2025
Portal and Hepatic Vein Embolization vs Portal Venous Embolization Alone in Cirrhotic and Non-cirrhotic Swine: A Pilot Study
Tefera J, Kuhn T, Matuschewski N, Meister E, Nguyenová J, Kao T, Mutonga M, Bitar R, Kahl V, Zhang X, Shewarega A, Chapiro J, Madoff D. Portal and Hepatic Vein Embolization vs Portal Venous Embolization Alone in Cirrhotic and Non-cirrhotic Swine: A Pilot Study. Journal Of Vascular And Interventional Radiology 2025 PMID: 40043833, DOI: 10.1016/j.jvir.2025.02.028.Peer-Reviewed Original ResearchPost-embolizationCirrhotic groupPortal venous embolizationHepatic vein embolizationPortal venous phaseNon-cirrhotic groupStudent's t-testFLR hypertrophyFLR increaseVein embolizationVenous phaseEffects of PVELiver volumeCT scanVenous embolizationEmbolizationCirrhotic liverFour-week intervalsWeeksT-testFLRLiverPilot studyYorkshire pigsPVEDetection of alteration in carotid artery volumetry using standard-of-care computed tomography surveillance scans following unilateral radiation therapy for early-stage tonsillar squamous cell carcinoma survivors: a cross-sectional internally-matched carotid isodose analysis
Koutroumpakis E, Naser M, Mohamed A, Eraj S, Jarre A, Shiao J, Kamal M, Perni S, Phan J, Morrison W, Frank S, Gunn G, Garden A, Deswal A, Abe J, Rosenthal D, Mouhayar E, Fuller C. Detection of alteration in carotid artery volumetry using standard-of-care computed tomography surveillance scans following unilateral radiation therapy for early-stage tonsillar squamous cell carcinoma survivors: a cross-sectional internally-matched carotid isodose analysis. Clinical And Translational Radiation Oncology 2025, 51: 100912. PMID: 39867727, PMCID: PMC11762641, DOI: 10.1016/j.ctro.2025.100912.Peer-Reviewed Original ResearchPost-RT CT scansCT scanTonsillar cancerPatients treated with definitive surgeryDose rangeContrast-enhanced CT scanCarotid arteryCT scans of patientsIrradiated carotid arteriesUnilateral radiation therapySignificant dose-response trendSurveillance CT scansTreated with intensityNo significant dose-response trendScans of patientsDose-response effectDose-response trendDose-response relationshipStatistically significant differenceUnilateral radiotherapyConcurrent chemoradiationInduction chemotherapyIsodose lineRadiation therapyDefinitive surgery
2024
Optimizing Automated Hematoma Expansion Classification from Baseline and Follow-Up Head Computed Tomography
Tran A, Desser D, Zeevi T, Karam G, Zietz J, Dell’Orco A, Chen M, Malhotra A, Qureshi A, Murthy S, Majidi S, Falcone G, Sheth K, Nawabi J, Payabvash S. Optimizing Automated Hematoma Expansion Classification from Baseline and Follow-Up Head Computed Tomography. Applied Sciences 2024, 15: 111. PMID: 40046237, PMCID: PMC11882137, DOI: 10.3390/app15010111.Peer-Reviewed Original ResearchIntracerebral hemorrhageHematoma expansionFollow-up CT scansFollow-up head computed tomographyPredictors of poor outcomeDeep learning classification modelFollow-up scansHead computed tomographyFalse-negative resultsHematoma segmentationAutomated segmentationMulticentre cohortCT scanValidation cohortPoor outcomeComputed tomographyFollow-upClassification modelOptimizational methodHematomaAnnotationDiagnostic performance of neural network algorithms in skull fracture detection on CT scans: a systematic review and meta-analysis
Sharifi G, Hajibeygi R, Zamani S, Easa A, Bahrami A, Eshraghi R, Moafi M, Ebrahimi M, Fathi M, Mirjafari A, Chan J, Dixe de Oliveira Santo I, Anar M, Rezaei O, Tu L. Diagnostic performance of neural network algorithms in skull fracture detection on CT scans: a systematic review and meta-analysis. Emergency Radiology 2024, 32: 97-111. PMID: 39680295, DOI: 10.1007/s10140-024-02300-7.Peer-Reviewed Original ResearchConceptsConvolutional neural networkArea under the receiver operating characteristic curveConvolutional neural network modelCT scanSkull fractureComputed tomographyDeep learningProspective clinical trialMeta-analysisReceiver operating characteristic curvePublication biasSkull fracture detectionSystematic reviewNeural network algorithmDetecting skull fracturesImprove diagnosis accuracyDiagnostic hurdlesShortage of radiologistsAutomated diagnostic toolTransfer learningDiagnostic performanceDiagnostic accuracyClinical trialsModel architectureNeural networkA Hybrid Transformer-Convolutional Neural Network for Segmentation of Intracerebral Hemorrhage and Perihematomal Edema on Non-Contrast Head Computed Tomography (CT) with Uncertainty Quantification to Improve Confidence
Tran A, Desser D, Zeevi T, Abou Karam G, Dierksen F, Dell'Orco A, Kniep H, Hanning U, Fiehler J, Zietz J, Sanelli P, Malhotra A, Duncan J, Aneja S, Falcone G, Qureshi A, Sheth K, Nawabi J, Payabvash S. A Hybrid Transformer-Convolutional Neural Network for Segmentation of Intracerebral Hemorrhage and Perihematomal Edema on Non-Contrast Head Computed Tomography (CT) with Uncertainty Quantification to Improve Confidence. Bioengineering 2024, 11: 1274. PMID: 39768092, PMCID: PMC11672977, DOI: 10.3390/bioengineering11121274.Peer-Reviewed Original ResearchNon-contrast head computed tomographyPerihematomal edemaHead computed tomographyIntracerebral hemorrhageComputed tomographyVolume similarityUniversity Medical Center Hamburg-EppendorfSecondary brain injuryYale cohortInfratentorial locationMulticentre trialCT scanTreatment planningNon-contrastHamburg-EppendorfImaging markersHemorrhagic strokeHemorrhageEdemaCohortBrain injuryDice coefficientDeep learning for oncologic treatment outcomes and endpoints evaluation from CT scans in liver cancer
Xia Y, Zhou J, Xun X, Johnston L, Wei T, Gao R, Zhang Y, Reddy B, Liu C, Kim G, Zhang J, Zhao S, Yu Z. Deep learning for oncologic treatment outcomes and endpoints evaluation from CT scans in liver cancer. Npj Precision Oncology 2024, 8: 263. PMID: 39551847, PMCID: PMC11570623, DOI: 10.1038/s41698-024-00754-z.Peer-Reviewed Original ResearchProgression-free survivalCT scanLiver cancerAccurate treatment response assessmentResponse evaluationMetastatic organ sitesOncological treatment outcomesResponse Evaluation CriteriaLow-risk patientsTreatment response assessmentTreatment response evaluationTreatment response classificationAdvanced liver cancerStratify high-riskMultifocal hepatic lesionsTreatment outcome assessmentEvaluation of responseOverall survivalEvaluation CriteriaInternal five-fold cross-validationOncology clinical trialsResponse assessmentSolid tumorsClinical trialsTreatment outcomesMOGAD presenting as fulminant intracranial hypertension
Nagaratnam S, Gill A, Jeyakumar N, Xi S, Lin M, Martin A, Varikatt W, Fong M, Morales-Briceno H. MOGAD presenting as fulminant intracranial hypertension. Journal Of Neuroimmunology 2024, 397: 578487. PMID: 39547117, DOI: 10.1016/j.jneuroim.2024.578487.Peer-Reviewed Original ResearchMyelin oligodendrocyte glycoprotein antibody diseaseSevere intracranial hypertensionIntracranial hypertensionFulminant intracranial hypertensionAbsence of demyelinationBrain CT scanManagement of intracranial pressureImmunosuppressive therapyMOG antibodiesBiopsy resultsCortical encephalitisIntensive immunotherapyAntibody diseaseBrainstem encephalitisAntibody positivityClinical improvementSurgical managementNormal MRIBrain biopsyClinical featuresCT scanDifferential diagnosisHypertensionIntracranial pressureSubcortical demyelination7029 Changes In Adrenal Gland Size Seen By Linear Assessment On Routine Abdominal CT During Critical Illness
Vangipuram D, Bhagat N, Borkar R, Mazengia N, Williams S, Majumdar S. 7029 Changes In Adrenal Gland Size Seen By Linear Assessment On Routine Abdominal CT During Critical Illness. Journal Of The Endocrine Society 2024, 8: bvae163.133. PMCID: PMC11454092, DOI: 10.1210/jendso/bvae163.133.Peer-Reviewed Original ResearchIntensive care unit admissionIntensive care unitAdrenal gland volumeAdrenal gland sizeAdrenal glandAdrenocorticotropic hormoneCritical illnessGland volumeGland sizeIncreased adrenal blood flowContrast CT scanLeft adrenal glandHypothalamus-pituitary-adrenal (HPA) axisAdrenal blood flowStatistically significant decreaseAbdominal CTRetrospective studyAdult patientsCT scanSeptic shockControl patientsPituitary glandNon-contrastCare unitVolumetric evaluationA Comparison of Machine Learning Models to Predict Lymph Node Metastasis with Primary Tumor Transcriptome in Non-Small Cell Lung Cancer
Lee V, Park H, Aneja S, Patel A. A Comparison of Machine Learning Models to Predict Lymph Node Metastasis with Primary Tumor Transcriptome in Non-Small Cell Lung Cancer. International Journal Of Radiation Oncology • Biology • Physics 2024, 120: e638. DOI: 10.1016/j.ijrobp.2024.07.1402.Peer-Reviewed Original ResearchNon-small cell lung cancerLymph nodal metastasisCell lung cancerMedian AUCNodal metastasisPrimary tumorEndobronchial ultrasoundNon-small cell lung cancer stagingLung cancerDiagnostic uncertaintyPrediction of nodal metastasisPET-avid lesionsTreatment strategy formulationPrimary lung adenocarcinomaEBUS-guided biopsiesLymph node metastasisPrimary tumor tissuesReceiver operating characteristic curveTumor transcriptomic dataPET-CTNode metastasisNeedle aspirationCT scanNon-smallClinical decision-makingSex-Specific Analysis in Patients Undergoing Talar OsteoPeriostic Grafting from the Iliac Crest (TOPIC) for Large Osteochondral Lesions of the Talus
Dahmen J, Gianakos A, Hollander J, Rikken Q, Stufkens S, Kerkhoffs G. Sex-Specific Analysis in Patients Undergoing Talar OsteoPeriostic Grafting from the Iliac Crest (TOPIC) for Large Osteochondral Lesions of the Talus. Foot & Ankle Orthopaedics 2024, 9: 2473011424s00495. PMCID: PMC11686720, DOI: 10.1177/2473011424s00495.Peer-Reviewed Original ResearchFoot and Ankle Outcome ScoreNumerical rating scaleTopical proceduresComplication rateFemale patientsClinical outcomesPre-operativelyAnkle Outcome ScoreComputed tomographyIliac crestMonths of follow-upOsteochondral lesionsSex-specific analysesProportion of womenClinically relevant improvementPre-operative sizeAssessed pre-operativelyImprovement post-operativelyStair climbingPain scoresNo significant differenceMale patientsConsecutive femalesCT scanHardware removalQuantification of Changes in Chin Morphometric Parameters Following Feminization Genioplasty
Hu K, Parikh N, Ihnat J, Flores-Pérez P, Williams M, Almeida M, Allam O, Alperovich M. Quantification of Changes in Chin Morphometric Parameters Following Feminization Genioplasty. Journal Of Craniofacial Surgery 2024, 36: 753-756. PMID: 39325150, DOI: 10.1097/scs.0000000000010688.Peer-Reviewed Original ResearchChin projectionCT scanBony changesEvaluate bony changesFACE-Q scoresFacial feminization surgeryStatistically significant decreasePatient-reported outcome measuresQuality of life patient-reported outcome measuresGenioplastyFACE-QFacial harmonyPresurgical valuesChin heightFeminization surgerySurgeryChin regionPatientsCT imagesPatient outcomesSignificant decreaseOutcome measuresChinWorld Health Organization QualityFeminismVisualization of Trochlear Dysplasia Using 3-Dimensional Curvature Analysis in Patients With Patellar Instability Facilitates Understanding and Improves the Reliability of the Entry Point to Trochlea Groove Angle
Sieberer J, Park N, Manafzadeh A, Desroches S, Brennan K, McDonald C, Tommasini S, Wiznia D, Fulkerson J. Visualization of Trochlear Dysplasia Using 3-Dimensional Curvature Analysis in Patients With Patellar Instability Facilitates Understanding and Improves the Reliability of the Entry Point to Trochlea Groove Angle. Arthroscopy Sports Medicine And Rehabilitation 2024, 7: 101010. PMID: 40041820, PMCID: PMC11873473, DOI: 10.1016/j.asmr.2024.101010.Peer-Reviewed Original ResearchPatellofemoral instability patientsInterclass correlation coefficientInterrater reliabilityPatellofemoral instabilityLevel III-retrospective cohort studyResults Qualitative analysisIII-retrospective cohort studyTrochlear grooveClinical decision-makingRetrospective cohort studyAge-sex matched controlsCohort studyMann-Whitney U testAge-sexRecurrent patellar instabilityPatient's kneeControl kneesAP viewMatched controlsKneePatellar instabilityCT scanTrochlear dysplasiaMann-WhitneyU testTrends in visits, imaging, and diagnosis for emergency department abdominal pain presentations in the United States, 2007–2019
Wu R, Adjei‐Poku M, Kelz R, Peck G, Hwang U, Cappola A, Friedman A. Trends in visits, imaging, and diagnosis for emergency department abdominal pain presentations in the United States, 2007–2019. Academic Emergency Medicine 2024, 32: 20-31. PMID: 39313946, PMCID: PMC11726162, DOI: 10.1111/acem.15017.Peer-Reviewed Original ResearchConceptsOlder adultsAbdominal painED visitsComputed tomographyNational Hospital Ambulatory Medical Care SurveyEmergency departmentCT scanTest positivityAdult ED visitsPercentage of visitsAbdominal pain presentingNationally representative dataMiddle-aged adultsAbdominal CT scanCare SurveyPain presentationsAge-specificIncrease imaging ratesPractice patternsSurgical diagnosisAbdominal imagingDiagnostic pathwayRepresentative dataAcute pathologyVisitsCT-based multimodal deep learning for non-invasive overall survival prediction in advanced hepatocellular carcinoma patients treated with immunotherapy
Xia Y, Zhou J, Xun X, Zhang J, Wei T, Gao R, Reddy B, Liu C, Kim G, Yu Z. CT-based multimodal deep learning for non-invasive overall survival prediction in advanced hepatocellular carcinoma patients treated with immunotherapy. Insights Into Imaging 2024, 15: 214. PMID: 39186192, PMCID: PMC11347550, DOI: 10.1186/s13244-024-01784-8.Peer-Reviewed Original ResearchConvolutional-recurrent neural networkAdvanced hepatocellular carcinomaSpatial-temporal informationHepatocellular carcinomaCT scanOverall survival predictionRECIST criteriaClinical variablesPatients treated with immunotherapyExtract spatial-temporal informationFollow-up CT imagesPrognostic modelAdvanced HCC patientsRisk group stratificationDeep learning-based modelTest setDisease statusMethodsThis retrospective studyLog-rank testMultimodal deep learningMulti-modal inputsSurvival predictionDeep learning modelsAnalysis of CT scansPatient's disease statusCochlear Apex Triangulation Utilizing Ct Measures And Middle Ear Landmarks
Cottrell J, Landsberger D, Breen M, Lebowitz J, Hagiwara M, Moonis G, Shapiro W, Friedmann D, Jethanamest D, McMenomey S, Roland J. Cochlear Apex Triangulation Utilizing Ct Measures And Middle Ear Landmarks. Otology & Neurotology Open 2024, 4: e060-e060. PMID: 39328867, PMCID: PMC11424059, DOI: 10.1097/ono.0000000000000060.Peer-Reviewed Original ResearchCochlear apexRound windowCochlear implant recipientsCochleariform processTemporal bone CT scansComputed tomographyMiddle ear landmarksImplant recipientsPreoperative computed tomographyTertiary referral centerSurgically relevant landmarksSuperior-inferior distanceImprove procedural successReferral centerSurgical approachCT scanOval windowAnteroposterior distanceMultiplanar reformattingCT measurementsCritical structuresReduce traumaSurrounding structuresPromontory boneElectrode placementLetter to the Editor: “Silent myocardial infarction fatty scars detected by coronary calcium score CT scan in diabetic patients without a history of coronary heart disease”
Bader A, Haramati L. Letter to the Editor: “Silent myocardial infarction fatty scars detected by coronary calcium score CT scan in diabetic patients without a history of coronary heart disease”. European Radiology 2024, 35: 215-217. PMID: 38995379, DOI: 10.1007/s00330-024-10912-3.Peer-Reviewed Original ResearchDeep learning survival model predicts outcome after intracerebral hemorrhage from initial CT scan
Chen Y, Rivier C, Mora S, Lopez V, Payabvash S, Sheth K, Harloff A, Falcone G, Rosand J, Mayerhofer E, Anderson C. Deep learning survival model predicts outcome after intracerebral hemorrhage from initial CT scan. European Stroke Journal 2024, 10: 225-235. PMID: 38880882, PMCID: PMC11569453, DOI: 10.1177/23969873241260154.Peer-Reviewed Original ResearchIntracerebral hemorrhage scoreNon-contrast CT scanIntracerebral hemorrhageCT scanFUNC scoreIntracerebral hemorrhage patientsNon-contrast CTFunctional impairmentSevere disabilityDependent living statusLong-term functional impairmentC-indexPrognostic toolFunctional outcomesTreatment decisionsAcute settingClinical implementationRehabilitation strategiesDependent livingPatientsPredicting functional impairmentLong-term care needsPlanning of patient careDeep learning modelsHemorrhageUnderstanding the Added Value of High-Resolution CT Beyond Chest X-Ray in Determining Extent of Physiologic Impairment
Benn B, Lippitt W, Cortopassi I, Balasubramani G, Barbosa E, Drake W, Herzog E, Gibson K, Chen E, Koth L, Fuhrman C, Lynch D, Kaminski N, Wisniewski S, Carlson N, Maier L. Understanding the Added Value of High-Resolution CT Beyond Chest X-Ray in Determining Extent of Physiologic Impairment. CHEST Journal 2024, 166: 1093-1107. PMID: 38830401, PMCID: PMC11560486, DOI: 10.1016/j.chest.2024.04.031.Peer-Reviewed Original ResearchScadding stageCT featuresLung functionChest radiologistsCT scanAlpha-1 anti-trypsin deficiencyChest computed tomographyChest CT scanChest X-rayIncreasing clinical useCompare demographic featuresAssociated with FEV1Visual scoring systemSarcoidosis stagePulmonary sarcoidosisChest CTCT findingsAssociated with lung functionCT assessmentComputed tomographySarcoidosisClinical useRadiological measurementsCT measurementsScoring systemLymph node metastasis prediction with non-small cell lung cancer histopathology imaging.
Lee V, King A, Sritharan D, Moore N, Chadha S, Maresca R, Hager T, Aneja S. Lymph node metastasis prediction with non-small cell lung cancer histopathology imaging. Journal Of Clinical Oncology 2024, 42: 8063-8063. DOI: 10.1200/jco.2024.42.16_suppl.8063.Peer-Reviewed Original ResearchNon-small cell lung cancerLymph nodal metastasisNational Lung Screening TrialLymph node metastasisNodal metastasisNode metastasisEndobronchial ultrasound-guided transbronchial needle aspirationUltrasound-guided transbronchial needle aspirationTreatment strategy formulationTransbronchial needle aspirationCell lung cancerDistant metastasis statusLymph node metastasis predictionPrimary tumor dataHematoxylin and eosin (H&EInvasive diagnostic techniquesInfluence clinical decisionsN0 diseaseN3 diseaseEosin (H&EPrimary resectionDistant metastasisPET-CTNeedle aspirationCT scanThe Morphologic Patella Entry Point Into the Proximal Trochlea Is More Lateral in Recurrent Dislocators Than Controls as Measured by Entry Point–Trochlear Groove Angle
Beitler B, Sieberer J, Islam W, McDonald C, Yu K, Tommasini S, Fulkerson J. The Morphologic Patella Entry Point Into the Proximal Trochlea Is More Lateral in Recurrent Dislocators Than Controls as Measured by Entry Point–Trochlear Groove Angle. Arthroscopy The Journal Of Arthroscopic And Related Surgery 2024, 41: 703-712. PMID: 38697328, DOI: 10.1016/j.arthro.2024.04.013.Peer-Reviewed Original ResearchRecurrent patella instabilityPatella instabilityLevel III-case-control studyRecurrent dislocationRecurrent dislocation groupMann-Whitney U testCase-control studyRecurrent patella dislocationIntraclass correlation coefficientDistal femurCT scanOptimal treatmentProximal trochleaPatellar dislocationU testControlled studiesInclusion criteriaPatella dislocationSenior authorRight kneeKnee pathologyControl groupSimpleware ScanIPBayesian mixed effects modelsAP images
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