2025
Hypersensitivity pneumonitis associated with home mold exposure: A retrospective cohort analysis
Adams T, Redlich C, Glazer C, Gulati M. Hypersensitivity pneumonitis associated with home mold exposure: A retrospective cohort analysis. PLOS ONE 2025, 20: e0323093. PMID: 40338891, PMCID: PMC12061107, DOI: 10.1371/journal.pone.0323093.Peer-Reviewed Original ResearchConceptsDiagnosis of HPHP patientsRetrospective cohort of patientsMold exposureTransplant free survivalCohort of patientsRetrospective cohort analysisMedical chart reviewDevelopment of HPHypersensitivity pneumonitis patientsHome moldFibrotic HPFree survivalAntigen exposureChart reviewConfident diagnosisRetrospective cohortPneumonic patientsInvasive proceduresHypersensitivity pneumonitisCohort analysisCulprit antigenPatientsImprove outcomesCohortEvaluation of nonspecific reactivity rates across three immunohematology testing platforms with assessment of subsequent specific alloantibody development
Yurtsever N, Carmichael G, Malonis R, Madden M, Isik N, Ahmed M, Bizzario L, Shah B, Tormey C, Lee E. Evaluation of nonspecific reactivity rates across three immunohematology testing platforms with assessment of subsequent specific alloantibody development. Transfusion 2025 PMID: 40251842, DOI: 10.1111/trf.18256.Peer-Reviewed Original ResearchNonspecific reactivityAntibody screeningStrength of reactivityRate of positivityReagent red cellsAlloantibody developmentKruskal-Wallis testAntibody historyChart reviewPretransfusion testingAntibody identificationIRB approvalIdentification panelKruskal-WallisPositive screenAntibody detectionRed cellsAntibodiesAlloantibodiesStudy periodReactivation rateTube testNonspecific reactionsScreeningCellsCapacity assessment for EHR-based medical device post-market surveillance for synthetic mid-urethral slings among women with stress urinary incontinence: a NEST consortium study
Matheny M, Perkins A, Rieger-Christ K, Ross J, Mao J, Sedrakyan A, Shah N, Winter R, Reynolds W, Mourtzinos A, Schulz W, Bartlett V, Solotke M, Pandya S, Aryal S, Cho A, Frankenberger E, Park D, Bostrom D, Robbins S, Yustein A, Chughtai B, Trabuco E. Capacity assessment for EHR-based medical device post-market surveillance for synthetic mid-urethral slings among women with stress urinary incontinence: a NEST consortium study. BMJ Surgery Interventions & Health Technologies 2025, 7: e000193. PMID: 39949784, PMCID: PMC11822424, DOI: 10.1136/bmjsit-2023-000193.Peer-Reviewed Original ResearchElectronic health record dataElectronic health recordsHealth systemStress urinary incontinenceSynthetic mesh implantsTertiary care academic medical centerSurgical approachManual chart reviewChart reviewAcademic medical centerMedical device surveillanceHealth recordsAdverse event surveillanceMesh implantationUrinary incontinenceDuration of surveillanceAscertainment rateMid-urethral sling (MUSOutcome measuresSynthetic mid-urethral slingsTreat stress urinary incontinenceDetermination of surgical approachEvent surveillanceRetrospective observational studyMedical CenterMisoprostol administration mimicking a febrile transfusion reaction
Yurtsever N, Snyder E. Misoprostol administration mimicking a febrile transfusion reaction. Transfusion 2025, 65: 643-646. PMID: 39907501, DOI: 10.1111/trf.18150.Peer-Reviewed Original ResearchConceptsFebrile nonhemolytic transfusion reactionsTransfusion reactionsBlood culturesSynthetic prostaglandin E1 analogueThermogenic effectAdministration of misoprostolProstaglandin E1 analogueRed cell transfusionTransfusion medicineFebrile transfusion reactionsNonhemolytic transfusion reactionsG1P0 femaleMisoprostol administrationCell transfusionE1 analogueChart reviewSerological workupCase reportDifferential diagnosisEnhance patient satisfactionMisoprostolTransfusionUterotonic propertiesSerological findingsSide effectsMask Anesthesia, Straight Laryngoscope, and Alligator Forceps for Cervical Esophageal Coin Removal: A Comparison with Traditional Methods.
Shah H, Brawley C, Gabra L, Maddalozzo J, Maurrasse S, Johnston D. Mask Anesthesia, Straight Laryngoscope, and Alligator Forceps for Cervical Esophageal Coin Removal: A Comparison with Traditional Methods. Annals Of Otology Rhinology & Laryngology 2025, 34894251318161. PMID: 39905790, DOI: 10.1177/00034894251318161.Peer-Reviewed Original ResearchCoin removalLaryngoscope groupRigid esophagoscopyAnesthesia timeMean operative timeAlligator forcepsPost-operative complicationsRetrospective chart reviewTertiary academic centerInduction of general anesthesiaForeign bodyMask anesthesiaMarkers of efficacyMean anesthesia timeLaryngoscope bladePostoperative complicationsChart reviewMask ventilationMarkers of safetySurgeon preferenceEsophageal coinsGeneral anesthesiaPrimary outcomeIngested foreign bodiesOperative timeInterleukin‐12/23 and Interleukin‐23 Inhibitors for the Treatment of Cutaneous Crohn's Disease: A Case Series From a Multi‐Institutional Registry
McKay G, Coromilas A, Liu L, Shaw K, Murphy M, Punyamurthy N, Soltero K, Damsky W, Wanat K, Charrow A, Rosenbach M, Caplan A, LaSenna C, Arkin L, Shields B. Interleukin‐12/23 and Interleukin‐23 Inhibitors for the Treatment of Cutaneous Crohn's Disease: A Case Series From a Multi‐Institutional Registry. JEADV Clinical Practice 2025 DOI: 10.1002/jvc2.615.Peer-Reviewed Original ResearchCutaneous Crohn's diseaseIL-12/IL-23Inhibitor therapyIL-23Crohn's diseaseInterleukin-12/23Interleukin-23Patients treated with ustekinumabInterleukin-23 inhibitorTreated with vedolizumabMulti-institutional registryIntestinal diseaseIntestinal Crohn's diseaseRetrospective reviewBiologic therapyIL-12/23Intestinal CDPaediatric patientsCase seriesClinical featuresComplete clearanceAdult patientsChart reviewFollow-upGranulomatous conditionsIsolated subsegmental pulmonary embolism identification based on international classification of diseases (ICD)-10 codes and imaging reports
Rashedi S, Bejjani A, Hunsaker A, Aghayev A, Khairani C, McGonagle B, Lo Y, Mahajan S, Caraballo C, Jimenez J, Krishnathasan D, Zarghami M, Monreal M, Barco S, Secemsky E, Klok F, Muriel A, Hussain M, Appah-Sampong A, Rahaghi F, Sadeghipour P, Lin Z, Mojibian H, Aneja S, Konstantinides S, Goldhaber S, Wang L, Zhou L, Jimenez D, Krumholz H, Piazza G, Bikdeli B, Investigators T. Isolated subsegmental pulmonary embolism identification based on international classification of diseases (ICD)-10 codes and imaging reports. Thrombosis Research 2025, 247: 109271. PMID: 39862754, DOI: 10.1016/j.thromres.2025.109271.Peer-Reviewed Original ResearchInternational Classification of Diseases (ICD)-10 codesICD-10International ClassificationPositive predictive valueDischarge diagnosisAccuracy of ICD-10Radiology reportsPrincipal discharge diagnosisSecondary discharge diagnosisIsolated subsegmental pulmonary embolismMedical records of adult patientsHealth systemRecords of adult patientsPredictive valueBlinded re-evaluationExpert radiologistsSubsegmental pulmonary embolismQuality improvementMedical recordsChart reviewPresence of PEProximal PEPulmonary embolismAdult patientsImaging ReportingIdentifying Metabolic Dysfunction-Associated Steatotic Liver Disease Using Natural Language Processing in a US National Cohort.
John B, Bastaich D, Mezzacappa C, Ferreira R, Hentschel A, Samos A, Mahmud N, Taddei T, Kaplan D, Serper M, Dahman B. Identifying Metabolic Dysfunction-Associated Steatotic Liver Disease Using Natural Language Processing in a US National Cohort. The American Journal Of Gastroenterology 2025 PMID: 39950372, DOI: 10.14309/ajg.0000000000003321.Peer-Reviewed Original ResearchElectronic health recordsCardiometabolic risk factorsAlcohol useChart reviewRetrospective study of participantsStudy of participantsLiver diseaseSteatotic liver diseaseIncreased alcohol intakeEligible veteransICD-9/10 codesHealth recordsNational cohortAlcohol intakeEvidence of hepatic steatosisEpidemiological studiesNatural language processing algorithmsRisk factorsStudy cohortOutcome studiesVeteransCohortClinical entityRetrospective studyMetabolic dysfunction
2024
Accuracy of Electronic Health Record Phenotypes to Detect Recognition of Hypertension in Pediatric Primary Care
Nugent J, Cueto V, Tong C, Sharifi M. Accuracy of Electronic Health Record Phenotypes to Detect Recognition of Hypertension in Pediatric Primary Care. Academic Pediatrics 2024, 25: 102629. PMID: 39732164, PMCID: PMC11893226, DOI: 10.1016/j.acap.2024.102629.Peer-Reviewed Original ResearchConceptsPediatric primary careIncident hypertensionHypertensive BPHypertension recognitionPrimary careRecognition of hypertensionCross-sectional study of children aged 3Diagnosis codesElectronic health record phenotypingClinician recognitionClinician decision supportGuideline-recommended careElectronic health recordsInternational Classification of DiseasesChart reviewDocumentation of hypertensionClassification of DiseasesCross-sectional studyChildren aged 3Problem list entriesWellness visitsHealth recordsEHR phenotypesInternational ClassificationICD-10Streptococcus pneumoniae Serotype Distribution Among US Adults Hospitalized With Community-Acquired Pneumonia, 2019–2020
Ramirez J, Hubler R, Ali M, Gray S, Carrico R, McNaughton C, Wunderink R, Dela Cruz C, Chilson E, Cané A, Isturiz R, Pride M, Jodar L, Gessner B, Grant L. Streptococcus pneumoniae Serotype Distribution Among US Adults Hospitalized With Community-Acquired Pneumonia, 2019–2020. Open Forum Infectious Diseases 2024, 12: ofae727. PMID: 39758745, PMCID: PMC11697090, DOI: 10.1093/ofid/ofae727.Peer-Reviewed Original ResearchCommunity-acquired pneumoniaPneumococcal conjugate vaccineStreptococcus pneumoniae</i>Urinary antigen detectionSerotype-specific urinary antigen detectionStreptococcus pneumoniae serotypes distributionUrinary antigen detection assayPneumococcal community-acquired pneumoniaAdult community-acquired pneumoniaRadiographic evidence of community-acquired pneumoniaHigher-valent pneumococcal conjugate vaccinesMedical chart reviewYears of ageCommunity-acquiredSerotype distributionRespiratory samplesChart reviewConjugate vaccineSerotype pneumococciPer-protocolChronic medical conditionsRadiographic evidenceAntigen detectionCoronavirus disease 2019Proportion of adultsPatient Views and Values Placed on the Uterus
Chang O, Huynh A, Ringel N, Hudson P, Halder G, Winkleman W, Ton J, Davidson E, Meriwether K. Patient Views and Values Placed on the Uterus. O&G Open 2024, 1: 048. DOI: 10.1097/og9.0000000000000048.Peer-Reviewed Original ResearchGynecologic conditionsHysterectomy proceduresBenign gynecologic conditionsPelvic organ prolapseProspective cohort studyTreatment of gynecological disordersUterine preservationPelvic painOrgan prolapseMedian agePatient ageUrinary incontinenceChart reviewGynecological disordersCohort studyUterusPatient questionnaireWhite racePatientsMedical CenterHysterectomyPerson-centered careMulticenterGrounded theory approachPhysiological roleGastric Cancer at a Nigerian Tertiary Referral Center: Experiences With Establishing an Institutional Cancer Registry
Yibrehu B, Mohammed T, Murthy S, Aderibigbe A, Daramola O, Arije O, Owoade I, Wuraola F, Olasehinde O, Betiku O, Folorunso S, Omoyiola O, Aderounmu A, Adisa A, Kingham P, Alatise O. Gastric Cancer at a Nigerian Tertiary Referral Center: Experiences With Establishing an Institutional Cancer Registry. Journal Of Surgical Oncology 2024 PMID: 39558548, DOI: 10.1002/jso.27993.Peer-Reviewed Original ResearchInstitutional cancer registryGastric cancerCancer RegistryTreatment modalitiesSuspected gastric cancerManagement of gastric cancerQuality of registry dataTertiary referral centerGastric cancer registryHigh-risk patientsDatabase of patientsGastric cancer databasePeriodic chart reviewMetastatic diseaseAdvanced diseaseReferral centerCancer DatabaseAvailability of robust dataMedian timeChart reviewFollow-upDeadly malignancyBlood workPatientsRegistry dataFive-Year Evaluation of an Anal Cancer Screening Program in Men Who Have Sex With Men With HIV at 2 Academic Center Clinics
Achhra A, Chan E, Applebaum S, Guerrero M, Hao R, Pantel H, Virata M, Fikrig M, Barakat L. Five-Year Evaluation of an Anal Cancer Screening Program in Men Who Have Sex With Men With HIV at 2 Academic Center Clinics. Clinical Infectious Diseases 2024, ciae541. PMID: 39492696, DOI: 10.1093/cid/ciae541.Peer-Reviewed Original ResearchHigh-resolution anoscopyAnal cytologyAnal cancer screening programAbnormal anal cytologyAcademic HIV clinicSquamous cell carcinomaRetrospective chart reviewHistory of smokingEligible populationCancer screening programDetecting HSILAbnormal cytologyTriage testCell carcinomaHIV clinicChart reviewOlder age groupsHSILFollow-upCytologyScreening programScreening testCenter clinicIncreasing ageEligible individualsHPV Status and Oral Health Symptom Patterning During Treatment and Survivorship in Patients With Head and Neck Cancer: A Longitudinal Analysis.
Dunnack Yackel H, Xu W, Wun Lee J, Cong X, Salner A, Duffy V, Judge M. HPV Status and Oral Health Symptom Patterning During Treatment and Survivorship in Patients With Head and Neck Cancer: A Longitudinal Analysis. Oncology Nursing Forum 2024, 51: 565-575. PMID: 39431692, DOI: 10.1188/24.onf.565-575.Peer-Reviewed Original ResearchConceptsHead and neck cancerOral health symptomsHuman papillomavirusNeck cancerHPV-negative head and neck cancersHealth symptomsHuman papillomavirus statusRetrospective longitudinal chart reviewSocial determinants of healthRegional cancer instituteDeterminants of healthLongitudinal chart reviewConcurrent chemotherapyHPV statusRadiation therapyLatent transition analysisChart reviewSymptom patternsSocial determinantsImprove outcomesCancer InstitutePatientsTime pointsEarly interventionLongitudinal analysisUS Clinical Practice Experience with Eculizumab in Myasthenia Gravis: Acute Clinical Events and Healthcare Resource Utilization
Nowak R, Habib A, Klink A, Muppidi S, Parthan A, Sader S, Balanean A, Gajra A, Howard J. US Clinical Practice Experience with Eculizumab in Myasthenia Gravis: Acute Clinical Events and Healthcare Resource Utilization. Drugs - Real World Outcomes 2024, 11: 593-601. PMID: 39470958, PMCID: PMC11589080, DOI: 10.1007/s40801-024-00457-8.Peer-Reviewed Original ResearchHealthcare resource utilizationAssociated healthcare resource utilizationRescue therapy useEculizumab treatmentMyasthenia gravisMG exacerbationEculizumab initiationTherapy useMethodsA retrospective chart reviewTerminal complement inhibitor eculizumabRetrospective chart review analysisRates of healthcare resource utilizationComplement inhibitor eculizumabGeneralized myasthenia gravisRetrospective chart reviewChart review analysisTreatment of patientsUS adultsEculizumab therapyAcute clinical eventsMG crisisRescue therapyChart reviewEculizumabTherapy administrationOverall survival in TP53-mutated AML and MDS
Puzo C, Hager K, Rinder H, Weinberg O, Siddon A. Overall survival in TP53-mutated AML and MDS. Annals Of Hematology 2024, 103: 5359-5369. PMID: 39443370, DOI: 10.1007/s00277-024-06054-7.Peer-Reviewed Original ResearchOverall survivalBlast countTP53 mutationsSignificant predictors of OSP53 mutation typePredictors of OSAggressive disease biologyRetrospective chart reviewKaplan-Meier curvesYale-New Haven HospitalNext generation sequencingCox proportional hazards modelsProportional hazards modelComplex karyotypePoor OSP53 mutationsWHO criteriaChart reviewNew Haven HospitalPoor prognosisCo-mutationsPathogenic mutationsAMLICCS guidelinesMutation typeAssessing the Effect of Changing the Average Hematocrit in Red Blood Cell (RBC) Units on the Post- Procedure Hematocrits of Patients Undergoing Erythrocytapheresis
Musante K, Roome L, Yurtsever N, Rinder H, Tormey C, Lee E. Assessing the Effect of Changing the Average Hematocrit in Red Blood Cell (RBC) Units on the Post- Procedure Hematocrits of Patients Undergoing Erythrocytapheresis. American Journal Of Clinical Pathology 2024, 162: s147-s147. DOI: 10.1093/ajcp/aqae129.326.Peer-Reviewed Original ResearchSickle cell diseaseRed blood cell unitsSickle cell disease patientsRed blood cellsPatient's HctRBC unitsTransfused RBC unitsRetrospective chart reviewTwo-sample t-testChart reviewAdverse eventsMedian numberPre-procedureProphylactic procedureCell diseasePatientsAcademic hospitalAverage hematocritAverage HctBlood cellsHctTransfusion servicesT-testQuality studiesHematocritTrends in Revision Facial Feminization Surgery
Ihnat J, Hu K, Wood S, Sutherland R, Allam O, Parikh N, Alperovich M. Trends in Revision Facial Feminization Surgery. Journal Of Craniofacial Surgery 2024, 36: 769-772. PMID: 39325077, DOI: 10.1097/scs.0000000000010693.Peer-Reviewed Original ResearchFacial feminization surgeryGender-affirming surgeryFeminization surgeryFacial feminization surgery proceduresFacial feminization surgery patientsEnhance surgical outcomesHormone therapySurgical outcomesSurgical approachChart reviewLower BMIManual chart reviewPatient factorsSurgerySmoking statusPatientsTGNB patientsGender-affirming proceduresOlder ageBMIDiagnosis of transsexualismAssociated with differencesOutcomesImprove careAgeErdheim–Chester Disease With Eyelid and Orbital Involvement: A Review of Treatment Modalities at One Institution From 2014 to 2022
Sharma M, Stevens S, Maeng M, Nagornaya N, Bhatia R, Wester S. Erdheim–Chester Disease With Eyelid and Orbital Involvement: A Review of Treatment Modalities at One Institution From 2014 to 2022. Ophthalmic Plastic And Reconstructive Surgery 2024, 40: 497-503. PMID: 38427815, PMCID: PMC11377047, DOI: 10.1097/iop.0000000000002619.Peer-Reviewed Original ResearchErdheim-Chester diseaseBascom Palmer Eye InstituteEye InstituteOrbital involvementTreatment of Erdheim-Chester diseaseErdheim-Chester disease patientsCase of Erdheim-Chester diseaseIntolerable side effectsRetrospective chart reviewFavorable treatment optionRelevant laboratory resultsReview of treatmentOphthalmic examinationDry eyeOphthalmic symptomsReducing proptosisBRAF inhibitorsECD patientsPathology reportsOphthalmic institutionsOrbital diseaseChart reviewTreatment modalitiesErdheim-ChesterPrimary treatmentP22: Comparative Analysis of Efficacy of Intravenous Ketamine and Intranasal Esketamine in Treatment-Resistant Depression across Age Groups
Hutchison C, Hermida A, Keshishyan A, Kitay B, Chatham A, Hershenberg R, Posse P, Posse P. P22: Comparative Analysis of Efficacy of Intravenous Ketamine and Intranasal Esketamine in Treatment-Resistant Depression across Age Groups. International Psychogeriatrics 2024, 36: 130-131. DOI: 10.1017/s1041610224002552.Peer-Reviewed Original ResearchBeck Depression InventoryIntravenous ketamineIntranasal esketamineTreatment-resistant depressionRetrospective chart reviewAge groupsResistant depressionClinical responseDepression InventorySymptomatic improvementTreatment resistanceChart reviewEsketamineAcute coursePatientsDepressionKetamineTRDAgeBeckIntranasalInfusionGroupInventory
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