2025
A Prospective Study of Conventionally Fractionated Dose Constraints for Reirradiation of Primary Brain Tumors in Children
McGovern S, Johnson J, Luo D, Nguyen K, McAleer M, Paulino A, Grosshans D, Baxter P, Zaky W, Thall P, Mahajan A. A Prospective Study of Conventionally Fractionated Dose Constraints for Reirradiation of Primary Brain Tumors in Children. International Journal Of Radiation Oncology • Biology • Physics 2025, 121: e13-e14. DOI: 10.1016/j.ijrobp.2024.11.049.Peer-Reviewed Original ResearchDose-volume constraintsSymptomatic brain necrosisRecurrent brain tumorsBrain tumorsBrain necrosisPrimary endpointDose constraintsProton therapyProspective studyRecurrent pediatric brain tumorsMedian overall survivalMedian prescription doseCourse of radiationResults Median ageTreated with radiationPediatric brain tumorsPrimary brain tumorProgression of diseaseBrain reirradiationDosimetric guidelinesDose escalationPrescription doseOverall survivalMedian intervalProspective trials
2020
Temporal Lobe Necrosis in Head and Neck Cancer Patients after Proton Therapy to the Skull Base
Kitpanit S, Lee A, Pitter KL, Fan D, Chow JCH, Neal B, Han Z, Fox P, Sine K, Mah D, Dunn LA, Sherman EJ, Michel L, Ganly I, Wong RJ, Boyle JO, Cohen MA, Singh B, Brennan CW, Gavrilovic IT, Hatzoglou V, O'Malley B, Zakeri K, Yu Y, Chen L, Gelblum DY, Kang JJ, McBride SM, Tsai CJ, Riaz N, Lee NY. Temporal Lobe Necrosis in Head and Neck Cancer Patients after Proton Therapy to the Skull Base. International Journal Of Particle Therapy 2020, 6: 17-28. PMID: 32582816, PMCID: PMC7302730, DOI: 10.14338/ijpt-20-00014.1.Peer-Reviewed Original ResearchMagnetic resonance imagingRadiation-naïve patientsDose-volume parametersSkull baseNeck cancerTemporal lobeCutoff valueMaximum doseProton therapyAdverse Events v5.0Common Terminology CriteriaTemporal lobe necrosisNeck cancer patientsDose-volume factorsTerminology CriteriaMedian followBrain necrosisMedian timeClinical parametersCancer patientsMedical recordsGrade 3Necrosis rateField of radiationPatients
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