2025
Screening History, Stage at Diagnosis, and Mortality in Screen-Detected Breast Cancer
Huang S, Westvold S, Soulos P, Fan J, Winer E, Zhan H, Lustberg M, Lewin J, Robinson T, Dinan M. Screening History, Stage at Diagnosis, and Mortality in Screen-Detected Breast Cancer. JAMA Network Open 2025, 8: e255322. PMID: 40232715, DOI: 10.1001/jamanetworkopen.2025.5322.Peer-Reviewed Original ResearchConceptsBreast cancer-specific mortalityBreast cancer mortalityBreast cancer diagnosisCancer-specific mortalityCancer mortalityCancer diagnosisScreening mammographyHazard of breast cancer-specific deathFee-for-service Medicare Parts AAssociated with reduced breast cancer mortalityLower breast cancer mortalityHazard of breast cancer-specific mortalityBreast cancerImprove breast cancer outcomesScreen-detected breast cancerCohort studyBreast cancer-specific deathStudy of older womenBreast cancer outcomesFee-for-serviceDetection of breast cancerMedicare Part ALater-stage diseaseCox proportional hazards modelsAssociated with early stagesUrology on a changing planet: links between climate change and urological disease
Cole A, Qian Z, Gupta N, Leapman M, Zurl H, Trinh Q, Sherman J, Loeb S, Iyer H. Urology on a changing planet: links between climate change and urological disease. Nature Reviews Urology 2025, 1-15. PMID: 39875561, DOI: 10.1038/s41585-024-00979-4.Peer-Reviewed Original ResearchCare deliveryHealth care delivery strategiesCancer care deliveryCare delivery strategiesHealth care deliveryLow-value careResource-intensive interventionsEnvironmental risk factorsCare providersIntensive longitudinal assessmentCancer diagnosisPlanetary healthRisk factorsDownstream outcomesLongitudinal assessmentHealthNext stepsUrological cancersImpacts of climate-related disastersClimate changeUrological diseasesDeliveryCareProvidersTelemedicinePersonalized frailty risk assessment in long-term survivors of colorectal cancer.
Forman R, Westvold S, Long J, Fan J, Hyslop T, Yasin F, Conlin K, Jacobson S, Silber A, Wang S, Leapman M, Leeds I, Cecchini M, Spees L, Wheeler S, Gross C, Oeffinger K, Dinan M. Personalized frailty risk assessment in long-term survivors of colorectal cancer. Journal Of Clinical Oncology 2025, 43: 65-65. DOI: 10.1200/jco.2025.43.4_suppl.65.Peer-Reviewed Original ResearchRectal cancer survivorsCancer survivorsElixhauser Comorbidity IndexLong-term survivors of colorectal cancerSurvivors of colorectal cancerClinical prediction modelStage I-III colonCancer diagnosisGastrointestinal cancer survivorsYear 4Area-level povertyAssociated with reduced qualityRisk of frailtyProportion of residentsOnset of frailtyPredictors of frailtyFederal poverty lineIncreased risk of deathAdministrative claims codesSurvivorship managementRisk of deathRetrospective cohort studyAssociated with shorter timePatient raceSevere frailtyEvaluation of social support, discrimination, and perceived health in patients with gastrointestinal tract cancers.
Butensky S, Kim J, Godfrey E, Su D, Kerekes D, Johnson C, Ahuja N, Khan S. Evaluation of social support, discrimination, and perceived health in patients with gastrointestinal tract cancers. Journal Of Clinical Oncology 2025, 43: 802-802. DOI: 10.1200/jco.2025.43.4_suppl.802.Peer-Reviewed Original ResearchSocial determinants of healthQuality of lifeDeterminants of healthPerceived healthMental healthSocial supportCancer diagnosisSocial determinantsEvaluation of social supportGastrointestinal cancerCancer statusNon-cancerTime of cancer diagnosisGI cancer diagnosisProportion of cancersHealthcare discriminationDeprivation indexNon-HispanicHealth domainsCancer outcomesGeneral healthSurvey scoresGastrointestinal cancer patientsGastrointestinal tract cancerHealthPredictors of late recurrence of colorectal cancer (CRC) among older long-term survivors using claims-based evidence.
Yasin F, Westvold S, Long J, Fan J, Hyslop T, Leeds I, Cecchini M, Gross C, Dinan M. Predictors of late recurrence of colorectal cancer (CRC) among older long-term survivors using claims-based evidence. Journal Of Clinical Oncology 2025, 43: 66-66. DOI: 10.1200/jco.2025.43.4_suppl.66.Peer-Reviewed Original ResearchCRC-specific mortalityAll-cause mortalityCancer diagnosisColorectal cancerLong-term CRC survivorsNon-cancer related conditionsNon-metastatic colorectal cancerSEER-MedicareRisk of all-cause mortalityRecurrence of colorectal cancerColon cancerSEER-Medicare populationYear 5CRC survivorsSEER-Medicare databaseSurvivorship careRectal cancerFollow-up accountsColorectal cancer recurrenceMultiple co-morbiditiesMedicare claimsRetrospective cohort studyFine-Gray modelEstimate cumulative incidencePrimary risk factorSelf-affirmation intervention for patients newly diagnosed with advanced cancer: a preliminary efficacy trial
Bai M, Cella D, Jeon S, Govindarajan R, Birrer M. Self-affirmation intervention for patients newly diagnosed with advanced cancer: a preliminary efficacy trial. Journal Of Psychosocial Oncology 2025, ahead-of-print: 1-23. PMID: 39812781, DOI: 10.1080/07347332.2025.2450013.Peer-Reviewed Original ResearchFunctional Assessment of Cancer Therapy - GeneralAdvanced cancerCancer patients' quality of lifeFACIT-Sp-12Functional assessmentInterrupted time series designPost-intervention changesCancer patients' qualityTime series designQuality of lifePatients' quality of lifePost-interventionPsychosocial interventionsAdvanced stage cancerLinear mixed modelsGeneralized linear mixed modelsSeries designPreliminary efficacyCancer diagnosisIntent-to-treat analysisSelf-affirmation interventionChanges pre-Existential concernsIntervention approachesItem scale
2024
Psilocybin: From Psychiatric Pariah to Perceived Panacea
Fonzo G, Wolfgang A, Barksdale B, Krystal J, Carpenter L, Kraguljac N, Grzenda A, McDonald W, Widge A, Rodriguez C, Nemeroff C. Psilocybin: From Psychiatric Pariah to Perceived Panacea. American Journal Of Psychiatry 2024, 182: 54-78. PMID: 39741437, PMCID: PMC11694823, DOI: 10.1176/appi.ajp.20230682.Peer-Reviewed Original ResearchConceptsPsychiatric disordersTreatment of obsessive-compulsiveTreatment of psychiatric disordersTreatment of MDDSubstance use disordersEvidence-based treatmentsObsessive-compulsiveDepressive disorderEvidence basePsychiatric treatmentExpectancy effectsRandomized controlled trialsPsilocybinPredictors of responseDiverse sampleMechanism of actionDisordersHead-to-head comparisonsEnglish-language articlesKnowledge of mechanisms of actionOpen-labelClinical responseDosing considerationsImproved blindingCancer diagnosisIdentifying diagnosed major chronic diseases associated with recent housing instability among aging adults: data from the ‘All of Us’ research program
Beydoun H, Vieytes C, Beydoun M, Lampros A, Tsai J. Identifying diagnosed major chronic diseases associated with recent housing instability among aging adults: data from the ‘All of Us’ research program. Journal Of Public Health 2024, 47: 15-23. PMID: 39586798, DOI: 10.1093/pubmed/fdae300.Peer-Reviewed Original ResearchUs Research ProgramHousing instabilityAging adultsChronic diseasesOdds ratioChronic disease preventionAssociated with lower oddsPsychiatric diagnosisConfidence intervalsElectronic health recordsAssociated with psychiatric diagnosesEstimate odds ratiosCardiovascular diseaseMultivariate logistic regression modelDiverse group of adultsLogistic regression modelsTreatment of chronic diseasesCross-sectional dataHealth recordsHealthcare utilizationLower oddsGroup of adultsYears of ageDiagnosed diabetesCancer diagnosisAssociation Between Environmental Air Pollution and Thyroid Cancer and Nodules: A Systematic Review
Vohra V, Yesantharao L, Stemme R, Seal S, Morris-Wiseman L, McAdams-DeMarco M, Mady L, Deziel N, Biswal S, Ramanathan M, Mathur A. Association Between Environmental Air Pollution and Thyroid Cancer and Nodules: A Systematic Review. Thyroid 2024, 34: 1451-1464. PMID: 39552469, DOI: 10.1089/thy.2024.0317.Peer-Reviewed Original ResearchConceptsAir pollutionPolyaromatic hydrocarbonsEnvironmental air pollutionThyroid cancer diagnosisConcentrations of PM<sub>2.5</subBlood Institute quality assessment toolCancer diagnosisStudy designPollution assessment methodsSystematic reviewInclusion criteriaGlobal incidence of thyroid cancerOutdoor air pollutionQuality assessment toolMagnitude of associationIncidence of thyroid cancerRisk of biasQuality of evidencePollution levelsSystematic literature searchWeb of ScienceParticulate matterSpecific pollutantsLevels of COSOThyroid Cancer Incidence During 2020 to 2021 COVID-19 Variant Waves
Bell R, Weinberger D, Venkatesh M, Fernandes-Taylor S, Francis D, Davies L. Thyroid Cancer Incidence During 2020 to 2021 COVID-19 Variant Waves. JAMA Otolaryngology - Head & Neck Surgery 2024, 150: 969-977. PMID: 39388144, PMCID: PMC11581733, DOI: 10.1001/jamaoto.2024.3146.Peer-Reviewed Original ResearchThyroid cancer incidenceThyroid cancer diagnosisCancer incidenceUS adultsCancer diagnosisRates of thyroid cancer diagnosisUndiagnosed casesThyroid cancer casesIncidence of thyroid cancerCases of thyroid cancerAdvanced stage cancerMain OutcomesCancer casesUS populationHistological typeIncidence rateThyroid cancerPopulation morbiditySize of cancerStudy analyzed trendsQuarterly ratesFollicular cancerMedullary cancerPapillary cancerAnaplastic cancerIs federal housing assistance associated with earlier-stage cancer diagnosis? Evidence from the new SEER-Medicare and US Department of Housing and Urban Development data linkage.
Yabroff R, Blackford A, Fan Q, Hussaini S, Chen K, Polsky D, Katana Ogongo M, Warren J, Gross C, Pollack C. Is federal housing assistance associated with earlier-stage cancer diagnosis? Evidence from the new SEER-Medicare and US Department of Housing and Urban Development data linkage. Journal Of Clinical Oncology 2024, 20: 85-85. DOI: 10.1200/op.2024.20.10_suppl.85.Peer-Reviewed Original ResearchFederal housing assistanceHousing assistanceUS Department of HousingDepartment of HousingSocial determinants of healthDeterminants of healthCancer outcomesSEER-MedicareHousing insecurityCancer diagnosisSocioeconomic status indexSocial determinantsRural/urban residenceAdministrative dataMarital statusLogistic regression modelsHousingYear of diagnosisMedicaid eligibilityCancer sitesData linkagePercentage of individualsMedicare entitlementPre-diagnosisOdds ratioPerceptions of Delayed Alopecia Among Breast Cancer Survivors
Premji S, Ruddy K, Vierkant R, Larson N, Loprinzi C, Dulmage B, Lustberg M, Couch F, Olson J, Cathcart-Rake E. Perceptions of Delayed Alopecia Among Breast Cancer Survivors. Clinical Breast Cancer 2024, 25: e170-e177. PMID: 39592290, PMCID: PMC11769767, DOI: 10.1016/j.clbc.2024.09.008.Peer-Reviewed Original ResearchBreast cancer survivorsMayo Clinic Breast Disease RegistryCancer survivorsChemotherapy recipientsStage I-III breast cancerI-III breast cancerBreast cancer diagnosisPersistent bothersome symptomsRespondents' median ageBreast cancer treatmentMental healthDistressing symptomsDisease RegistryCancer diagnosisCohort studyHair lossSurvivorsBreast cancerBothersome symptomsBreastRespondentsSurvey 6 yearsParticipantsBotherCancer treatmentAccessing breast cancer care in a protracted conflict: Qualitative exploration of the perspectives of women with breast cancer in northwest Syria
Marzouk M, Hamze M, Debel J, Alshemali A, Alameen B, Bakkour M, Galal B, Chagpar A, Atassi B, Khoshnood K, Abbara A. Accessing breast cancer care in a protracted conflict: Qualitative exploration of the perspectives of women with breast cancer in northwest Syria. Social Science & Medicine 2024, 361: 117364. PMID: 39357306, DOI: 10.1016/j.socscimed.2024.117364.Peer-Reviewed Original ResearchSyrian American Medical SocietyBreast cancer carePerspective of womenSemi-structured interviewsCancer careExperiences of accessing careBreast cancerAmerican Medical SocietyBreast cancer diagnosisAvailability of radiotherapyThematic saturationAccessing careHealthcare staffOncology careNorthwest SyriaPeer supportSocial supportThematic analysisClinical careFinancial strainMultiple intersectional challengesCancer diagnosisCareAccess diagnosisHospital recordsDomestic radon exposure and childhood cancer risk by site and sex in 727 counties in the United States, 2001–2018
Bozigar M, Konstantinoudis G, Zilli Vieira C, Li L, Alwadi Y, Jones R, Koutrakis P. Domestic radon exposure and childhood cancer risk by site and sex in 727 counties in the United States, 2001–2018. The Science Of The Total Environment 2024, 954: 176288. PMID: 39278504, DOI: 10.1016/j.scitotenv.2024.176288.Peer-Reviewed Original ResearchChildhood cancer riskDomestic radon exposureCancer riskRadon exposureIncident cancer diagnosisNational Cancer Institute's SurveillanceChildhood leukemia riskPopulation aged 0Site-specific countsEnd Results Program databaseCancer sitesInstitute's SurveillancePopulation-basedChildhood cancerLeukemia riskCancer diagnosisStudy designAged 0United StatesRisk factorsAverage radon levelsRRProgram databaseSexCountyPatterns of Physical Therapy Referral and Subsequent Attendance Among Childhood Cancer Survivors with Chemotherapy-Induced Peripheral Neuropathy at a Regional Childhood Cancer Survivorship Clinic
Kang L, Kadan-Lottick N, Rotatori J, Kujawski S, Messerschmidt E, Auerbach C, Balsamo L, Lustberg M, Ma X, Rodwin R. Patterns of Physical Therapy Referral and Subsequent Attendance Among Childhood Cancer Survivors with Chemotherapy-Induced Peripheral Neuropathy at a Regional Childhood Cancer Survivorship Clinic. Seminars In Oncology Nursing 2024, 40: 151716. PMID: 39164160, DOI: 10.1016/j.soncn.2024.151716.Peer-Reviewed Original ResearchChildhood cancer survivorsChemotherapy-induced peripheral neuropathyCharacteristics of survivorsPhysical therapyPercentage of adultsPT referralSurvivorship clinicCancer survivorsAttended PTPT attendanceNeighborhood characteristicsChemotherapy-induced peripheral neuropathy symptomsCancer survivorship clinicPhysical therapy referralsHigh school diplomaSurvivor educationCare coordinationOlder survivorsTherapy referralsImprove attendanceMedian percentageCancer diagnosisSchool diplomaPercentage of householdsAttendanceA Genomics-Driven Artificial Intelligence-Based Model Classifies Breast Invasive Lobular Carcinoma and Discovers CDH1 Inactivating Mechanisms.
Pareja F, Dopeso H, Wang Y, Gazzo A, Brown D, Banerjee M, Selenica P, Bernhard J, Derakhshan F, da Silva E, Colon-Cartagena L, Basili T, Marra A, Sue J, Ye Q, Da Cruz Paula A, Yeni Yildirim S, Pei X, Safonov A, Green H, Gill K, Zhu Y, Lee M, Godrich R, Casson A, Weigelt B, Riaz N, Wen H, Brogi E, Mandelker D, Hanna M, Kunz J, Rothrock B, Chandarlapaty S, Kanan C, Oakley J, Klimstra D, Fuchs T, Reis-Filho J. A Genomics-Driven Artificial Intelligence-Based Model Classifies Breast Invasive Lobular Carcinoma and Discovers CDH1 Inactivating Mechanisms. Cancer Research 2024, 84: 3478-3489. PMID: 39106449, PMCID: PMC11479818, DOI: 10.1158/0008-5472.can-24-1322.Peer-Reviewed Original ResearchConceptsInvasive lobular carcinomaBiallelic mutationsGenetic alterationsDiagnosing ILCGenotypic-phenotypic correlationsAI modelsBiological discoveryFusion geneCancer diagnosisCDH1Artificial intelligenceWhole-slide imagesInactivation mechanismLobular carcinomaMutationsHistological whole-slide imagesHistopathological featuresValidation cohortHistological featuresBreast neoplasmsHistological ground truthImprove cancer diagnosisTreatment Access among Younger Medicaid Beneficiaries with Multiple Myeloma
Fiala M, Ji M, Shih Y, Huber J, Wang M, Johnson K, Gasoyan H, Wang R, Colditz G, Wang S, Chang S. Treatment Access among Younger Medicaid Beneficiaries with Multiple Myeloma. Clinical Lymphoma Myeloma & Leukemia 2024, 25: 109-115. PMID: 39209567, DOI: 10.1016/j.clml.2024.07.017.Peer-Reviewed Original ResearchStem cell transplantationCell transplantationMyeloma therapyMultiple myelomaContinuous enrollmentAssociated with early detectionMulti-State Medicaid DatabaseMultivariate logistic regressionMyeloma patientsSolid tumorsHigh medical needMyeloma treatmentHematological cancersMyelomaPatientsMedicaid databaseClaims-based datasetScreening testAcute medical eventsLogistic regressionEarly detectionDiscontinuous enrollmentMedical needContinuous Medicaid coverageCancer diagnosisDevelopment of a Longitudinal Prostate Cancer Transcriptomic and Clinical Data Linkage
Leapman M, Ho J, Liu Y, Filson C, Zhao X, Hakansson A, Proudfoot J, Davicioni E, Martin D, An Y, Seibert T, Lin D, Spratt D, Cooperberg M, Ross A, Sprenkle P. Development of a Longitudinal Prostate Cancer Transcriptomic and Clinical Data Linkage. JAMA Network Open 2024, 7: e2417274. PMID: 38874922, PMCID: PMC11179136, DOI: 10.1001/jamanetworkopen.2024.17274.Peer-Reviewed Original ResearchConceptsElectronic health recordsCancer diagnosisClinical data linkageMedicine Clinical TermsPatterns of careProstate cancer diagnosisRadical prostatectomyCancer risk stratificationData linkageHealth recordsClinical dataMain OutcomesCancer outcomesClinical juncturesClinical careCommon Procedural Terminology codesAdministrative dataDiagnosis codesLongitudinal clinical dataCohort studyPharmacy recordsGenomic classifierProcedural Terminology codesDevelopment of prostate cancer metastasisLinkage dataPrevalence of Dietary Modification and Supplement Use in Patients with Metastatic Renal Cell Carcinoma Receiving Systemic Therapy
Ebrahimi H, Battle D, Salgia N, Zengin Z, Dizman N, Meza L, Bergerot C, Barragan-Carrillo R, Hsu J, Castro D, Mercier B, Chawla N, Li X, Tripathi A, Liu S, Chehrazi-Raffle A, Vaishampayan U, Staehler M, Pal S. Prevalence of Dietary Modification and Supplement Use in Patients with Metastatic Renal Cell Carcinoma Receiving Systemic Therapy. Nutrients 2024, 16: 1630. PMID: 38892563, PMCID: PMC11174627, DOI: 10.3390/nu16111630.Peer-Reviewed Original ResearchMetastatic renal cell carcinomaRenal cell carcinomaCell carcinomaDietary modificationSupplement useDiagnosis of renal cell carcinomaFirst-line treatmentSupplement usageSystemic therapyCombination therapyAntineoplastic therapyKetogenic dietCarcinomaCancer therapyMediterranean dietPhysician-patient dialoguePatientsTherapyCancer treatmentGrowing body of evidenceBody of evidenceDietary changesCancerCancer diagnosisCannabidiolACO leakage among gynecologic cancer patients: Incidence, predictors, and impact on annual Medicare expenditure
Osazuwa-Peters O, Greiner M, Kaufman B, Zambrano Guevara L, Dinan M, Havrilesky L, Moss H. ACO leakage among gynecologic cancer patients: Incidence, predictors, and impact on annual Medicare expenditure. Gynecologic Oncology 2024, 187: 184-191. PMID: 38788516, DOI: 10.1016/j.ygyno.2024.05.020.Peer-Reviewed Original ResearchAccountable care organizationsGynecologic cancer patientsACO sizeYear of cancer diagnosisReceipt of healthcareLog-binomial regression modelsCancer patientsNon-ACO providersPatients seeking careAdjusted risk ratiosHealth care costsAnnual Medicare expendituresMedian household incomeAssociated with useCare organizationsOutpatient careMedicare expendituresCare costsHealthcare costsMedicare spendingCancer diagnosisOutpatient settingHousehold incomeRisk ratioMultivariable adjusted risk ratios
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