2024
Understanding the Added Value of High-Resolution CT Beyond Chest X-Ray in Determining Extent of Physiologic Impairment
Benn B, Lippitt W, Cortopassi I, Balasubramani G, Barbosa E, Drake W, Herzog E, Gibson K, Chen E, Koth L, Fuhrman C, Lynch D, Kaminski N, Wisniewski S, Carlson N, Maier L. Understanding the Added Value of High-Resolution CT Beyond Chest X-Ray in Determining Extent of Physiologic Impairment. CHEST Journal 2024, 166: 1093-1107. PMID: 38830401, PMCID: PMC11560486, DOI: 10.1016/j.chest.2024.04.031.Peer-Reviewed Original ResearchScadding stageCT featuresLung functionChest radiologistsCT scanAlpha-1 anti-trypsin deficiencyChest computed tomographyChest CT scanChest X-rayIncreasing clinical useCompare demographic featuresAssociated with FEV1Visual scoring systemSarcoidosis stagePulmonary sarcoidosisChest CTCT findingsAssociated with lung functionCT assessmentComputed tomographySarcoidosisClinical useRadiological measurementsCT measurementsScoring system
2023
Spatial Transcriptomics Resolve an Emphysema-specific Lymphoid Follicle B Cell Signature in COPD.
Rojas-Quintero J, Ochsner S, New F, Divakar P, Yang C, Wu T, Robinson J, Shimoga Chandrashekar D, Banovich N, Rosas I, Sauler M, Kheradmand F, Gaggar A, Margaroli C, San Jose Estepar R, McKenna N, Polverino F. Spatial Transcriptomics Resolve an Emphysema-specific Lymphoid Follicle B Cell Signature in COPD. American Journal Of Respiratory And Critical Care Medicine 2023 PMID: 38064378, DOI: 10.1164/rccm.202303-0507oc.Peer-Reviewed Original ResearchChronic obstructive pulmonary diseaseB cell activationLymphoid folliclesCOPD patientsGOLD 1Cell activationChronic B-cell activationObstructive pulmonary diseaseB cell signaturesAnti-inflammatory profileChest CT scanDegree of emphysemaB cell marker genesB cell maturationSevere emphysemaPulmonary diseaseEmphysema measurementsLung sectionsAntigen presentationGOLD 3Centrilobular emphysemaCT scanImmune componentsEmphysema pathogenesisEmphysemaBrief Report: Increasing Prevalence of Ground-Glass Nodules and Semisolid Lung Lesions on Outpatient Chest Computed Tomography Scans
Woodard G, Udelsman B, Prince S, Blasberg J, Dhanasopon A, Gange C, Traube L, Mase V, Boffa D, Detterbeck F, Bader A. Brief Report: Increasing Prevalence of Ground-Glass Nodules and Semisolid Lung Lesions on Outpatient Chest Computed Tomography Scans. JTO Clinical And Research Reports 2023, 4: 100583. PMID: 38074773, PMCID: PMC10709040, DOI: 10.1016/j.jtocrr.2023.100583.Peer-Reviewed Original ResearchGround-glass nodulesChest CT scanCT scanLung lesionsHealth systemLarge academic health systemAcademic health systemCross-sectional imagingRadiographic findingsPhysician consultationChest CTDatabase reviewTomography scanRadiographic lesionsAge groupsLesionsStudy periodLung nodulesOutpatient CTRadiology reportsAdult chestCTScansChestNodules
2022
Using Routine Chest Computed Tomography to Diagnose Pulmonary Embolism
Chan J, Ho B, Ye K, Haramati L, Jain V. Using Routine Chest Computed Tomography to Diagnose Pulmonary Embolism. Journal Of Computer Assisted Tomography 2022, 46: 888-893. PMID: 36399535, DOI: 10.1097/rct.0000000000001372.Peer-Reviewed Original ResearchConceptsPulmonary embolismPulmonary artery enhancementContrast-enhanced chest CT scansHU thresholdContrast-enhanced chest CTAbsence of PEUnsuspected pulmonary embolismContrast-enhanced chestHounsfield unitsChest CT scanLogistic regression analysisPeripheral enhancementPulmonary vasculatureChest CTFemale sexRoutine chestContrast amountCT scanPulmonary enhancementTotal casesOlder ageEmbolismRegression analysisChestDescriptive statistics
2019
Detection of TGF-β in pleural effusions for diagnosis and prognostic stratification of malignant pleural mesothelioma
Stockhammer P, Ploenes T, Theegarten D, Schuler M, Maier S, Aigner C, Hegedus B. Detection of TGF-β in pleural effusions for diagnosis and prognostic stratification of malignant pleural mesothelioma. Lung Cancer 2019, 139: 124-132. PMID: 31778960, DOI: 10.1016/j.lungcan.2019.11.013.Peer-Reviewed Original ResearchConceptsMalignant pleural mesotheliomaNon-malignant pleural diseasePleural effusionMPM patientsPleural mesotheliomaPrognostic stratificationNon-epithelioid malignant pleural mesotheliomaStage IV lung cancerEpithelioid malignant pleural mesotheliomaInferior overall survivalTGF-β levelsLevels of TGFLung cancer patientsChest CT scanOverall survivalSMRP levelsClinicopathological characteristicsDismal prognosisPleural diseaseTumor loadAggressive malignancyDisease stageCancer patientsLung cancerPrimary diagnosis
2016
Unusual presentation of disseminated Nocardia abscessus infection in a patient with AIDS
Sherbuk J, Saly D, Barakat L, Ogbuagu O. Unusual presentation of disseminated Nocardia abscessus infection in a patient with AIDS. BMJ Case Reports 2016, 2016: bcr2016215649. PMID: 27440848, PMCID: PMC4964189, DOI: 10.1136/bcr-2016-215649.Peer-Reviewed Case Reports and Technical NotesConceptsAbscessus infectionCentral nervous system lesionsNodular pulmonary infiltratesExcellent therapeutic responseRing-enhancing lesionsNervous system lesionsCombination antimicrobial therapyChest CT scanPulmonary infiltratesSubacute headacheChronic coughFecal incontinenceGeneralised weaknessPathological examinationSystem lesionsPurulent materialSubcutaneous nodulesUnusual presentationTherapeutic responseAntimicrobial therapySpinal cordCT scanSubcutaneous lesionsN. abscessusLesions
2015
Thoracoscopic Resection of a Bronchogenic Cyst in a Premature Infant
Rosati S, Maarouf R, Nishitani M, Oiticica C, Lanning D. Thoracoscopic Resection of a Bronchogenic Cyst in a Premature Infant. Journal Of Laparoendoscopic & Advanced Surgical Techniques 2015, 25 DOI: 10.1089/vor.2015.0282.Peer-Reviewed Original ResearchBronchogenic cystPremature infantsThoracoscopic approachMediastinal cystsNeonatal ICUCongenital pulmonary airway malformationPostoperative chest X-rayNo competing financial interestsIntercostal spaceBenign congenital anomalyCongenital mediastinal cystsGentle blunt dissectionPosterior mediastinal cystMinimal blood lossEarly surgical interventionPostoperative day 2Shorter postoperative courseChest CT scanForegut duplication cystCompression of local structuresLeft main stem bronchusPosterior axillary lineSignificant air trappingChest X-rayMain stem bronchusRobot-Assisted Resection of a Large Posterior Mediastinal Mass
Parrish D, Rosati S, Oiticica C, Lange P, Lanning D. Robot-Assisted Resection of a Large Posterior Mediastinal Mass. Journal Of Laparoendoscopic & Advanced Surgical Techniques 2015, 25 DOI: 10.1089/vor.2014.0245.Peer-Reviewed Original ResearchRobot-assisted resectionRobotic trocarsChest tubeHorner's syndromeAxillary lineLeft chestArticulating instrumentsNo competing financial interestsRobot-assisted thoracic surgeryLeft anterior axillary lineNeural crest cell originLeft arm numbnessLeft chest massPostoperative day 1Postoperative day 2Chest CT scanPosterior axillary lineAnterior axillary lineSymptoms of Horner's syndromeChest X-rayShortness of breathLeft upper chestFinal pathologyEndocatch bagChest painComponents Necessary for High-Quality Lung Cancer Screening American College of Chest Physicians and American Thoracic Society Policy Statement
Mazzone P, Powell CA, Arenberg D, Bach P, Detterbeck F, Gould MK, Jaklitsch MT, Jett J, Naidich D, Vachani A, Wiener RS, Silvestri G. Components Necessary for High-Quality Lung Cancer Screening American College of Chest Physicians and American Thoracic Society Policy Statement. CHEST Journal 2015, 147: 295-303. PMID: 25356819, PMCID: PMC4502754, DOI: 10.1378/chest.14-2500.Peer-Reviewed Original ResearchConceptsLung cancer screening programsCancer screening programsLung cancer screeningAmerican Thoracic SocietyCancer screeningScreening programChest PhysiciansAmerican CollegeHigh-quality lung cancer screening programThoracic Oncology NetworkEvidence-based reviewLow-dose chest CT scansChest CT scanAmerican Cancer SocietyLung cancerComponents of screeningEssential program componentsThoracic SocietyOncology NetworkCancer SocietyCT scanProgram componentsPreventive oncologyAmerican SocietyScreening facility
2014
Management of Pneumothoraces Detected on Chest Computed Tomography: Can Anatomical Location Identify Patients Who Can Be Managed Expectantly?
Agbo C, Hempel D, Studer M, Gulati K, Oliva I, Goldflam K, Ledbetter S, Platz E. Management of Pneumothoraces Detected on Chest Computed Tomography: Can Anatomical Location Identify Patients Who Can Be Managed Expectantly? Journal Of Emergency Medicine 2014, 46: 605-611. PMID: 24508116, DOI: 10.1016/j.jemermed.2013.11.079.Peer-Reviewed Original ResearchConceptsChest tube thoracotomyChest CT scanCT scanComputed tomographyEmergency departmentAnatomical distributionLevel I trauma centerInitial hemodynamic parametersManagement of pneumothoracesTrauma ultrasound examinationI trauma centerMajority of patientsManagement of pneumothoraxSize of pneumothoraxChest Computed TomographyDistinct anatomical distributionChest zonesTube thoracotomyStable patientsMechanical ventilationMedian timeRetrospective reviewTrauma centerChest tubeMedical records
2005
Single Institution Experience with Inferior Vena Cava Filters.
Bhalla N, Bulgaru A, Church L, Kapur D, Lustberg H, Slater D, Dhami M. Single Institution Experience with Inferior Vena Cava Filters. Blood 2005, 106: 914. DOI: 10.1182/blood.v106.11.914.914.Peer-Reviewed Original ResearchDeep venous thrombosisRetrievable IVC filtersRecurrent deep venous thrombosisInferior vena cava filterSymptomatic pulmonary embolismPulmonary embolismPermanent IVC filtersIVC filtersVena cava filtersPermanent filtersClot burdenVenous thromboembolismCava filtersSymptomatic deep venous thrombosisTransient low-grade feverPoor pulmonary reserveRetrieval of filtersLow-grade feverRecurrent venous thromboembolismIncidence of complicationsIVC filter insertionLong-term anticoagulationSingle institution experienceAdverse clinical consequencesChest CT scanIntrathoracic Lymphadenopathy in Hospitalized Patients With Pneumococcal Pneumonia
Stein D, Haramati L, Spindola-Franco H, Friedman J, Klapper P. Intrathoracic Lymphadenopathy in Hospitalized Patients With Pneumococcal Pneumonia. CHEST Journal 2005, 127: 1271-1275. DOI: 10.1016/s0012-3692(15)34476-7.Peer-Reviewed Original ResearchConceptsPrevalence of lymphadenopathyCharacteristics of pneumoniaPneumococcal pneumoniaCT scanIntrathoracic lymphadenopathyHospitalized patientsPleural effusionCT scan featuresDegree of lymphadenopathyCauses of lymphadenopathyCommunity-acquired pneumoniaChest CT scanStudy exclusion criteriaStudy inclusion criteriaContralateral lymphadenopathyHepatitis CInvolved lobeSmoking historyDifferent comorbiditiesHIV infectionLymph nodesCommon etiologyHIV statusMean ageBlood culturesIntrathoracic lymphadenopathy in hospitalized patients with pneumococcal pneumonia.
Stein D, Haramati L, Spindola-Franco H, Friedman J, Klapper P. Intrathoracic lymphadenopathy in hospitalized patients with pneumococcal pneumonia. CHEST Journal 2005, 127: 1271-5. PMID: 15821204, DOI: 10.1378/chest.127.4.1271.Peer-Reviewed Original ResearchConceptsPrevalence of lymphadenopathyCharacteristics of pneumoniaCT scanPneumococcal pneumoniaIntrathoracic lymphadenopathyHospitalized patientsPleural effusionClinical diagnosis of pneumoniaPresence of pleural effusionCommunity-acquired pneumoniaCT scan featuresEnlarged lymph nodesChest CT scanStudy exclusion criteriaDegree of lymphadenopathyDiagnosis of pneumoniaStudy inclusion criteriaContralateral lymphadenopathyBlood culturesHIV infectionHepatitis CLymph nodesLymphadenopathySmoking historyHIV status
2004
Consistency of reporting basic characteristics of lung nodules and masses on computed tomography1
Burns J, Haramati L, Whitney K, Zelefsky M. Consistency of reporting basic characteristics of lung nodules and masses on computed tomography1. Academic Radiology 2004, 11: 233-237. PMID: 14974599, DOI: 10.1016/s1076-6332(03)00573-7.Peer-Reviewed Original ResearchConceptsAbsence of calcificationBronchogenic carcinomaPathology reportsCT scanLung nodulesDifferential diagnosisPreoperative chest CT scansChest CT scanStandardized reporting criteriaConsecutive patientsPathologic reportsMean ageCT evaluationLobectomy specimensSingle institutionFinal diagnosisLung cancerRadiologic descriptionBoard-certified radiologistsLesion characteristicsCT reportsYears yearsSpiculated marginsPathologic specimensCarcinoma
2002
Role of Computed Tomography in Guiding the Management of Peripheral Bronchopleural Fistula
Ricci Z, Haramati L, Rosenbaum A, Liebling M. Role of Computed Tomography in Guiding the Management of Peripheral Bronchopleural Fistula. Journal Of Thoracic Imaging 2002, 17: 214-218. PMID: 12082373, DOI: 10.1097/00005382-200207000-00006.Peer-Reviewed Original ResearchConceptsPeripheral bronchopleural fistulaBronchopleural fistulaPeripheral bronchiectasisSurgical managementMean age 38 yearsAge 38 yearsChest CT scanPeripheral bronchiMedical chartsChest CTTreatment decisionsLung windowCT scanComputed tomographyFistulaPatientsSurgeryClinical diagnosisLungProbable causeCTBronchiectasisPneumoniaCausePresent study
2001
Newly Diagnosed Pulmonary Sarcoidosis in HIV-infected Patients
Haramati L, Lee G, Singh A, Molina P, White C. Newly Diagnosed Pulmonary Sarcoidosis in HIV-infected Patients. Radiology 2001, 218: 242-246. PMID: 11152809, DOI: 10.1148/radiology.218.1.r01ja25242.Peer-Reviewed Original ResearchConceptsCD4 cell countFocal consolidationCell countPulmonary sarcoidosisReticular opacitiesGranular opacitiesChest radiographsPulmonary nodulesMean CD4 cell countAngiotensin-converting enzyme levelsEnzyme levelsActive antiretroviral therapyGround-glass opacitiesHuman immunodeficiency virusChest CT scanFindings of sarcoidosisManifestations of diseasePulmonary signsTen HIVAntiretroviral therapyRadiologic featuresClinical featuresImmunodeficiency virusRadiographic findingsTomographic scan
2000
Intrathoracic Kaposi's Sarcoma in Women With AIDS
Haramati L, Wong J. Intrathoracic Kaposi's Sarcoma in Women With AIDS. CHEST Journal 2000, 117: 410-414. PMID: 10669683, DOI: 10.1378/chest.117.2.410.Peer-Reviewed Original ResearchConceptsPulmonary Kaposi's sarcomaIntrathoracic Kaposi's sarcomaOropharyngeal Kaposi's sarcomaCD4 cell countHIV risk factorsKaposi's sarcomaPulmonary diseasePleural effusionInterlobular septaPeribronchovascular opacitiesRisk factorsDifferential diagnosisChest radiographsCell countMedian CD4 cell countPatient's pulmonary diseasePrior opportunistic infectionsChest radiographic findingsCutaneous Kaposi's sarcomaTime of diagnosisChest CT scanStaging of diseaseDiffuse lung diseaseAcute hemoptysisPatient age
1997
Effect of HIV status on chest radiographic and CT findings in patients with tuberculosis
Haramati L, Jenny-Avital E, Alterman D. Effect of HIV status on chest radiographic and CT findings in patients with tuberculosis. Clinical Radiology 1997, 52: 31-35. PMID: 9022577, DOI: 10.1016/s0009-9260(97)80302-9.Peer-Reviewed Original ResearchConceptsHIV-negative patientsHIV-positive patientsChest CT scanMediastinal lymphadenopathyHIV statusAtypical infiltrateReactivation tuberculosisCT findingsCT scanBilateral mediastinal lymphadenopathyChest CT findingsFrequent cavitationSignificant differencesChest radiographicClinical chartsCT appearanceRadiographic recordsChest radiographsStudy populationPatientsLymphadenopathyTuberculosisInfiltratesMycobacterium tuberculosisHIV
1996
Pulmonary Pseudonodules on Computed Tomography
Haramati L, Haramati N. Pulmonary Pseudonodules on Computed Tomography. Journal Of Thoracic Imaging 1996, 11: 283-285. PMID: 8892199, DOI: 10.1097/00005382-199623000-00007.Peer-Reviewed Original ResearchConceptsDegenerative arthritisCostochondral junctionMedian ageCostosternal junctionSternoclavicular junctionSerial chest CT scansMedian patient ageChest CT scanPatient ageAerated lungCommon findingLung windowCT scanFirst ribArthritisComputed tomographyOval opacityMusculoskeletal radiologistsPulmonary nodulesPatientsOsseous structuresCT slice thicknessLungAgeTrue pulmonary nodules
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