2023
Novel Standalone Motion-Sparing Pelvic Fixation Prevents Short-Term Insufficiency Fractures After Midsacrectomies Without Sacrificing Normal, Mobile Lumbar Segments Traditionally Used for Stabilization
Lo S, Pieters T, Hersh A, Green R, Suk I, Pennington Z, Elsamadicy A, Sciubba D. Novel Standalone Motion-Sparing Pelvic Fixation Prevents Short-Term Insufficiency Fractures After Midsacrectomies Without Sacrificing Normal, Mobile Lumbar Segments Traditionally Used for Stabilization. Operative Neurosurgery 2023, 25: 278-284. PMID: 37278692, DOI: 10.1227/ons.0000000000000767.Peer-Reviewed Original ResearchConceptsSacral insufficiency fracturesMobile lumbar segmentsInsufficiency fracturesPelvic fixationPartial sacrectomyLumbar segmentsMedian age 59 yearsPrimary malignant bone tumorAge 59 yearsTreatment of choiceMalignant bone tumorsComprehensive cancer centerRetrospective data setConcomitant placementAdverse eventsOverall survivalPrimary outcomeSacral tumorsHistorical cohortMobile spineRetrospective studyCancer CenterLumbopelvic fixationOperative characteristicsBone tumorsSecond Primary Malignancies of the Bones and Joints: More Common than Expected in Osteosarcoma Patients
Freedman I, Dowd H, Dhodapkar M, Halperin S, Grauer J. Second Primary Malignancies of the Bones and Joints: More Common than Expected in Osteosarcoma Patients. JAAOS Global Research And Reviews 2023, 7: e22.00275. PMID: 36695170, PMCID: PMC9875998, DOI: 10.5435/jaaosglobal-d-22-00275.Peer-Reviewed Original ResearchConceptsSecond primary malignanciesStandardized incidence ratiosOsteosarcoma survivorsPrimary malignancyCommon second primary malignancyNational Cancer Institute's SurveillanceEnd Results 18 databaseCommon primary bone tumorPrimary bone tumorsPopulation-level dataIncidence ratiosOverall incidenceOsteosarcoma patientsPatient populationExcess riskBone tumorsAnatomic locationLong-term eventsOsteosarcoma casesPatientsYoung adultsTumorsSoft tissueMalignancyOsteosarcomaUpdate of pediatric bone tumors—other mesenchymal tumors of bone, hematopoietic neoplasms of bone, and WHO classification of undifferentiated small round cell sarcomas of bone
Wang A, Maloney E, Al-Dasuqi K, Irshaid L, Ahmed A, Haims A, Porrino J. Update of pediatric bone tumors—other mesenchymal tumors of bone, hematopoietic neoplasms of bone, and WHO classification of undifferentiated small round cell sarcomas of bone. Skeletal Radiology 2023, 52: 1443-1463. PMID: 36656343, DOI: 10.1007/s00256-023-04286-8.Peer-Reviewed Original ResearchConceptsUndifferentiated small round cell sarcomaSmall round cell sarcomasBone tumorsRound cell sarcomasPediatric populationCell sarcomaMesenchymal tumorsHematopoietic neoplasmsWorld Health Organization classificationGiant cell-rich tumorsPediatric bone tumorsOsteogenic tumorsOrganization classificationVascular tumorsNotochordal tumorsTumorsGenetic sequencing techniquesChondrogenic tumorsCertain lesionsSoft tissueBoneSarcomaNeoplasmsSeparate manuscriptDetailed update
2022
Update of pediatric bone tumors—notochordal tumors, chondrogenic tumors, and vascular tumors of the bone
Lee H, Wang A, Cheng R, Moran J, Al-Dasuqi K, Irshaid L, Maloney E, Porrino J. Update of pediatric bone tumors—notochordal tumors, chondrogenic tumors, and vascular tumors of the bone. Skeletal Radiology 2022, 52: 1101-1117. PMID: 36369290, DOI: 10.1007/s00256-022-04235-x.Peer-Reviewed Original ResearchUpdate of pediatric bone tumors: osteogenic tumors and osteoclastic giant cell-rich tumors
Al-Dasuqi K, Cheng R, Moran J, Irshaid L, Maloney E, Porrino J. Update of pediatric bone tumors: osteogenic tumors and osteoclastic giant cell-rich tumors. Skeletal Radiology 2022, 52: 671-685. PMID: 36326880, DOI: 10.1007/s00256-022-04221-3.Peer-Reviewed Original ResearchChapter 61 Neuroimaging for surgical treatment planning of neoplastic disease of the spine
Goulart C, Elsamadicy A, Mattei T, Reeves B, Weicker M, Johnson M, Mendel E. Chapter 61 Neuroimaging for surgical treatment planning of neoplastic disease of the spine. 2022, 871-891. DOI: 10.1016/b978-0-12-822835-7.00068-8.Peer-Reviewed Original ResearchMagnetic resonance imagingNew-onset low back painContrasted magnetic resonance imagingSpinal cord compressionExtent of diseaseEn bloc resectionLow back painPrimary bone tumorsComputed tomography scanImaging-guided biopsySurgical intervention procedureSurgical treatment planningSpinal cancerCord compressionNeck painPreoperative embolisationBone involvementIntraoperative bleedingIntramedullary lesionBloc resectionIntradural tumorsVertebral arteryBone tumorsTomography scanLikely diagnosis
2019
Benign Bone Tumors about the Hip
Patel J, Gianakos A, Miller J, Hoskins T, Wittig J. Benign Bone Tumors about the Hip. The Journal Of Hip Surgery 2019, 03: 008-013. DOI: 10.1055/s-0039-1678741.Peer-Reviewed Original Research
2016
Giant Cell Tumor with Secondary Aneurysmal Bone Cyst Shows Heterogeneous Metabolic Pattern on 18F-FDG PET/CT: A Case Report
Park H, Kwon S, Cho S, Kim J, Song H, Kim S, Yoon Y, Park J. Giant Cell Tumor with Secondary Aneurysmal Bone Cyst Shows Heterogeneous Metabolic Pattern on 18F-FDG PET/CT: A Case Report. Nuclear Medicine And Molecular Imaging 2016, 50: 348-352. PMID: 27994691, PMCID: PMC5135695, DOI: 10.1007/s13139-016-0423-z.Peer-Reviewed Original ResearchSecondary aneurysmal bone cystGiant cell tumorAneurysmal bone cystCystic componentCell tumorsMaximum standardized uptake valuePositron emission tomography/computed tomographyBone cystCase of giant cell tumorEmission tomography/computed tomographyStandardized uptake valueAneurysmal bone cyst componentMetabolic patternsBenign bone tumorsLeft proximal femurPrimary bone neoplasmsHypermetabolic lesionsTomography/computed tomographyFluorodeoxyglucose uptakeUptake valueCase reportPET/CTBone neoplasmsBone tumorsBenign nature
2014
Genetic alterations in chondrosarcomas – keys to targeted therapies?
Samuel AM, Costa J, Lindskog DM. Genetic alterations in chondrosarcomas – keys to targeted therapies? Cellular Oncology 2014, 37: 95-105. PMID: 24458248, DOI: 10.1007/s13402-014-0166-8.Peer-Reviewed Original ResearchConceptsBenign cartilaginous lesionsCartilaginous lesionsMalignant transformationIhh/PTHrPTwo-hit scenarioPrimary bone tumorsGenetic alterationsDruggable molecular targetsKey genetic alterationsHuman tumor typesResultsCurrent dataBone tumorsMalignant tumorsSarcoma typesMalignant chondrosarcomasKey molecular changesNormal cell cycle controlTumor typesMalignant cellsChondrosarcoma developmentLesionsMolecular targetsTumorsEarly-stage eventsDifferentiation of chondrocytes
2010
Management of a parturient with high-grade osteosarcoma of the proximal femur: a multidisciplinary approach
Quaye A, Raskin K, Ecker J, Leffert L. Management of a parturient with high-grade osteosarcoma of the proximal femur: a multidisciplinary approach. International Journal Of Obstetric Anesthesia 2010, 19: 340-342. PMID: 20627530, DOI: 10.1016/j.ijoa.2010.03.013.Peer-Reviewed Original ResearchConceptsHigh-grade osteosarcomaCommon primary malignant bone tumorPrimary malignant bone tumorWeeks of gestationMalignant bone tumorsNewborn baby boyFemoral neck resectionAdjuvant chemotherapyCesarean deliveryMultiparous womenPathologic fractureSpinal anesthesiaSubsequent surgeryLimb salvageThird trimesterOncologic therapyBone tumorsMultidisciplinary planningNeck resectionBaby boyProximal femurOsteosarcomaMultidisciplinary approachPregnancyMothers
2006
Quantitative in Situ Assessment of the Somatostatin Receptor in Breast Cancer to Assess Response to Targeted Therapy With 111-in-Penetreotide
Chung G, Murren J, Rimm D. Quantitative in Situ Assessment of the Somatostatin Receptor in Breast Cancer to Assess Response to Targeted Therapy With 111-in-Penetreotide. 2006 DOI: 10.21236/ada455786.Peer-Reviewed Original ResearchBreast cancerTissue microarrayPredominant receptor subtypeBenign breast tissueSSTR2 levelsProgression of cancerSSTR2 expressionBone tumorsTargeted therapyReceptor subtypesSomatostatin receptorsClinical significanceCo-localization techniquesCell line controlMalignant cellsCancerBreast tissuePattern of expressionProtein expressionPeptide hormonesSomatostatinSSTR2ExpressionLarge proportionTherapy
2004
Treatment of allograft nonunions with recombinant human bone morphogenetic proteins (rhBMP).
Delloye C, Suratwala SJ, Cornu O, Lee FY. Treatment of allograft nonunions with recombinant human bone morphogenetic proteins (rhBMP). Acta Orthopaedica Belgica 2004, 70: 591-7. PMID: 15669462.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBone Morphogenetic ProteinsBone NeoplasmsBone TransplantationFemaleFollow-Up StudiesFractures, UnunitedHumansMaleMiddle AgedOsteosarcomaRadiographyRetrospective StudiesRisk AssessmentSampling StudiesSarcoma, EwingSensitivity and SpecificityTransplantation, HomologousTreatment OutcomeConceptsAllograft-host junctionAllograft nonunionRecombinant human bone morphogenetic proteinAllograft fractureIntercalary allograftsFracture nonunionHuman bone morphogenetic proteinAdditional radiation therapyMalignant bone tumorsRhBMP-7Allograft bone transplantationBone morphogenetic proteinAdjuvant chemotherapySterile drainageRadiological evidenceCorticocancellous allograftFemoral allograftsTibial nonunionWide resectionOsteoarticular allograftsTumor recurrenceMain complicationsNonunion siteBone tumorsRadiation therapy
2003
Malignant bone tumors: limb sparing versus amputation.
DiCaprio MR, Friedlaender GE. Malignant bone tumors: limb sparing versus amputation. Journal Of The American Academy Of Orthopaedic Surgeons 2003, 11: 25-37. PMID: 12699369, DOI: 10.5435/00124635-200301000-00005.Peer-Reviewed Original ResearchConceptsLimb-sparing proceduresAppropriate surgical alternativesFunctional outcome studiesMainstay of treatmentExtent of diseaseAllograft-prosthetic compositeMalignant bone tumorsImportant outcome measureEffective chemotherapeutic agentLimb sparingMost patientsPatient ageReconstructed limbExpandable prosthesisSurgical alternativeTumor locationBone tumorsReconstructive surgeryOutcome measuresOutcome studiesSatisfactory functionModular endoprosthesesSurvival rateBone graftChemotherapeutic agents
1984
Transplantation of Osteochondral Allografts
Friedlaender G, Mankin H. Transplantation of Osteochondral Allografts. Annual Review Of Medicine 1984, 35: 311-324. PMID: 6372659, DOI: 10.1146/annurev.me.35.020184.001523.Peer-Reviewed Original ResearchConceptsOsteochondral allograftsMassive osteochondral allograftsExcellent clinical resultsLimb-sparing approachesClinical resultsSkeletal deficitsBone tumorsImmune responseNeoplastic disordersCartilage graftsAllograftsSatisfactory tissueGraftEffective boneTransplantationLesionsTumorsInfectionAntigenBiological significance
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply