2025
Post-vasectomy semen analysis: what is the best protocol?
Cahill E, Rabil M, Rotker K, Honig S. Post-vasectomy semen analysis: what is the best protocol? International Journal Of Impotence Research 2025, 1-5. PMID: 40155486, DOI: 10.1038/s41443-025-01052-3.Peer-Reviewed Original ResearchPost-vasectomy semen analysisAmerican Urological AssociationNon-motile spermSemen analysisPatient complianceAmerican Urological Association guidelinesFactors associated with complianceInitial clearance rateUrological AssociationPermanent sterilizationPatientsClearance ratePatient embarrassmentPatient preferencesVasectomyAzoospermiaAt-home testingClearanceIncrease complianceAlternative optionEffective formComplianceContraceptionCorrecting SUVR bias by accounting for radiotracer clearance in tissue: A validation study with [18F]FE-PE2I PET in cross-sectional, test-retest and longitudinal cohorts.
Oh M, Honhar P, Carson R, Hillmer A, Varrone A. Correcting SUVR bias by accounting for radiotracer clearance in tissue: A validation study with [18F]FE-PE2I PET in cross-sectional, test-retest and longitudinal cohorts. Cerebrovascular And Brain Metabolism Reviews 2025, 271678x251322407. PMID: 39981611, PMCID: PMC11846093, DOI: 10.1177/0271678x251322407.Peer-Reviewed Original Research
2023
Improving SUVR quantification by correcting for radiotracer clearance in tissue
Honhar P, Matuskey D, Carson R, Hillmer A. Improving SUVR quantification by correcting for radiotracer clearance in tissue. Cerebrovascular And Brain Metabolism Reviews 2023, 44: 296-309. PMID: 37589538, PMCID: PMC10993874, DOI: 10.1177/0271678x231196804.Peer-Reviewed Original Research
2022
Quantifying the impact of immune history and variant on SARS-CoV-2 viral kinetics and infection rebound: A retrospective cohort study
Hay J, Kissler S, Fauver J, Mack C, Tai C, Samant R, Connolly S, Anderson D, Khullar G, MacKay M, Patel M, Kelly S, Manhertz A, Eiter I, Salgado D, Baker T, Howard B, Dudley J, Mason C, Nair M, Huang Y, DiFiori J, Ho D, Grubaugh N, Grad Y. Quantifying the impact of immune history and variant on SARS-CoV-2 viral kinetics and infection rebound: A retrospective cohort study. ELife 2022, 11: e81849. PMID: 36383192, PMCID: PMC9711520, DOI: 10.7554/elife.81849.Peer-Reviewed Original ResearchConceptsViral kineticsSARS-CoV-2 strainsAntibody titersViral reboundVaccination statusLonger clearance timeLower peak viral loadRetrospective cohort studyClearance timePeak viral loadSARS-CoV-2 variantsHigh antibody titersEffective immune responseRT-qPCR testingBooster vaccinationCohort studyEffect of ageViral loadHealth cohortSymptom statusImmune historyImmune responseInfection historyClearance rateInfectionDual-targeted enzyme-sensitive hyaluronic acid nanogels loading paclitaxel for the therapy of breast cancer
Gao D, Asghar S, Ye J, Zhang M, Hu R, Wang Y, Huang L, Yuan C, Chen Z, Xiao Y. Dual-targeted enzyme-sensitive hyaluronic acid nanogels loading paclitaxel for the therapy of breast cancer. Carbohydrate Polymers 2022, 294: 119785. PMID: 35868795, DOI: 10.1016/j.carbpol.2022.119785.Peer-Reviewed Original ResearchConceptsBreast cancerHyaluronic acid nanogelsTumor-bearing BALB/c miceTherapy of breast cancerTreatment of breast cancerTargeting breast cancerBreast cancer cellsRat pharmacokinetic profilesIn vivo studiesTherapeutic efficacyBALB/c miceEntrapment efficiencyPharmacokinetic profileCancer cellsClearance rateCD44 receptorControl groupCancerPaclitaxelDrug loadingHigher cytotoxicityReceptorsCD44DrugCells
2016
Rates and determinants of incidence and clearance of cervical HPV genotypes among HIV-seropositive women in Pune, India
Mane A, Sahasrabuddhe VV, Nirmalkar A, Risbud AR, Sahay S, Bhosale RA, Vermund SH, Mehendale SM. Rates and determinants of incidence and clearance of cervical HPV genotypes among HIV-seropositive women in Pune, India. Journal Of Clinical Virology 2016, 88: 26-32. PMID: 28152432, PMCID: PMC5441893, DOI: 10.1016/j.jcv.2016.10.013.Peer-Reviewed Original ResearchConceptsHIV-seropositive womenCervical HPV genotypesHPV genotypesClearance rateHPV infectionAge-related hormonal changesRoche Linear Array HPVAlpha-7 speciesAntiretroviral therapy statusCarcinogenic HPV genotypesCervical HPV infectionGenotype-specific prevalenceLinear Array HPVAge of participantsCD4 countHPV incidenceImmunologic factorsDeterminants of incidenceHPV typesTherapy statusProspective studyCervical samplesIncidence rateHormonal changesEtiologic studies
2015
Mapping 15O Production Rate for Proton Therapy Verification
Grogg K, Alpert N, Zhu X, Min C, Testa M, Winey B, Normandin M, Shih H, Paganetti H, Bortfeld T, Fakhri G. Mapping 15O Production Rate for Proton Therapy Verification. International Journal Of Radiation Oncology • Biology • Physics 2015, 92: 453-459. PMID: 25817530, PMCID: PMC4431894, DOI: 10.1016/j.ijrobp.2015.01.023.Peer-Reviewed Original ResearchConceptsDecay constantProton treatment planningMonte Carlo predictionsProton therapyPhantom materialTreatment deliveryPhantomThigh activityPositron emission tomographyProduction rateDynamic PET measurementsTreatment planningRabbit thigh muscleClearance rateProtonIsotopesChanges due to therapyRadionuclide speciesOxygen-15ConstantDecayImaging targetsMontePositronEffects of perfusion
2012
Genotype-specific incidence and clearance rates of human papilloma virus (HPV) infection in HIV-infected women from Pune, India
Mane A, Nirmalkar A, Risbud A, Vermund S, Mehendale S, Sahasrabuddhe V. Genotype-specific incidence and clearance rates of human papilloma virus (HPV) infection in HIV-infected women from Pune, India. BMC Infectious Diseases 2012, 12: o2. PMCID: PMC3344689, DOI: 10.1186/1471-2334-12-s1-o2.Peer-Reviewed Original Research
2011
Comparative Effectiveness of Aminoglycosides, Polymyxin B, and Tigecycline for Clearance of Carbapenem-Resistant Klebsiella pneumoniae from Urine
Satlin MJ, Kubin CJ, Blumenthal JS, Cohen AB, Furuya EY, Wilson SJ, Jenkins SG, Calfee DP. Comparative Effectiveness of Aminoglycosides, Polymyxin B, and Tigecycline for Clearance of Carbapenem-Resistant Klebsiella pneumoniae from Urine. Antimicrobial Agents And Chemotherapy 2011, 55: 5893-5899. PMID: 21968368, PMCID: PMC3232750, DOI: 10.1128/aac.00387-11.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAminoglycosidesAnti-Bacterial AgentsCarbapenemsCohort StudiesDrug Resistance, BacterialFemaleHumansKlebsiella InfectionsKlebsiella pneumoniaeMaleMicrobial Sensitivity TestsMiddle AgedMinocyclinePolymyxin BRetrospective StudiesTigecyclineTreatment OutcomeUrinary Tract InfectionsUrineYoung AdultConceptsCarbapenem-resistant Klebsiella pneumoniaePolymyxin BCRKP bacteriuriaMicrobiologic clearanceUntreated cohortHealth care-associated urinary tract infectionsClearance rateKlebsiella pneumoniaeRetrospective cohort studyUrinary tract infectionNew York Presbyterian HospitalCohort studyTract infectionsUrine cultureAntimicrobial therapyAppropriate followCommon causeActive agentsMultiple active agentsTigecyclineComparative effectivenessMultivariate analysisCohortGram-negative activityAminoglycosides
2007
Pharmacokinetics of Antimony in Children Treated for Leishmaniasis with Meglumine Antimoniate
Cruz A, Rainey PM, Herwaldt BL, Stagni G, Palacios R, Trujillo R, Saravia NG. Pharmacokinetics of Antimony in Children Treated for Leishmaniasis with Meglumine Antimoniate. The Journal Of Infectious Diseases 2007, 195: 602-608. PMID: 17230422, DOI: 10.1086/510860.Peer-Reviewed Original ResearchConceptsPharmacokinetics of antimonyMeglumine antimoniateDrug exposureIntramuscular meglumine antimoniateWeight-adjusted clearancePeak concentrationPotential clinical relevanceTime-concentration curveLower peak concentrationsAntimonial therapyPharmacokinetic differencesCutaneous leishmaniasisClinical relevanceChildren 3Day 20Clearance rateAntimoniateLeishmaniasisAdultsChildrenSecond groupFirst groupPharmacokineticsDaysExposure
1995
Oral vinorelbine (Navelbine) in the treatment of advanced breast cancer.
Winer EP, Chu L, Spicer DV. Oral vinorelbine (Navelbine) in the treatment of advanced breast cancer. Seminars In Oncology 1995, 22: 72-8; discussion 78-9. PMID: 7740337.Peer-Reviewed Original ResearchConceptsAdvanced breast cancerOral vinorelbineBreast cancerIntravenous administrationResponse rateMulticenter phase II trialAdvanced breast cancer patientsPhase II trialHigh first-pass effectBreast cancer patientsFirst-pass effectPharmacokinetics of vinorelbineII trialCancer patientsClinical investigationVinorelbineHigh clearance rateSoft gelatin capsulesClearance ratePatientsCancerPharmacokinetic studyLow bioavailabilityAdministrationGelatin capsules
1985
Effects of timed melatonin injections on reproduction in pinealectomized Peromyscus leucopus
Hall E, Makoul G, Lynch G, Anderson G. Effects of timed melatonin injections on reproduction in pinealectomized Peromyscus leucopus. General And Comparative Endocrinology 1985, 58: 407-414. PMID: 4007479, DOI: 10.1016/0016-6480(85)90113-3.Peer-Reviewed Original ResearchConceptsSham-operated miceReproductive tract weightMelatonin injectionsMicrograms melatoninSham-operated animalsSurgical treatmentDaily injectionsPinealectomized miceSurgeryClearance rateMelatonin concentrationsMicePlasma melatoninTime pointsWeeksMelatoninInjectionWhite-footed miceHigh-performance liquid chromatographyHrPinealectomizedLong-day photoperiodLiquid chromatographyGroupRadioimmunoassayClearance of Large Amounts of Natural Surfactants and Liposomes of Dipalmitoylphosphatidylcholine from the Lungs of Rabbits
Oguchi K, Ikegami M, Jacobs H, Jobe A. Clearance of Large Amounts of Natural Surfactants and Liposomes of Dipalmitoylphosphatidylcholine from the Lungs of Rabbits. Experimental Lung Research 1985, 9: 221-235. PMID: 3841050, DOI: 10.3109/01902148509057525.Peer-Reviewed Original ResearchConceptsTotal lungLung tissueRabbit surfactantAlveolar washSheep surfactantAlveolar surfactant pool sizeEndogenous surfactant metabolismEndogenous surfactant poolsSurfactant pool sizeDifferent surfactant preparationsNatural rabbit surfactantLungs of rabbitsNatural sheep surfactantIntratracheal administrationIntratracheal injectionLung phosphatidylcholineSurfactant poolQuantity of phosphatidylcholineSurfactant metabolismLungClearance rateSurfactant phosphatidylcholineTotal phosphatidylcholineMetabolic responseSurfactant preparations
1974
CLEARANCE RATE OF EXOGENOUS 3H‐THYMIDINE FROM THE PLASMA OF PREGNANT RHESUS MONKEYS
Nowakowski R, Rakic P. CLEARANCE RATE OF EXOGENOUS 3H‐THYMIDINE FROM THE PLASMA OF PREGNANT RHESUS MONKEYS. Cell Proliferation 1974, 7: 189-194. PMID: 4205927, DOI: 10.1111/j.1365-2184.1974.tb00411.x.Peer-Reviewed Original Research
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