2025
Diaphragm Dysfunction from Phrenic Nerve Injures During LVAD or Heart Transplant: Positive Role of Diaphragm Pacing
Boutros C, Elmo M, Carl N, Abu-Omar Y, Arora R, Elgudin Y, Gray K, Pelletier M, Onders R. Diaphragm Dysfunction from Phrenic Nerve Injures During LVAD or Heart Transplant: Positive Role of Diaphragm Pacing. JHLT Open 2025, 100281. DOI: 10.1016/j.jhlto.2025.100281.Peer-Reviewed Original ResearchNon-invasive ventilationLeft ventricular assist deviceDiaphragm pacingHeart transplantationMechanical ventilationNerve injurySingle-center cohort studyPhrenic nerve dysfunctionPhrenic nerve injuryLeft ventricular assist device recipientsPhrenic injuryDiaphragm dysfunctionDifficulty weaningNerve dysfunctionNerve injuresCase seriesDiaphragm functionMV weaningDP useAdverse eventsCohort studyVentricular assist deviceHTxExploratory case seriesTransplantationCraniosynostosis among children with X-linked hypophosphatemia: A systematic review and meta-analysis
Fisch S, Tudor A, Benchekroun E, Landsberg W, Feldstein N, Lamb M, Carpenter T, Rundle A, Jacobson J, Neugut A, Freedberg D. Craniosynostosis among children with X-linked hypophosphatemia: A systematic review and meta-analysis. Bone 2025, 196: 117488. PMID: 40220947, DOI: 10.1016/j.bone.2025.117488.Peer-Reviewed Original ResearchX-linked hypophosphatemiaPrevalence of craniosynostosisPooled prevalenceSystematic reviewMeta-analysisRandom-effects modelWeb of SciencePediatric populationSkull abnormalitiesCohort studyImpaired phosphate reabsorptionElevated FGF23 levelsPrevalenceFemale predominanceCase seriesFGF23 levelsPhosphate reabsorptionGene variantsChildrenIncreased vigilanceCraniosynostosisAbnormal bone growthGenetic disordersHypophosphatemiaAbnormalitiesSystemic chemotherapy in patients with unresectable pseudomyxoma peritonei from low-grade appendiceal mucinous neoplasms: a case series
Vierra M, Morgan R, Ostowari A, Turaga K, Shergill A, Eng O. Systemic chemotherapy in patients with unresectable pseudomyxoma peritonei from low-grade appendiceal mucinous neoplasms: a case series. Journal Of Gastrointestinal Oncology 2025, 16: 757-765. PMCID: PMC12078827, DOI: 10.21037/jgo-24-440.Peer-Reviewed Original ResearchLow-grade appendiceal mucinous neoplasmProgression-free survivalSystemic chemotherapyAppendiceal mucinous neoplasmPseudomyxoma peritoneiCase seriesCarcinoembryonic antigenMucinous neoplasmsFolinic acidAnti-vascular endothelial growth factorMedian progression-free survivalCEA responseMetastatic peritoneal diseaseElevated carcinoembryonic antigenPeritoneal cancer indexMedian follow-upBenefit of chemotherapyResponse to chemotherapyCycles of chemotherapyOutcomes of patientsTreated 5 patientsUniversity of Chicago Medical CenterEndothelial growth factorUnresectable diseasePeritoneal diseaseAdvancing Telemedicine Using Smart Insulin Pens with Continuous Glucose Monitoring and Telecommunication Systems: A Case Series
Singh L, Gothong C, Ash G, Hernandez R, Spanakis E. Advancing Telemedicine Using Smart Insulin Pens with Continuous Glucose Monitoring and Telecommunication Systems: A Case Series. Journal Of Clinical Medicine 2025, 14: 1794. PMID: 40142601, PMCID: PMC11943169, DOI: 10.3390/jcm14061794.Peer-Reviewed Original ResearchCare deliveryModels of care deliveryDiabetes self-care behaviorsMethods of care deliveryImprove patient engagementSelf-care behaviorsMultiple daily injectionsSelf-management capabilitiesPatient engagementInsulin pensTelecommunication modalitiesVisual educational toolComprehensive telemedicine systemManagement of glycemic controlDietary educationAdvanced telemedicineCase seriesTelemedicine systemType 1 diabetes mellitusEducational toolTelemedicineUncontrolled T1DMGlucose dataGlycemic controlDiabetesInjury to Internal Thoracic Artery to Left Anterior Descending Artery Grafts in Cardiac Reoperations
Insler J, Ramsingh R, Bakhos J, Houghtaling P, Koprivanac M, Svensson L, Blackstone E, Bakaeen F. Injury to Internal Thoracic Artery to Left Anterior Descending Artery Grafts in Cardiac Reoperations. JAMA Surgery 2025, 160: 354-356. PMID: 39661360, PMCID: PMC11904727, DOI: 10.1001/jamasurg.2024.4952.Peer-Reviewed Original ResearchEliglustat substrate reduction therapy in children with Gaucher disease type 1
Ain N, Saith A, Ruan A, Yang R, Burton A, Mistry P. Eliglustat substrate reduction therapy in children with Gaucher disease type 1. Frontiers In Pediatrics 2025, 13: 1543136. PMID: 40083427, PMCID: PMC11903696, DOI: 10.3389/fped.2025.1543136.Peer-Reviewed Original ResearchEnzyme replacement therapySubstrate reduction therapyGD1 patientsPediatric patientsReduction therapyOral substrate reduction therapyPrimary outcomeAlternative to enzyme replacement therapyIntravenous enzyme replacement therapyLevels compared to baselineGaucher disease type 1Indicator of disease activityParent-reported qualityCYP2D6 metabolizer statusRare lysosomal storage disorderProspective case seriesGaucher diseaseType 1 Gaucher diseaseQuality of lifeDisease indicationsLysosomal storage disorderPROMIS questionnairesReplacement therapyCase seriesClinical benefitPre-operative internal maxillary artery embolization for temporomandibular joint replacement: safety and outcomes from a 10-year institutional experience
Sujijantarat N, Padmanaban V, Smith W, McCain J, Kaban L, Burris B, Choi D, Larson A, Elsamadicy A, Serrato P, Dabus G, Regenhardt R, Stapleton C, Patel A, Rabinov J. Pre-operative internal maxillary artery embolization for temporomandibular joint replacement: safety and outcomes from a 10-year institutional experience. Journal Of NeuroInterventional Surgery 2025, jnis-2024-022975. PMID: 39904620, DOI: 10.1136/jnis-2024-022975.Peer-Reviewed Original ResearchTemporomandibular joint replacementInternal maxillary arteryBlood lossMiddle meningeal arteryHistorical controlsEmbolization-related complicationsVolume blood lossIntra-procedural complicationsFemoral artery dissectionEmbolization cohortRandomized controlled trialsArtery embolizationCase seriesTreatment detailsAdult patientsHistorical cohortArtery dissectionExcessive hemorrhageInstitutional experienceFollow-upMaxillary arteryMeningeal arteryEmbolizationPubMed searchJoint replacementPOCUS the Pelvis: A Case Series of Timely Diagnoses in Pediatric Patients With Abdominal Pain.
Leviter J, Shah R, Constantine E, Riera A. POCUS the Pelvis: A Case Series of Timely Diagnoses in Pediatric Patients With Abdominal Pain. Pediatric Emergency Care 2025 PMID: 39895170, DOI: 10.1097/pec.0000000000003348.Peer-Reviewed Original ResearchThe Use of Extended-Release Buprenorphine in the Treatment of Adolescent Opioid Use Disorder: A Case Series.
Neptune A, Kaliamurthy S. The Use of Extended-Release Buprenorphine in the Treatment of Adolescent Opioid Use Disorder: A Case Series. Journal Of Addiction Medicine 2025 PMID: 39898524, DOI: 10.1097/adm.0000000000001447.Peer-Reviewed Original ResearchExtended-release buprenorphineOpioid use disorderCase seriesUse disorderOpioid abstinenceMedical recordsTreatment of opioid use disorderChart review periodNo significant complicationsDuration of treatmentOnset of treatmentMedical records of adolescentsRecords of adolescentsExtended-releaseSublingual buprenorphinePatient ageSignificant complicationsSubcutaneous injectionOpioidBuprenorphinePatientsOutpatient settingTreatment approachesElectronic medical recordsTreatment retentionMild Malformation of Cortical Development With Oligodendroglial Hyperplasia and Epilepsy
Zhan Y, Chen S, Jin Z, Zhou J, Zhang Y, Hou Q, Wang Y, Zheng G, Zheng Y. Mild Malformation of Cortical Development With Oligodendroglial Hyperplasia and Epilepsy. Neurology Genetics 2025, 11: e200240. PMID: 39902276, PMCID: PMC11790282, DOI: 10.1212/nxg.0000000000200240.Peer-Reviewed Original ResearchMild malformation of cortical developmentMalformations of cortical developmentMild malformationCase reportOligodendroglial hyperplasiaCortical developmentFavorable surgical outcomeNinety-five patientsForty-five patientsDrug-resistant epilepsyLennox-Gastaut syndromeSystematic reviewSelection of treatmentAge-dependent phenotypeRisk of biasRare entityEpileptic spasmsMedian ageSurgical outcomesHistopathological diagnosisInterictal EEGVariant statusSeizure outcomeCase seriesWest syndromeColorectal adenosquamous carcinoma: clinicopathologic analysis of two large cohorts and literature review confirm poor prognosis and reveal prognostic aspects
Gonzalez R, Horton R, Zhang X, Graham R, Longacre T, Mehrotra A, Allende D, McHugh K, Shia J, Westerhoff M, Srivastava A, Chen W, Vazzano J, Swanson P, Chatterjee D, Cheema H, Ma C, Mannan R, Chetty R, Nowak K, Serra S, Agostini‐Vulaj D, Kazemimood R, Henn P, Kakar S, Choi W, Adeyi O, Jenkins S, Nagtegaal I. Colorectal adenosquamous carcinoma: clinicopathologic analysis of two large cohorts and literature review confirm poor prognosis and reveal prognostic aspects. Histopathology 2025 PMID: 39887413, DOI: 10.1111/his.15412.Peer-Reviewed Original ResearchTumor-infiltrating lymphocytesAdenosquamous carcinomaColorectal adenosquamous carcinomaTumor buddingPoor prognosisMedian time to progressionMeta-analysis of cohortLow tumor buddingTime to progressionMale:female ratioReview of casesIndividual case seriesNodal metastasisRecurrent diseaseSquamous componentPatient ageRecurrence rateAcademic medical centreCase seriesImmunohistochemical featuresPrognostic aspectsClinicopathological analysisFemale ratioFollow-upColorectal cancerRobotic Congenital Cardiac Surgery Practice Worldwide: A Systematic Review
Lee M, Amabile A, Hameed I, Antonios J, Awad A, Brackett A, Krane M, Gruber P, Geirsson A. Robotic Congenital Cardiac Surgery Practice Worldwide: A Systematic Review. Journal Of Cardiac Surgery 2025, 2025 DOI: 10.1155/jocs/4692522.Peer-Reviewed Original ResearchCase reportTreatment of congenital heart diseaseAdult cardiac surgery patientsHighest incidence of morbidityCannulation-related complicationsImproved surgeon experienceCongenital heart diseaseCardiac surgery patientsSmall case seriesIncidence of morbidityIndependent reviewers screened titles/abstractsInconsistent outcome reportingNewcastle-Ottawa ScaleNonrandomized observational studyCardiac surgery operationsComprehensive literature searchCongenital operationsCongenital diagnosisCongenital surgeryPediatric patientsPleural effusionCase seriesRetrospective studySurgeon experienceHeart blockRegional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (fifth edition)
Kopp S, Vandermeulen E, McBane R, Perlas A, Leffert L, Horlocker T. Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (fifth edition). Regional Anesthesia & Pain Medicine 2025, rapm-2024-105766. PMID: 39880411, DOI: 10.1136/rapm-2024-105766.Peer-Reviewed Original ResearchAmerican Society of Regional AnesthesiaDeep venous thrombosisEvidence-based guidelinesRegional anesthesiaThrombolytic therapyComplications associated with regional anesthesiaRecurrent deep venous thrombosisAmerican SocietyRandomized controlled trialsAnticoagulant doseNeural blockadeVenous thrombosisCase seriesCatastrophic complicationPatient characteristicsClinical trialsHigh dosesPatientsPublished guidelinesControlled trialsPainAnesthesiaPatient safetyTherapyDoseInterleukin‐12/23 and Interleukin‐23 Inhibitors for the Treatment of Cutaneous Crohn's Disease: A Case Series From a Multi‐Institutional Registry
McKay G, Coromilas A, Liu L, Shaw K, Murphy M, Punyamurthy N, Soltero K, Damsky W, Wanat K, Charrow A, Rosenbach M, Caplan A, LaSenna C, Arkin L, Shields B. Interleukin‐12/23 and Interleukin‐23 Inhibitors for the Treatment of Cutaneous Crohn's Disease: A Case Series From a Multi‐Institutional Registry. JEADV Clinical Practice 2025 DOI: 10.1002/jvc2.615.Peer-Reviewed Original ResearchCutaneous Crohn's diseaseIL-12/IL-23Inhibitor therapyIL-23Crohn's diseaseInterleukin-12/23Interleukin-23Patients treated with ustekinumabInterleukin-23 inhibitorTreated with vedolizumabMulti-institutional registryIntestinal diseaseIntestinal Crohn's diseaseRetrospective reviewBiologic therapyIL-12/23Intestinal CDPaediatric patientsCase seriesClinical featuresComplete clearanceAdult patientsChart reviewFollow-upGranulomatous conditionsBeyond convention: non-compacted myocardium, ventricular tachycardia, and systolic dysfunction in dextrocardia patients: a case series
Nazarenko N, Maliha M, Cerna L, Abittan N, Borkowski P, Csecs I, Garcia M. Beyond convention: non-compacted myocardium, ventricular tachycardia, and systolic dysfunction in dextrocardia patients: a case series. Annals Of Medicine And Surgery 2025, 87: 56-61. PMID: 40109641, PMCID: PMC11918691, DOI: 10.1097/ms9.0000000000002855.Peer-Reviewed Original ResearchLeft ventricleDextrocardia patientsICD placementSeverely reduced ejection fractionHigh risk of sudden cardiac deathRight-sided pleural effusionRisk of sudden cardiac deathAbnormal myocardial developmentYears of follow-upNon-compacted myocardiumTreated with amiodaroneSubsegmental pulmonary embolismTreated with enoxaparinLong-term outcomesSudden cardiac deathSystolic dysfunctionEvent-freeWorsening dyspneaEjection fractionPulmonary embolismAtrial dilatationPleural effusionConduction abnormalitiesMedical therapyCase seriesThe Spectrum of Cutaneous and Systemic Manifestations Associated with Anti-PM/Scl: Insights from a Single Institution Case Series
Saeed S, Gehlhausen J, Koumpouras F, Ramachandran S. The Spectrum of Cutaneous and Systemic Manifestations Associated with Anti-PM/Scl: Insights from a Single Institution Case Series. Journal Of The American Academy Of Dermatology 2025 PMID: 39756619, DOI: 10.1016/j.jaad.2024.12.033.Peer-Reviewed Original ResearchOral health and rehabilitation in face transplant recipients – a systematic review
Knoedler L, Kauke-Navarro M, Knoedler S, Niederegger T, Hofmann E, Heiland M, Koerdt S, Nahles S, Baecher H. Oral health and rehabilitation in face transplant recipients – a systematic review. Clinical Oral Investigations 2025, 29: 47. PMID: 39760761, PMCID: PMC11703954, DOI: 10.1007/s00784-024-06078-3.Peer-Reviewed Original ResearchConceptsNewcastle-Ottawa ScaleLevel of evidenceOral healthFT patientsLong-term transplant successNewcastle-Ottawa Scale scoreOral health protocolOral health assessmentSevere facial defectsFT recipientsOral mucosa biopsiesImproving clinical outcomesSystematic reviewFace transplant recipientsFailed osseointegrationEndodontic treatmentDental treatmentFT caseTooth extractionTransplant recipientsDental implantsOverall patient healthOral mucosaStandard care protocolCase series
2024
Most Patients Report Acceptable Knee Function, Satisfaction, and Clinical Outcomes at a Minimum Ten Years Following Quadriceps Free Tendon Anterior Cruciate Ligament Reconstruction
Hewitt C, Kostyun R, Fulkerson J, Shuman M, Rios C. Most Patients Report Acceptable Knee Function, Satisfaction, and Clinical Outcomes at a Minimum Ten Years Following Quadriceps Free Tendon Anterior Cruciate Ligament Reconstruction. Arthroscopy Sports Medicine And Rehabilitation 2024, 101062. DOI: 10.1016/j.asmr.2024.101062.Peer-Reviewed Original ResearchAnterior cruciate ligament reconstructionTime of surgeryClinical outcomesCruciate ligament reconstructionKnee functionRe-injuryMental healthSubjective functionFollow-upOutcomes of anterior cruciate ligament reconstructionLigament reconstructionHealth and WellbeingConcomitant cartilage proceduresContralateral ACL injuryTherapeutic case seriesSubjective knee functionMulti-ligament reconstructionLong-term outcomesRetrospective chart review designPhysical functionACL injuryConcomitant proceduresCase seriesConcomitant injuriesHealth conclusionsLong-term posttransplant-related bone volumetric changes in eight face transplant recipients – A single-center retrospective case series
Huelsboemer L, Boroumand S, Boroumand T, Vafa A, Parikh N, Chiarella L, Knoedler L, Stögner V, Hung P, Sadigh S, Haykal S, Pomahac B, Kauke-Navarro M. Long-term posttransplant-related bone volumetric changes in eight face transplant recipients – A single-center retrospective case series. Journal Of Plastic Reconstructive & Aesthetic Surgery 2024, 101: 220-230. PMID: 39848075, DOI: 10.1016/j.bjps.2024.11.025.Peer-Reviewed Original ResearchFacial vascularized composite allograftBone volume changesBone volumeChronic rejection processRetrospective case seriesComputed tomography scanBone volume lossWilcoxon rank sum testNative boneSignificant median decreaseBone volume stabilityRank sum testFace transplant recipientsBone remodeling ratesVascularized composite allograftsChronic immunosuppressionTooth lossTransplant recipientsAllograft cohortCase seriesTomography scanVolume lossMedian decreaseMedical comorbiditiesHistopathological analysisIntravenous Infusion of Autologous Mesenchymal Stem Cells Expanded in Auto Serum for Chronic Spinal Cord Injury Patients: A Case Series
Hirota R, Sasaki M, Iyama S, Kurihara K, Fukushi R, Obara H, Oshigiri T, Morita T, Nakazaki M, Namioka T, Namioka A, Onodera R, Kataoka-Sasaki Y, Oka S, Takemura M, Ukai R, Yokoyama T, Sasaki Y, Yamashita T, Kobayashi M, Okuma Y, Kondo R, Aichi R, Ohmatsu S, Kawashima N, Ito Y, Kobune M, Takada K, Ishiai S, Ogata T, Teramoto A, Yamashita T, Kocsis J, Honmou O. Intravenous Infusion of Autologous Mesenchymal Stem Cells Expanded in Auto Serum for Chronic Spinal Cord Injury Patients: A Case Series. Journal Of Clinical Medicine 2024, 13: 6072. PMID: 39458022, PMCID: PMC11509003, DOI: 10.3390/jcm13206072.Peer-Reviewed Original ResearchAmerican Spinal Injury Association Impairment ScaleSevere spinal cord injuryMesenchymal stem cell infusionAutologous mesenchymal stem cellsIntravenous infusionCase seriesMesenchymal stem cellsQuality of lifeAuto-serumSpinal cord injuryFunctional improvementChronic spinal cord injury patientsIntravenous infusion of mesenchymal stem cellsInfusion of mesenchymal stem cellsStem cellsCord injurySpinal Cord Independence Measure IIIAmerican Spinal Injury Association Impairment Scale grades CSpinal cord injury patientsChronic SCI patientsClassification of Spinal Cord InjuryNeurological Classification of Spinal Cord InjurySignificant functional improvementAssociation Impairment ScaleInternational Standards for Neurological Classification of Spinal Cord Injury
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