2025
Common Cryoneurolysis Targets in Pain Management: Indications, Critical Anatomy, and Potential Complications
Sailer A, Latich I, Levey A. Common Cryoneurolysis Targets in Pain Management: Indications, Critical Anatomy, and Potential Complications. Seminars In Interventional Radiology 2025, 42: 205-212. PMCID: PMC12077947, DOI: 10.1055/s-0045-1804492.Peer-Reviewed Original ResearchQuality of lifePain managementCombination of therapiesImprove quality of lifeIncreased healthcare costsOpioid consumptionAdjunctive therapyHealthcare costsPatient's painUncontrolled painPhysical sufferingPainPotential complicationsAnatomical considerationsCryoneurolysisAbstract PainImprove qualityPatient outcomesPatientsClinical settingPerson's abilityCritical anatomyPatient pathologyTherapyPersonsEstimated Effectiveness of Nirsevimab Against Respiratory Syncytial Virus
Xu H, Aparicio C, Wats A, Araujo B, Pitzer V, Warren J, Shapiro E, Niccolai L, Weinberger D, Oliveira C. Estimated Effectiveness of Nirsevimab Against Respiratory Syncytial Virus. JAMA Network Open 2025, 8: e250380. PMID: 40063022, PMCID: PMC11894488, DOI: 10.1001/jamanetworkopen.2025.0380.Peer-Reviewed Original ResearchConceptsRSV-positive casesCase-control studyRSV infectionLRTI-associated hospitalizationsWeeks postimmunizationLong-acting monoclonal antibodiesTest-negative case-control studyClinical settingRespiratory syncytial virusMultivariate logistic regressionYale New Haven Health SystemRSV diseaseEmergency department dataState immunization registryRSV seasonSyncytial virusNirsevimabPolymerase chain reactionClinical trialsLRTIInfantsPotential confoundersMonoclonal antibodiesBroader outcomesDisease severityStandard to Handheld: A New Wave in Thoracic Ultrasound and Patient Care—A Direct Comparison of Portable Handheld Against Standard in Thoracic Ultrasound
Halim D, Kelly A, Hayes J, Bennett K, Tzouvelekis A, Ampazis D, Sampsonas F. Standard to Handheld: A New Wave in Thoracic Ultrasound and Patient Care—A Direct Comparison of Portable Handheld Against Standard in Thoracic Ultrasound. Medicina 2025, 61: 313. PMID: 40005430, PMCID: PMC11857366, DOI: 10.3390/medicina61020313.Peer-Reviewed Original ResearchConceptsLevels of experienceNon-inferiorityPortable ultrasound deviceOverall image qualityLung pathologyUltrasound deviceInterquartile rangeRespiratory departmentThoracic ultrasoundAnatomical visualizationHandheld ultrasound devicePatient careImprove healthcareOperator's level of experienceNo significant differenceLikert scaleTrainee levelStatistically significant variablesDiagnostic accuracyClinical decisionsOverall perceptionOnline questionnaireClinical utilityMedian rateClinical settingOpen Access: Addressing dissociation symptoms with trauma-focused mentalization-based treatment
Rüfenacht E, Shaverin L, Stubley J, Smits M, Bateman A, Fonagy P, Luyten P. Open Access: Addressing dissociation symptoms with trauma-focused mentalization-based treatment. 2025, 173-197. DOI: 10.4324/9781003560616-8.Peer-Reviewed Original ResearchMentalization-based treatmentDissociative symptomsHistory of traumatic experiencesPost-traumatic stress symptomsExpressions of dissociationMental health careMentalization theoryStress symptomsTraumatic experiencesTreatment approachesSymptomsMentalTherapeutic objectivesHealth careClinical settingClinical symptomsAttachmentDissociationReliability of Central Vein Sign Imaging With 3T FLAIR* in a Multicenter Study
Martin M, Cao Q, Luskin E, Renner B, Daboul L, O'Donnell C, Rodrigues P, Derbyshire J, Azevedo C, Bar‐Or A, Caverzasi E, Calabresi P, Cree B, Freeman L, Henry R, Longbrake E, Oh J, Papinutto N, Pelletier D, Prchkovska V, Ramos M, Samudralwar R, Schindler M, Sotirchos E, Sicotte N, Solomon A, Reich D, Ontaneda D, Shinohara R, Sati P. Reliability of Central Vein Sign Imaging With 3T FLAIR* in a Multicenter Study. Journal Of Neuroimaging 2025, 35: e70011. PMID: 39838609, DOI: 10.1111/jon.70011.Peer-Reviewed Original ResearchConceptsCentral vein signMulticenter studyMultiple sclerosisT2-weighted fluid-attenuated inversion recoveryClinical settingMRI vendorsFluid-attenuated inversion recoveryDiagnosis of MSPost-GdContrast-to-noise ratioGd-based contrast agentsNo significant differenceT2*-weightedImaging sitesDiagnostic imaging biomarkersImaging biomarkersInversion recoverySignificant differenceMRIFLAIRContrast agentsCerebrospinal Fluid Biomarkers and Cognition in Alzheimer Disease and Frontotemporal Dementia in a Memory Clinic Setting
Cayir S, Sadabad F, Mecca A, Matuskey D, Fesharaki-Zadeh A. Cerebrospinal Fluid Biomarkers and Cognition in Alzheimer Disease and Frontotemporal Dementia in a Memory Clinic Setting. Alzheimer Disease & Associated Disorders 2025, 39: 22-27. DOI: 10.1097/wad.0000000000000656.Peer-Reviewed Original ResearchMoCA scoresMemory clinic settingHospital memory clinicCognitive performanceMontreal Cognitive AssessmentFrontotemporal dementiaAlzheimer's diseaseCognitive test scoresP-tauMemory clinicElectronic records of patientsRetrospective cohort studyT-tauCohort studyCognitive AssessmentElectronic recordsMoCACerebrospinal fluidRecords of patientsIndex scoreTau-related pathologyClinical settingDementiaConcentrations of T-tauScores
2024
MDMA and MDMA-Assisted Therapy
Wolfgang A, Fonzo G, Gray J, Krystal J, Grzenda A, Widge A, Kraguljac N, McDonald W, Rodriguez C, Nemeroff C. MDMA and MDMA-Assisted Therapy. American Journal Of Psychiatry 2024, 182: 79-103. PMID: 39741438, DOI: 10.1176/appi.ajp.20230681.Peer-Reviewed Original ResearchConceptsMDMA-assisted therapyPosttraumatic stress disorderControlled clinical settingRecreational useMDMA administrationNeurobiological mechanismsStress disorderEgo functionsSelf-compassionMDMAEfficacious treatmentPreliminary evidenceHeightened trustTherapeutic settingNonclinical settingsDiagnostic criteriaFood and Drug AdministrationBreakthrough therapiesClinical settingNonmedical settingsConsiderable bodyPsychotherapyPsychedelicsLong-term follow-upDrug AdministrationMeasurement and Prevalence of Aggression
Iennaco J, Molle E, Lauvrud C, Palmstierna T, Nijman H, Almvik R. Measurement and Prevalence of Aggression. 2024, 93-123. DOI: 10.1007/978-3-031-61224-4_5.Peer-Reviewed Original ResearchQuality of carePatient safetyActivity programmeHealthcare workplaceHealthcare settingsPatient carePsychiatric settingsOverview of scalesImpact patientsTherapeutic relationshipClinical environmentCoercive interventionsPrevalence of aggressionClinical settingCareHealthcareSeverity of violenceHigher ratesPrevalenceViolenceCaregiversSetsPatientsComplex issuesInterventionComparing the Accuracy and Reliability of ABC/2 and Planimetry for Vestibular Schwannoma Volume Assessment
Singh K, Abdou H, Panth N, Chiang V, Buono F, Schwartz N, Mahajan A. Comparing the Accuracy and Reliability of ABC/2 and Planimetry for Vestibular Schwannoma Volume Assessment. Otology & Neurotology 2024, 46: 196-200. PMID: 39792983, DOI: 10.1097/mao.0000000000004392.Peer-Reviewed Original ResearchConceptsTumor volume assessmentABC/2 methodVestibular schwannomaVolume assessmentPlanimetry methodTumor volumeTumor volume changesFollow-up scansOverestimate tumor volumePatients' quality of lifeTumor sizeRetrospective reviewIntracranial tumorsImprove clinical decision makingSubgroup analysisVolumetric assessmentTumorClinical decision makingQuality of lifePatients' qualityPatientsClinical settingPlanimetryImaging techniquesPositive correlationMulti-omics approaches to decipher the interactions of nanoparticles and biological systems
Wang Y, Xiao Z, Wang Z, Lee D, Ma Y, Wilhelm S, Wang H, Kim B, Jiang W. Multi-omics approaches to decipher the interactions of nanoparticles and biological systems. Nature Reviews Bioengineering 2024, 1-16. DOI: 10.1038/s44222-024-00264-4.Peer-Reviewed Original ResearchMulti-omics approachNano-bio interactionsMulti-omicsMulti-omics pipelineMulti-omics dataSubcellular levelHigh-throughput mannerApplication of transcriptomicsNanoparticles in vivoMetabolomics technologyTreatment strategiesNanoparticle uptakeBiological systemsOptimized nanoparticlesEngineered nanoparticlesBiological informationImplementation of nanoparticlesClinical settingInteraction of nanoparticlesCell typesNano-bio interfaceEpigenomeTranscriptomeMetabolomicsBioinformaticsCultivating participatory processes in self‐harm app development: A case‐study and working methodology
Babbage C, Lockwood J, Roberts L, Mendes J, Greenhalgh C, Willingham L, Wokomah E, Woodcock R, Slovak P, Townsend E, Townsend E, Hollis C, Gregory J, Vallejos E, Woodcock R, Fonagy P, Arseneault L, Doherty S, Willingham L, Creswell C, Lloyd E, De Alcantara Mendes J, Holter C, Jirotka M, Patalay P, Kelly Y, Kandola A, Sonuga‐Barke E, Livingstone S, Kostryka‐Allchorne K, Stoilova M, O'Connor R, Auer D, Lee S, Jawahar N, Etherson M, Greenhalgh C, Sayal K, Warren J, Wanniarachchi V, Stallard P, Hall C, Lucassen M, Merry S, Stasiak K, Babbage C, Parker A, Griffiths H, Roberts L, Slovak P, Williams A, Lockwood J. Cultivating participatory processes in self‐harm app development: A case‐study and working methodology. JCPP Advances 2024, 4: e12295. PMID: 39734924, PMCID: PMC11669782, DOI: 10.1002/jcv2.12295.Peer-Reviewed Original ResearchSelf-harmManagement of self-harmSuicide related behaviorsAdolescent self-harmMental health developmentDigital mental healthMental healthYoung peopleRelated behaviorsPatient involvementFace-to-faceClinical supportHealth developmentCodesign processParticipatory practicesParticipatory aspectsDecision-makingClinical settingClinical toolApplication of digital tools and artificial intelligence in the Myasthenia Gravis Core Examination
Garbey M, Lesport Q, Girma H, Öztosun G, Abu-Rub M, Guidon A, Juel V, Nowak R, Soliven B, Aban I, Kaminski H. Application of digital tools and artificial intelligence in the Myasthenia Gravis Core Examination. Frontiers In Neurology 2024, 15: 1474884. PMID: 39697445, PMCID: PMC11652356, DOI: 10.3389/fneur.2024.1474884.Peer-Reviewed Original ResearchNatural language processingMyasthenia gravisArtificial intelligenceArtificial intelligence methodsSeries of algorithmsComputer visionSignal processing methodsExamination of patientsConventional clinical settingsLanguage processingIntelligence methodsNon-physician healthcare providersVideoControl subjectsClinical trialsPatientsRespiratory metricsMyastheniaBreath countClinical settingAlgorithmBody motionVideos of patientsTelemedicine evaluationIntelligenceArtificial Intelligence, Clinical Decision Support Algorithms, Mathematical Models, Calculators Applications in Infertility: Systematic Review and Hands-On Digital Applications
Bulletti C, Franasiak J, Busnelli A, Sciorio R, Berrettini M, Aghajanova L, Bulletti F, Ata B. Artificial Intelligence, Clinical Decision Support Algorithms, Mathematical Models, Calculators Applications in Infertility: Systematic Review and Hands-On Digital Applications. Mayo Clinic Proceedings Digital Health 2024, 2: 518-532. DOI: 10.1016/j.mcpdig.2024.08.007.Peer-Reviewed Original ResearchClinical decision support algorithmsAssisted reproductive technologyDecision support algorithmEvidence-based guidanceSupport algorithmClinical managementDecision aidImprove in vitro fertilization outcomesSystematic reviewInclusion criteriaRelevant articlesLiterature searchPatient counselingClinical settingRetrospective studyART cyclesAssisted reproductive technology practicesClinical trialsEmbryo assessmentFertility outcomesLack of standardizationReproductive technologyPracticeArtificial intelligenceCounselingPATCH (Preferred Attachment Strategy for Optimal Electrocardiograms)-1 Study
Becker R, Harnett B, Wayne D, Mardis R, Meganathan K, Steen D. PATCH (Preferred Attachment Strategy for Optimal Electrocardiograms)-1 Study. Clinical Research In Cardiology 2024, 114: 497-506. PMID: 39527276, DOI: 10.1007/s00392-024-02572-6.Peer-Reviewed Original ResearchStable cardiovascular diseaseAmbulatory clinic visitsAmbulatory clinic settingCardiovascular diseaseS-ECGClinical research coordinatorsClinical indicationsClinic visitsResearch coordinatorsValvular heart diseaseCoronary artery diseaseMedical practiceParticipantsEssential hypertensionClinical settingLead placementAtrial fibrillationHeart diseaseHeart failureTreatment decisionsArtery diseaseST-TElectrocardiographyBaselineHeart rhythmWorkplace-based assessment to support entrustment decision-making: four sources of information
ten Cate O, Jonker G, Park Y, Holmboe E, Burch V. Workplace-based assessment to support entrustment decision-making: four sources of information. 2024, 197-211. DOI: 10.5334/bdc.q.Peer-Reviewed Original ResearchWorkplace-based assessmentPatient carePatient care activitiesAuthentic clinical settingsSource of informationOne-on-one discussionsDocumentation of informationProgram of assessmentClinical competency committeeCare activitiesAssessment of traineesMultisource feedbackTrainee readinessCompetency committeeLongitudinal observationsDecision-makingEntrustment decision-makingTraineesProbe knowledgeClinical settingCareFocused feedbackData pointsAssessmentInformationBrain-phenotype predictions of language and executive function can survive across diverse real-world data: Dataset shifts in developmental populations
Adkinson B, Rosenblatt M, Dadashkarimi J, Tejavibulya L, Jiang R, Noble S, Scheinost D. Brain-phenotype predictions of language and executive function can survive across diverse real-world data: Dataset shifts in developmental populations. Developmental Cognitive Neuroscience 2024, 70: 101464. PMID: 39447452, PMCID: PMC11538622, DOI: 10.1016/j.dcn.2024.101464.Peer-Reviewed Original ResearchBrain-phenotype associationsConnectome-based predictive modelingBrain-behavior associationsPrediction of languagePhiladelphia Neurodevelopmental CohortHealthy Brain NetworkClinical symptom burdenFMRI taskHuman Connectome ProjectExecutive functionBehavioral measuresDevelopmental populationsNeurodevelopmental CohortBrain networksDevelopmental sampleConnectome ProjectResearch settingsGeneralizabilitySymptom burdenExternal validationFMRIClinical settingAssociationEthnic minority representationTaskMixed-field ABO front typing as an early sign of disease recurrence in ABO-matched stem cell transplantation
Yurtsever N, Lee E, Pinatti L, Shah B, Tormey C, Siddon A. Mixed-field ABO front typing as an early sign of disease recurrence in ABO-matched stem cell transplantation. Immunohematology 2024, 40: 89-92. PMID: 39373301, PMCID: PMC11700658, DOI: 10.2478/immunohematology-2024-013.Peer-Reviewed Original ResearchConceptsStem cell transplantationCell transplantationDisease recurrenceMyeloid neoplasmsChimerism testingAllogeneic stem cell transplantationSigns of disease recurrenceIndicator of disease recurrenceDonor-recipient pairsABO antigen expressionGraft statusAntigen expressionFemale patientsPost-transplantationAllograft statusTransplantationABO typeRecurrenceClinical settingEarly signsNeoplasmsChimerismEarly indicatorABOEngraftmentDirect analysis in real time mass spectrometry (DART-MS/MS) for rapid urine opioid detection in a clinical setting
Choucair I, Shang E, Tran M, Cassella-McLane G, El-Khoury J. Direct analysis in real time mass spectrometry (DART-MS/MS) for rapid urine opioid detection in a clinical setting. Clinica Chimica Acta 2024, 564: 119939. PMID: 39197698, DOI: 10.1016/j.cca.2024.119939.Peer-Reviewed Original ResearchDART-MS/MSMass spectrometryReal time mass spectrometryTime mass spectrometrySample preparationLC-MS/MSEfficient sample preparationTandem mass spectrometryDirect analysisLiquid chromatography-tandem mass spectrometryChromatography-tandem mass spectrometryAnalytical measurement rangeVortex timeSpectrometryOpioid drugsTurnaround timeUrine samplesOpioidClinical settingDrug testingUrineDefinitive testsNorfentanylDrugPreparationNon-invasive preimplantation genetic testing for aneuploidy: is the promise real?
Volovsky M, Scott R, Seli E. Non-invasive preimplantation genetic testing for aneuploidy: is the promise real? Human Reproduction 2024, 39: 1899-1908. PMID: 38970367, DOI: 10.1093/humrep/deae151.Peer-Reviewed Original ResearchNon-invasive PGT-APGT-APreimplantation genetic testingIntegration of next-generation sequencingGenetic testingGenetic testing platformsNon-invasive preimplantation genetic testingNext-generation sequencingRisk of pregnancy lossAneuploidy screening methodsEmbryo culture mediumAmplification failureSegmental aneuploidyPregnancy lossCulture mediumClinical reliabilityAneuploidyDiagnostic precisionClinical settingDiagnostic inaccuracyEmbryo viabilityClinical adoptionEmbryosScreening methodDNAThe European psychiatric association (EPA) – early career psychiatrists committee survey on trainees’ and early-career psychiatrists’ attitudes towards therapeutic drug monitoring (TDM) use and utility during antipsychotic treatment
Schoretsanitis G, Correll C, Agorastos A, Sanchez A, Erzin G, Grigoras R, Benussi M, Gondek T, Guloksuz S, Højlund M, Jerotic S, Kilic O, Metaj E, Sidhu D, Skandali N, Skuhareuski A, Tveito M, Wolthusen R, Communication and Publications E, Chumakov E, de Filippis R. The European psychiatric association (EPA) – early career psychiatrists committee survey on trainees’ and early-career psychiatrists’ attitudes towards therapeutic drug monitoring (TDM) use and utility during antipsychotic treatment. The World Journal Of Biological Psychiatry 2024, 25: 342-351. PMID: 38905131, DOI: 10.1080/15622975.2024.2367138.Peer-Reviewed Original ResearchConceptsEuropean Psychiatric AssociationAntipsychotic treatmentPsychiatrists' attitudesTherapeutic drug monitoringEarly-career psychiatristsExploratory factor analysisBenefit of therapeutic drug monitoringPsychiatric AssociationAntipsychoticsNegative expectationsAssociated with frequencyTDM useDrug monitoringTherapeutic drug monitoring useFactor analysisBeliefs of patientsHigh-income countriesLow-/middle-income countriesResponse varianceClinical benefitClozapineOutpatient settingLinear regression analysisClinical settingPsychiatrists
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