2024
Hypoxia-Directed Treatment of Human Papillomavirus–Related Oropharyngeal Carcinoma
Lee N, Sherman E, Schöder H, Wray R, Boyle J, Singh B, Grkovski M, Paudyal R, Cunningham L, Zhang Z, Hatzoglou V, Katabi N, Diplas B, Han J, Imber B, Pham K, Yu Y, Zakeri K, McBride S, Kang J, Tsai C, Chen L, Gelblum D, Shah J, Ganly I, Cohen M, Cracchiolo J, Morris L, Dunn L, Michel L, Fetten J, Kripani A, Pfister D, Ho A, Shukla-Dave A, Humm J, Powell S, Li B, Reis-Filho J, Diaz L, Wong R, Riaz N. Hypoxia-Directed Treatment of Human Papillomavirus–Related Oropharyngeal Carcinoma. Journal Of Clinical Oncology 2024, 42: 940-950. PMID: 38241600, PMCID: PMC10927322, DOI: 10.1200/jco.23.01308.Peer-Reviewed Original ResearchConceptsProgression-free survivalCurative-intent chemoradiotherapyLocoregional controlOropharyngeal carcinomaOverall survivalGrade 3Adverse eventsTumor hypoxiaHuman papillomavirus (HPV)-related oropharyngeal carcinomasHPV-related oropharyngeal carcinomaMedian follow-up timeHypoxic tumorsSurgical removal of diseaseAcute grade 3Late grade 3HPV-related carcinomasPhase II studyFollow-up timeMeasure tumor hypoxiaRemoval of diseaseDefinitive chemoradiotherapyStandard chemoradiotherapyGross diseaseLate dysphagiaOS rates
2023
Examining Preoperative MRI for Medial Meniscal Ramp Lesions in Patients Surgically Treated for Acute Grade 3 Combined Posterolateral Corner Knee Injury
Moran J, Jimenez A, Katz L, Wang A, McLaughlin W, Gillinov S, Patel R, Kunze K, Hewett T, Alaia M, LaPrade R, Medvecky M. Examining Preoperative MRI for Medial Meniscal Ramp Lesions in Patients Surgically Treated for Acute Grade 3 Combined Posterolateral Corner Knee Injury. Orthopaedic Journal Of Sports Medicine 2023, 11: 23259671221144767. PMID: 36756171, PMCID: PMC9900669, DOI: 10.1177/23259671221144767.Peer-Reviewed Original ResearchPreoperative magnetic resonance imagingMedial meniscal ramp lesionsAcute grade 3Meniscal ramp lesionsMultiligament knee injuriesMagnetic resonance imagingPosterolateral corner knee injuriesRamp lesionsPLC injuriesIntraclass correlation coefficientGrade 3Knee injuriesBone bruisingBone bruiseAnterior cruciate ligament injuryLevel 1 trauma centerCruciate ligament injuryDays of injuryCross-sectional studyLevel of evidenceMeniscocapsular tearsConsecutive patientsLigament injuryTrauma centerMultiligament reconstruction
2022
Repair of Acute Grade 3 Combined Posterolateral Corner Avulsion Injuries Using an Enhanced Fixation Technique
Moran J, Kahan J, Schneble C, McLaughlin W, Green J, Gillinov S, Cheng R, Patel R, Jimenez A, LaPrade R, Schenck R, Medvecky M. Repair of Acute Grade 3 Combined Posterolateral Corner Avulsion Injuries Using an Enhanced Fixation Technique. Orthopaedic Journal Of Sports Medicine 2022, 10: 23259671221131817. PMID: 36389620, PMCID: PMC9663643, DOI: 10.1177/23259671221131817.Peer-Reviewed Original ResearchInternational Knee Documentation CommitteePatient-reported outcome measuresMultiligament knee injuriesPeroneal nerve injuryAvulsion injuriesNerve injuryKrackow sutureLysholm scoreAcute repairKnee injuriesOutcome scoresMean International Knee Documentation CommitteePosterolateral cornerSubjective International Knee Documentation CommitteeSubjective outcome scoresAcute grade 3Level of evidenceFailure rateLower outcome scoresCruciate injuryTegner scoreCase seriesSurgical repairGraft augmentationSalvage procedureOutcomes and Toxicities of Nonmedullary Thyroid Tumors Treated with Proton Beam Radiation Therapy
Youssef I, Yoon J, Mohamed N, Zakeri K, Press R, Yu Y, Kang J, Wong R, Tuttle R, Shaha A, Sherman E, Lee N. Outcomes and Toxicities of Nonmedullary Thyroid Tumors Treated with Proton Beam Radiation Therapy. International Journal Of Particle Therapy 2022, 9: 20-30. PMID: 36060412, PMCID: PMC9415751, DOI: 10.14338/ijpt-22-00005.1.Peer-Reviewed Original ResearchPercent of patientsLocal-regional recurrenceThyroid cancerRadiation therapyGross diseaseOverall survivalPercutaneous endoscopic gastrostomy tubeProton therapyProton beam radiation therapyAcute grade 3Central neck compartmentFavorable therapeutic ratioIntensity-modulated radiation therapyBeam radiation therapyProton beam therapyConcurrent chemotherapyPalliative radiationUnresectable diseaseAdjuvant radiationDefinitive radiationT4 diseaseMetastatic diseaseNeck compartmentRegional recurrenceUpper mediastinum
2021
Dosimetric Comparison of Volumetric Modulated Arc Therapy with Tomotherapy Based Total Body Irradiation for Patients Undergoing Conditioning Prior to Hematopoietic Stem Cell Transplantation for Acute Lymphocytic Leukemia
Liveringhouse C, Robinson T, Garcia G, Peters J, Kim S, Latifi K. Dosimetric Comparison of Volumetric Modulated Arc Therapy with Tomotherapy Based Total Body Irradiation for Patients Undergoing Conditioning Prior to Hematopoietic Stem Cell Transplantation for Acute Lymphocytic Leukemia. International Journal Of Radiation Oncology • Biology • Physics 2021, 111: e303. DOI: 10.1016/j.ijrobp.2021.07.950.Peer-Reviewed Original ResearchHematopoietic stem cell transplantationTotal body irradiationAcute lymphocytic leukemiaStem cell transplantationPulmonary toxicityVMAT patientsBody irradiationSixteen patientsCell transplantationLung doseLymphocytic leukemiaHigh-dose total body irradiationAcute grade 3 diarrheaDose total body irradiationThermoplastic immobilizationVMAT plansGrade 3 diarrheaGrade 4 mucositisMean heart doseMean kidney doseResults Sixteen patientsAcute grade 3Common adverse eventsMean lung doseLate pulmonary toxicity
2011
Single-Fraction Stereotactic Body Radiation Therapy and Sequential Gemcitabine for the Treatment of Locally Advanced Pancreatic Cancer
Schellenberg D, Kim J, Christman-Skieller C, Chun CL, Columbo LA, Ford JM, Fisher GA, Kunz PL, Van Dam J, Quon A, Desser TS, Norton J, Hsu A, Maxim PG, Xing L, Goodman KA, Chang DT, Koong AC. Single-Fraction Stereotactic Body Radiation Therapy and Sequential Gemcitabine for the Treatment of Locally Advanced Pancreatic Cancer. International Journal Of Radiation Oncology • Biology • Physics 2011, 81: 181-188. PMID: 21549517, DOI: 10.1016/j.ijrobp.2010.05.006.Peer-Reviewed Original ResearchConceptsSingle-fraction stereotactic body radiotherapyAdvanced pancreatic cancerSequential gemcitabinePancreatic cancerGrade 3Local controlIntensity-modulated radiotherapy techniqueStereotactic body radiation therapyGreater nonhematologic toxicityLate grade 3Nonmetastatic pancreatic adenocarcinomaAcute grade 3Cycles of chemotherapyFraction Stereotactic Body Radiation TherapyExcellent local controlPhase II trialStereotactic body radiotherapyBody radiation therapyInternal target volumeInstitutional review boardNonhematologic toxicityAlive patientsII trialLocal progressionDuodenal perforation
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