What is the purpose of this trial?
To establish behavioral and neuroimaging metrics of memory reconsolidation in humans, examine the modulation of memory reconsolidation by ketamine with this paradigm, relate subjective responses to ketamine to brain and behavioral metrics of reconsolidation, record the effects of ketamine and memory reconsoloidation on subjects sleep quality and to refine a learning and memory model of psychotic symptoms by relating ketamines experiential effects to its impact upon learning, memory formation and post-formation processing of memories.
Ages: 21 - 45 years
Yale University School of Medicine
Dates: 01/23/2014 - 12/31/2015
Last Updated: 12/10/2017
Study HIC#: 1311013013