFsPrioritized questionsDelphi processIncidental findingClinicians' effortsMultidisciplinary panelPatient anxietyResearch questionsPotential harmLDCT examinationsCoronary artery calcificationIncreased awarenessSignificant IFsExcess costsHarmPotential benefitsArtery calcificationKnowledge gapsComputed tomographyFine‐Needle Aspiration Biopsy of Adrenal Gland Lesions: The Roles of Image Guidance, Rapid On‐Site Evaluation and Additional Tissue Sampling
Yu S, Dolezal D, Aslanian H, Cai G. Fine‐Needle Aspiration Biopsy of Adrenal Gland Lesions: The Roles of Image Guidance, Rapid On‐Site Evaluation and Additional Tissue Sampling. Cytopathology 2025 PMID: 39878416, DOI: 10.1111/cyt.13472.Peer-Reviewed Original ResearchFine-needle aspirationDiagnosis of adrenal lesionsCytological diagnostic categoriesAdrenal lesionsIndeterminate cytological diagnosisNon-diagnostic rateCytological diagnosisEndoscopic ultrasoundEUS-FNAOn-site evaluationNon-diagnosticImage guidanceComputed tomographyCT-guided fine-needle aspirationEvaluation of adrenal lesionsFine-needle aspiration diagnosisTissue samplesFine-needle aspiration proceduresLeft adrenal lesionRight adrenal lesionRapid on-site evaluationNon-ROSE groupIncrease diagnostic yieldImage guidance methodsCore tissue biopsiesDiagnosis and Management of Acute Pancreatitis
Mittal N, Oza V, Muniraj T, Kothari T. Diagnosis and Management of Acute Pancreatitis. Diagnostics 2025, 15: 258. PMID: 39941188, PMCID: PMC11816589, DOI: 10.3390/diagnostics15030258.Peer-Reviewed Original ResearchAcute pancreatitisMagnetic resonance imagingComputed tomographyRecurrence of acute pancreatitisComplications of acute pancreatitisPost-endoscopic retrograde cholangiopancreatographyDiagnosis of acute pancreatitisRate of acute pancreatitisManagement of acute pancreatitisAttended regular follow-upsAcute pancreatitis episodesEarly oral feedingPancreatic exocrine insufficiencyRegular follow-upMortality rate of acute pancreatitisAnalysis of immunoglobulinEnteral tube feedingAbdominal painExocrine insufficiencyPancreatitis episodesMetabolic panelTransabdominal ultrasoundPain controlRetrograde cholangiopancreatographySerum amylaseGross tumor volume confidence maps prediction for soft tissue sarcomas from multi-modality medical images using a diffusion model
Dong Y, Marin T, Zhuo Y, Najem E, Moteabbed M, Xing F, Beddok A, Lahoud R, Rozenblum L, Ding Z, Liu X, Grogg K, Woo J, Chen Y, Lim R, Ma C, Fakhri G. Gross tumor volume confidence maps prediction for soft tissue sarcomas from multi-modality medical images using a diffusion model. Physics And Imaging In Radiation Oncology 2025, 33: 100734. PMID: 40123775, PMCID: PMC11926426, DOI: 10.1016/j.phro.2025.100734.Peer-Reviewed Original ResearchGross tumor volumeSoft tissue sarcomasTissue sarcomasGross tumor volume delineationManual GTV delineationsMagnetic resonance imagingComputed tomographyFluorodeoxyglucose positron emission tomographyGTV delineationT1-weighted magnetic resonance imagingSingle-modePositron emission tomographyMulti-modal medical imagesTumor volumeIntra-reader variabilityFDG-PETTreatment planningSarcomaEmission tomographyImaging modalitiesResonance imagingDiffusion modelDice indexReader variabilityPatients
2024
Optimizing Automated Hematoma Expansion Classification from Baseline and Follow-Up Head Computed Tomography
Tran A, Desser D, Zeevi T, Karam G, Zietz J, Dell’Orco A, Chen M, Malhotra A, Qureshi A, Murthy S, Majidi S, Falcone G, Sheth K, Nawabi J, Payabvash S. Optimizing Automated Hematoma Expansion Classification from Baseline and Follow-Up Head Computed Tomography. Applied Sciences 2024, 15: 111. PMID: 40046237, PMCID: PMC11882137, DOI: 10.3390/app15010111.Peer-Reviewed Original ResearchIntracerebral hemorrhageHematoma expansionFollow-up CT scansFollow-up head computed tomographyPredictors of poor outcomeDeep learning classification modelFollow-up scansHead computed tomographyFalse-negative resultsHematoma segmentationAutomated segmentationMulticentre cohortCT scanValidation cohortPoor outcomeComputed tomographyFollow-upClassification modelOptimizational methodHematomaAnnotationMachine Learning Models for 3-Month Outcome Prediction Using Radiomics of Intracerebral Hemorrhage and Perihematomal Edema from Admission Head Computed Tomography (CT)
Dierksen F, Sommer J, Tran A, Lin H, Haider S, Maier I, Aneja S, Sanelli P, Malhotra A, Qureshi A, Claassen J, Park S, Murthy S, Falcone G, Sheth K, Payabvash S. Machine Learning Models for 3-Month Outcome Prediction Using Radiomics of Intracerebral Hemorrhage and Perihematomal Edema from Admission Head Computed Tomography (CT). Diagnostics 2024, 14: 2827. PMID: 39767188, PMCID: PMC11674633, DOI: 10.3390/diagnostics14242827.Peer-Reviewed Original ResearchIntegrated discrimination indexNet reclassification indexPerihematomal edemaHead computed tomographyIntracerebral hemorrhageComputed tomographyClinical variablesClinical predictors of poor outcomeOutcome predictionAcute supratentorial intracerebral hemorrhageAdmission head computed tomographyRadiomic featuresNon-contrast head computed tomographyPredictors of poor outcomeModified Rankin Scale scoreIntracerebral hemorrhage scoreSupratentorial intracerebral hemorrhageIntracerebral hemorrhage patientsClinical risk factorsRankin Scale scoreReceiver operating characteristic areaOperating characteristics areaSecondary brain injuryHematoma evacuationPatient selectionDiagnostic performance of neural network algorithms in skull fracture detection on CT scans: a systematic review and meta-analysis
Sharifi G, Hajibeygi R, Zamani S, Easa A, Bahrami A, Eshraghi R, Moafi M, Ebrahimi M, Fathi M, Mirjafari A, Chan J, Dixe de Oliveira Santo I, Anar M, Rezaei O, Tu L. Diagnostic performance of neural network algorithms in skull fracture detection on CT scans: a systematic review and meta-analysis. Emergency Radiology 2024, 32: 97-111. PMID: 39680295, DOI: 10.1007/s10140-024-02300-7.Peer-Reviewed Original ResearchConceptsConvolutional neural networkArea under the receiver operating characteristic curveConvolutional neural network modelCT scanSkull fractureComputed tomographyDeep learningProspective clinical trialMeta-analysisReceiver operating characteristic curvePublication biasSkull fracture detectionSystematic reviewNeural network algorithmDetecting skull fracturesImprove diagnosis accuracyDiagnostic hurdlesShortage of radiologistsAutomated diagnostic toolTransfer learningDiagnostic performanceDiagnostic accuracyClinical trialsModel architectureNeural networkA Hybrid Transformer-Convolutional Neural Network for Segmentation of Intracerebral Hemorrhage and Perihematomal Edema on Non-Contrast Head Computed Tomography (CT) with Uncertainty Quantification to Improve Confidence
Tran A, Desser D, Zeevi T, Abou Karam G, Dierksen F, Dell'Orco A, Kniep H, Hanning U, Fiehler J, Zietz J, Sanelli P, Malhotra A, Duncan J, Aneja S, Falcone G, Qureshi A, Sheth K, Nawabi J, Payabvash S. A Hybrid Transformer-Convolutional Neural Network for Segmentation of Intracerebral Hemorrhage and Perihematomal Edema on Non-Contrast Head Computed Tomography (CT) with Uncertainty Quantification to Improve Confidence. Bioengineering 2024, 11: 1274. PMID: 39768092, PMCID: PMC11672977, DOI: 10.3390/bioengineering11121274.Peer-Reviewed Original ResearchNon-contrast head computed tomographyPerihematomal edemaHead computed tomographyIntracerebral hemorrhageComputed tomographyVolume similarityUniversity Medical Center Hamburg-EppendorfSecondary brain injuryYale cohortInfratentorial locationMulticentre trialCT scanTreatment planningNon-contrastHamburg-EppendorfImaging markersHemorrhagic strokeHemorrhageEdemaCohortBrain injuryDice coefficientScanning the aged to minimize missed injury: An Eastern Association for the Surgery of Trauma multicenter study
Ho V, Kishawi S, Hill H, O'Brien J, Ratnasekera A, Seng S, Ton T, Butts C, Muller A, Diaz B, Baltazar G, Petrone P, Pacheco T, Morrissey S, Chung T, Biller J, Jacobson L, Williams J, Nebughr C, Udekwu P, Tann K, Piehl C, Veatch J, Capasso T, Kuncir E, Kodadek L, Miller S, Altan D, Mentzer C, Damiano N, Burke R, Earley A, Doris S, Villa E, Wilkinson M, Dixon J, Wu E, Moncrief M, Palmer B, Herzing K, Egodage T, Williams J, Haan J, Lightwine K, Colling K, Harry M, Nahmias J, Tay-Lasso E, Cuschieri J, Hinojosa C, Claridge J. Scanning the aged to minimize missed injury: An Eastern Association for the Surgery of Trauma multicenter study. Journal Of Trauma And Acute Care Surgery 2024, 98: 101-110. PMID: 38797882, PMCID: PMC11599468, DOI: 10.1097/ta.0000000000004390.Peer-Reviewed Original ResearchNegative predictive valueHigh-risk criteriaBlunt trauma patientsPan-scanTorso CTMissed injuriesComputed tomographyTrauma patientsClinical algorithmInjury diagnosisIncidence of blunt traumaPositive clinical findingsPhysical exam findingsLack of evidence-based guidanceMulticenter studyClinical findingsProspective validationExam findingsEvidence-based guidanceBlunt traumaClinical useGeriatric patientsPatientsPredictive valueTrauma populationUnnecessary Scans Lead to Unnecessary Re-scans: Evaluating Clinical Management of Low and Intermediate Risk Pediatric Traumatic Brain Injuries
Rivero R, Curran I, Hellmann Z, Carroll M, Hornick M, Solomon D, DiLuna M, Morrell P, Christison-Lagay E. Unnecessary Scans Lead to Unnecessary Re-scans: Evaluating Clinical Management of Low and Intermediate Risk Pediatric Traumatic Brain Injuries. Journal Of Pediatric Surgery 2024, 60: 162097. PMID: 39693726, DOI: 10.1016/j.jpedsurg.2024.162097.Peer-Reviewed Original ResearchPediatric Emergency Care Applied Research NetworkPECARN guidelinesPediatric Emergency Care Applied Research Network criteriaClinically important traumatic brain injuryComputed tomographyRisk patientsCross-sectional imagingIntermediate risk group patientsHead traumaIntracranial injuryIntermediate risk patientsRisk group patientsLow-risk injuriesLow-risk patientsRetrospective cohort studyClinically significant progressionEvaluate clinical managementIncreased hospital costsMild head traumaPenetrating head traumaLength of stayTraumatic brain injuryNon-accidental traumaBrain injuryRetrospective reviewCT-Less Whole-Body Bone Segmentation of PET Images Using a Multimodal Deep Learning Network
Bao N, Zhang J, Li Z, Wei S, Zhang J, Greenwald S, Onofrey J, Lu Y, Xu L. CT-Less Whole-Body Bone Segmentation of PET Images Using a Multimodal Deep Learning Network. IEEE Journal Of Biomedical And Health Informatics 2024, 29: 1151-1164. PMID: 40030243, DOI: 10.1109/jbhi.2024.3501386.Peer-Reviewed Original ResearchPositron emission tomographyMultimodal fusion modulePositron emission tomography imagingMultimodal fusion networkAttenuation mapDice similarity coefficientFusion moduleFusion networkEncoder RepresentationsEncoder branchesCT imagesTraining dataComputed tomographyTumor analysisTracer activityModality imagesMultimodal deep learning networkPET imagingBone segmentsSqueeze-and-excitationBone cancerPositron emission tomography informationCT-based approachDeep learning networkImprove segmentation performanceConstruction and performance of a clinical prediction rule for ureteral stone without the use of race or ethnicity: A new STONE score
Moore C, Gross C, Hart L, Molinaro A, Rhodes D, Singh D, Baloescu C. Construction and performance of a clinical prediction rule for ureteral stone without the use of race or ethnicity: A new STONE score. Journal Of The American College Of Emergency Physicians Open 2024, 5: e13324. PMID: 39524039, PMCID: PMC11543628, DOI: 10.1002/emp2.13324.Peer-Reviewed Original ResearchClinical prediction ruleArea under the receiver operating characteristic curveSTONE scoreMultivariate logistic regressionUreteral stonesComputed tomographyPrediction ruleUncomplicated renal colicKidney stonesReceiver operating characteristic curveLogistic regressionNon-black raceDiagnosis of kidney stonesGross hematuriaMicroscopic hematuriaRenal colicPotential adverse effectsDiagnostic accuracyHematuriaClinical algorithmMale genderProspective dataClinical accuracyRetrospective dataCharacteristic curveMassive thymic hyperplasia in a toddler masquerading as a loculated pleural effusion: A case report
Zolfaghari E, Shaughnessy M, Wu H, Caty M, Christison-Lagay E, Hornick M. Massive thymic hyperplasia in a toddler masquerading as a loculated pleural effusion: A case report. Journal Of Pediatric Surgery Case Reports 2024, 110: 102885. DOI: 10.1016/j.epsc.2024.102885.Peer-Reviewed Original ResearchMassive thymic hyperplasiaChest X-rayThymic hyperplasiaCase reportComputed tomographyDifferential diagnosis of pediatric patientsSurveillance chest x-raysDiagnosis of pediatric patientsTrue thymic hyperplasiaRecurrent respiratory distressPost-operative coursePercutaneous core biopsyLoculated pleural effusionHistory of multiple admissionsPersistent respiratory symptomsSurgical resectionCore biopsyParapneumonic effusionPediatric patientsAbnormal findingsPleural effusionRight thoracotomyRare conditionRight hemithoraxSuspected pneumoniaRecommended guidelines for screening for underlying malignancy in extramammary Paget's disease based on anatomic subtype
Kibbi N, Owen J, Worley B, Alam M, Group E, Wang J, Harikumar V, Downing M, Aasi S, Aung P, Barker C, Bolotin D, Bordeaux J, Cartee T, Chandra S, Cho N, Choi J, Chung K, Cliby W, Dorigo O, Eisen D, Fujisawa Y, Golda N, Halfdanarson T, Iavazzo C, Jiang S, John E, Kanitakis J, Keimig E, Khan A, Linos E, Kim J, Kuzel T, Lawrence N, Leitao M, MacLean A, Maher I, Mittal B, Nehal K, Ozog D, Pettaway C, Rajan N, Ross J, Rossi A, Servaes S, Solomon M, Thomas V, Tolia M, Voelzke B, Waldman A, Wong M, Zhou Y, Brackett A, Poon E, Ahmed A. Recommended guidelines for screening for underlying malignancy in extramammary Paget's disease based on anatomic subtype. Journal Of The American Academy Of Dermatology 2024, 92: 261-268. PMID: 39401611, DOI: 10.1016/j.jaad.2024.07.1531.Peer-Reviewed Original ResearchExtramammary Paget's diseaseSecondary extramammary Paget's diseaseVulvar extramammary Paget diseasePerianal extramammary Paget's diseaseUrine cytologyAnatomic subtypesComputed tomographyPaget's diseaseProstate-specific antigen testingHigh-risk featuresOrgan-specific testsMultidisciplinary expert panelUnderlying malignancySystematic follow-upFollow-upAdenocarcinomaAntigen testAnatomical locationInclusion criteriaCytologyRetrospective dataScreening testSubtypesScreening algorithmRecommendation statementsHeart lung axis in acute pulmonary embolism: Role of CT in risk stratification
Friedman R, Haramati L, Christian T, Sokol S, Alis J. Heart lung axis in acute pulmonary embolism: Role of CT in risk stratification. Clinical Imaging 2024, 116: 110311. PMID: 39413674, DOI: 10.1016/j.clinimag.2024.110311.Peer-Reviewed Original ResearchPathophysiology of pulmonary embolismRisk stratificationPulmonary embolismComputed tomographyRight ventricular (RV) dysfunctionRisk stratification of acute PEIndicator of RV dysfunctionRV/LV diameter ratioAcute pulmonary embolismLeft atrial volumeReview current guidelinesCause of mortalityRV dysfunctionAcute PEAtrial volumeCT findingsClot burdenCardiopulmonary reserveCurrent guidelinesLung axisClot locationPatient managementPatient populationRadiologist's reportPredictive value8740 Visceral Adipose Tissue Assessment in Patients With Mild Autonomous Cortisol Secretion Using Dual-Energy X-Ray Absorptiometry: A Cross-Sectional Study
Saini J, Zhang C, Fell V, Atkinson E, Achenbach S, Bancos I. 8740 Visceral Adipose Tissue Assessment in Patients With Mild Autonomous Cortisol Secretion Using Dual-Energy X-Ray Absorptiometry: A Cross-Sectional Study. Journal Of The Endocrine Society 2024, 8: bvae163.321. PMCID: PMC11454869, DOI: 10.1210/jendso/bvae163.321.Peer-Reviewed Original ResearchDual-energy X-ray absorptiometryVisceral adipose tissueAutonomous cortisol secretionX-ray absorptiometryFat massReference subjectsLean massComputed tomographyFull-body DXA scanMild autonomous cortisol secretionVisceral adipose tissue assessmentDual-energy X-ray absorptiometry scanCortisol secretionAssociated with increased visceral adiposityFollow-up of patientsSingle-center cross-sectional studyCompared to reference subjectsDual-energyBMI-adjusted analysisAndroid fat massCross-sectional study of adultsDexamethasone suppression testGynoid fat massPost-DST cortisolBody composition measurements
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