2024
Recommended guidelines for screening for underlying malignancy in extramammary Paget's disease based on anatomic subtype
Kibbi N, Owen J, Worley B, Alam M, Group E, Wang J, Harikumar V, Downing M, Aasi S, Aung P, Barker C, Bolotin D, Bordeaux J, Cartee T, Chandra S, Cho N, Choi J, Chung K, Cliby W, Dorigo O, Eisen D, Fujisawa Y, Golda N, Halfdanarson T, Iavazzo C, Jiang S, John E, Kanitakis J, Keimig E, Khan A, Linos E, Kim J, Kuzel T, Lawrence N, Leitao M, MacLean A, Maher I, Mittal B, Nehal K, Ozog D, Pettaway C, Rajan N, Ross J, Rossi A, Servaes S, Solomon M, Thomas V, Tolia M, Voelzke B, Waldman A, Wong M, Zhou Y, Brackett A, Poon E, Ahmed A. Recommended guidelines for screening for underlying malignancy in extramammary Paget's disease based on anatomic subtype. Journal Of The American Academy Of Dermatology 2024, 92: 261-268. PMID: 39401611, DOI: 10.1016/j.jaad.2024.07.1531.Peer-Reviewed Original ResearchExtramammary Paget's diseaseSecondary extramammary Paget's diseaseVulvar extramammary Paget diseasePerianal extramammary Paget's diseaseUrine cytologyAnatomic subtypesComputed tomographyPaget's diseaseProstate-specific antigen testingHigh-risk featuresOrgan-specific testsMultidisciplinary expert panelUnderlying malignancySystematic follow-upFollow-upAdenocarcinomaAntigen testAnatomical locationInclusion criteriaCytologyRetrospective dataScreening testSubtypesScreening algorithmRecommendation statementsNext-generation digital chest tomosynthesis
Gange C, Ku J, Gosangi B, Liu J, Maolinbay M. Next-generation digital chest tomosynthesis. Journal Of Clinical Imaging Science 2024, 14: 22. PMID: 38975057, PMCID: PMC11225395, DOI: 10.25259/jcis_4_2024.Peer-Reviewed Original ResearchRadiation doseLow dose chest CTLung phantomLung nodulesEffective radiation dosePlane resolutionLow radiation doseLow dose CTPhantomSimulated pulmonary nodulesChest CTChest radiologistsHealthy volunteersPulmonary nodulesDose CTAnatomical locationNodule detectionImaging characteristicsTomosynthesisNodulesLungDoseDetect lung nodulesDevicesPotential utility
2022
High-resolution cortical parcellation based on conserved brain landmarks for localization of multimodal data to the nearest centimeter
McGrath H, Zaveri H, Collins E, Jafar T, Chishti O, Obaid S, Ksendzovsky A, Wu K, Papademetris X, Spencer D. High-resolution cortical parcellation based on conserved brain landmarks for localization of multimodal data to the nearest centimeter. Scientific Reports 2022, 12: 18778. PMID: 36335146, PMCID: PMC9637135, DOI: 10.1038/s41598-022-21543-3.Peer-Reviewed Original ResearchConceptsEpilepsy surgery cohortStandardized brain regionsBrain structure-function relationshipsSurgery cohortClinical usefulnessBrain metricsAnatomical locationBrain regionsBrain localizationCortical parcellationOwn unique benefitsIntracranial electroencephalographyAnatomical designationBrain anatomyHuman brain anatomyHuman brainBrain atlasBrain landmarksBrain atlasesParcellationMagnetic resonanceNearest centimeterAnatomical featuresAnatomyCortical localizationDevelopment of an Accessible Gene Expression Bioinformatics Pipeline to Study Driver Mutations of Colorectal Cancer
van den Driest L, Johnson CH, Rattray NJW, Rattray Z. Development of an Accessible Gene Expression Bioinformatics Pipeline to Study Driver Mutations of Colorectal Cancer. Alternatives To Laboratory Animals 2022, 50: 282-292. PMID: 35765262, DOI: 10.1177/02611929221107546.Peer-Reviewed Original ResearchConceptsColorectal cancerBioinformatics toolsExpression patternsKirsten rat sarcoma viral oncogene homologueNext-generation sequencing technologiesDifferential expression patternsCancer-related mortalityGenetic alterationsAdenomatous polyposis coliEffector proteinsMutational driversPrognostic significancePrognostic valueSequencing technologiesBioinformatics pipelinePatient prognosisGenetic dataB-RafColorectal tumorsNovel biomarkersColon cancerTherapeutic outcomesFrequency of mutationsAnatomical locationOncogene homologue
2021
Cholangiocarcinoma
Lasagni A, Strazzabosco M, Guido M, Fabris L, Cadamuro M. Cholangiocarcinoma. 2021, 231-259. DOI: 10.1007/978-3-030-65908-0_14.Peer-Reviewed Original ResearchTypes of cholangiocarcinomaDifferent epithelial cancersLiver transplantationGastrointestinal malignanciesMost patientsSurgical resectionRich tumor microenvironmentCurative treatmentChronic inflammationNegative marginsAggressive tumorsBiliary treeRare cancersRisk factorsCholangiocarcinomaAdvanced stageEpithelial cancersAnatomical locationTumor microenvironmentPatientsDistinct cancersCancerDesmoplastic natureMultimodal approachLaboratory tests
2019
Molecular Pathway Analysis Indicates a Distinct Metabolic Phenotype in Women With Right-Sided Colon Cancer
Sun Y, Mironova V, Chen Y, Lundh EPF, Zhang Q, Cai Y, Vasiliou V, Zhang Y, Garcia-Milian R, Khan SA, Johnson CH. Molecular Pathway Analysis Indicates a Distinct Metabolic Phenotype in Women With Right-Sided Colon Cancer. Translational Oncology 2019, 13: 42-56. PMID: 31760268, PMCID: PMC6883319, DOI: 10.1016/j.tranon.2019.09.004.Peer-Reviewed Original ResearchRight-sided colon cancerLeft-sided colon cancerColon cancerAnatomical locationTumor tissueAnti-tumor immune responseGene Expression OmnibusImportant predictive markerPoor clinical outcomeTumor anatomical locationClinical outcomesPredictive markerPrimary tumorImmune phenotypeDistinct metabolic phenotypesImmune responseLower incidenceTreatment responseSex-specific differencesMolecular pathway analysisClinical importanceCancerProtein kinase alpha subunitBiotechnology Information Gene Expression OmnibusWomenLoop diuretic resistance complicating acute heart failure
Cox ZL, Testani JM. Loop diuretic resistance complicating acute heart failure. Heart Failure Reviews 2019, 25: 133-145. PMID: 31520280, DOI: 10.1007/s10741-019-09851-9.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsLoop diuretic resistanceDiuretic resistanceHeart failureAcute heart failure hospitalizationMechanism-based classification systemAcute heart failureHeart failure hospitalizationOngoing clinical trialsUniversal clinical applicationDiuretic strategyFailure hospitalizationDiuretic efficacyClinical trialsWorse outcomesTreatment pathwaysAnatomical locationClinical applicationCurrent literatureResistance mechanismsCurrent best practiceOutcomesClassification systemLiterature reviewHospitalizationPatientsIndiscriminate nature of lung resident CD8+ TRM cells reactivation and their varied reactivation profiles
LOW J, Amezcua C, Sefik E, Harman C, Jackson R, Jiang X, Kelly J, Cauley L, Flavell R, Kaech S. Indiscriminate nature of lung resident CD8+ TRM cells reactivation and their varied reactivation profiles. The Journal Of Immunology 2019, 202: 129.9-129.9. DOI: 10.4049/jimmunol.202.supp.129.9.Peer-Reviewed Original ResearchAntigen-presenting cellsTRM cellsCell reactivationTissue-resident memory cellsLong-term protective immunityLung-resident CD8Resident memory cellsKinetics of CD8Portal of infectionAbstract CD8Memory CD8Bystander activationInfluenza infectionProtective immunityResident CD8Heterologous immunityCD8T cellsPeripheral tissuesAnatomical locationReactivation profileInfectionReactivation kineticsImmediate protectionImmunity
2018
Treatment of persistent bronchopleural fistula with a manually modified endobronchial stent: a case-report and brief literature review
de Lima A, Holden V, Gesthalter Y, Kent M, Parikh M, Majid A, Chee A. Treatment of persistent bronchopleural fistula with a manually modified endobronchial stent: a case-report and brief literature review. Journal Of Thoracic Disease 2018, 10: 5960-5963. PMID: 30505507, PMCID: PMC6236168, DOI: 10.21037/jtd.2018.08.136.Peer-Reviewed Original ResearchBronchopleural fistulaEndobronchial stentsManagement of bronchopleural fistulaPersistent bronchopleural fistulaContralateral lungSurgical approachCase reportPatient comorbiditiesCornerstone of careTherapeutic strategiesAnatomical locationTherapeutic approachesStentFistulaSurgeryMorbidityPatientsComorbiditiesA common classification framework for neuroendocrine neoplasms: an International Agency for Research on Cancer (IARC) and World Health Organization (WHO) expert consensus proposal
Rindi G, Klimstra D, Abedi-Ardekani B, L. S, Bosman F, Brambilla E, Busam K, de Krijger R, Dietel M, El-Naggar A, Fernandez-Cuesta L, Klöppel G, McCluggage W, Moch H, Ohgaki H, Rakha E, Reed N, Rous B, Sasano H, Scarpa A, Scoazec J, Travis W, Tallini G, Trouillas J, van Krieken J, Cree I. A common classification framework for neuroendocrine neoplasms: an International Agency for Research on Cancer (IARC) and World Health Organization (WHO) expert consensus proposal. Modern Pathology 2018, 31: 1770-1786. PMID: 30140036, PMCID: PMC6265262, DOI: 10.1038/s41379-018-0110-y.Peer-Reviewed Original ResearchConceptsNeuroendocrine neoplasmsNeuroendocrine tumorsInternational Agency for Research on CancerExpression of neuroendocrine markersKi-67 labeling indexClassification of neuroendocrine neoplasmsWorld Health OrganizationPresence of necrosisOrgan systemsPrognostic factorsCarcinoid tumorsPrognostic differencesNeuroendocrine markersKi-67Mitotic countTumor biologyLabeling indexAnatomical sitesOrgan-specific differencesAnatomical locationConsensus conferenceNeoplasmsTumorClassification criteriaCancer
2015
Chapter 25 Mucosal Dendritic Cells Origins, Subsets, and Biology
Lambrecht B, Iwasaki A, Kelsall B. Chapter 25 Mucosal Dendritic Cells Origins, Subsets, and Biology. 2015, 489-541. DOI: 10.1016/b978-0-12-415847-4.00025-2.Peer-Reviewed Original ResearchDC populationsGenitourinary tractDendritic cell populationsDendritic cell originDC biologyCrohn's diseaseAllergic diseasesEnvironmental antigensDistinct anatomical locationsInflammatory conditionsUnique immunological functionsImmunological functionsSurface phenotypeImmune functionMucosal tissuesAnatomical locationCell originMaturation pathwayBarrier functionMajor portalCellular originDiseaseCell populationsFunctional equivalentAntigen
2014
Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence
Sumi NJ, Lima E, Pizzonia J, Orton SP, Craveiro V, Joo W, Holmberg JC, Gurrea M, Yang-Hartwich Y, Alvero A, Mor G. Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence. Journal Of Visualized Experiments 2014, 51815. PMID: 25407815, PMCID: PMC4353409, DOI: 10.3791/51815.Peer-Reviewed Original ResearchConceptsRecurrent ovarian cancerOvarian cancerVisible light rangeAnatomical locationOptical imaging platformAvailable chemotherapy agentsLethal gynecologic malignancyOvarian cancer recurrenceEpithelial ovarian cancerNovel therapy optionsAppropriate animal modelsMultiple angular positionsLight rangeIdentification of tumorsGynecologic malignanciesRecurrent diseaseSurgical debulkingChemoresistant diseaseCombination chemotherapyClinical profileNon-invasive imagingTherapy optionsCancer recurrenceX-rayChemotherapy agents
2010
Brown adipose tissue 18F-FDG uptake in pediatric PET/CT imaging
Hong T, Shammas A, Charron M, Zukotynski K, Drubach L, Lim R. Brown adipose tissue 18F-FDG uptake in pediatric PET/CT imaging. Pediatric Radiology 2010, 41: 759-768. PMID: 21161205, DOI: 10.1007/s00247-010-1925-y.Peer-Reviewed Original Research
2009
Phenotypic and Genotypic Characteristics of Inflammatory Bowel Disease in French Canadians: Comparison With a Large North American Repository
Elkadri A, Bitton A, Cohen A, Griffiths A, Deslandres C, Proctor D, McGovern D, Langelier D, Bernard E, Torres E, Wild G, Nguyen G, Jobin G, Aumais G, Steinhart H, Rioux J, Cho J, Bhat M, Silverberg M, Regueiro M, Goyette P, Pare P, Lahaie R, Duerr R, Brant S, Dassopoulos T. Phenotypic and Genotypic Characteristics of Inflammatory Bowel Disease in French Canadians: Comparison With a Large North American Repository. The American Journal Of Gastroenterology 2009, 104: 2233. PMID: 19513023, PMCID: PMC2742627, DOI: 10.1038/ajg.2009.267.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseCrohn's diseaseBowel diseaseUlcerative colitisSingle nucleotide polymorphismsManagement of IBDCaucasian IBD populationsSmall bowel diseaseFrench-Canadian patientsExtraintestinal manifestationsCurrent smokersFormer smokersIBD phenotypeIBD populationCD patientsSmoking statusIncreased prevalenceKidney diseaseSurgical historyCaucasian patientsDisease behaviorFamily historyPatientsAnatomical locationDisease
2007
Innate control of adaptive immunity: Dendritic cells and beyond
Lee HK, Iwasaki A. Innate control of adaptive immunity: Dendritic cells and beyond. Seminars In Immunology 2007, 19: 48-55. PMID: 17276695, DOI: 10.1016/j.smim.2006.12.001.Peer-Reviewed Original ResearchConceptsDendritic cellsAdaptive immune responsesImmune responseInnate immune recognitionKey cell typesCell typesEffector cellsNaïve lymphocytesAdaptive immunityInnate controlImmune recognitionAnatomical locationImmediate defensePathogen triggersCellsRecent understandingLymphocytesInfectionImmunityResponse
2005
Chapter G2 Animal Models of Tourette Syndrome
Burke K, Lombroso P. Chapter G2 Animal Models of Tourette Syndrome. 2005, 441-448. DOI: 10.1016/b978-012088382-0/50040-2.Peer-Reviewed Original ResearchAnimal modelsTourette syndromePartial animal modelsTic expressionPsychiatric disordersEntire syndromeSomatic diseasesPathological mechanismsPsychiatric syndromesSyndromeAnatomical locationNeuropsychiatric disordersAnimal preparationsDisease mechanismsDisordersMotor movementsSymptomsDiseaseSpecific human diseasesHuman diseasesTreatmentMedical researchEtiology
2004
Toll-like receptor control of the adaptive immune responses
Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nature Immunology 2004, 5: 987-995. PMID: 15454922, DOI: 10.1038/ni1112.Peer-Reviewed Original ResearchConceptsToll-like receptorsAdaptive immune responsesImmune responseMechanisms of TLRToll-like receptor controlHost defense responsesDendritic cell functionDendritic cell populationsMicrobial infectionsInnate immune systemDistinct anatomical locationsInflammatory reactionAdaptive immunityImmune systemAnatomical locationReceptor controlCell functionCell populationsMultiple mechanismsInfectionRecent studiesResponseInitiationSystemic defenseImportant clues
2000
CORRECTION OF PENOSCROTAL TRANSPOSITION: A NOVEL APPROACH
KOLLIGIAN M, FRANCO I, REDA E. CORRECTION OF PENOSCROTAL TRANSPOSITION: A NOVEL APPROACH. Journal Of Urology 2000, 164: 994-997. DOI: 10.1016/s0022-5347(05)67235-7.Peer-Reviewed Original Research
1995
Sensory phenomena in Tourette's syndrome.
Scahill LD, Leckman JF, Marek KL. Sensory phenomena in Tourette's syndrome. Advances In Neurology 1995, 65: 273-80. PMID: 7872145.Peer-Reviewed Original Research
1993
Single Photon Emission Computed Tomography in Obsessive-Compulsive Disorder
Harris G, Pearlson G, Hoehn-Saric R. Single Photon Emission Computed Tomography in Obsessive-Compulsive Disorder. JAMA Psychiatry 1993, 50: 498-499. PMID: 8498888, DOI: 10.1001/archpsyc.1993.01820180100015.Peer-Reviewed Original ResearchConceptsOrbital frontal regionsObsessive-compulsive disorderSingle photon emissionBlood flowRegional cerebral blood flowCortical blood flowGroup of patientsCerebral blood flowMedial frontal regionsSPECT studiesAnatomical locationPatientsCompulsive disorderPhoton emissionEt al1DisordersTomographyGroup
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