2023
Lyme Carditis in the Pediatric Population
Beach C, Vinocur J. Lyme Carditis in the Pediatric Population. 2023, 111-119. DOI: 10.1007/978-3-031-41169-4_11.Peer-Reviewed Original ResearchHigh-grade AV blockTemporary transvenous pacingPediatricPediatric patientsLyme carditisHemodynamic instabilityAntibiotic therapyPediatric populationPR prolongationTransvenous pacingAV blockCommon manifestationConduction abnormalitiesTimely administrationCarditisFull recoveryPatientsDiseaseGreat majorityAccompanying increaseTherapyPacingAbnormalitiesSuspicionAdministrationProlongationImaging Findings on Head Computed Tomography Scans in Victims of Intimate Partner Violence
Watane G, Tang A, Thomas R, Park H, Gujrathi R, Gosangi B, Khurana B. Imaging Findings on Head Computed Tomography Scans in Victims of Intimate Partner Violence. Journal Of Computer Assisted Tomography 2023, 47: 307-314. PMID: 36790916, DOI: 10.1097/rct.0000000000001427.Peer-Reviewed Original ResearchConceptsSoft tissue injuriesHead CTInjury visitsIntimate partner violenceTissue injurySubsequent injuryHead computed tomography (CT) scanLeft-sided injuriesInstitutional review board-approved retrospective analysisTime of injurySoft-tissue swellingComputed tomography scanConcomitant injuriesBilateral injuryRadiological findingsImaging findingsStudy cohortSubdural hematomaUnique patientsInjury patternsMean ageCommon manifestationHead injuryInjury typePrior injury
2021
Absence seizures and their relationship to depression and anxiety: Evidence for bidirectionality
Gruenbaum BF, Sandhu MRS, Bertasi RAO, Bertasi TGO, Schonwald A, Kurup A, Gruenbaum SE, Freedman IG, Funaro MC, Blumenfeld H, Sanacora G. Absence seizures and their relationship to depression and anxiety: Evidence for bidirectionality. Epilepsia 2021, 62: 1041-1056. PMID: 33751566, PMCID: PMC8443164, DOI: 10.1111/epi.16862.Peer-Reviewed Original ResearchConceptsAbsence seizuresMood disordersChildhood epilepsyCommon manifestationInclusion criteriaEffective treatmentGenetic predispositionGreater oddsAnimal modelsAnatomical pathwaysSystematic reviewDepressionShort lossDisordersPatientsBidirectional relationshipSeizuresCurrent literatureAnxietySocial impairmentFurther researchReviewEpilepsyStrong correlationImpairment
2020
SARS-CoV-2 pathophysiology and its clinical implications: An integrative overview of the pharmacotherapeutic management of COVID-19
Tsatsakis A, Calina D, Falzone L, Petrakis D, Mitrut R, Siokas V, Pennisi M, Lanza G, Libra M, Doukas SG, Doukas PG, Kavali L, Bukhari A, Gadiparthi C, Vageli DP, Kofteridis DP, Spandidos DA, Paoliello MMB, Aschner M, Docea AO. SARS-CoV-2 pathophysiology and its clinical implications: An integrative overview of the pharmacotherapeutic management of COVID-19. Food And Chemical Toxicology 2020, 146: 111769. PMID: 32979398, PMCID: PMC7833750, DOI: 10.1016/j.fct.2020.111769.Peer-Reviewed Original ResearchConceptsAcute respiratory distress syndromeClinical symptomsLife-threatening acute respiratory distress syndromeCOVID-19SARS-CoV-2 infectionPeripheral neurological manifestationsSARS-CoV-2 pathophysiologyAcute respiratory distressRespiratory distress syndromeCOVID-19 infectionSpecific therapeutic managementSARS-CoV-2 virusSARS-CoV-2Present reviewPharmacotherapeutic managementGastrointestinal symptomsRenal dysfunctionDistress syndromeNeurological manifestationsRespiratory distressMild diseaseTherapeutic managementHealthy patientsCancer patientsCommon manifestation
2019
Is There Equipoise Regarding the Optimal Medical Treatment of Patients with Asymptomatic White Matter Hyperintensities?
de Havenon A, Prabhakaran S, Turan T, Gottesman R, Yeatts S, Rost N. Is There Equipoise Regarding the Optimal Medical Treatment of Patients with Asymptomatic White Matter Hyperintensities? Journal Of Stroke And Cerebrovascular Diseases 2019, 28: 104371. PMID: 31495669, PMCID: PMC8015436, DOI: 10.1016/j.jstrokecerebrovasdis.2019.104371.Peer-Reviewed Original ResearchMeSH KeywordsAntihypertensive AgentsAsymptomatic DiseasesAttitude of Health PersonnelDisease ProgressionHealth Care SurveysHealth Knowledge, Attitudes, PracticeHumansHydroxymethylglutaryl-CoA Reductase InhibitorsLeukoencephalopathiesNeurologistsPlatelet Aggregation InhibitorsPractice Patterns, Physicians'Therapeutic EquipoiseTreatment OutcomeConceptsAsymptomatic white matter hyperintensitiesWhite matter hyperintensitiesOptimal medical treatmentMatter hyperintensitiesMedical treatmentCognitive impairmentIntensive Blood Pressure ReductionNeurologists' attitudesBlood pressure targetsStroke prevention therapyBlood pressure reductionOptimal medical managementRegional coordinating centersMild cognitive impairmentStatin therapyIschemic strokeMicrovascular diseasePressure targetsPrevention therapyClinical outcomesFunctional disabilityMedical managementPatient populationCommon manifestationWMH progressionMolecular Testing on Pleural Fluid Samples
Oh S, Ronaghi R, Cai G. Molecular Testing on Pleural Fluid Samples. Seminars In Respiratory And Critical Care Medicine 2019, 40: 340-346. PMID: 31525809, DOI: 10.1055/s-0039-1695702.Peer-Reviewed Original ResearchConceptsPleural fluid analysisPleural effusionFluid analysisMalignant diseasePleural fluidMalignant pleural effusionPleural fluid samplesRoutine thoracentesisNonmalignant diseasesCommon manifestationAppropriate stagingCytologic evaluationSignificant prognosticTherapeutic implicationsMolecular testingEffusionTreatment implicationsDiseaseFluid samplesSignificant numberLow sensitivityThoracentesisEtiologyStagingCancerA Unique Case of Complete Atrioventricular Block Rapidly Progressing to Diastolic and Systolic Dysfunction in Cardiac Sarcoidosis
Mbachi C, Ajiboye O, Ezegwu O, Mba B. A Unique Case of Complete Atrioventricular Block Rapidly Progressing to Diastolic and Systolic Dysfunction in Cardiac Sarcoidosis. Case Reports In Medicine 2019, 2019: 4341098. PMID: 30956665, PMCID: PMC6431385, DOI: 10.1155/2019/4341098.Peer-Reviewed Original ResearchCardiac sarcoidosisAtrioventricular blockSystolic dysfunctionMultisystem granulomatous diseaseComplete atrioventricular blockComplete heart blockSudden cardiac deathGranuloma infiltrationCardiac deathExtracardiac manifestationsHeart blockUnknown etiologyCommon manifestationGranulomatous diseaseSarcoidosisHigh indexUnique caseDiastolicDysfunctionDiseaseManifestationsPatientsLungEtiologySuspicion
2017
Pedophilia-Themed Obsessive–Compulsive Disorder: Assessment, Differential Diagnosis, and Treatment with Exposure and Response Prevention
Bruce SL, Ching THW, Williams MT. Pedophilia-Themed Obsessive–Compulsive Disorder: Assessment, Differential Diagnosis, and Treatment with Exposure and Response Prevention. Archives Of Sexual Behavior 2017, 47: 389-402. PMID: 28822003, DOI: 10.1007/s10508-017-1031-4.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderMental health professionalsResponse preventionPedophilic disorderHealth professionalsIntrusive thoughtsExcessive worryCompulsive disorderAspects of exposureImproper interventionFearDisordersClientsChildrenProfessionalsCommon manifestationDifferential diagnosisSpecific formAnxietyObsessiveWorryPedophiliaCompulsionObsessionSymptoms
2016
Aplastic Anemia and MDS International Foundation (AAMDSIF): Bone marrow failure disease scientific symposium 2016
Zeidan AM, Battiwalla M, Berlyne D, Winkler T. Aplastic Anemia and MDS International Foundation (AAMDSIF): Bone marrow failure disease scientific symposium 2016. Leukemia Research 2016, 53: 8-12. PMID: 27923195, PMCID: PMC7731993, DOI: 10.1016/j.leukres.2016.11.011.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsBone marrow failure syndromesMDS International FoundationAplastic anemiaPeripheral blood cytopeniasAcute myelogenous leukemiaMarrow failure syndromesBlood cytopeniasCommon manifestationIneffective hematopoiesisMyelogenous leukemiaFailure syndromeClinical implicationsHematopoietic stem cell compartmentStem cell compartmentPatientsAnemiaCell compartmentFamily membersIndependent nonprofit organizationInternational FoundationCytopeniasSyndromePathogenesisLeukemiaCytomegalovirus appendicitis in an immunocompetent host
Canterino JE, McCormack M, Gurung A, Passarelli J, Landry ML, Golden M. Cytomegalovirus appendicitis in an immunocompetent host. Journal Of Clinical Virology 2016, 78: 9-11. PMID: 26942831, DOI: 10.1016/j.jcv.2016.02.011.Peer-Reviewed Case Reports and Technical NotesConceptsImmune-compromising conditionsEnd-organ diseaseCommon viral pathogensCMV appendicitisCytomegalovirus appendicitisMononucleosis syndromeImmunocompetent hostsImmunocompetent individualsAsymptomatic infectionCommon manifestationHealthy individualsViral pathogensAppendicitisCytomegalovirusPatientsSyndromeInfectionDiseaseIndividuals
2015
Isolated vocal tremor as a focal phenotype of essential tremor: a retrospective case review
Patel A, Frucht SJ. Isolated vocal tremor as a focal phenotype of essential tremor: a retrospective case review. Journal Of Clinical Movement Disorders 2015, 2: 4. PMID: 26788340, PMCID: PMC4711152, DOI: 10.1186/s40734-015-0016-5.Peer-Reviewed Original ResearchVocal tremorFamily historyRetrospective case reviewCurrent diagnostic criteriaLeast mild improvementSodium oxybateSymptom onsetCommon medicationsInitial visitRetrospective reviewTremor improvementClinical syndromeCommon manifestationPrimary diagnosisClinical trialsAction tremorMild improvementVoice disturbanceCommon conditionLimb tremorDiagnostic criteriaAverage ageLower limbsPatientsAlcohol consumption
2012
Optic pathway glioma as part of a constitutional mismatch‐repair deficiency syndrome in a patient meeting the criteria for neurofibromatosis type 1
Yeung JT, Pollack IF, Shah S, Jaffe R, Nikiforova M, Jakacki RI. Optic pathway glioma as part of a constitutional mismatch‐repair deficiency syndrome in a patient meeting the criteria for neurofibromatosis type 1. Pediatric Blood & Cancer 2012, 60: 137-139. PMID: 22848017, DOI: 10.1002/pbc.24254.Peer-Reviewed Original ResearchConceptsOptic pathway gliomasNeurofibromatosis type 1NF-1Constitutional mismatch repair deficiency syndromeType 1Multiple colonic polypsBi-allelic lossMismatch repair genesConstitutional mismatchCommon manifestationDeficiency syndromeLait spotsDiagnostic criteriaBone marrowColonic polypsHigher likelihoodAffected individualsPatientsPhenotypic featuresRepair genesGliomasBiallelic deletionBowelMalignancySyndrome
2007
Septectomy and Septal Dermoplasty for the Treatment of Severe Transfusion-Dependent Epistaxis in Patients with Hereditary Hemorrhagic Telangiectasia and Septal Perforation
Lesnik GT, Ross DA, Henderson KJ, Joe JK, Leder SB, White RI. Septectomy and Septal Dermoplasty for the Treatment of Severe Transfusion-Dependent Epistaxis in Patients with Hereditary Hemorrhagic Telangiectasia and Septal Perforation. American Journal Of Rhinology And Allergy 2007, 21: 312-315. PMID: 17621815, DOI: 10.2500/ajr.2007.21.3017.Peer-Reviewed Original ResearchConceptsHereditary hemorrhagic telangiectasiaSeptal dermoplastySeptal perforationQuality of lifeTransfusion requirementsHHT patientsHemorrhagic telangiectasiaMainstay of treatmentCentral nervous systemAutosomal dominant disorderMonopolar cauterizationGraft uptakeCommon manifestationMucocutaneous tissuesSubjective improvementEffective treatmentEpistaxisVisceral organsPatientsSeptectomyNervous systemAbnormal angiogenesisPatient resultsTelangiectasia formationCombined procedure
2004
The Relationship Between Number of Medications and Weight Loss or Impaired Balance in Older Adults
Agostini JV, Han L, Tinetti ME. The Relationship Between Number of Medications and Weight Loss or Impaired Balance in Older Adults. Journal Of The American Geriatrics Society 2004, 52: 1719-1723. PMID: 15450051, DOI: 10.1111/j.1532-5415.2004.52467.x.Peer-Reviewed Original ResearchConceptsImpaired balanceOdds ratioWeight lossCumulative medication exposureNumber of medicationsAdjusted odds ratioNumber of hospitalizationsAdverse drug effectsCommunity-dwelling residentsAdverse drug outcomesTotal drug useMedication exposureMore medicationsIndividual medicationsCommon manifestationChronic diseasesChronic illnessLongitudinal cohortMedicationsDepressive symptomsDrug effectsCognitive impairmentDrug useHearing impairmentExtensive adjustment
2003
Borrelia burgdorferi transcriptome in the central nervous system of non-human primates
Narasimhan S, Camaino M, Liang FT, Santiago F, Laskowski M, Philipp MT, Pachner AR, Radolf JD, Fikrig E. Borrelia burgdorferi transcriptome in the central nervous system of non-human primates. Proceedings Of The National Academy Of Sciences Of The United States Of America 2003, 100: 15953-15958. PMID: 14671329, PMCID: PMC307674, DOI: 10.1073/pnas.2432412100.Peer-Reviewed Original ResearchConceptsNon-human primate modelB. burgdorferiEffect of dexamethasoneCentral nervous systemHost metabolic pathwaysNon-human primatesNeurological symptomsPaucibacillary natureCNS milieuImmune statusCommon manifestationPrimate modelNervous systemExpression profilesLyme diseaseHost factorsHeart tissueGene expressionB. burgdorferi transcriptomeBorrelia burgdorferiNHPNeuroborreliosisImmunocompetentVivo gene expressionBurgdorferi
1993
Primary tumours of the duodenum
Kaminski N, Shaham D, Eliakim R. Primary tumours of the duodenum. Postgraduate Medical Journal 1993, 69: 136-138. PMID: 8506195, PMCID: PMC2399609, DOI: 10.1136/pgmj.69.808.136.Peer-Reviewed Original ResearchConceptsIron deficiency anemiaDeficiency anemiaChronic iron deficiency anemiaSevere iron deficiency anemiaPrimary duodenal tumorThorough gastrointestinal evaluationUseful diagnostic toolGastrointestinal evaluationDuodenal tumorsCurable diseaseCurative procedureCommon manifestationPrimary tumorMalignant tumorsSmall intestineTumorsPatientsAnemiaDiagnostic toolEndoscopyDuodenumDiseaseDiagnosisComplaintsIntestine
1984
Laboratory diagnosis of herpes simplex virus type 1 and type 2 infections
Hsiung GD, Landry ML, Mayo DR, Fong C. Laboratory diagnosis of herpes simplex virus type 1 and type 2 infections. Clinics In Dermatology 1984, 2: 67-82. PMID: 6100717, DOI: 10.1016/0738-081x(84)90067-1.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, MonoclonalAntibodies, ViralCells, CulturedCytopathogenic Effect, ViralDNA Restriction EnzymesFluorescent Antibody TechniqueHerpes GenitalisHerpes LabialisHerpes SimplexHumansImmunoenzyme TechniquesInclusion Bodies, ViralMicroscopy, ElectronNucleic Acid HybridizationSimplexvirusSpecimen HandlingVirionConceptsHerpes simplex virusHSV infectionHSV-2Virus isolationRecurrence of diseaseCommon viral infectionsEffective antiviral therapyType 2 infectionHerpes simplex virus type 1Simplex virus type 1HSV-1 infectionVirus type 1Fever blistersHSV isolationHerpetic lesionsAntiviral therapyClinical findingsGenital lesionsCommon manifestationDrug reactionsAllergic reactionsSevere diseaseGenital areaSimplex virusInfection results
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