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STEP LC - Overview of EIS - Module C - Session 5

April 01, 2025
ID
12985

Transcript

  • 00:02So for today, we're gonna
  • 00:04be continuing
  • 00:05with module c that we
  • 00:07started on last week,
  • 00:09continuing treatment in coordinated specialty
  • 00:11care.
  • 00:12Go to next.
  • 00:20So as we started last
  • 00:21week, these two sessions are
  • 00:23really focused on covering
  • 00:25step care in general, really
  • 00:27the bulk of it. So
  • 00:28talking about the structure, processes,
  • 00:30as well as outcomes,
  • 00:32that we focus on.
  • 00:34So last week, we started
  • 00:36to overview those six core
  • 00:38elements of care, which I'll
  • 00:39remind us of,
  • 00:41as well as introducing
  • 00:43discussions about different processes
  • 00:45that we engage in in
  • 00:47our,
  • 00:48step care model,
  • 00:50as well as, you know,
  • 00:51elements of kind of culture
  • 00:53and,
  • 00:54team cohesion and things like
  • 00:56that.
  • 00:57So we'll continue with those
  • 00:59discussions today. Next.
  • 01:03And everyone's favorite
  • 01:05favorite image, but just to
  • 01:06really hammer home that we'll
  • 01:07be focusing on module c
  • 01:09of the care pathway today.
  • 01:17And we'll,
  • 01:18outline these elements on the
  • 01:20next slide.
  • 01:23So as a reminder of
  • 01:24what we started talking about
  • 01:26last week, steps care model
  • 01:28is,
  • 01:30offers a variety and really
  • 01:31a menu of psychosocial services
  • 01:34for all of our,
  • 01:36participants. So, really,
  • 01:37this is based on
  • 01:40folks' phase of illness,
  • 01:42their needs, their preferences,
  • 01:45and various other elements.
  • 01:47So these offerings are available
  • 01:49to everyone in the clinic.
  • 01:50Some a bit more standard
  • 01:52than others.
  • 01:53But last week, we overviewed
  • 01:56what psychotherapy
  • 01:57looks like,
  • 02:00support for employment and education,
  • 02:02family support and education, as
  • 02:04well as coordination with community
  • 02:06supports, as well as within
  • 02:07team coordination.
  • 02:09So today,
  • 02:10we're gonna focus,
  • 02:11more so on
  • 02:13pharmacotherapy
  • 02:14and health promotion,
  • 02:15as well as,
  • 02:17discussing a bit of what
  • 02:18our kind of longitudinal
  • 02:19evaluation
  • 02:20process looks like.
  • 02:22So I'm gonna hand it
  • 02:23over,
  • 02:24to doctor Sreehari
  • 02:25to, start us off with
  • 02:27pharmacotherapy.
  • 02:30Thanks, Laura. And I,
  • 02:32know that Laura had covered
  • 02:34some of the other elements
  • 02:35of coordinated specialty care last
  • 02:37week. So
  • 02:39this is really the the
  • 02:40second session on it, and
  • 02:43I have just a few
  • 02:44slides,
  • 02:46with the hope that we'll
  • 02:47have time,
  • 02:48after the rest of the
  • 02:49session to
  • 02:51take questions or have discussions
  • 02:53about the entire module
  • 02:55c. So all the elements,
  • 02:56not just what we're talking
  • 02:58about today.
  • 02:59So for for pharmacologic treatment,
  • 03:03it's useful to think about
  • 03:04what their current targets are
  • 03:06given our current evidence base.
  • 03:07And
  • 03:08the the major target really
  • 03:10are the so called positive
  • 03:11symptoms, sometimes also called psychosis,
  • 03:14somewhat confusingly, but people are
  • 03:15often referring to,
  • 03:17delusions, hallucinations, and disorganization
  • 03:21that are really the most
  • 03:23rapidly
  • 03:24and,
  • 03:26routinely responsive to current antipsychotic
  • 03:29treatment.
  • 03:30The negative symptoms, unfortunately,
  • 03:32we don't really have good
  • 03:34evidence for any pharmacotherapies
  • 03:36that reliably target these. Although
  • 03:38in some trials and in
  • 03:40some patients, there can be
  • 03:41improvements in these symptoms,
  • 03:43and we can talk about
  • 03:44this more.
  • 03:46There are cognitive deficits that
  • 03:48we've spoken about that are,
  • 03:50a part of the illness
  • 03:52from many individuals with chronic
  • 03:54psychotic disorders
  • 03:55for which so far pharmacotherapies
  • 03:58are not a reliable tool.
  • 04:00There are several in development,
  • 04:02but since we're speaking here
  • 04:04about what's available for current
  • 04:06application in coordinated specialty care,
  • 04:09I've grayed that out.
  • 04:11And then finally, broadly, affective
  • 04:13dysregulation. So depressive and manic
  • 04:15symptoms can be part of
  • 04:17the syndrome of schizophrenia spectrum
  • 04:19disorders.
  • 04:21And here,
  • 04:22antipsychotic
  • 04:23medications
  • 04:24can actually help,
  • 04:25confusingly,
  • 04:27but we can also
  • 04:29use,
  • 04:29adjunctive treatments
  • 04:31from these other disorders. So
  • 04:33antidepressants,
  • 04:34anti manic agents can also
  • 04:36be helpful in managing,
  • 04:38symptoms and distress in chronic
  • 04:39psychotic illnesses.
  • 04:42Another sort of principle around
  • 04:45managing
  • 04:46with pharmacotherapy
  • 04:48is,
  • 04:49something I know Laura had
  • 04:50all already talked about. Individuals
  • 04:52early in the course of
  • 04:53these illnesses will often cycle
  • 04:55in and out of different
  • 04:56phases.
  • 04:57And this also means that
  • 04:59the goals for pharmacotherapy
  • 05:01will shift
  • 05:02based on the phase that
  • 05:03the person is in. The
  • 05:04most obvious example, of course,
  • 05:06is that when people are
  • 05:07brought into the emergency room
  • 05:08in the midst of an
  • 05:09acute
  • 05:10decompensation,
  • 05:11The the goal is often
  • 05:13initially to reduce aggression, hostility,
  • 05:16and, of course, to reduce
  • 05:17symptoms. But sometimes,
  • 05:20combinations of treatments might be
  • 05:21used at high doses
  • 05:24to really target
  • 05:25aggression
  • 05:27that might not be used
  • 05:29obviously in in the next
  • 05:30phase when individuals are,
  • 05:33are aiming towards
  • 05:35stability and preventing relapse.
  • 05:38And likewise, in the recovery
  • 05:40phase where often lower doses
  • 05:41can be used and sometimes
  • 05:43even, antipsychotics
  • 05:45can be tapered off in
  • 05:46a in selected patients.
  • 05:49So the strategy will vary
  • 05:51based on the phase,
  • 05:52of treatment,
  • 05:54that the patient is in.
  • 05:57And then this is a
  • 05:59a high level,
  • 06:01set of sessions. So I'm
  • 06:03listing out principles,
  • 06:05not to be intentionally vague,
  • 06:07but to point out that
  • 06:08for many of you who
  • 06:09are either
  • 06:11leading or overseeing or managing
  • 06:13care or providing care, I'm
  • 06:15hoping this will all look
  • 06:16fairly familiar,
  • 06:18and we adhere to these
  • 06:19principles at at Step as
  • 06:21well.
  • 06:23I should probably mention just
  • 06:24a couple, which is
  • 06:27that we we like to
  • 06:28favor
  • 06:29using interventions that have been
  • 06:31actually studied in rigorous trials
  • 06:34first.
  • 06:35And when we've exhausted those,
  • 06:37we move to more theoretically
  • 06:39based interventions
  • 06:41or relying on clinical experience.
  • 06:42And so what I mean
  • 06:43by that is often first
  • 06:45line agents for
  • 06:47psychotic symptoms or depressive symptoms
  • 06:49or manic symptoms.
  • 06:52We have several of them,
  • 06:54and so we tend to
  • 06:55reach for ones that have
  • 06:56survived clinical studies,
  • 06:58before we reach for more
  • 07:00unconventional treatments that sometimes individual
  • 07:03patients may already be on
  • 07:05when they come to us.
  • 07:06And we reserve those only
  • 07:08for those who do not
  • 07:09respond to first line treatments.
  • 07:12And we can talk about
  • 07:12that more.
  • 07:14There are several agents, for
  • 07:15example, that have been studied
  • 07:17to treat cognition
  • 07:19that unfortunately
  • 07:20have not survived
  • 07:21clinical trials,
  • 07:22and yet individuals will often
  • 07:24be using them or be
  • 07:26asking for them.
  • 07:28And
  • 07:29it is certainly permitted for
  • 07:31prescribers to use medications off
  • 07:33label, but we prefer to
  • 07:34start with ones that have
  • 07:36a good solid evidence base,
  • 07:38in human studies.
  • 07:41I won't read the rest
  • 07:42out, but I put this
  • 07:43up in part because I
  • 07:44knew we were gonna leave
  • 07:45this on the website as
  • 07:46a recording so individuals could
  • 07:48pause and look at the
  • 07:49list.
  • 07:50And I'm happy to take
  • 07:51questions about it. Another one
  • 07:52I should point out though
  • 07:53is, treating to remission, which
  • 07:56is that in early COVID
  • 07:57patients, this is a very
  • 07:59reasonable goal
  • 08:01to drive,
  • 08:02positive psychotic symptoms to remission.
  • 08:04And this sometimes takes
  • 08:06persistence around getting to a
  • 08:08good enough dose,
  • 08:10which is optimal to reduce
  • 08:12symptoms while also managing side
  • 08:14effects.
  • 08:15But in fact, somewhere,
  • 08:17north of seventy five percent
  • 08:19of patients
  • 08:20with our current medications, mostly
  • 08:22first or second line, can
  • 08:24reach remission within the first
  • 08:25six months to a year
  • 08:27of,
  • 08:27psychosis. So,
  • 08:29this is something that we
  • 08:30we try very hard to
  • 08:32to achieve.
  • 08:34Doctor Sheheri, there's a question,
  • 08:37just saying looking for clarification.
  • 08:39When you mentioned combination treatments,
  • 08:41are we referring to multiple
  • 08:42antipsychotics
  • 08:43or antipsychotics
  • 08:45mixed with other medications such
  • 08:47as antidepressants or mood stabilizers?
  • 08:50Yeah. Great.
  • 08:51All of the above. And
  • 08:53part of the rationale is
  • 08:55we know that when you
  • 08:55add a second medication,
  • 08:57the risks of nonadherence
  • 08:59start going up exponentially. And
  • 09:01when you add a third
  • 09:02and a fourth, this is
  • 09:03not just in patients with
  • 09:04psychosis, but all of us.
  • 09:06Medication regimens that are that
  • 09:09include multiple medicines multiple times
  • 09:11a day can be very
  • 09:12hard to
  • 09:13adhere to.
  • 09:15So one then ends up
  • 09:17with very unreliable doses of
  • 09:19multiple medicines over time, and
  • 09:20it becomes difficult to figure
  • 09:22out which medicine is causing
  • 09:23what side effect,
  • 09:25especially given that some of
  • 09:26our medications are the most
  • 09:28difficult to take early on
  • 09:30when the body is beginning
  • 09:31to adapt. And so stopping
  • 09:33and starting and forgetting just
  • 09:35adds to the side effect
  • 09:36burden, and then you have
  • 09:37a patient who's
  • 09:39demoralized and unhappy. And and
  • 09:41then looks like they failed
  • 09:43a trial of a medication
  • 09:44when they haven't even actually
  • 09:46had an adequate dose for
  • 09:48long enough. So
  • 09:49so so all of that.
  • 09:51It it I didn't say,
  • 09:53I I wouldn't say that
  • 09:54we completely avoid combination treatments,
  • 09:56but we try very hard
  • 09:57to limit them and use
  • 09:59one medicine
  • 10:00at a time if we
  • 10:01can get away with it.
  • 10:06Any other,
  • 10:07we can come back to
  • 10:07this, of course, so I'll
  • 10:08keep plugging on, but feel
  • 10:09free to to interrupt.
  • 10:11So, again, at a high
  • 10:12level, this is roughly,
  • 10:14what we try and follow.
  • 10:16There are published algorithms that
  • 10:18have been implemented in clinics
  • 10:21and that have shown,
  • 10:23greater rates of response and
  • 10:25remission,
  • 10:27and better progression
  • 10:29to to second line agents
  • 10:31and then clozapine.
  • 10:33So I think there are
  • 10:34ways to police,
  • 10:35prescription practice in a service
  • 10:38that will result in better
  • 10:40practice and outcomes for patients.
  • 10:43And at step, we the
  • 10:45way we do this is
  • 10:46not through,
  • 10:47some kind of formal algorithm,
  • 10:49but really
  • 10:50a a culture of practice
  • 10:51where we are constantly reviewing
  • 10:53our medication choices with each
  • 10:55other as a clinic and
  • 10:57amongst prescribers,
  • 10:59and, of course, trying to
  • 11:00follow the principles I I
  • 11:02put in earlier. But in
  • 11:03general, for early psychosis, the
  • 11:05good news is that
  • 11:07any of the, agents available,
  • 11:10both first and second generation,
  • 11:12are appear to be equally
  • 11:13effective at driving towards remission
  • 11:16as long as the individual
  • 11:17patient can tolerate that medication.
  • 11:19So sometimes the game is
  • 11:20to find a medication for
  • 11:22which the patient is best
  • 11:24able to tolerate the side
  • 11:25effects.
  • 11:26I put accept olanzapine
  • 11:28not because it's any less
  • 11:29effective, but because its
  • 11:31impact on weight gain is
  • 11:33so dramatically worse than the
  • 11:34other medications that,
  • 11:36it would be a shame
  • 11:37to try it first and
  • 11:38end up with someone who
  • 11:40is in remission but who's
  • 11:41gained thirty pounds in the
  • 11:42first three months. And then
  • 11:43you have to figure out
  • 11:45what to do next. Take
  • 11:46them off this medicine and
  • 11:47and transition them.
  • 11:51If they don't respond to
  • 11:52the first medication, it's entirely
  • 11:54reasonable to try another. The
  • 11:55people often favor trying something
  • 11:57from a different class,
  • 11:59but I found sometimes they're
  • 12:00just trying a different medication
  • 12:02that's better tolerated,
  • 12:04that for which the individual
  • 12:05patient feels subjectively better,
  • 12:08which can be idiosyncratic
  • 12:10amongst individual patients. Some like,
  • 12:12the sedating and slowing effects
  • 12:14of something like Seroquel, and
  • 12:16others prefer Abilify because it
  • 12:17makes them feel less sleepy.
  • 12:19So,
  • 12:21it's worth trying a second
  • 12:22agent and getting it, to
  • 12:24a to an optimal dose.
  • 12:26And then there are caveats,
  • 12:27of course. So,
  • 12:29we can talk about this
  • 12:30more, but clozapine, of course,
  • 12:32is severely underutilized.
  • 12:34Individual patients,
  • 12:37who would be responsive to
  • 12:38clozapine often go through unnecessary
  • 12:42trials,
  • 12:43beyond
  • 12:44a second trial, a third
  • 12:45trial, a fourth trial, and
  • 12:47then get put on multiple
  • 12:48antipsychotics
  • 12:49when
  • 12:50the evidence is very clear
  • 12:51that for individuals who've tried
  • 12:53who've gone through two trials
  • 12:54and not remitted,
  • 12:56clozapine is really the best
  • 12:57medication. So it should at
  • 12:59least be discussed and often
  • 13:00needs to be discussed many
  • 13:01times before
  • 13:03families and individual patients will
  • 13:05feel comfortable proceeding.
  • 13:07And, of course, injectable medications,
  • 13:10the long acting injectable medications
  • 13:12are a great tool, and
  • 13:14we,
  • 13:15will often move to this
  • 13:17even in the first trial
  • 13:18or sometimes the second trial.
  • 13:20If we find that a
  • 13:21person has responded to oral
  • 13:23medications,
  • 13:24it
  • 13:25the question should be why
  • 13:26not an LAI in those
  • 13:28situations. It's,
  • 13:30allows individuals to not have
  • 13:31to remember, of course, to
  • 13:32take it every day, but
  • 13:34it can also save individual
  • 13:36individuals from
  • 13:37exposure to others if they're
  • 13:38living in community settings and
  • 13:40colleges and dorms
  • 13:42where they don't have to
  • 13:43carry pill bottles around, can
  • 13:44come into a clinic once
  • 13:45a month and get an
  • 13:46injection.
  • 13:48And it also allows us
  • 13:49to use much effectively much
  • 13:51lower doses with much lower
  • 13:53side effects than oral medications.
  • 13:55So,
  • 13:56we have a very strong
  • 13:57preference
  • 13:58and try very hard to
  • 13:59educate,
  • 14:00patients and families to move
  • 14:02towards an LAI
  • 14:03once they've responded to an
  • 14:05an oral, medication.
  • 14:09And we can talk more
  • 14:11about this. There are some
  • 14:11individuals who don't respond to
  • 14:13clozapine.
  • 14:14And at that point, we
  • 14:15have moved beyond
  • 14:17the evidence from clinical studies,
  • 14:19and we end up having
  • 14:20to use combination treatments based
  • 14:22on
  • 14:23mechanisms of action, ideas that
  • 14:25might be helpful for an
  • 14:26individual patient.
  • 14:28And then if that fails
  • 14:30too, ECT can be quite
  • 14:32effective in those situations and
  • 14:33is worth considering.
  • 14:35And I would say if
  • 14:37that isn't available or if
  • 14:38an individual patient hasn't responded,
  • 14:41beyond stage five, it makes
  • 14:43sense to look, for clinical
  • 14:45trials of which,
  • 14:46if you're near an academic
  • 14:48center, could be enrolling subjects
  • 14:50who could then try experimental
  • 14:51treatments in a much safer
  • 14:53environment,
  • 14:54than in ordinary clinical practice.
  • 14:59And we've got one more
  • 15:01med related question that was
  • 15:02relevant.
  • 15:04So just wondering if we,
  • 15:06generally speaking,
  • 15:08doing more favors starting an
  • 15:09injection while a client is
  • 15:11inpatient or trying it through
  • 15:13the outpatient prescriber.
  • 15:18Yeah. That's a great question.
  • 15:20It's
  • 15:21it's great if individuals can
  • 15:24be loaded on an LAI
  • 15:26after having shown a response
  • 15:28on an inpatient unit.
  • 15:31It it certainly helps us
  • 15:33a lot when we begin
  • 15:34to engage someone that they
  • 15:35have already begun in LAI.
  • 15:38So
  • 15:39that would require though communication
  • 15:41and collaboration with an inpatient
  • 15:43unit,
  • 15:44and
  • 15:45sometimes reassuring them that you
  • 15:47are able to continue in
  • 15:49LAI.
  • 15:50But we've also started individuals
  • 15:52in the outpatient setting on
  • 15:54on LAI. So, I don't
  • 15:56know if that answers the
  • 15:56question, but but any any
  • 15:58pathway to an LAI is
  • 16:00good. There are some barriers
  • 16:02that we can talk about,
  • 16:03one of which unfortunately often
  • 16:04is insurance coverage.
  • 16:08But but, yeah, if if,
  • 16:09an individual gets admitted to
  • 16:11a hospital
  • 16:13and you as an outpatient
  • 16:14provider have a sense that
  • 16:15they have responded to a
  • 16:16medication,
  • 16:18it's a great time to
  • 16:19engage with the inpatient team
  • 16:21and
  • 16:22help collaborate with them and
  • 16:24the family to get them,
  • 16:26started on LAI,
  • 16:28you know, before they leave.
  • 16:32Any anything else, Laura? Any
  • 16:33other questions?
  • 16:35No. Thank you.
  • 16:40So I think this is
  • 16:42almost my last slide, and
  • 16:43I put this up again
  • 16:44intentionally. It's it's a very
  • 16:46long list. I won't go
  • 16:46through it. But the point
  • 16:48I'm I was trying to
  • 16:48make here is that, of
  • 16:49course,
  • 16:50pharmacotherapy,
  • 16:52for people with schizophrenia spectrum
  • 16:54disorders,
  • 16:57can accomplish a lot in
  • 16:58terms of positive symptom remission.
  • 17:01As I mentioned before,
  • 17:02it can't do much for
  • 17:04cognitive symptoms or negative symptoms.
  • 17:06And so
  • 17:07it's very important to integrate
  • 17:09these interventions with all the
  • 17:11other components of coordinated specialty
  • 17:13care.
  • 17:14But within,
  • 17:16just the pharmacotherapy
  • 17:17domain, there are opportunities
  • 17:19within a collaborative like this
  • 17:21where we need to bring
  • 17:22clinics together
  • 17:25to think about more systematic
  • 17:26ways to,
  • 17:28tackle problems that we all
  • 17:30know keep coming up. And
  • 17:32I've listed a few here.
  • 17:34There are ways to think
  • 17:35about,
  • 17:37care pathways. In other words,
  • 17:38sort of standardized
  • 17:40processes that can help all
  • 17:41of us
  • 17:43improve on problems like clozapine
  • 17:45underutilization.
  • 17:47So there are tools available
  • 17:48that can help clinicians educate
  • 17:51patients and families with standard
  • 17:52language, for example.
  • 17:55And then there are ways
  • 17:56to jointly screen for rare
  • 17:58side effects across,
  • 18:00state a statewide network like
  • 18:02this
  • 18:02where we can all be
  • 18:04helpful to each other in
  • 18:05how to actually utilize these
  • 18:06screening measures appropriately
  • 18:08and educate patients and families
  • 18:10about risks.
  • 18:12So,
  • 18:13adherence is another, obviously, a
  • 18:14very common challenge, and there
  • 18:16are many different ways that
  • 18:18can be helpful for different
  • 18:19patients using visiting nurses, doing
  • 18:21pill counts. But these are
  • 18:23the kinds of challenges that
  • 18:24I think sometimes
  • 18:25if you're in a larger
  • 18:26network,
  • 18:28it it's useful to do
  • 18:29together and share tools around
  • 18:31this that can help everyone
  • 18:33try out these different approaches
  • 18:35that they may not, as
  • 18:36a clinic, have tried before,
  • 18:38but they may be,
  • 18:39a, sort of an activation
  • 18:41barrier to getting it started.
  • 18:42If you don't have the
  • 18:43materials printed out,
  • 18:45it takes a lot of
  • 18:46work. But if one clinic
  • 18:47has it printed out, these
  • 18:48can be shared. So
  • 18:50part of my excitement is
  • 18:51is that I think
  • 18:52we all are probably,
  • 18:55using creative ways to tackle
  • 18:57some more more of these
  • 18:58problems in pharmacotherapy.
  • 19:00And by pooling our knowledge,
  • 19:02we could probably all do
  • 19:03better as a network,
  • 19:05in getting at these. And
  • 19:07none of this is,
  • 19:09is requires
  • 19:11any special,
  • 19:13equipment
  • 19:13or,
  • 19:15or tools, but it it
  • 19:17does require sharing sort of
  • 19:19standard
  • 19:20lessons and and maybe
  • 19:22informational materials and so on.
  • 19:24And I can say more
  • 19:25about this later because we
  • 19:27are
  • 19:28soon gonna be,
  • 19:29launching, I'm hoping in July,
  • 19:32a consultation service out of
  • 19:34step for
  • 19:35clinicians across the state to
  • 19:36call just to curbside around
  • 19:38some of these challenges with
  • 19:40not just pharmacotherapy, but we
  • 19:41expect many of them will
  • 19:42be around pharmacotherapeutic,
  • 19:45issues.
  • 19:47So, so we're back here
  • 19:50to where we started. And,
  • 19:52the other component,
  • 19:54we're gonna address is longitudinal
  • 19:56evaluation. So
  • 20:00we we regard sort of
  • 20:02keeping an open mind and
  • 20:03continuing to evaluate as a
  • 20:05core
  • 20:07value at step,
  • 20:09and it it varies, of
  • 20:10course, across the modules. So
  • 20:12in module a,
  • 20:14where we're often engaged with
  • 20:16families and referral sources
  • 20:19before they arrive in the
  • 20:20clinic,
  • 20:21we are gathering a lot
  • 20:22of information that's very helpful
  • 20:24in evaluating
  • 20:26the the patient, but also
  • 20:27understanding their delays, their pathways
  • 20:29to care, understanding
  • 20:31the network that they had
  • 20:33to travel through to get
  • 20:34into the clinic.
  • 20:35And also the interactions with
  • 20:37family members in the course
  • 20:38of engaging a person into
  • 20:39care can provide incredibly valuable
  • 20:42information about the concerns, the
  • 20:44capabilities,
  • 20:44the issues that family members
  • 20:46have, and the environment
  • 20:48from which the patient is
  • 20:49coming to the clinic.
  • 20:51So it our assessments really
  • 20:53and evaluations begin before the
  • 20:55person hits the front door.
  • 20:57When they are in the
  • 20:58clinic, it looks a little
  • 20:59bit more like a traditional
  • 21:01clinical evaluation that I'm sure
  • 21:02you're all engaged with.
  • 21:04And the idea here, of
  • 21:05course, is to
  • 21:07to conduct a careful differential
  • 21:09diagnosis to rule out,
  • 21:11secondary causes of psychosis that
  • 21:13we'll be covering in more
  • 21:15detail next week. I know
  • 21:17we flipped the modules because
  • 21:18of of my absence last
  • 21:20week, but we'll be talking
  • 21:21about module b in more
  • 21:23detail.
  • 21:24We also engage in a
  • 21:26more pluralistic case formulation.
  • 21:28So not just what illness
  • 21:30the patient might have and
  • 21:31the differential diagnosis of the
  • 21:33different possibilities,
  • 21:35but also who they are,
  • 21:36what sort of behavioral issues
  • 21:37they have or are having,
  • 21:39and their own life story
  • 21:41and how to, build a
  • 21:42narrative
  • 21:43that helps make the best
  • 21:44sense of how to, improve
  • 21:46their
  • 22:00improve their capability in the
  • 22:02world. So,
  • 22:04that point,
  • 22:05we have a formal presentation
  • 22:07in our clinic
  • 22:09of,
  • 22:09an overall assessment that includes
  • 22:12the workup and differential diagnosis
  • 22:14so far, a case formulation,
  • 22:16and a chance for other
  • 22:17members of the clinic who
  • 22:19are not the primary caregivers
  • 22:21to weigh in and critique
  • 22:23and raise questions about management,
  • 22:26in in in a sort
  • 22:27of a a case conference
  • 22:29mode, but really as a
  • 22:30way of allowing the primary
  • 22:32clinical team to get a
  • 22:33second opinion from within the
  • 22:34team
  • 22:36on on managing various issues
  • 22:37as they've come up.
  • 22:39So so that can that
  • 22:40happens at three months, and
  • 22:41then every six months, we
  • 22:43have a standard over, overall
  • 22:45review of of,
  • 22:46progress in the case.
  • 22:48And we
  • 22:49you know, with these illnesses,
  • 22:52the best diagnostic tool is
  • 22:54longitudinal
  • 22:55follow-up. So
  • 22:56there are individual
  • 22:59cases where it's very hard
  • 23:01to figure out the relative
  • 23:02contribution of substance use versus
  • 23:04personality dysfunction versus the primary
  • 23:07psychotic illness. And this is
  • 23:09only clear
  • 23:11as we get to know
  • 23:12people over time. And so
  • 23:13it's important to
  • 23:14revisit the formulation,
  • 23:16periodically within the team setting
  • 23:18to make sure that we're
  • 23:19providing
  • 23:20the best care. So
  • 23:21I I think that Laura
  • 23:23wanted me to just remind
  • 23:24us and all of you
  • 23:26about the importance of
  • 23:28continued evaluation in a clinic
  • 23:29like this even while it's
  • 23:30organized around
  • 23:32a group of, disorders that
  • 23:34fall within schizophrenia.
  • 23:36We recognize there's a lot
  • 23:37of heterogeneity
  • 23:38within that comorbidity
  • 23:39with other,
  • 23:41substance use disorders and behavioral,
  • 23:43disorders.
  • 23:44And so we we try
  • 23:45to keep that as part
  • 23:47of our ethos in the
  • 23:48clinic and keep reevaluating,
  • 23:51in a team whether we're
  • 23:53missing something or need to
  • 23:55address something we hadn't picked
  • 23:56up at the initial assessment.
  • 24:02And,
  • 24:04so,
  • 24:05the last slide here I
  • 24:07I think this is the
  • 24:07last slide. Yes. Good.
  • 24:09Is to return to this
  • 24:11issue of of culture and
  • 24:13how important
  • 24:15it is.
  • 24:17I know Laura talked a
  • 24:18little bit about Huddl, which
  • 24:19is one of my favorite,
  • 24:21meetings in the clinic.
  • 24:22It's a chance to do
  • 24:23many different things, but also
  • 24:25to
  • 24:26make sure that the values
  • 24:27that we espouse as a
  • 24:28service that is inclusive, open,
  • 24:31providing the most effective care,
  • 24:34is accessible
  • 24:35to families and patients where
  • 24:36we're constantly reevaluating
  • 24:39is actually happening in the
  • 24:40course of care,
  • 24:42even as we're discussing,
  • 24:44issues that arise that might
  • 24:46be acute and
  • 24:47require a change in the
  • 24:48plan,
  • 24:50and a chance to also
  • 24:51assess how the team is
  • 24:52doing and whether they feel
  • 24:54supported and whether they're managing
  • 24:55under,
  • 24:57the the stress of having
  • 24:59to provide
  • 25:00lots at different times to
  • 25:02different people who may be
  • 25:03cycling in and out of
  • 25:05stability and recovery and then
  • 25:06relapse again.
  • 25:08We try to use our
  • 25:10data that we collect as
  • 25:12part of these assessments,
  • 25:14to help clinicians
  • 25:15understand their impact on the
  • 25:17population's health. So
  • 25:19the goal here is to,
  • 25:22help everyone see
  • 25:24what the clinic is able
  • 25:25to accomplish
  • 25:26in terms of reducing relapse
  • 25:28and rehospitalization
  • 25:29and improving
  • 25:30vocational outcomes.
  • 25:31And I'll say a little
  • 25:33bit more about this at
  • 25:34the last session where we
  • 25:35will talk a little bit
  • 25:36more about how we use
  • 25:38the structured assessments we collect
  • 25:40to help the clinic navigate,
  • 25:43and get feedback on what
  • 25:45it should do in terms
  • 25:46of its care processes.
  • 25:48Such that if we discover,
  • 25:49for example, that our rates
  • 25:51of
  • 25:52smoking have been going up
  • 25:54quarter on quarter,
  • 25:55we can have a discussion
  • 25:56at the clinic level about
  • 25:57what we might do,
  • 25:59around smoking cessation efforts and
  • 26:02and educational efforts with our
  • 26:03patients. So it's a shared
  • 26:05project together
  • 26:07to use data to help
  • 26:08everyone improve population outcomes.
  • 26:13And
  • 26:13we we've tried
  • 26:15over the the years to,
  • 26:18connect our clinicians to activities
  • 26:20for their own professional development,
  • 26:22CME, but also
  • 26:23inviting discussions into the clinic
  • 26:25to talk about difficult cases,
  • 26:29presentations,
  • 26:30and opportunities to present at
  • 26:32local conferences where clinicians
  • 26:35have acquired specific expertise
  • 26:37that they can use to
  • 26:38teach others.
  • 26:40And I'm hoping actually that
  • 26:42one big growth opportunity for
  • 26:43our step clinicians over the
  • 26:44next few years will be
  • 26:46interacting with,
  • 26:48with all of you in
  • 26:49your clinics and sharing,
  • 26:51lessons they've learned as as
  • 26:53expert clinicians with others, their
  • 26:55peers,
  • 26:56which I think can be,
  • 26:58a huge value add to
  • 26:59the to the work that
  • 27:01we do together and can
  • 27:02prevent,
  • 27:03we hope, you know, the
  • 27:05kind
  • 27:07of, demoralization
  • 27:08that can sink in if
  • 27:09you feel like you're you're
  • 27:10not getting adequate feedback or
  • 27:12you're not getting better
  • 27:14at your job.
  • 27:16So I'll stop there because
  • 27:17I'm anxious to give us
  • 27:19as much time as possible
  • 27:20to to
  • 27:21to engage.