2025
Personalizing core decompression grafting technique for osteonecrosis of the femoral head: calculating the volume of bone resected and adjunct volume required to fill the defect
Bergemann R, Massey A, Tommasini S, Wiznia D. Personalizing core decompression grafting technique for osteonecrosis of the femoral head: calculating the volume of bone resected and adjunct volume required to fill the defect. Journal Of Orthopaedic Surgery And Research 2025, 20: 229. PMID: 40033401, PMCID: PMC11874654, DOI: 10.1186/s13018-025-05606-5.Peer-Reviewed Original ResearchConceptsAdjunctive therapyVolume of boneCore decompressionBone marrow aspirate concentrateRisk of complicationsFemoral headSynthetic bone substituteAmount of boneBone substituteAspirate concentrateExpandable reamerBone regenerationBone graftPrevent collapseDebilitating diseaseReamer systemBoneAdjunctGrafting techniqueDecompression
2024
Using Computed Tomography-Based Three-dimensional Modeling and Computer Navigation for Minimally Invasive Core Decompression and Adjuvant Orthobiologic Therapy of Femoral Head Avascular Necrosis
Feizi A, Bell C, Roytman G, Park N, Wang A, Tommasini S, Wiznia D. Using Computed Tomography-Based Three-dimensional Modeling and Computer Navigation for Minimally Invasive Core Decompression and Adjuvant Orthobiologic Therapy of Femoral Head Avascular Necrosis. Arthroplasty Today 2024, 26: 101337. PMID: 38497084, PMCID: PMC10940782, DOI: 10.1016/j.artd.2024.101337.Peer-Reviewed Original ResearchFemoral head avascular necrosisAvascular necrosisSurgical techniqueCore decompressionBone marrow aspirate concentrateDelay disease progressionOutcome of core decompressionAdjuvant therapyCellular therapyAspirate concentrateDisease progressionFemoral head collapseImprove outcomesLesionsDebilitating conditionTherapyComputer navigationNecrosisDecompressionHead collapseThree-dimensional modelFemoral head
2016
Bone Marrow Aspirate Concentrate in Animal Long Bone Healing
Gianakos A, Ni A, Zambrana L, Kennedy J, Lane J. Bone Marrow Aspirate Concentrate in Animal Long Bone Healing. Journal Of Orthopaedic Trauma 2016, 30: 1-9. PMID: 26371620, DOI: 10.1097/bot.0000000000000453.Peer-Reviewed Original ResearchConceptsBone marrow aspirate concentrateBone healingLong bone healingBone mesenchymal stem cellsUse of BMACConfer beneficial effectsLong bone fracturesPubMed/MEDLINESegmental defectsSignificant increaseEarly bone healingBMAC groupEmbase databasesComputed tomographyBone fracturesHistomorphometric assessmentMesenchymal stem cellsBone areaBeneficial effectsVivo evidenceBone formationVivo studiesLong bonesConfidence intervalsHealing
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