2025
Decline in Community-Acquired Alveolar Pneumonia Positive for Respiratory Syncytial Virus in Hospitalized Children Following Implementation of Pneumococcal Conjugate Vaccine (PCV) in Israel
Dagan R, van der Beek B, Grupel T, Greenberg D, Keren-Naus A, Ben-Shimol S, Weinberger D. Decline in Community-Acquired Alveolar Pneumonia Positive for Respiratory Syncytial Virus in Hospitalized Children Following Implementation of Pneumococcal Conjugate Vaccine (PCV) in Israel. Clinical Infectious Diseases 2025, ciaf102. PMID: 40052957, DOI: 10.1093/cid/ciaf102.Peer-Reviewed Original ResearchPneumococcal conjugate vaccineImpact of pneumococcal conjugate vaccinesConjugate vaccineCommunity-acquired alveolar pneumoniaPneumococcal conjugate vaccine implementationImplementation of pneumococcal conjugate vaccinesRespiratory syncytial virusAnnual hospitalization rateCommunity-acquiredAlveolar pneumoniaSyncytial virusPCV13 implementationAnnual incidenceYoung childrenHospitalization ratesIncidenceRSVMonthsVaccineChildrenEpisodesRegression modelsSynergistic rolePCV13Binomial regression modelsTransient Ischemic Attack in Women: Real-World Hospitalization Incidence, Outcomes, and Risk of Hemorrhage and Stroke
Chen H, Khunte M, Colasurdo M, Majmundar S, Payabvash S, Chaturvedi S, Malhotra A, Gandhi D. Transient Ischemic Attack in Women: Real-World Hospitalization Incidence, Outcomes, and Risk of Hemorrhage and Stroke. Stroke 2025, 56: 285-293. PMID: 39869710, DOI: 10.1161/strokeaha.124.049278.Peer-Reviewed Original ResearchConceptsRates of vascular risk factorsTransient ischemic attackUS Census Bureau dataAssociated with lower oddsHigher odds of deathIschemic strokeRisk factorsAnnual incidenceTransient neurological symptomsStroke risk factorsOdds of deathLogistic regression modelsVascular risk factorsCensus Bureau dataRate of headacheRetrospective cohort studyLower oddsHigher oddsNeurological symptomsHome dischargeCohort studyIschemic attackHospital incidenceExcess hospitalizationsRisk of hemorrhageA comprehensive analysis of serotype-specific invasive capacity, clinical presentations, and mortality trends of invasive pneumococcal disease
Yildirim M, Keskinocak P, Hinderstein S, Tran K, Dasthagirisaheb Y, Madoff L, Pelton S, Yildirim I. A comprehensive analysis of serotype-specific invasive capacity, clinical presentations, and mortality trends of invasive pneumococcal disease. Vaccine 2025, 47: 126692. PMID: 39778476, DOI: 10.1016/j.vaccine.2024.126692.Peer-Reviewed Original ResearchConceptsInvasive pneumococcal diseasePneumococcal conjugate vaccineClinical presentationInvasive diseasePneumococcal diseaseAnnual incidence of invasive pneumococcal diseaseIncidence of invasive pneumococcal diseaseInvasive capacityInvasive pneumococcal disease serotypesPost-PCV13 eraReduced invasive diseasePneumococcal nasopharyngeal colonizationYears of ageNP carriageSerotype 35BPost-PCV13Respiratory seasonsCarriage prevalenceNasopharyngeal colonizationStreptococcus pneumoniaeConjugate vaccineSerotype 18CAnnual incidenceVaccination strategiesNP isolates
2024
Perioperative inpatient falls for anterior cervical discectomy and fusion patients are on the rise: Risk factors associated with this “never event”
Seddio A, Jabbouri S, Gouzoulis M, Vasudevan R, Halperin S, Varthi A, Rubio D, Grauer J. Perioperative inpatient falls for anterior cervical discectomy and fusion patients are on the rise: Risk factors associated with this “never event”. The Spine Journal 2024 PMID: 39631462, DOI: 10.1016/j.spinee.2024.11.018.Peer-Reviewed Original ResearchInpatient fallsLength of stayMultivariate logistic regressionAnterior cervical discectomyInpatient ACDFElixhauser Comorbidity IndexMultidisciplinary fall prevention programAnnual incidenceRisk factorsInpatient fall preventionFall prevention programsLogistic regressionNational sample of patientsCervical discectomyNational Quality ForumSocioeconomically disadvantaged patientsHistory of dementiaUnderweight body mass indexACDF patientsObese BMI >Posterior cervical proceduresBody mass indexMulti-level ACDFAdult patientsQuality ForumHepatitis B
Khungar V, Han T. Hepatitis B. 2024, 227-235. DOI: 10.1201/9781003524489-36.Peer-Reviewed Original Research
2023
Epidemiologic trends of domestic violence–related ocular injuries among pediatric patients: data from the Nationwide Emergency Department Sample 2008-2017
Andoh J, Miguez S, Andoh S, Mehta S, Mir T, Chen E, Jain S, Teng C, Nwanyanwu K. Epidemiologic trends of domestic violence–related ocular injuries among pediatric patients: data from the Nationwide Emergency Department Sample 2008-2017. Journal Of American Association For Pediatric Ophthalmology And Strabismus 2023, 27: 335.e1-335.e8. PMID: 37931837, PMCID: PMC10859911, DOI: 10.1016/j.jaapos.2023.09.008.Peer-Reviewed Original ResearchConceptsOcular injuriesHospital stayED encountersMedian chargePediatric emergency department patientsCommon ocular diagnosisEye/adnexaMedian hospital stayEmergency department patientsMechanism of injuryInpatient hospital stayCross-sectional studyLow socioeconomic statusLowest income quartileSpecific social determinantsPediatric patientsAnnual incidenceDepartment patientsMedicaid insuranceMedian lengthTrauma hospitalSecondary diagnosisOcular diagnosisEpidemiologic trendsPatientsResistance-minimising strategies for introducing a novel antibiotic for gonorrhoea treatment: a mathematical modelling study
Reichert E, Yaesoubi R, Rönn M, Gift T, Salomon J, Grad Y. Resistance-minimising strategies for introducing a novel antibiotic for gonorrhoea treatment: a mathematical modelling study. The Lancet Microbe 2023, 4: e781-e789. PMID: 37619582, PMCID: PMC10865326, DOI: 10.1016/s2666-5247(23)00145-3.Peer-Reviewed Original ResearchConceptsPrevalence of resistancePrimary outcomeGonococcal infectionGonorrhea treatmentCombination therapyAntibiotic resistanceResistance emergenceNew antibioticsNew drugsUrgent public health concernCombination therapy strategiesSexual activity groupsPopulation-level prevalencePublic health concernSecondary outcomesAnnual incidenceGonorrhoea transmissionCurrent therapiesMSM populationUS CentersMathematical modelling studyCurrent drugsUS populationNeisseria gonorrhoeaeInfectious diseasesThe Burden of Revision Total Ankle Replacement Has Increased From 2010 to 2020
Ratnasamy P, Maloy G, Oghenesume O, Peden S, Grauer J, Oh I. The Burden of Revision Total Ankle Replacement Has Increased From 2010 to 2020. Foot & Ankle Orthopaedics 2023, 8: 24730114231198234. PMID: 37767009, PMCID: PMC10521287, DOI: 10.1177/24730114231198234.Peer-Reviewed Original ResearchElixhauser Comorbidity IndexHigher Elixhauser comorbidity indexRetrospective cohort studyCohort studyIndependent predictorsAnnual incidenceRevision surgeryRisk factorsYounger ageMultivariate logistic regression analysisRevision total ankle replacementTotal ankle replacement surgeryIndependent risk factorImplant survival rateTiming of revisionLogistic regression analysisSite of careTotal ankle replacementAnkle replacement surgeryExplant patientsExplant surgeryComorbidity indexPatient factorsIndex procedureFemale sexPreliminary Incidence and Trends of Infections Caused by Pathogens Transmitted Commonly Through Food — Foodborne Diseases Active Surveillance Network, 10 U.S. Sites, 2022
Delahoy M, Shah H, Weller D, Ray L, Smith K, McGuire S, Trevejo R, Walter E, Wymore K, Rissman T, McMillian M, Lathrop S, LaClair B, Boyle M, Harris S, Zablotsky-Kufel J, Houck K, Devine C, Lau C, Tauxe R, Bruce B, Griffin P, Payne D. Preliminary Incidence and Trends of Infections Caused by Pathogens Transmitted Commonly Through Food — Foodborne Diseases Active Surveillance Network, 10 U.S. Sites, 2022. MMWR Morbidity And Mortality Weekly Report 2023, 72: 701-706. PMID: 37384552, PMCID: PMC10328488, DOI: 10.15585/mmwr.mm7226a1.Peer-Reviewed Original ResearchConceptsAverage annual incidenceActive Surveillance NetworkShiga toxin-producing Escherichia coliAnnual incidenceEnteric infectionsFood — Foodborne Diseases Active Surveillance NetworkFoodborne Diseases Active Surveillance NetworkLaboratory-diagnosed infectionsToxin-producing Escherichia coliPublic health interventionsTrend of infectionSurveillance networkPreliminary IncidenceMajor foodborne pathogenHealth interventionsInfectionIncidenceIllnessBehavioral modificationCOVID-19 pandemicU.S. sitesInternational travelPandemic interventionsInterventionFoodborne pathogens
2022
Comparing the Epidemiology and Health Burden of Lyme Disease and Babesiosis Hospitalizations in the United States
Bloch E, Zhu X, Krause P, Patel E, Grabowski M, Goel R, Auwaerter P, Tobian A. Comparing the Epidemiology and Health Burden of Lyme Disease and Babesiosis Hospitalizations in the United States. Open Forum Infectious Diseases 2022, 9: ofac597. PMID: 36467296, PMCID: PMC9709699, DOI: 10.1093/ofid/ofac597.Peer-Reviewed Original ResearchNational Inpatient SampleLyme diseaseMale patientsAnnual incidenceHealth burdenLonger hospital stayMean hospital chargesHigher inpatient costsHospital-level variablesStratified systematic random sampleUS Census Bureau dataPerson/yearHospital stayPatient demographicsHospital admissionClinical outcomesHospital chargesInpatient costsInpatient hospitalizationInpatient SampleAdmission costsHospitalizationUS hospitalsDisease severitySystematic random sampleFrequency, Demographics, Comorbidities, and Health Care Utilization by Veterans With Migraine
Seng EK, Fenton BT, Wang K, Lipton RB, Ney J, Damush T, Grinberg AS, Skanderson M, Sico JJ. Frequency, Demographics, Comorbidities, and Health Care Utilization by Veterans With Migraine. Neurology 2022, 99: e1979-e1992. PMID: 36100439, PMCID: PMC9651466, DOI: 10.1212/wnl.0000000000200888.Peer-Reviewed Original ResearchConceptsVeterans Health AdministrationHealth care utilizationStudy periodCare utilizationHealth AdministrationOne-year period prevalenceOverweight/obesityMental health disordersChi-square testStudent's t-testMilitary sexual traumaAnnual encountersHeadache comorbidityPain comorbiditiesCohort entryCommon comorbiditiesPain disordersTotal cohortAnnual incidenceHealthcare utilizationHigher proportionPeriod prevalenceEmergency departmentMigraine carePrimary carePreliminary Incidence and Trends of Infections Caused by Pathogens Transmitted Commonly Through Food — Foodborne Diseases Active Surveillance Network, 10 U.S. Sites, 2016–2021
Collins J, Shah H, Weller D, Ray L, Smith K, McGuire S, Trevejo R, Jervis R, Vugia D, Rissman T, Garman K, Lathrop S, LaClair B, Boyle M, Harris S, Kufel J, Tauxe R, Bruce B, Rose E, Griffin P, Payne D. Preliminary Incidence and Trends of Infections Caused by Pathogens Transmitted Commonly Through Food — Foodborne Diseases Active Surveillance Network, 10 U.S. Sites, 2016–2021. MMWR Morbidity And Mortality Weekly Report 2022, 71: 1260-1264. PMID: 36201372, PMCID: PMC9541031, DOI: 10.15585/mmwr.mm7140a2.Peer-Reviewed Original ResearchConceptsHealthy People 2030 goalIncidence of infectionActive Surveillance NetworkShiga toxin-producing Escherichia coliAnnual incidenceEnteric infectionsFood — Foodborne Diseases Active Surveillance NetworkFoodborne Diseases Active Surveillance NetworkActive population-based surveillanceLaboratory-diagnosed infectionsPopulation-based surveillanceAverage annual incidenceToxin-producing Escherichia coliPublic health interventionsTrend of infectionSurveillance networkPreliminary IncidenceCampylobacter infectionSalmonella infectionHealth interventionsInfectionIncidenceBehavioral modificationCOVID-19 pandemicU.S. sitesRainfall and other meteorological factors as drivers of urban transmission of leptospirosis
Cunha M, Costa F, Ribeiro GS, Carvalho MS, Reis RB, Nery N, Pischel L, Gouveia EL, Santos AC, Queiroz A, Wunder EA, Reis MG, Diggle PJ, Ko AI. Rainfall and other meteorological factors as drivers of urban transmission of leptospirosis. PLOS Neglected Tropical Diseases 2022, 16: e0007507. PMID: 35404948, PMCID: PMC9022820, DOI: 10.1371/journal.pntd.0007507.Peer-Reviewed Original Research
2021
Bloodstream Infections in Children With Sickle Cell Disease: 2010-2019.
Yee ME, Lai KW, Bakshi N, Grossman JK, Jaggi P, Mallis A, Wang YF, Jerris RC, Lane PA, Yildirim I. Bloodstream Infections in Children With Sickle Cell Disease: 2010-2019. Pediatrics 2021, 149 PMID: 34913059, PMCID: PMC8959248, DOI: 10.1542/peds.2021-051892.Peer-Reviewed Original ResearchConceptsSickle cell diseaseBloodstream infectionsBlood culturesSickle cell anemia genotypesRetrospective cohort studyInvasive bacterial infectionsMultivariate logistic regressionConfidence intervalsAverage incidence rateSpectrum of pathogensAntibiotic prophylaxisEligible patientsFunctional aspleniaBSI episodesCohort studyChronic transfusionMedian ageAnnual incidenceOverall incidenceRisk factorsIncidence rateCell diseaseEmpirical treatmentBordetella holmesiiCommon pathogensChallenges of Diagnosing Viral Myocarditis in Adolescents in the Era of COVID‐19 and MIS‐C
Shah HP, Frye R, Chang S, Faherty E, Steele J, Karnik R. Challenges of Diagnosing Viral Myocarditis in Adolescents in the Era of COVID‐19 and MIS‐C. Case Reports In Pediatrics 2021, 2021: 4797498. PMID: 34616578, PMCID: PMC8490073, DOI: 10.1155/2021/4797498.Peer-Reviewed Case Reports and Technical NotesPediatric myocarditisElevated inflammatory markersMultisystem inflammatory syndromeShortness of breathDiagnosis of myocarditisSudden cardiac deathCOVID-19Electrocardiogram findingsInflammatory markersInflammatory syndromeChest tightnessCardiac deathMale presentingAnnual incidenceClinical presentationD-dimerViral myocarditisMyocardial injuryClinical conundrumSubclinical presentationMyocarditisRare diseaseClinical experienceTrue prevalenceCurrent Covid-19 pandemic eraSuicide Attempts in US Veterans with Chronic Headache Disorders: A 10-Year Retrospective Cohort Study
Androulakis XM, Guo S, Zhang J, Sico J, Warren P, Giakas A, Li X, Peterlin BL, Mathew R, Reyes D. Suicide Attempts in US Veterans with Chronic Headache Disorders: A 10-Year Retrospective Cohort Study. Journal Of Pain Research 2021, 14: 2629-2639. PMID: 34466030, PMCID: PMC8403028, DOI: 10.2147/jpr.s322432.Peer-Reviewed Original ResearchTraumatic brain injuryRisk of SAChronic pain conditionsChronic headacheChronic painSuicide attemptsPain conditionsAnnual incidenceHealth administrative dataHighest annual incidenceMultivariable Poisson regressionLarge-scale retrospective analysisChronic headPsychiatric comorbidityRetrospective studyBrain injuryRelative riskRetrospective analysisHeadachePainPoisson regressionVeteransAdministrative dataRiskDemographic factorsProvincial trends in Legionnaires’ disease are not explained by population structure in Denmark, 2015 to 2018
Cassell K, Thomas-Lopez D, Kjelsø C, Uldum S. Provincial trends in Legionnaires’ disease are not explained by population structure in Denmark, 2015 to 2018. Eurosurveillance 2021, 26: 2000036. PMID: 34169817, PMCID: PMC8229376, DOI: 10.2807/1560-7917.es.2021.26.25.2000036.Peer-Reviewed Original ResearchConceptsRisk of LDAge groupsSex distributionHigh incidenceIncidence of diseaseHighest annual incidenceRoutine surveillance dataUnexplained high incidencePoisson regression modelsAnnual incidenceIncidenceLD casesSurveillance dataDiseaseDisease incidenceDanish provinceLD incidenceHomogenous populationRegression modelsAgeProvincial trendsRiskYearly trendsPopulationGroup
2020
National Trends in Emergency Department Care Processes for Acute Myocardial Infarction in the United States, 2005 to 2015
Pendyal A, Rothenberg C, Scofi JE, Krumholz HM, Safdar B, Dreyer RP, Venkatesh AK. National Trends in Emergency Department Care Processes for Acute Myocardial Infarction in the United States, 2005 to 2015. Journal Of The American Heart Association 2020, 9: e017208. PMID: 33047624, PMCID: PMC7763391, DOI: 10.1161/jaha.120.017208.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionAcute myocardial infarctionMedian ED lengthUS emergency departmentsEmergency departmentED visitsMyocardial infarctionED administrationED lengthAMI careNational Hospital Ambulatory Medical Care SurveyCare processesAmbulatory Medical Care SurveyEvidence-based medicationsNonaspirin antiplatelet agentsEarly invasive strategyAnnual ED visitsRegionalization of careED care processesReal-world trendsAntiplatelet therapyAnnual incidenceAntiplatelet agentsYearly incidenceCare SurveyThe burden of respiratory syncytial virus infections among children with sickle cell disease
Rostad CA, Maillis AN, Lai K, Bakshi N, Jerris RC, Lane PA, Yee ME, Yildirim I. The burden of respiratory syncytial virus infections among children with sickle cell disease. Pediatric Blood & Cancer 2020, 68: e28759. PMID: 33034160, PMCID: PMC8246443, DOI: 10.1002/pbc.28759.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virusSickle cell diseaseRespiratory viral panelRSV-positive casesRSV infectionAnnual incidenceHospitalization ratesCell diseaseBurden of RSVPediatric lower respiratory tract infectionsLaboratory-confirmed RSV infectionRespiratory syncytial virus infectionRSV-related hospitalization rateLower respiratory tract infectionsRSV positive testRSV-negative childrenRSV-negative patientsAcute chest syndromeSyncytial virus infectionRespiratory tract infectionsAverage annual incidenceMultivariate logistic regressionConfidence intervalsCase-control studyOutcome of childrenPerioperative Transfusions and Venous Thromboembolism
Goel R, Josephson CD, Patel EU, Petersen MR, Makhani S, Frank SM, Ness PM, Bloch EM, Gehrie EA, Lokhandwala PM, Nellis MM, Karam O, Shaz BH, Patel RM, Tobian AAR. Perioperative Transfusions and Venous Thromboembolism. Pediatrics 2020, 145: e20192351. PMID: 32198293, PMCID: PMC7111487, DOI: 10.1542/peds.2019-2351.Peer-Reviewed Original ResearchConceptsPerioperative RBC transfusionPostoperative venous thromboembolismNational Surgical Quality Improvement ProjectVenous thromboembolismRBC transfusionRed blood cellsSurgeons National Surgical Quality Improvement ProjectDevelopment of VTESurgical Quality Improvement ProjectDay of surgeryMultivariable logistic regressionQuality improvement projectDose-dependent mannerPerioperative transfusionPostoperative transfusionTransfusion statusThird tertilePediatric patientsPostoperative developmentSecond tertileAnnual incidenceProspective studyTransfusion decisionsHospitalized childrenBody of evidence
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply