2024
Electrochemotherapy in the Locoregional Treatment of Metastatic Colorectal Liver Metastases: A Systematic Review
Barbieri P, Posa A, Lancellotta V, Madoff D, Maresca A, Cornacchione P, Tagliaferri L, Iezzi R. Electrochemotherapy in the Locoregional Treatment of Metastatic Colorectal Liver Metastases: A Systematic Review. Current Oncology 2024, 31: 7403-7413. PMID: 39590176, PMCID: PMC11592455, DOI: 10.3390/curroncol31110546.Peer-Reviewed Original ResearchConceptsCRC liver metastasesLiver metastasesColorectal cancerComplete responseOverall survivalProgressive diseaseInclusion criteriaResection of CRC liver metastasesTreatment of CRC liver metastasisColorectal cancer liver metastasesSystematic searches of PubMedFrequent liver metastasesMedian overall survivalSecondary liver cancerFollow-up durationColorectal Liver MetastasesMultiple risk factorsCancer-related mortalitySearch of PubMedECT-related complicationsEvidence qualityLocoregional treatmentSurgical resectionIdentified articlesGRADE approach
2015
Comparative Effectiveness of Hepatic Artery Based Therapies for Unresectable Colorectal Liver Metastases: A Meta-Analysis
Zacharias A, Jayakrishnan T, Rajeev R, Rilling W, Thomas J, George B, Johnston F, Gamblin T, Turaga K. Comparative Effectiveness of Hepatic Artery Based Therapies for Unresectable Colorectal Liver Metastases: A Meta-Analysis. PLOS ONE 2015, 10: e0139940. PMID: 26448327, PMCID: PMC4598149, DOI: 10.1371/journal.pone.0139940.Peer-Reviewed Original ResearchConceptsHepatic arterial infusionTranscatheter arterial chemoembolizationColorectal Liver MetastasesSystemic therapyOverall survivalHepatic arterial infusion groupTranscatheter arterial chemoembolization groupLiver MetastasesConcurrent systemic therapyMedian overall survivalMeta-analysisMedian OSSystemic chemotherapyArterial chemoembolizationTumor responseTreatment toxicityArterial infusionFirst-lineSurvival outcomesRadioembolizationHepatic arteryPrimary outcomeSecondary outcomesTherapyPatients
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