Selected Publications

Zhou H, Cheng Z, Bass N, Krystal JH, Farrer LA, Kranzler HR, Gelernter J. Genome-wide association study identifies glutamate ionotropic receptor GRIA4 as a risk gene for comorbid nicotine dependence and major depression. Transl Psychiatry. 2018 Oct 4;8(1):208. doi: 10.1038/s41398-018-0258-8. PMID: 30287806.

Cheng Z, Zhou H, Sherva R, Farrer LA, Kranzler HR, Gelernter J. Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated with Opioid Dependence in European Americans. Biol Psychiatry. 2018 Nov 15;84(10):762-770. doi: 10.1016/j.biopsych.2017.12.016. Epub 2018 Jan 11. PMID: 29478698.

Montalvo-Ortiz JL, Zhou H, D'Andrea I, Maroteaux L, Lori A, Smith A, Ressler KJ, Nuñez YZ, Farrer LA, Zhao H, Kranzler HR, Gelernter J. Translational studies support a role for serotonin 2B receptor (HTR2B) gene in aggression-related cannabis response. Mol Psychiatry. 2018 Jun 6. doi: 10.1038/s41380-018-0077-6. [Epub ahead of print] PMID: 29875475.

Polimanti R, Kayser MH, Gelernter J. Local adaptation in European populations affected the genetics of psychiatric disorders and behavioral traits. Genome Med. 2018 Mar 26;10(1):24. doi: 10.1186/s13073-018-0532-7. PMID: 29580271.

Montalvo-Ortiz JL, Zhang H, Chen C, Liu C, Coccaro EF. Genome-Wide DNA Methylation Changes Associated with Intermittent Explosive Disorder: A Gene-Based Functional Enrichment Analysis. Int J Neuropsychopharmacol. 2018 Jan 1;21(1):12-20. doi: 10.1093/ijnp/pyx087. PMID: 29106553.

Zhou H, Polimanti R, Yang BZ, Wang Q, Han S, Sherva R, Nuñez YZ, Zhao H, Farrer LA, Kranzler HR, Gelernter J. Genetic Risk Variants Associated with Comorbid Alcohol Dependence and Major Depression. JAMA Psychiatry. 2017 Dec 1;74(12):1234-1241. doi: 10.1001/jamapsychiatry.2017.3275. PMID: 29071344.

Yang BZ, Arias AJ, Feinn R, Krystal JH, Gelernter J, Petrakis IL. GRIK1 and GABRA2 Variants Have Distinct Effects on the Dose-Related Subjective Response to Intravenous Alcohol in Healthy Social Drinkers. Alcohol Clin Exp Res. 2017 Dec;41(12):2025-2032. doi: 10.1111/acer.13516. Epub 2017 Nov 13. PMID: 29131352.

Yang BZ, Han S, Kranzler HR, Palmer AA, Gelernter J. Sex-specific linkage scans in opioid dependence Am J Med Genet B Neuropsychiatr Genet. 2017 Apr;174(3):261-268. doi: 10.1002/ajmg.b.32507. Epub 2016 Oct 20. PMID: 27762075.

Smith AH, Jensen KP, Li J, Nunez Y, Farrer LA, Hakonarson H, Cook-Sather SD, Kranzler HR, Gelernter J. Genome-wide association study of therapeutic opioid dosing identifies a novel locus upstream of OPRM1. Mol Psychiatry. 2017 Mar;22(3):346-352. doi: 10.1038/mp.2016.257. Epub 2017 Jan 24. PMID: 28115739.

Polimanti R, Gelernter J. Widespread signatures of positive selection in common risk alleles associated to autism spectrum disorder. PLoS Genet. 2017 Feb 10;13(2):e1006618. doi: 10.1371/journal.pgen.1006618. eCollection 2017 Feb. PMID: 28187187.

Sherva R, Wang Q, Kranzler H, Zhao H, Koesterer R, Herman A, Farrer LA, Gelernter J. Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks. JAMA Psychiatry. 2016 May 1;73(5):472-80. doi: 10.1001/jamapsychiatry.2016.0036. PMID: 27028160.

Main PubMed Publications

Kranzler HR, Zhou H, Kember RL, Smith RV, Justice AC, Damrauer S, Tsao PS, Klarin D, Baras A, Reid J, Overton J, Rader DJ, Cheng Z, Tate JP, Becker WC, Concato J, Xu K, Polimanti R, Zhao H, Gelernter J: Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. Nat Commun. 2019 May 17; 2019 May 17. PMID: 31101824

Polimanti R, Ratanatharathorn A, Maihofer AX, Choi KW, Stein MB, Morey RA, Logue MW, Nievergelt CM, Stein DJ, Koenen KC, Gelernter J, Psychiatric Genomics Consortium Posttraumatic Stress Disorder Working Group.: Association of Economic Status and Educational Attainment With Posttraumatic Stress Disorder: A Mendelian Randomization Study. JAMA Netw Open. 2019 May 3; 2019 May 3. PMID: 31050786

Polimanti R, Peterson RE, Ong JS, MacGregor S, Edwards AC, Clarke TK, Frank J, Gerring Z, Gillespie NA, Lind PA, Maes HH, Martin NG, Mbarek H, Medland SE, Streit F, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium., Agrawal A, Edenberg HJ, Kendler KS, Lewis CM, Sullivan PF, Wray NR, Gelernter J, Derks EM: Evidence of causal effect of major depression on alcohol dependence: findings from the psychiatric genomics consortium. Psychol Med. 2019 May; 2019 Apr 1. PMID: 30929657

Kranzler HR, Zhou H, Kember RL, Vickers Smith R, Justice AC, Damrauer S, Tsao PS, Klarin D, Baras A, Reid J, Overton J, Rader DJ, Cheng Z, Tate JP, Becker WC, Concato J, Xu K, Polimanti R, Zhao H, Gelernter J: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. Nat Commun. 2019 Apr 2; 2019 Apr 2. PMID: 30940813

Montalvo-Ortiz JL, Cheng Z, Kranzler HR, Zhang H, Gelernter J: Genomewide Study of Epigenetic Biomarkers of Opioid Dependence in European- American Women. Sci Rep. 2019 Mar 15; 2019 Mar 15. PMID: 30874594

Jensen KP, Lieberman R, Kranzler HR, Gelernter J, Clinton K, Covault J: Alcohol-responsive genes identified in human iPSC-derived neural cultures. Transl Psychiatry. 2019 Mar 12; 2019 Mar 12. PMID: 30862775

Radhakrishnan K, Aslan M, Harrington KM, Pietrzak RH, Huang G, Muralidhar S, Cho K, Quaden R, Gagnon D, Pyarajan S, Sun N, Zhao H, Gaziano M, Concato J, Stein MB, Gelernter J: Genomics of posttraumatic stress disorder in veterans: Methods and rationale for Veterans Affairs Cooperative Study #575B. Int J Methods Psychiatr Res. 2019 Mar; 2019 Feb 14. PMID: 30767326

Polimanti R, Nuñez YZ, Gelernter J: Increased Risk of Multiple Outpatient Surgeries in African-American Carriers of Transthyretin Val122Ile Mutation Is Modulated by Non-Coding Variants. J Clin Med. 2019 Feb 22; 2019 Feb 22. PMID: 30813263

Levey DF, Polimanti R, Cheng Z, Zhou H, Nuñez YZ, Jain S, He F, Sun X, Ursano RJ, Kessler RC, Smoller JW, Stein MB, Kranzler HR, Gelernter J: Genetic associations with suicide attempt severity and genetic overlap with major depression. Transl Psychiatry. 2019 Jan 17; 2019 Jan 17. PMID: 30655502

Xiang B, Yang BZ, Zhou H, Kranzler H, Gelernter J: GWAS and network analysis of co-occurring nicotine and alcohol dependence identifies significantly associated alleles and network. Am J Med Genet B Neuropsychiatr Genet. 2019 Jan; 2018 Nov 28. PMID: 30488612

Smith AH, Ovesen PL, Skeldal S, Yeo S, Jensen KP, Olsen D, Diazgranados N, Zhao H, Farrer LA, Goldman D, Glerup S, Kranzler HR, Nykjaer A, Gelernter J: Risk Locus Identification Ties Alcohol Withdrawal Symptoms to SORCS2. Alcohol Clin Exp Res. 2018 Dec; 2018 Oct 25. PMID: 30252935

Montalvo-Ortiz JL, Zhou H, D'Andrea I, Maroteaux L, Lori A, Smith A, Ressler KJ, Nuñez YZ, Farrer LA, Zhao H, Kranzler HR, Gelernter J: Translational studies support a role for serotonin 2B receptor (HTR2B) gene in aggression-related cannabis response. Mol Psychiatry. 2018 Dec; 2018 Jun 6. PMID: 29875475

Walters RK, Polimanti R, Johnson EC, McClintick JN, Adams MJ, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Chou YL, Degenhardt F, Docherty AR, Edwards AC, Fontanillas P, Foo JC, Fox L, Frank J, Giegling I, Gordon S, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Herms S, Hodgkinson C, Hoffmann P, Jan Hottenga J, Kennedy MA, Alanne-Kinnunen M, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Pearson JF, Peterson RE, Ripatti S, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG, 23andMe Research Team., Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Elson SL, Frye MA, Gäbel W, Hayward C, Ising M, Keyes M, Kiefer F, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Männistö S, Müller-Myhsok B, Murray AD, Nurnberger JI, Palotie A, Preuss U, Räikkönen K, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt S, Wodarz N, Zill P, Adkins DE, Boden JM, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Cichon S, Costello EJ, de Wit H, Diazgranados N, Dick DM, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono W, Johnson EO, Kaprio JA, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lichtenstein P, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson P, Martin NG, Medland SE, Montgomery GW, Nelson EC, Nöthen MM, Palmer AA, Pedersen NL, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose R, Rujescu D, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Gelernter J, Edenberg HJ, Agrawal A: Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. Nat Neurosci. 2018 Dec; 2018 Nov 26. PMID: 30482948

Cheng Z, Zhou H, Sherva R, Farrer LA, Kranzler HR, Gelernter J: Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans. Biol Psychiatry. 2018 Nov 15; 2018 Jan 11. PMID: 29478698

Kaufman J, Montalvo-Ortiz JL, Holbrook H, O'Loughlin K, Orr C, Kearney C, Yang BZ, Wang T, Zhao H, Althoff R, Garavan H, Gelernter J, Hudziak J: Adverse Childhood Experiences, Epigenetic Measures, and Obesity in Youth. J Pediatr. 2018 Nov; 2018 Aug 31. PMID: 30177354

Zhou H, Cheng Z, Bass N, Krystal JH, Farrer LA, Kranzler HR, Gelernter J: Genome-wide association study identifies glutamate ionotropic receptor GRIA4 as a risk gene for comorbid nicotine dependence and major depression. Transl Psychiatry. 2018 Oct 4; 2018 Oct 4. PMID: 30287806

Kaufman J, Wymbs NF, Montalvo-Ortiz JL, Orr C, Albaugh MD, Althoff R, O'Loughlin K, Holbrook H, Garavan H, Kearney C, Yang BZ, Zhao H, Peña C, Nestler EJ, Lee RS, Mostofsky S, Gelernter J, Hudziak J: Methylation in OTX2 and related genes, maltreatment, and depression in children. Neuropsychopharmacology. 2018 Oct; 2018 Jul 21. PMID: 30089883

Jensen KP, Valentine G, Buta E, DeVito EE, Gelernter J, Sofuoglu M: Biochemical, demographic, and self-reported tobacco-related predictors of the acute heart rate response to nicotine in smokers. Pharmacol Biochem Behav. 2018 Oct; 2018 Aug 11. PMID: 30107183

Ravera S, Carrasco N, Gelernter J, Polimanti R: Phenomic Impact of Genetically-Determined Euthyroid Function and Molecular Differences between Thyroid Disorders. J Clin Med. 2018 Sep 21; 2018 Sep 21. PMID: 30248900

Zheutlin AB, Chekroud AM, Polimanti R, Gelernter J, Sabb FW, Bilder RM, Freimer N, London ED, Hultman CM, Cannon TD: Multivariate Pattern Analysis of Genotype-Phenotype Relationships in Schizophrenia. Schizophr Bull. 2018 Aug 20. PMID: 29534239

Zhang H, Zhou H, Lencz T, Farrer LA, Kranzler HR, Gelernter J: Genome-wide association study of cognitive flexibility assessed by the Wisconsin Card Sorting Test. Am J Med Genet B Neuropsychiatr Genet. 2018 Jul. PMID: 30134085

Gelernter J, Zhou H, Nuñez YZ, Mutirangura A, Malison RT, Kalayasiri R: Genomewide Association Study of Alcohol Dependence and Related Traits in a Thai Population. Alcohol Clin Exp Res. 2018 May; 2018 Mar 13. PMID: 29460428

Polimanti R, Gelernter J, Stein DJ: Genetically determined schizophrenia is not associated with impaired glucose homeostasis. Schizophr Res. 2018 May; 2017 Oct 29. PMID: 29092750

Polimanti R, Kayser MH, Gelernter J: Local adaptation in European populations affected the genetics of psychiatric disorders and behavioral traits. Genome Med. 2018 Mar 26; 2018 Mar 26. PMID: 29580271

Polimanti R, Gelernter J: ADH1B: From alcoholism, natural selection, and cancer to the human phenome. Am J Med Genet B Neuropsychiatr Genet. 2018 Mar; 2017 Mar 27. PMID: 28349588

Polimanti R, Kaufman J, Zhao H, Kranzler HR, Ursano RJ, Kessler RC, Stein MB, Gelernter J: Trauma exposure interacts with the genetic risk of bipolar disorder in alcohol misuse of US soldiers. Acta Psychiatr Scand. 2018 Feb; 2017 Dec 11. PMID: 29230810

Mota NP, Han S, Harpaz-Rotem I, Maruff P, Krystal JH, Southwick SM, Gelernter J, Pietrzak RH: Apolipoprotein E gene polymorphism, trauma burden, and posttraumatic stress symptoms in U.S. military veterans: Results from the National Health and Resilience in Veterans Study. Depress Anxiety. 2018 Feb; 2017 Nov 24. PMID: 29172227

Montalvo-Ortiz JL, Zhang H, Chen C, Liu C, Coccaro EF: Genome-Wide DNA Methylation Changes Associated with Intermittent Explosive Disorder: A Gene-Based Functional Enrichment Analysis. Int J Neuropsychopharmacol. 2018 Jan 1. PMID: 29106553

Polimanti R, Kaufman J, Zhao H, Kranzler HR, Ursano RJ, Kessler RC, Gelernter J, Stein MB: A genome-wide gene-by-trauma interaction study of alcohol misuse in two independent cohorts identifies PRKG1 as a risk locus. Mol Psychiatry. 2018 Jan; 2017 Mar 7. PMID: 28265120

Yang BZ, Arias AJ, Feinn R, Krystal JH, Gelernter J, Petrakis IL: GRIK1 and GABRA2 Variants Have Distinct Effects on the Dose-Related Subjective Response to Intravenous Alcohol in Healthy Social Drinkers. Alcohol Clin Exp Res. 2017 Dec; 2017 Nov 13. PMID: 29131352

Polimanti R, Zhao H, Farrer LA, Kranzler HR, Gelernter J: Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors. Am J Med Genet B Neuropsychiatr Genet. 2017 Dec; 2017 Oct 9. PMID: 28990359

Zhou H, Polimanti R, Yang BZ, Wang Q, Han S, Sherva R, Nuñez YZ, Zhao H, Farrer LA, Kranzler HR, Gelernter J: Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression. JAMA Psychiatry. 2017 Dec 1. PMID: 29071344

Polimanti R, Amstadter AB, Stein MB, Almli LM, Baker DG, Bierut LJ, Bradley B, Farrer LA, Johnson EO, King A, Kranzler HR, Maihofer AX, Rice JP, Roberts AL, Saccone NL, Zhao H, Liberzon I, Ressler KJ, Nievergelt CM, Koenen KC, Gelernter J, Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup.: A putative causal relationship between genetically determined female body shape and posttraumatic stress disorder. Genome Med. 2017 Nov 27; 2017 Nov 27. PMID: 29178946

Sippel LM, Han S, Watkins LE, Harpaz-Rotem I, Southwick SM, Krystal JH, Olff M, Sherva R, Farrer LA, Kranzler HR, Gelernter J, Pietrzak RH: Oxytocin receptor gene polymorphisms, attachment, and PTSD: Results from the National Health and Resilience in Veterans Study. J Psychiatr Res. 2017 Nov; 2017 Jul 8. PMID: 28715704

Andersen AM, Pietrzak RH, Kranzler HR, Ma L, Zhou H, Liu X, Kramer J, Kuperman S, Edenberg HJ, Nurnberger JI Jr, Rice JP, Tischfield JA, Goate A, Foroud TM, Meyers JL, Porjesz B, Dick DM, Hesselbrock V, Boerwinkle E, Southwick SM, Krystal JH, Weissman MM, Levinson DF, Potash JB, Gelernter J, Han S: Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence. JAMA Psychiatry. 2017 Nov 1. PMID: 28813562

Tamman AJF, Sippel LM, Han S, Neria Y, Krystal JH, Southwick SM, Gelernter J, Pietrzak RH: Attachment style moderates effects of FKBP5 polymorphisms and childhood abuse on post-traumatic stress symptoms: Results from the National Health and Resilience in Veterans Study. World J Biol Psychiatry. 2017 Oct 5; 2017 Oct 5. PMID: 28891785

Watkins LE, Han S, Krystal JH, Southwick SM, Gelernter J, Pietrzak RH: Association Between Functional Polymorphism in Neuropeptide Y Gene Promoter rs16147 and Resilience to Traumatic Stress in US Military Veterans. J Clin Psychiatry. 2017 Sep/Oct. PMID: 29099554

Lippard ETC, Jensen KP, Wang F, Johnston JAY, Spencer L, Pittman B, Gelernter J, Blumberg HP: Genetic variation of ANK3 is associated with lower white matter structural integrity in bipolar disorder. Mol Psychiatry. 2017 Sep. PMID: 28831200

Lippard ETC, Jensen KP, Wang F, Johnston JAY, Spencer L, Pittman B, Gelernter J, Blumberg HP: Effects of ANK3 variation on gray and white matter in bipolar disorder. Mol Psychiatry. 2017 Sep; 2016 May 31. PMID: 27240527

Zhang H, Gelernter J: Review: DNA methylation and alcohol use disorders: Progress and challenges. Am J Addict. 2017 Aug; 2016 Oct 19. PMID: 27759945

Stein MB, Chen CY, Jain S, Jensen KP, He F, Heeringa SG, Kessler RC, Maihofer A, Nock MK, Ripke S, Sun X, Thomas ML, Ursano RJ, Smoller JW, Gelernter J, Army STARRS Collaborators.: Genetic risk variants for social anxiety. Am J Med Genet B Neuropsychiatr Genet. 2017 Jun; 2017 Apr 27. PMID: 28512750

Polimanti R, Meda SA, Pearlson GD, Zhao H, Sherva R, Farrer LA, Kranzler HR, Gelernter J: S100A10 identified in a genome-wide gene × cannabis dependence interaction analysis of risky sexual behaviours. J Psychiatry Neurosci. 2017 Jun. PMID: 28418321

Polimanti R, Jensen KP, Gelernter J: Phenome-wide association study for CYP2A6 alleles: rs113288603 is associated with hearing loss symptoms in elderly smokers. Sci Rep. 2017 Apr 21; 2017 Apr 21. PMID: 28432340

Yang BZ, Han S, Kranzler HR, Palmer AA, Gelernter J: Sex-specific linkage scans in opioid dependence. Am J Med Genet B Neuropsychiatr Genet. 2017 Apr; 2016 Oct 20. PMID: 27762075

Polimanti R, Agrawal A, Gelernter J: Schizophrenia and substance use comorbidity: a genome-wide perspective. Genome Med. 2017 Mar 21; 2017 Mar 21. PMID: 28327175

Polimanti R, Zhang H, Smith AH, Zhao H, Farrer LA, Kranzler HR, Gelernter J: Genome-wide association study of body mass index in subjects with alcohol dependence. Addict Biol. 2017 Mar; 2015 Oct 12. PMID: 26458734

Stein MB, Chen CY, Jain S, Jensen KP, He F, Heeringa SG, Kessler RC, Maihofer A, Nock MK, Ripke S, Sun X, Thomas ML, Ursano RJ, Smoller JW, Gelernter J, Army STARRS Collaborators.: Genetic risk variants for social anxiety. Am J Med Genet B Neuropsychiatr Genet. 2017 Mar. PMID: 28224735

Smith AH, Jensen KP, Li J, Nunez Y, Farrer LA, Hakonarson H, Cook-Sather SD, Kranzler HR, Gelernter J: Genome-wide association study of therapeutic opioid dosing identifies a novel locus upstream of OPRM1. Mol Psychiatry. 2017 Mar; 2017 Jan 24. PMID: 28115739

Polimanti R, Chen CY, Ursano RJ, Heeringa SG, Jain S, Kessler RC, Nock MK, Smoller JW, Sun X, Gelernter J, Stein MB: Cross-Phenotype Polygenic Risk Score Analysis of Persistent Post-Concussive Symptoms in U.S. Army Soldiers with Deployment-Acquired Traumatic Brain Injury. J Neurotrauma. 2017 Feb 15; 2016 Aug 25. PMID: 27439997

Polimanti R, Gelernter J: Widespread signatures of positive selection in common risk alleles associated to autism spectrum disorder. PLoS Genet. 2017 Feb; 2017 Feb 10. PMID: 28187187

Xu H, Wang F, Kranzler HR, Gelernter J, Zhang H: Alcohol and nicotine codependence-associated DNA methylation changes in promoter regions of addiction-related genes. Sci Rep. 2017 Feb 6; 2017 Feb 6. PMID: 28165486

Jensen KP, Smith AH, Herman AI, Farrer LA, Kranzler HR, Sofuoglu M, Gelernter J: A protocadherin gene cluster regulatory variant is associated with nicotine withdrawal and the urge to smoke. Mol Psychiatry. 2017 Feb; 2016 Apr 12. PMID: 27067016

Polimanti R, Wang Q, Meda SA, Patel KT, Pearlson GD, Zhao H, Farrer LA, Kranzler HR, Gelernter J: The Interplay Between Risky Sexual Behaviors and Alcohol Dependence: Genome-Wide Association and Neuroimaging Support for LHPP as a Risk Gene. Neuropsychopharmacology. 2017 Feb; 2016 Aug 17. PMID: 27531626

Wang Q, Polimanti R, Kranzler HR, Farrer LA, Zhao H, Gelernter J: Genetic factor common to schizophrenia and HIV infection is associated with risky sexual behavior: antagonistic vs. synergistic pleiotropic SNPs enriched for distinctly different biological functions. Hum Genet. 2017 Jan; 2016 Oct 17. PMID: 27752767

Montalvo-Ortiz JL, Bordner KA, Carlyle BC, Gelernter J, Simen AA, Kaufman J: The role of genes involved in stress, neural plasticity, and brain circuitry in depressive phenotypes: Convergent findings in a mouse model of neglect. Behav Brain Res. 2016 Dec 15; 2016 Aug 6. PMID: 27506655

Polimanti R, Kranzler HR, Gelernter J: Phenome-Wide Association Study for Alcohol and Nicotine Risk Alleles in 26394 Women. Neuropsychopharmacology. 2016 Oct; 2016 May 17. PMID: 27187070

Agrawal A, Edenberg HJ, Gelernter J: Meta-Analyses of Genome-Wide Association Data Hold New Promise for Addiction Genetics. J Stud Alcohol Drugs. 2016 Sep. PMID: 27588522

Esterlis I, Hillmer AT, Bois F, Pittman B, McGovern E, O'Malley SS, Picciotto MR, Yang BZ, Gelernter J, Cosgrove KP: CHRNA4 and ANKK1 Polymorphisms Influence Smoking-Induced Nicotinic Acetylcholine Receptor Upregulation. Nicotine Tob Res. 2016 Sep; 2016 Mar 31. PMID: 27611310

Polimanti R, Yang BZ, Zhao H, Gelernter J: Evidence of Polygenic Adaptation in the Systems Genetics of Anthropometric Traits. PLoS One. 2016; 2016 Aug 18. PMID: 27537407

Stein MB, Chen CY, Ursano RJ, Cai T, Gelernter J, Heeringa SG, Jain S, Jensen KP, Maihofer AX, Mitchell C, Nievergelt CM, Nock MK, Neale BM, Polimanti R, Ripke S, Sun X, Thomas ML, Wang Q, Ware EB, Borja S, Kessler RC, Smoller JW, Army Study to Assess Risk and Resilience in Servicemembers (STARRS) Collaborators.: Genome-wide Association Studies of Posttraumatic Stress Disorder in 2 Cohorts of US Army Soldiers. JAMA Psychiatry. 2016 Jul 1. PMID: 27167565

Watkins LE, Han S, Harpaz-Rotem I, Mota NP, Southwick SM, Krystal JH, Gelernter J, Pietrzak RH: FKBP5 polymorphisms, childhood abuse, and PTSD symptoms: Results from the National Health and Resilience in Veterans Study. Psychoneuroendocrinology. 2016 Jul; 2016 Apr 5. PMID: 27078785

Sherva R, Wang Q, Kranzler H, Zhao H, Koesterer R, Herman A, Farrer LA, Gelernter J: Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks. JAMA Psychiatry. 2016 May 1. PMID: 27028160

Clarke TK, Smith AH, Gelernter J, Kranzler HR, Farrer LA, Hall LS, Fernandez-Pujals AM, MacIntyre DJ, Smith BH, Hocking LJ, Padmanabhan S, Hayward C, Thomson PA, Porteous DJ, Deary IJ, McIntosh AM: Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort. Addict Biol. 2016 Mar; 2015 Apr 10. PMID: 25865819

Schwantes-An TH, Zhang J, Chen LS, Hartz SM, Culverhouse RC, Chen X, Coon H, Frank J, Kamens HM, Konte B, Kovanen L, Latvala A, Legrand LN, Maher BS, Melroy WE, Nelson EC, Reid MW, Robinson JD, Shen PH, Yang BZ, Andrews JA, Aveyard P, Beltcheva O, Brown SA, Cannon DS, Cichon S, Corley RP, Dahmen N, Degenhardt L, Foroud T, Gaebel W, Giegling I, Glatt SJ, Grucza RA, Hardin J, Hartmann AM, Heath AC, Herms S, Hodgkinson CA, Hoffmann P, Hops H, Huizinga D, Ising M, Johnson EO, Johnstone E, Kaneva RP, Kendler KS, Kiefer F, Kranzler HR, Krauter KS, Levran O, Lucae S, Lynskey MT, Maier W, Mann K, Martin NG, Mattheisen M, Montgomery GW, Müller-Myhsok B, Murphy MF, Neale MC, Nikolov MA, Nishita D, Nöthen MM, Nurnberger J, Partonen T, Pergadia ML, Reynolds M, Ridinger M, Rose RJ, Rouvinen-Lagerström N, Scherbaum N, Schmäl C, Soyka M, Stallings MC, Steffens M, Treutlein J, Tsuang M, Wall TL, Wodarz N, Yuferov V, Zill P, Bergen AW, Chen J, Cinciripini PM, Edenberg HJ, Ehringer MA, Ferrell RE, Gelernter J, Goldman D, Hewitt JK, Hopfer CJ, Iacono WG, Kaprio J, Kreek MJ, Kremensky IM, Madden PA, McGue M, Munafò MR, Philibert RA, Rietschel M, Roy A, Rujescu D, Saarikoski ST, Swan GE, Todorov AA, Vanyukov MM, Weiss RB, Bierut LJ, Saccone NL: Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts. Behav Genet. 2016 Mar; 2015 Sep 21. PMID: 26392368

Wang F, Xu H, Zhao H, Gelernter J, Zhang H: DNA co-methylation modules in postmortem prefrontal cortex tissues of European Australians with alcohol use disorders. Sci Rep. 2016 Jan 14; 2016 Jan 14. PMID: 26763658

Montalvo-Ortiz JL, Gelernter J, Hudziak J, Kaufman J: RDoC and translational perspectives on the genetics of trauma-related psychiatric disorders. Am J Med Genet B Neuropsychiatr Genet. 2016 Jan; 2015 Nov 22. PMID: 26592203

Sulovari A, Kranzler HR, Farrer LA, Gelernter J, Li D: Further analyses support the association between light eye color and alcohol dependence. Am J Med Genet B Neuropsychiatr Genet. 2015 Dec; 2015 Aug 20. PMID: 26290254

Wang Q, Yang C, Gelernter J, Zhao H: Pervasive pleiotropy between psychiatric disorders and immune disorders revealed by integrative analysis of multiple GWAS. Hum Genet. 2015 Nov; 2015 Sep 4. PMID: 26340901

Jensen KP, DeVito EE, Herman AI, Valentine GW, Gelernter J, Sofuoglu M: A CHRNA5 Smoking Risk Variant Decreases the Aversive Effects of Nicotine in Humans. Neuropsychopharmacology. 2015 Nov; 2015 May 7. PMID: 25948103

Xiang Y, Kim KY, Gelernter J, Park IH, Zhang H: Ethanol upregulates NMDA receptor subunit gene expression in human embryonic stem cell-derived cortical neurons. PLoS One. 2015; 2015 Aug 12. PMID: 26266540

Jensen KP, Herman AI, Morean ME, Kranzler HR, Gelernter J, Sofuoglu M: FKBP5 variation is associated with the acute and chronic effects of nicotine. Pharmacogenomics J. 2015 Aug; 2014 Dec 23. PMID: 25532758

Xu K, Kranzler HR, Sherva R, Sartor CE, Almasy L, Koesterer R, Zhao H, Farrer LA, Gelernter J: Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans. Alcohol Clin Exp Res. 2015 Jul; 2015 Jun 3. PMID: 26036284

Sulovari A, Kranzler HR, Farrer LA, Gelernter J, Li D: Eye color: A potential indicator of alcohol dependence risk in European Americans. Am J Med Genet B Neuropsychiatr Genet. 2015 Jul; 2015 Apr 29. PMID: 25921801

Vongpaisarnsin K, Listman JB, Malison RT, Gelernter J: Ancestry informative markers for distinguishing between Thai populations based on genome-wide association datasets. Leg Med (Tokyo). 2015 Jul; 2015 Feb 25. PMID: 25759192

Gelernter J, Kranzler HR, Sherva R, Almasy L, Herman AI, Koesterer R, Zhao H, Farrer LA: Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans. Biol Psychiatry. 2015 Mar 1; 2014 Sep 16. PMID: 25555482

Li D, Zhao H, Kranzler HR, Li MD, Jensen KP, Zayats T, Farrer LA, Gelernter J: Genome-wide association study of copy number variations (CNVs) with opioid dependence. Neuropsychopharmacology. 2015 Mar; 2014 Sep 27. PMID: 25345593

Gelernter J: Genetics of complex traits in psychiatry. Biol Psychiatry. 2015 Jan 1; 2014 Aug 13. PMID: 25444161

Polimanti R, Yang C, Zhao H, Gelernter J: Dissecting ancestry genomic background in substance dependence genome-wide association studies. Pharmacogenomics. 2015; 2015 Aug 12. PMID: 26267224

Sartor CE, Wang Z, Xu K, Kranzler HR, Gelernter J: The joint effects of ADH1B variants and childhood adversity on alcohol related phenotypes in African-American and European-American women and men. Alcohol Clin Exp Res. 2014 Dec; 2014 Nov 19. PMID: 25410943

Chung D, Yang C, Li C, Gelernter J, Zhao H: GPA: a statistical approach to prioritizing GWAS results by integrating pleiotropy and annotation. PLoS Genet. 2014 Nov; 2014 Nov 13. PMID: 25393678

Zhang H, Wang F, Xu H, Liu Y, Liu J, Zhao H, Gelernter J: Differentially co-expressed genes in postmortem prefrontal cortex of individuals with alcohol use disorders: influence on alcohol metabolism-related pathways. Hum Genet. 2014 Nov; 2014 Jul 30. PMID: 25073604

Khadka S, Narayanan B, Meda SA, Gelernter J, Han S, Sawyer B, Aslanzadeh F, Stevens MC, Hawkins KA, Anticevic A, Potenza MN, Pearlson GD: Genetic association of impulsivity in young adults: a multivariate study. Transl Psychiatry. 2014 Sep 30; 2014 Sep 30. PMID: 25268255

Xie P, Kranzler HR, Krystal JH, Farrer LA, Zhao H, Gelernter J: Deep resequencing of 17 glutamate system genes identifies rare variants in DISC1 and GRIN2B affecting risk of opioid dependence. Addict Biol. 2014 Sep; 2013 Jul 16. PMID: 23855403

Zhang H, Wang F, Kranzler HR, Yang C, Xu H, Wang Z, Zhao H, Gelernter J: Identification of methylation quantitative trait loci (mQTLs) influencing promoter DNA methylation of alcohol dependence risk genes. Hum Genet. 2014 Sep; 2014 Jun 3. PMID: 24889829

Gelernter J, Kranzler HR, Sherva R, Koesterer R, Almasy L, Zhao H, Farrer LA: Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways. Biol Psychiatry. 2014 Jul 1; 2013 Oct 19. PMID: 24143882

Gelernter J, Sherva R, Koesterer R, Almasy L, Zhao H, Kranzler HR, Farrer L: Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene. Mol Psychiatry. 2014 Jun; 2013 Aug 20. PMID: 23958962

Levey DF, Le-Niculescu H, Frank J, Ayalew M, Jain N, Kirlin B, Learman R, Winiger E, Rodd Z, Shekhar A, Schork N, Kiefer F, Wodarz N, Müller-Myhsok B, Dahmen N, GESGA Consortium., Nöthen M, Sherva R, Farrer L, Smith AH, Kranzler HR, Rietschel M, Gelernter J, Niculescu AB: Genetic risk prediction and neurobiological understanding of alcoholism. Transl Psychiatry. 2014 May 20; 2014 May 20. PMID: 24844177

Li C, Yang C, Gelernter J, Zhao H: Improving genetic risk prediction by leveraging pleiotropy. Hum Genet. 2014 May; 2013 Dec 13. PMID: 24337655

Yang C, Li C, Kranzler HR, Farrer LA, Zhao H, Gelernter J: Exploring the genetic architecture of alcohol dependence in African-Americans via analysis of a genomewide set of common variants. Hum Genet. 2014 May; 2013 Dec 3. PMID: 24297757

Sartor CE, Kranzler HR, Gelernter J: Characteristics and course of dependence in cocaine-dependent individuals who never used alcohol or marijuana or used cocaine first. J Stud Alcohol Drugs. 2014 May. PMID: 24766754

Gelernter J: SLC6A4 polymorphism, population genetics, and psychiatric traits. Hum Genet. 2014 Apr; 2014 Jan 3. PMID: 24385047

Weder N, Zhang H, Jensen K, Yang BZ, Simen A, Jackowski A, Lipschitz D, Douglas-Palumberi H, Ge M, Perepletchikova F, O'Loughlin K, Hudziak JJ, Gelernter J, Kaufman J: Child abuse, depression, and methylation in genes involved with stress, neural plasticity, and brain circuitry. J Am Acad Child Adolesc Psychiatry. 2014 Apr; 2014 Jan 27. PMID: 24655651

Jensen KP, Kranzler HR, Stein MB, Gelernter J: The effects of a MAP2K5 microRNA target site SNP on risk for anxiety and depressive disorders. Am J Med Genet B Neuropsychiatr Genet. 2014 Mar; 2014 Jan 16. PMID: 24436253

Quillen EE, Chen XD, Almasy L, Yang F, He H, Li X, Wang XY, Liu TQ, Hao W, Deng HW, Kranzler HR, Gelernter J: ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample. Am J Med Genet B Neuropsychiatr Genet. 2014 Mar; 2013 Nov 26. PMID: 24277619

Xu H, Wang F, Liu Y, Yu Y, Gelernter J, Zhang H: Sex-biased methylome and transcriptome in human prefrontal cortex. Hum Mol Genet. 2014 Mar 1; 2013 Oct 24. PMID: 24163133

McClure-Begley TD, Papke RL, Stone KL, Stokes C, Levy AD, Gelernter J, Xie P, Lindstrom J, Picciotto MR: Rare human nicotinic acetylcholine receptor α4 subunit (CHRNA4) variants affect expression and function of high-affinity nicotinic acetylcholine receptors. J Pharmacol Exp Ther. 2014 Mar; 2014 Jan 2. PMID: 24385388

Li D, Sulovari A, Cheng C, Zhao H, Kranzler HR, Gelernter J: Association of gamma-aminobutyric acid A receptor α2 gene (GABRA2) with alcohol use disorder. Neuropsychopharmacology. 2014 Mar; 2013 Oct 18. PMID: 24136292

Sartor CE, Kranzler HR, Gelernter J: Rate of progression from first use to dependence on cocaine or opioids: a cross-substance examination of associated demographic, psychiatric, and childhood risk factors. Addict Behav. 2014 Feb; 2013 Oct 18. PMID: 24238782

Jensen KP, Stein MB, Kranzler HR, Yang BZ, Farrer LA, Gelernter J: The α-endomannosidase gene (MANEA) is associated with panic disorder and social anxiety disorder. Transl Psychiatry. 2014 Jan 28; 2014 Jan 28. PMID: 24473444

Gelernter J, Kranzler HR, Sherva R, Almasy L, Koesterer R, Smith AH, Anton R, Preuss UW, Ridinger M, Rujescu D, Wodarz N, Zill P, Zhao H, Farrer LA: Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci. Mol Psychiatry. 2014 Jan; 2013 Oct 29. PMID: 24166409

Han S, Yang BZ, Kranzler HR, Liu X, Zhao H, Farrer LA, Boerwinkle E, Potash JB, Gelernter J: Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence. Am J Hum Genet. 2013 Dec 5; 2013 Nov 21. PMID: 24268660

Stephens SH, Hartz SM, Hoft NR, Saccone NL, Corley RC, Hewitt JK, Hopfer CJ, Breslau N, Coon H, Chen X, Ducci F, Dueker N, Franceschini N, Frank J, Han Y, Hansel NN, Jiang C, Korhonen T, Lind PA, Liu J, Lyytikäinen LP, Michel M, Shaffer JR, Short SE, Sun J, Teumer A, Thompson JR, Vogelzangs N, Vink JM, Wenzlaff A, Wheeler W, Yang BZ, Aggen SH, Balmforth AJ, Baumeister SE, Beaty TH, Benjamin DJ, Bergen AW, Broms U, Cesarini D, Chatterjee N, Chen J, Cheng YC, Cichon S, Couper D, Cucca F, Dick D, Foroud T, Furberg H, Giegling I, Gillespie NA, Gu F, Hall AS, Hällfors J, Han S, Hartmann AM, Heikkilä K, Hickie IB, Hottenga JJ, Jousilahti P, Kaakinen M, Kähönen M, Koellinger PD, Kittner S, Konte B, Landi MT, Laatikainen T, Leppert M, Levy SM, Mathias RA, McNeil DW, Medland SE, Montgomery GW, Murray T, Nauck M, North KE, Paré PD, Pergadia M, Ruczinski I, Salomaa V, Viikari J, Willemsen G, Barnes KC, Boerwinkle E, Boomsma DI, Caporaso N, Edenberg HJ, Francks C, Gelernter J, Grabe HJ, Hops H, Jarvelin MR, Johannesson M, Kendler KS, Lehtimäki T, Magnusson PK, Marazita ML, Marchini J, Mitchell BD, Nöthen MM, Penninx BW, Raitakari O, Rietschel M, Rujescu D, Samani NJ, Schwartz AG, Shete S, Spitz M, Swan GE, Völzke H, Veijola J, Wei Q, Amos C, Cannon DS, Grucza R, Hatsukami D, Heath A, Johnson EO, Kaprio J, Madden P, Martin NG, Stevens VL, Weiss RB, Kraft P, Bierut LJ, Ehringer MA: Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking. Genet Epidemiol. 2013 Dec; 2013 Nov 1. PMID: 24186853

Wang LS, Jiao Y, Huang Y, Liu XY, Gibson G, Bennett B, Hamre KM, Li DW, Zhao HY, Gelernter J, Kranzler HR, Farrer LA, Lu L, Wang YJ, Gu WK: Critical evaluation of transcription factor Atf2 as a candidate modulator of alcohol preference in mouse and human populations. Genet Mol Res. 2013 Nov 26; 2013 Nov 26. PMID: 24338393

Xie P, Kranzler HR, Yang C, Zhao H, Farrer LA, Gelernter J: Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. Biol Psychiatry. 2013 Nov 1; 2013 May 28. PMID: 23726511

Amstadter AB, Sumner JA, Acierno R, Ruggiero KJ, Koenen KC, Kilpatrick DG, Galea S, Gelernter J: Support for association of RORA variant and post traumatic stress symptoms in a population-based study of hurricane exposed adults. Mol Psychiatry. 2013 Nov; 2013 Jan 15. PMID: 23319003

Liu X, Han S, Wang Z, Gelernter J, Yang BZ: Variant callers for next-generation sequencing data: a comparison study. PLoS One. 2013; 2013 Sep 27. PMID: 24086590

Wang Z, Liu X, Yang BZ, Gelernter J: The role and challenges of exome sequencing in studies of human diseases. Front Genet. 2013 Aug 26; 2013 Aug 26. PMID: 24032039

Wang F, Gelernter J, Zhang H: Differential Expression of miR-130a in Postmortem Prefrontal Cortex of Subjects with Alcohol Use Disorders. J Addict Res Ther. 2013 Jul 23. PMID: 25383235

Zhang H, Wang F, Kranzler HR, Zhao H, Gelernter J: Profiling of childhood adversity-associated DNA methylation changes in alcoholic patients and healthy controls. PLoS One. 2013; 2013 Jun 14. PMID: 23799031

Pietrzak RH, Galea S, Southwick SM, Gelernter J: Examining the relation between the serotonin transporter 5-HTTPLR genotype x trauma exposure interaction on a contemporary phenotypic model of posttraumatic stress symptomatology: a pilot study. J Affect Disord. 2013 May 15; 2012 Nov 24. PMID: 23183127

Han S, Gelernter J, Kranzler HR, Yang BZ: Ordered subset linkage analysis based on admixture proportion identifies new linkage evidence for alcohol dependence in African-Americans. Hum Genet. 2013 Apr; 2012 Dec 13. PMID: 23239122

Yang BZ, Zhang H, Ge W, Weder N, Douglas-Palumberi H, Perepletchikova F, Gelernter J, Kaufman J: Child abuse and epigenetic mechanisms of disease risk. Am J Prev Med. 2013 Feb. PMID: 23332324

Zhang H, Herman AI, Kranzler HR, Anton RF, Zhao H, Zheng W, Gelernter J: Array-based profiling of DNA methylation changes associated with alcohol dependence. Alcohol Clin Exp Res. 2013 Jan; 2012 Aug 24. PMID: 22924764

Zayats T, Yang BZ, Xie P, Poling J, Farrer LA, Gelernter J: A complex interplay between personality domains, marital status and a variant in CHRNA5 on the risks of cocaine, nicotine dependences and cocaine-induced paranoia. PLoS One. 2013; 2013 Jan 7. PMID: 23308091

Han S, Yang BZ, Kranzler HR, Oslin D, Anton R, Farrer LA, Gelernter J: Linkage analysis followed by association show NRG1 associated with cannabis dependence in African Americans. Biol Psychiatry. 2012 Oct 15; 2012 Apr 19. PMID: 22520967

Zhang H, Herman AI, Kranzler HR, Anton RF, Simen AA, Gelernter J: Hypermethylation of OPRM1 promoter region in European Americans with alcohol dependence. J Hum Genet. 2012 Oct; 2012 Aug 23. PMID: 22914673

Bauer LO, Yang BZ, Houston RJ, Kranzler HR, Gelernter J: GABRA2 genotype, impulsivity, and body mass. Am J Addict. 2012 Sep-Oct. PMID: 22882390

Xie P, Kranzler HR, Farrer L, Gelernter J: Serotonin transporter 5-HTTLPR genotype moderates the effects of childhood adversity on posttraumatic stress disorder risk: a replication study. Am J Med Genet B Neuropsychiatr Genet. 2012 Sep; 2012 Jun 12. PMID: 22693124

Hartz SM, Short SE, Saccone NL, Culverhouse R, Chen L, Schwantes-An TH, Coon H, Han Y, Stephens SH, Sun J, Chen X, Ducci F, Dueker N, Franceschini N, Frank J, Geller F, Gubjartsson D, Hansel NN, Jiang C, Keskitalo-Vuokko K, Liu Z, Lyytikäinen LP, Michel M, Rawal R, Rosenberger A, Scheet P, Shaffer JR, Teumer A, Thompson JR, Vink JM, Vogelzangs N, Wenzlaff AS, Wheeler W, Xiao X, Yang BZ, Aggen SH, Balmforth AJ, Baumeister SE, Beaty T, Bennett S, Bergen AW, Boyd HA, Broms U, Campbell H, Chatterjee N, Chen J, Cheng YC, Cichon S, Couper D, Cucca F, Dick DM, Foroud T, Furberg H, Giegling I, Gu F, Hall AS, Hällfors J, Han S, Hartmann AM, Hayward C, Heikkilä K, Hewitt JK, Hottenga JJ, Jensen MK, Jousilahti P, Kaakinen M, Kittner SJ, Konte B, Korhonen T, Landi MT, Laatikainen T, Leppert M, Levy SM, Mathias RA, McNeil DW, Medland SE, Montgomery GW, Muley T, Murray T, Nauck M, North K, Pergadia M, Polasek O, Ramos EM, Ripatti S, Risch A, Ruczinski I, Rudan I, Salomaa V, Schlessinger D, Styrkársdóttir U, Terracciano A, Uda M, Willemsen G, Wu X, Abecasis G, Barnes K, Bickeböller H, Boerwinkle E, Boomsma DI, Caporaso N, Duan J, Edenberg HJ, Francks C, Gejman PV, Gelernter J, Grabe HJ, Hops H, Jarvelin MR, Viikari J, Kähönen M, Kendler KS, Lehtimäki T, Levinson DF, Marazita ML, Marchini J, Melbye M, Mitchell BD, Murray JC, Nöthen MM, Penninx BW, Raitakari O, Rietschel M, Rujescu D, Samani NJ, Sanders AR, Schwartz AG, Shete S, Shi J, Spitz M, Stefansson K, Swan GE, Thorgeirsson T, Völzke H, Wei Q, Wichmann HE, Amos CI, Breslau N, Cannon DS, Ehringer M, Grucza R, Hatsukami D, Heath A, Johnson EO, Kaprio J, Madden P, Martin NG, Stevens VL, Stitzel JA, Weiss RB, Kraft P, Bierut LJ: Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. Arch Gen Psychiatry. 2012 Aug. PMID: 22868939

Li D, Zhao H, Gelernter J: Further clarification of the contribution of the ADH1C gene to vulnerability of alcoholism and selected liver diseases. Hum Genet. 2012 Aug; 2012 Apr 5. PMID: 22476623

Yang BZ, Han S, Kranzler HR, Farrer LA, Elston RC, Gelernter J: Autosomal linkage scan for loci predisposing to comorbid dependence on multiple substances. Am J Med Genet B Neuropsychiatr Genet. 2012 Jun; 2012 Feb 21. PMID: 22354695

Bauer LO, Covault J, Gelernter J: GABRA2 and KIBRA genotypes predict early relapse to substance use. Drug Alcohol Depend. 2012 Jun 1; 2011 Nov 29. PMID: 22129841

Zhang H, Wang F, Kranzler HR, Anton RF, Gelernter J: Variation in regulator of G-protein signaling 17 gene (RGS17) is associated with multiple substance dependence diagnoses. Behav Brain Funct. 2012 May 16; 2012 May 16. PMID: 22591552

Li D, Zhao H, Gelernter J: Strong protective effect of the aldehyde dehydrogenase gene (ALDH2) 504lys (*2) allele against alcoholism and alcohol-induced medical diseases in Asians. Hum Genet. 2012 May; 2011 Nov 20. PMID: 22102315

Li D, Zhao H, Kranzler HR, Oslin D, Anton RF, Farrer LA, Gelernter J: Association of COL25A1 with comorbid antisocial personality disorder and substance dependence. Biol Psychiatry. 2012 Apr 15; 2012 Jan 31. PMID: 22297151

Ittiwut C, Yang BZ, Kranzler HR, Anton RF, Hirunsatit R, Weiss RD, Covault J, Farrer LA, Gelernter J: GABRG1 and GABRA2 variation associated with alcohol dependence in African Americans. Alcohol Clin Exp Res. 2012 Apr; 2011 Sep 15. PMID: 21919924

Chang SC, Xie P, Anton RF, De Vivo I, Farrer LA, Kranzler HR, Oslin D, Purcell SM, Roberts AL, Smoller JW, Uddin M, Gelernter J, Koenen KC: No association between ADCYAP1R1 and post-traumatic stress disorder in two independent samples. Mol Psychiatry. 2012 Mar; 2011 Sep 13. PMID: 21912390

Xie P, Kranzler HR, Zhang H, Oslin D, Anton RF, Farrer LA, Gelernter J: Childhood adversity increases risk for nicotine dependence and interacts with α5 nicotinic acetylcholine receptor genotype specifically in males. Neuropsychopharmacology. 2012 Feb; 2011 Oct 19. PMID: 22012472

Wang F, Gelernter J, Kranzler HR, Zhang H: Identification of POMC exonic variants associated with substance dependence and body mass index. PLoS One. 2012; 2012 Sep 17. PMID: 23028917

Kranzler HR, Feinn R, Nelson EC, Covault J, Anton RF, Farrer L, Gelernter J: A CRHR1 haplotype moderates the effect of adverse childhood experiences on lifetime risk of major depressive episode in African-American women. Am J Med Genet B Neuropsychiatr Genet. 2011 Dec; 2011 Oct 13. PMID: 21998007

Yang BZ, Han S, Kranzler HR, Farrer LA, Gelernter J: A genomewide linkage scan of cocaine dependence and major depressive episode in two populations. Neuropsychopharmacology. 2011 Nov; 2011 Aug 17. PMID: 21849985

Xie P, Kranzler HR, Krauthammer M, Cosgrove KP, Oslin D, Anton RF, Farrer LA, Picciotto MR, Krystal JH, Zhao H, Gelernter J: Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence. Biol Psychiatry. 2011 Sep 15; 2011 Jun 17. PMID: 21683344

Li D, Zhao H, Gelernter J: Strong association of the alcohol dehydrogenase 1B gene (ADH1B) with alcohol dependence and alcohol-induced medical diseases. Biol Psychiatry. 2011 Sep 15; 2011 Apr 17. PMID: 21497796

Ittiwut R, Listman JB, Ittiwut C, Cubells JF, Weiss RD, Brady K, Oslin D, Farrer LA, Kranzler HR, Gelernter J: Association between polymorphisms in catechol-O-methyltransferase (COMT) and cocaine-induced paranoia in European-American and African-American populations. Am J Med Genet B Neuropsychiatr Genet. 2011 Sep; 2011 Jun 8. PMID: 21656904

Han S, Yang BZ, Kranzler HR, Oslin D, Anton R, Gelernter J: Association of CHRNA4 polymorphisms with smoking behavior in two populations. Am J Med Genet B Neuropsychiatr Genet. 2011 Jun; 2011 Mar 28. PMID: 21445957

Cui D, Zhang H, Yang BZ, Listman JB, Li D, Price LH, Carpenter LL, Tyrka AR, Anton RF, Kranzler HR, Gelernter J: Variation in NGFB is associated with primary affective disorders in women. Am J Med Genet B Neuropsychiatr Genet. 2011 Jun; 2011 Feb 3. PMID: 21294249

Stein MB, Yang BZ, Chavira DA, Hitchcock CA, Sung SC, Shipon-Blum E, Gelernter J: A common genetic variant in the neurexin superfamily member CNTNAP2 is associated with increased risk for selective mutism and social anxiety-related traits. Biol Psychiatry. 2011 May 1; 2010 Dec 30. PMID: 21193173

Gelernter J: Developmental perspective on the role of genes in smoking risk. Biol Psychiatry. 2011 Apr 1. PMID: 21397743

Listman JB, Malison RT, Sanichwankul K, Ittiwut C, Mutirangura A, Gelernter J: Southeast Asian origins of five Hill Tribe populations and correlation of genetic to linguistic relationships inferred with genome-wide SNP data. Am J Phys Anthropol. 2011 Feb. PMID: 20979205

Malison RT, Kalayasiri R, Sanichwankul K, Sughondhabirom A, Mutirangura A, Pittman B, Gueorguieva R, Kranzler HR, Gelernter J: Inter-rater reliability and concurrent validity of DSM-IV opioid dependence in a Hmong isolate using the Thai version of the Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA). Addict Behav. 2011 Jan-Feb. PMID: 20888699

Zhang H, Kranzler HR, Poling J, Gelernter J: Variation in the nicotinic acetylcholine receptor gene cluster CHRNA5-CHRNA3-CHRNB4 and its interaction with recent tobacco use influence cognitive flexibility. Neuropsychopharmacology. 2010 Oct; 2010 Jul 14. PMID: 20631687

Saccone NL, Culverhouse RC, Schwantes-An TH, Cannon DS, Chen X, Cichon S, Giegling I, Han S, Han Y, Keskitalo-Vuokko K, Kong X, Landi MT, Ma JZ, Short SE, Stephens SH, Stevens VL, Sun L, Wang Y, Wenzlaff AS, Aggen SH, Breslau N, Broderick P, Chatterjee N, Chen J, Heath AC, Heliövaara M, Hoft NR, Hunter DJ, Jensen MK, Martin NG, Montgomery GW, Niu T, Payne TJ, Peltonen L, Pergadia ML, Rice JP, Sherva R, Spitz MR, Sun J, Wang JC, Weiss RB, Wheeler W, Witt SH, Yang BZ, Caporaso NE, Ehringer MA, Eisen T, Gapstur SM, Gelernter J, Houlston R, Kaprio J, Kendler KS, Kraft P, Leppert MF, Li MD, Madden PA, Nöthen MM, Pillai S, Rietschel M, Rujescu D, Schwartz A, Amos CI, Bierut LJ: Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet. 2010 Aug 5; 2010 Aug 5. PMID: 20700436

Sherva R, Kranzler HR, Yu Y, Logue MW, Poling J, Arias AJ, Anton RF, Oslin D, Farrer LA, Gelernter J: Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes. Neuropsychopharmacology. 2010 Aug; 2010 May 19. PMID: 20485328

Xie P, Kranzler HR, Poling J, Stein MB, Anton RF, Farrer LA, Gelernter J: Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder. Neuropsychopharmacology. 2010 Jul; 2010 Apr 14. PMID: 20393453

Listman JB, Hasin D, Kranzler HR, Malison RT, Mutirangura A, Sughondhabirom A, Aharonovich E, Spivak B, Gelernter J: Identification of population substructure among Jews using STR markers and dependence on reference populations included. BMC Genet. 2010 Jun 14; 2010 Jun 14. PMID: 20546593

Zhang H, Gelernter J, Gruen JR, Kranzler HR, Herman AI, Simen AA: Functional impact of a single-nucleotide polymorphism in the OPRD1 promoter region. J Hum Genet. 2010 May; 2010 Mar 19. PMID: 20300121

Panhuysen CI, Kranzler HR, Yu Y, Weiss RD, Brady K, Poling J, Farrer LA, Gelernter J: Confirmation and generalization of an alcohol-dependence locus on chromosome 10q. Neuropsychopharmacology. 2010 May; 2010 Feb 10. PMID: 20147890

Zuo L, Gelernter J, Kranzler HR, Stein MB, Zhang H, Wei F, Sen S, Poling J, Luo X: ADH1A variation predisposes to personality traits and substance dependence. Am J Med Genet B Neuropsychiatr Genet. 2010 Mar 5. PMID: 19526455

Amstadter AB, Koenen KC, Ruggiero KJ, Acierno R, Galea S, Kilpatrick DG, Gelernter J: NPY moderates the relation between hurricane exposure and generalized anxiety disorder in an epidemiologic sample of hurricane-exposed adults. Depress Anxiety. 2010 Mar. PMID: 20037921

Amin Z, Kanarek K, Krupitsky E, Walderhaug E, Ilomäki R, Blumberg H, Price LH, Bhagwagar Z, Carpenter LL, Tyrka AR, Magnusson A, Landrø NI, Zvartau E, Gelernter J, Epperson CN, Räsänen P, Siironen J, Lappalainen J: A sequencing-based survey of functional APAF1 alleles in a large sample of individuals with affective illness and population controls. Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 5. PMID: 19455599

Han S, Gelernter J, Luo X, Yang BZ: Meta-analysis of 15 genome-wide linkage scans of smoking behavior. Biol Psychiatry. 2010 Jan 1. PMID: 19819424

Gelernter J, Kranzler HR: Genetics of drug dependence. Dialogues Clin Neurosci. 2010. PMID: 20373669

Zuo L, Luo X, Kranzler HR, Lu L, Rosenheck RA, Cramer J, van Kammen DP, Erdos J, Charney DS, Krystal J, Gelernter J: Association study of DTNBP1 with schizophrenia in a US sample. Psychiatr Genet. 2009 Dec. PMID: 19862852

Xie P, Kranzler HR, Poling J, Stein MB, Anton RF, Brady K, Weiss RD, Farrer L, Gelernter J: Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations. Arch Gen Psychiatry. 2009 Nov. PMID: 19884608

Zhang H, Kranzler HR, Poling J, Gruen JR, Gelernter J: Cognitive flexibility is associated with KIBRA variant and modulated by recent tobacco use. Neuropsychopharmacology. 2009 Nov; 2009 Jul 15. PMID: 19606085

Stein MB, Campbell-Sills L, Gelernter J: Genetic variation in 5HTTLPR is associated with emotional resilience. Am J Med Genet B Neuropsychiatr Genet. 2009 Oct 5. PMID: 19152387

Niciu MJ, Chan G, Gelernter J, Arias AJ, Douglas K, Weiss R, Anton RF, Farrer L, Cubells JF, Kranzler HR: Subtypes of major depression in substance dependence. Addiction. 2009 Oct; 2009 Aug 4. PMID: 19681804

Tang YL, Kranzler HR, Gelernter J, Farrer LA, Pearson D, Cubells JF: Transient cocaine-associated behavioral symptoms rated with a new instrument, the scale for assessment of positive symptoms for cocaine-induced psychosis (SAPS-CIP). Am J Addict. 2009 Sep-Oct. PMID: 19874151

Halder I, Yang BZ, Kranzler HR, Stein MB, Shriver MD, Gelernter J: Measurement of admixture proportions and description of admixture structure in different U.S. populations. Hum Mutat. 2009 Sep. PMID: 19572378

Zhang H, Kranzler HR, Weiss RD, Luo X, Brady KT, Anton RF, Farrer LA, Gelernter J: Pro-opiomelanocortin gene variation related to alcohol or drug dependence: evidence and replications across family- and population-based studies. Biol Psychiatry. 2009 Jul 15; 2009 Feb 12. PMID: 19217079

Gelernter J, Kranzler HR: Genetics of alcohol dependence. Hum Genet. 2009 Jul; 2009 Jun 17. PMID: 19533172

Zuo L, Luo X, Listman JB, Kranzler HR, Wang S, Anton RF, Blumberg HP, Stein MB, Pearlson GD, Covault J, Charney DS, van Kammen DP, Price LH, Lappalainen J, Cramer J, Krystal JH, Gelernter J: Population admixture modulates risk for alcohol dependence. Hum Genet. 2009 Jun; 2009 Mar 22. PMID: 19306106

Zuo L, Luo X, Krystal JH, Cramer J, Charney DS, Gelernter J: The efficacies of clozapine and haloperidol in refractory schizophrenia are related to DTNBP1 variation. Pharmacogenet Genomics. 2009 Jun. PMID: 19369910

Feinn R, Gelernter J, Cubells JF, Farrer L, Kranzler HR: Sources of unreliability in the diagnosis of substance dependence. J Stud Alcohol Drugs. 2009 May. PMID: 19371499

Zuo L, Kranzler HR, Luo X, Yang BZ, Weiss R, Brady K, Poling J, Farrer L, Gelernter J: Interaction between two independent CNR1 variants increases risk for cocaine dependence in European Americans: a replication study in family-based sample and population-based sample. Neuropsychopharmacology. 2009 May; 2008 Dec 3. PMID: 19052543

Jacobsen LK, Picciotto MR, Heath CJ, Mencl WE, Gelernter J: Allelic variation of calsyntenin 2 (CLSTN2) modulates the impact of developmental tobacco smoke exposure on mnemonic processing in adolescents. Biol Psychiatry. 2009 Apr 15; 2008 Dec 5. PMID: 19058786

Amstadter AB, Koenen KC, Ruggiero KJ, Acierno R, Galea S, Kilpatrick DG, Gelernter J: Variant in RGS2 moderates posttraumatic stress symptoms following potentially traumatic event exposure. J Anxiety Disord. 2009 Apr; 2008 Dec 25. PMID: 19162436

Farrer LA, Kranzler HR, Yu Y, Weiss RD, Brady KT, Anton R, Cubells JF, Gelernter J: Association of variants in MANEA with cocaine-related behaviors. Arch Gen Psychiatry. 2009 Mar. PMID: 19255376

Weder N, Yang BZ, Douglas-Palumberi H, Massey J, Krystal JH, Gelernter J, Kaufman J: MAOA genotype, maltreatment, and aggressive behavior: the changing impact of genotype at varying levels of trauma. Biol Psychiatry. 2009 Mar 1; 2008 Nov 8. PMID: 18996506

Han S, Ma L, Li D, Yang BZ: Is the tail-strength measure more powerful in tests of genetic association? Am J Hum Genet. 2009 Feb. PMID: 19215734

Gelernter J, Kranzler HR, Panhuysen C, Weiss RD, Brady K, Poling J, Farrer L: Dense genomewide linkage scan for alcohol dependence in African Americans: significant linkage on chromosome 10. Biol Psychiatry. 2009 Jan 15; 2008 Oct 18. PMID: 18930185

Amstadter AB, Koenen KC, Ruggiero KJ, Acierno R, Galea S, Kilpatrick DG, Gelernter J: Variation in RGS2 is associated with suicidal ideation in an epidemiological study of adults exposed to the 2004 Florida hurricanes. Arch Suicide Res. 2009. PMID: 19813112

Koenen KC, Amstadter AB, Ruggiero KJ, Acierno R, Galea S, Kilpatrick DG, Gelernter J: RGS2 and generalized anxiety disorder in an epidemiologic sample of hurricane-exposed adults. Depress Anxiety. 2009. PMID: 18833580

Zdanys KF, Kleiman TG, Zhang H, Ozbay F, MacAvoy MG, Gelernter J, van Dyck CH: BDNF variants, premorbid educational attainment, and disease characteristics in Alzheimer's disease: an exploratory study. J Alzheimers Dis. 2009. PMID: 19542613

Hirunsatit R, George ED, Lipska BK, Elwafi HM, Sander L, Yrigollen CM, Gelernter J, Grigorenko EL, Lappalainen J, Mane S, Nairn AC, Kleinman JE, Simen AA: Twenty-one-base-pair insertion polymorphism creates an enhancer element and potentiates SLC6A1 GABA transporter promoter activity. Pharmacogenet Genomics. 2009 Jan. PMID: 19077666

Amstadter AB, Nugent NR, Koenen KC, Ruggiero KJ, Acierno R, Galea S, Kilpatrick DG, Gelernter J: Association between COMT, PTSD, and increased smoking following hurricane exposure in an epidemiologic sample. Psychiatry. 2009 Winter. PMID: 20070134

Budel S, Padukkavidana T, Liu BP, Feng Z, Hu F, Johnson S, Lauren J, Park JH, McGee AW, Liao J, Stillman A, Kim JE, Yang BZ, Sodi S, Gelernter J, Zhao H, Hisama F, Arnsten AF, Strittmatter SM: Genetic variants of Nogo-66 receptor with possible association to schizophrenia block myelin inhibition of axon growth. J Neurosci. 2008 Dec 3. PMID: 19052207

Yang BZ, Kranzler HR, Zhao H, Gruen JR, Luo X, Gelernter J: Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence. Alcohol Clin Exp Res. 2008 Dec; 2008 Sep 30. PMID: 18828801

Blumberg HP, Wang F, Chepenik LG, Kalmar JH, Edmiston E, Duman RS, Gelernter J: Influence of vascular endothelial growth factor variation on human hippocampus morphology. Biol Psychiatry. 2008 Nov 15; 2008 Aug 15. PMID: 18707678

Luo X, Zuo L, Kranzler H, Zhang H, Wang S, Gelernter J: Multiple OPR genes influence personality traits in substance dependent and healthy subjects in two American populations. Am J Med Genet B Neuropsychiatr Genet. 2008 Oct 5. PMID: 18213616

Potenza MN, Brodkin ES, Yang BZ, Birnbaum SG, Nestler EJ, Gelernter J: Quantitative trait locus analysis identifies rat genomic regions related to amphetamine-induced locomotion and Galpha(i3) levels in nucleus accumbens. Neuropsychopharmacology. 2008 Oct; 2008 Jan 23. PMID: 18216777

Luo X, Zuo L, Kranzler HR, Wang S, Anton RF, Gelernter J: Recessive genetic mode of an ADH4 variant in substance dependence in African-Americans: A model of utility of the HWD test. Behav Brain Funct. 2008 Sep 18; 2008 Sep 18. PMID: 18801187

Hodgkinson CA, Yuan Q, Xu K, Shen PH, Heinz E, Lobos EA, Binder EB, Cubells J, Ehlers CL, Gelernter J, Mann J, Riley B, Roy A, Tabakoff B, Todd RD, Zhou Z, Goldman D: Addictions biology: haplotype-based analysis for 130 candidate genes on a single array. Alcohol Alcohol. 2008 Sep-Oct; 2008 May 12. PMID: 18477577

Yu Y, Kranzler HR, Panhuysen C, Weiss RD, Poling J, Farrer LA, Gelernter J: Substance dependence low-density whole genome association study in two distinct American populations. Hum Genet. 2008 Jun; 2008 Apr 26. PMID: 18438686

Zhang H, Kranzler HR, Yang BZ, Luo X, Gelernter J: The OPRD1 and OPRK1 loci in alcohol or drug dependence: OPRD1 variation modulates substance dependence risk. Mol Psychiatry. 2008 May; 2007 Jul 10. PMID: 17622222

Luo X, Kranzler HR, Zuo L, Zhang H, Wang S, Gelernter J: ADH7 variation modulates extraversion and conscientiousness in substance-dependent subjects. Am J Med Genet B Neuropsychiatr Genet. 2008 Mar 5. PMID: 17918242

Covault J, Gelernter J, Jensen K, Anton R, Kranzler HR: Markers in the 5'-region of GABRG1 associate to alcohol dependence and are in linkage disequilibrium with markers in the adjacent GABRA2 gene. Neuropsychopharmacology. 2008 Mar; 2007 May 16. PMID: 17507911

Kranzler HR, Wilcox M, Weiss RD, Brady K, Hesselbrock V, Rounsaville B, Farrer L, Gelernter J: The validity of cocaine dependence subtypes. Addict Behav. 2008 Jan; 2007 May 24. PMID: 17582692

Ittiwut C, Listman J, Mutirangura A, Malison R, Covault J, Kranzler HR, Sughondhabirom A, Thavichachart N, Gelernter J: Interpopulation linkage disequilibrium patterns of GABRA2 and GABRG1 genes at the GABA cluster locus on human chromosome 4. Genomics. 2008 Jan; 2007 Nov 5. PMID: 17976953

Stein MB, Schork NJ, Gelernter J: Gene-by-environment (serotonin transporter and childhood maltreatment) interaction for anxiety sensitivity, an intermediate phenotype for anxiety disorders. Neuropsychopharmacology. 2008 Jan; 2007 Apr 25. PMID: 17460615

Yang BZ, Kranzler HR, Zhao H, Gruen JR, Luo X, Gelernter J: Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case control and family samples. Hum Mol Genet. 2007 Dec 1; 2007 Aug 30. PMID: 17761687

Hernandez-Avila CA, Covault J, Wand G, Zhang H, Gelernter J, Kranzler HR: Population-specific effects of the Asn40Asp polymorphism at the mu-opioid receptor gene (OPRM1) on HPA-axis activation. Pharmacogenet Genomics. 2007 Dec. PMID: 18004207

Pierucci-Lagha A, Gelernter J, Chan G, Arias A, Cubells JF, Farrer L, Kranzler HR: Reliability of DSM-IV diagnostic criteria using the semi-structured assessment for drug dependence and alcoholism (SSADDA). Drug Alcohol Depend. 2007 Nov 2; 2007 Jun 27. PMID: 17590536

Kilpatrick DG, Koenen KC, Ruggiero KJ, Acierno R, Galea S, Resnick HS, Roitzsch J, Boyle J, Gelernter J: The serotonin transporter genotype and social support and moderation of posttraumatic stress disorder and depression in hurricane-exposed adults. Am J Psychiatry. 2007 Nov. PMID: 17974934

Hirunsatit R, Ilomäki R, Malison R, Räsänen P, Ilomäki E, Kranzler HR, Kosten T, Sughondhabirom A, Thavichachart N, Tangwongchai S, Listman J, Mutirangura A, Gelernter J, Lappalainen J: Sequence variation and linkage disequilibrium in the GABA transporter-1 gene (SLC6A1) in five populations: implications for pharmacogenetic research. BMC Genet. 2007 Oct 17; 2007 Oct 17. PMID: 17941974

Zuo L, Kranzler HR, Luo X, Covault J, Gelernter J: CNR1 variation modulates risk for drug and alcohol dependence. Biol Psychiatry. 2007 Sep 15; 2007 May 23. PMID: 17509535

Tang YL, Kranzler HR, Gelernter J, Farrer LA, Cubells JF: Comorbid psychiatric diagnoses and their association with cocaine-induced psychosis in cocaine-dependent subjects. Am J Addict. 2007 Sep-Oct. PMID: 17882604

Luo X, Kranzler HR, Zuo L, Zhang H, Wang S, Gelernter J: CHRM2 variation predisposes to personality traits of agreeableness and conscientiousness. Hum Mol Genet. 2007 Jul 1; 2007 Apr 27. PMID: 17468496

Kalayasiri R, Sughondhabirom A, Gueorguieva R, Coric V, Lynch WJ, Lappalainen J, Gelernter J, Cubells JF, Malison RT: Dopamine beta-hydroxylase gene (DbetaH) -1021C-->T influences self-reported paranoia during cocaine self-administration. Biol Psychiatry. 2007 Jun 1; 2006 Dec 6. PMID: 17157269

Kaufman J, Yang BZ, Douglas-Palumberi H, Crouse-Artus M, Lipschitz D, Krystal JH, Gelernter J: Genetic and environmental predictors of early alcohol use. Biol Psychiatry. 2007 Jun 1; 2006 Nov 21. PMID: 17123474

Listman JB, Malison RT, Sughondhabirom A, Yang BZ, Raaum RL, Thavichachart N, Sanichwankul K, Kranzler HR, Tangwonchai S, Mutirangura A, Disotell TR, Gelernter J: Demographic changes and marker properties affect detection of human population differentiation. BMC Genet. 2007 May 11; 2007 May 11. PMID: 17498298

Gelernter J, Gueorguieva R, Kranzler HR, Zhang H, Cramer J, Rosenheck R, Krystal JH, VA Cooperative Study #425 Study Group.: Opioid receptor gene (OPRM1, OPRK1, and OPRD1) variants and response to naltrexone treatment for alcohol dependence: results from the VA Cooperative Study. Alcohol Clin Exp Res. 2007 Apr. PMID: 17374034

Lappalainen J, Krupitsky E, Kranzler HR, Luo X, Remizov M, Pchelina S, Taraskina A, Zvartau E, Räsanen P, Makikyro T, Somberg LK, Krystal JH, Stein MB, Gelernter J: Mutation screen of the GAD2 gene and association study of alcoholism in three populations. Am J Med Genet B Neuropsychiatr Genet. 2007 Mar 5. PMID: 17034009

Luo X, Kranzler HR, Zuo L, Wang S, Gelernter J: Personality traits of agreeableness and extraversion are associated with ADH4 variation. Biol Psychiatry. 2007 Mar 1; 2006 Oct 25. PMID: 17069770

Luo X, Kranzler HR, Zuo L, Wang S, Schork NJ, Gelernter J: Multiple ADH genes modulate risk for drug dependence in both African- and European-Americans. Hum Mol Genet. 2007 Feb 15; 2006 Dec 21. PMID: 17185388

Gelernter J, Panhuysen C, Weiss R, Brady K, Poling J, Krauthammer M, Farrer L, Kranzler HR: Genomewide linkage scan for nicotine dependence: identification of a chromosome 5 risk locus. Biol Psychiatry. 2007 Jan 1; 2006 Nov 1. PMID: 17081504

Gelernter J, Yu Y, Weiss R, Brady K, Panhuysen C, Yang BZ, Kranzler HR, Farrer L: Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations. Hum Mol Genet. 2006 Dec 15; 2006 Nov 3. PMID: 17085484

Zhang H, Ye Y, Wang X, Gelernter J, Ma JZ, Li MD: DOPA decarboxylase gene is associated with nicotine dependence. Pharmacogenomics. 2006 Dec. PMID: 17184203

Malison RT, Kranzler HR, Yang BZ, Gelernter J: Human clock, PER1 and PER2 polymorphisms: lack of association with cocaine dependence susceptibility and cocaine-induced paranoia. Psychiatr Genet. 2006 Dec. PMID: 17106427

Jacobsen LK, Pugh KR, Mencl WE, Gelernter J: C957T polymorphism of the dopamine D2 receptor gene modulates the effect of nicotine on working memory performance and cortical processing efficiency. Psychopharmacology (Berl). 2006 Nov; 2006 Aug 9. PMID: 16896957

Krystal JH, Staley J, Mason G, Petrakis IL, Kaufman J, Harris RA, Gelernter J, Lappalainen J: Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment. Arch Gen Psychiatry. 2006 Sep. PMID: 16952998

Kalayasiri R, Kranzler HR, Weiss R, Brady K, Gueorguieva R, Panhuysen C, Yang BZ, Farrer L, Gelernter J, Malison RT: Risk factors for cocaine-induced paranoia in cocaine-dependent sibling pairs. Drug Alcohol Depend. 2006 Sep 1; 2006 Jan 18. PMID: 16413147

Yu Y, Panhuysen C, Kranzler HR, Hesselbrock V, Rounsaville B, Weiss R, Brady K, Farrer LA, Gelernter J: Intronic variants in the dopa decarboxylase (DDC) gene are associated with smoking behavior in European-Americans and African-Americans. Hum Mol Genet. 2006 Jul 15; 2006 Jun 1. PMID: 16740595

Herman AI, Kranzler HR, Cubells JF, Gelernter J, Covault J: Association study of the CNR1 gene exon 3 alternative promoter region polymorphisms and substance dependence. Am J Med Genet B Neuropsychiatr Genet. 2006 Jul 5. PMID: 16741937

Stein MB, Seedat S, Gelernter J: Serotonin transporter gene promoter polymorphism predicts SSRI response in generalized social anxiety disorder. Psychopharmacology (Berl). 2006 Jul; 2006 Mar 9. PMID: 16525856

Zhang H, Ozbay F, Lappalainen J, Kranzler HR, van Dyck CH, Charney DS, Price LH, Southwick S, Yang BZ, Rasmussen A, Gelernter J: Brain derived neurotrophic factor (BDNF) gene variants and Alzheimer's disease, affective disorders, posttraumatic stress disorder, schizophrenia, and substance dependence. Am J Med Genet B Neuropsychiatr Genet. 2006 Jun 5. PMID: 16649215

Luo X, Kranzler HR, Zuo L, Wang S, Schork NJ, Gelernter J: Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence. Am J Hum Genet. 2006 Jun; 2006 Apr 11. PMID: 16685648

Gelernter J, Panhuysen C, Wilcox M, Hesselbrock V, Rounsaville B, Poling J, Weiss R, Sonne S, Zhao H, Farrer L, Kranzler HR: Genomewide linkage scan for opioid dependence and related traits. Am J Hum Genet. 2006 May; 2006 Mar 16. PMID: 16642432

Luo X, Kranzler HR, Zuo L, Lappalainen J, Yang BZ, Gelernter J: ADH4 gene variation is associated with alcohol dependence and drug dependence in European Americans: results from HWD tests and case-control association studies. Neuropsychopharmacology. 2006 May. PMID: 16237392

Kaufman J, Yang BZ, Douglas-Palumberi H, Grasso D, Lipschitz D, Houshyar S, Krystal JH, Gelernter J: Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children. Biol Psychiatry. 2006 Apr 15; 2006 Feb 3. PMID: 16458264

Zuo L, van Dyck CH, Luo X, Kranzler HR, Yang BZ, Gelernter J: Variation at APOE and STH loci and Alzheimer's disease. Behav Brain Funct. 2006 Apr 7; 2006 Apr 7. PMID: 16603077

Zhang H, Luo X, Kranzler HR, Lappalainen J, Yang BZ, Krupitsky E, Zvartau E, Gelernter J: Association between two mu-opioid receptor gene (OPRM1) haplotype blocks and drug or alcohol dependence. Hum Mol Genet. 2006 Mar 15; 2006 Feb 13. PMID: 16476706

Dahl JP, Cubells JF, Ray R, Weller AE, Lohoff FW, Ferraro TN, Oslin DW, Kampman KM, Dackis C, Tang Y, Gelernter J, Kranzler HR, O'Brien CP, Berrettini WH: Analysis of variations in the tryptophan hydroxylase-2 (TPH2) gene in cocaine dependence. Addict Biol. 2006 Mar. PMID: 16759340

Pierucci-Lagha A, Gelernter J, Feinn R, Cubells JF, Pearson D, Pollastri A, Farrer L, Kranzler HR: Diagnostic reliability of the Semi-structured Assessment for Drug Dependence and Alcoholism (SSADDA). Drug Alcohol Depend. 2005 Dec 12. PMID: 15896927

Pollastri AR, Pokrywa ML, Walsh SJ, Kranzler HR, Gelernter J: Incentive program decreases no-shows in nontreatment substance abuse research. Exp Clin Psychopharmacol. 2005 Nov. PMID: 16366768

Stein MB, Fallin MD, Schork NJ, Gelernter J: COMT polymorphisms and anxiety-related personality traits. Neuropsychopharmacology. 2005 Nov. PMID: 15956988

Luo X, Kranzler HR, Zuo L, Yang BZ, Lappalainen J, Gelernter J: ADH4 gene variation is associated with alcohol and drug dependence: results from family controlled and population-structured association studies. Pharmacogenet Genomics. 2005 Nov. PMID: 16220108

Yang BZ, Zhao H, Kranzler HR, Gelernter J: Characterization of a likelihood based method and effects of markers informativeness in evaluation of admixture and population group assignment. BMC Genet. 2005 Oct 14; 2005 Oct 14. PMID: 16225681

Cubells JF, Feinn R, Pearson D, Burda J, Tang Y, Farrer LA, Gelernter J, Kranzler HR: Rating the severity and character of transient cocaine-induced delusions and hallucinations with a new instrument, the Scale for Assessment of Positive Symptoms for Cocaine-Induced Psychosis (SAPS-CIP). Drug Alcohol Depend. 2005 Oct 1. PMID: 15894433

Luo X, Kranzler HR, Zuo L, Wang S, Blumberg HP, Gelernter J: CHRM2 gene predisposes to alcohol dependence, drug dependence and affective disorders: results from an extended case-control structured association study. Hum Mol Genet. 2005 Aug 15; 2005 Jul 6. PMID: 16000316

Gelernter J, Panhuysen C, Weiss R, Brady K, Hesselbrock V, Rounsaville B, Poling J, Wilcox M, Farrer L, Kranzler HR: Genomewide linkage scan for cocaine dependence and related traits: significant linkages for a cocaine-related trait and cocaine-induced paranoia. Am J Med Genet B Neuropsychiatr Genet. 2005 Jul 5. PMID: 15909294

Yang BZ, Zhao H, Kranzler HR, Gelernter J: Practical population group assignment with selected informative markers: characteristics and properties of Bayesian clustering via STRUCTURE. Genet Epidemiol. 2005 May. PMID: 15782414

van Dyck CH, Malison RT, Jacobsen LK, Seibyl JP, Staley JK, Laruelle M, Baldwin RM, Innis RB, Gelernter J: Increased dopamine transporter availability associated with the 9-repeat allele of the SLC6A3 gene. J Nucl Med. 2005 May. PMID: 15872345

Lappalainen J, Krupitsky E, Remizov M, Pchelina S, Taraskina A, Zvartau E, Somberg LK, Covault J, Kranzler HR, Krystal JH, Gelernter J: Association between alcoholism and gamma-amino butyric acid alpha2 receptor subtype in a Russian population. Alcohol Clin Exp Res. 2005 Apr. PMID: 15834213

Kaufman J, Yang BZ, Douglas-Palumberi H, Houshyar S, Lipschitz D, Krystal JH, Gelernter J: Social supports and serotonin transporter gene moderate depression in maltreated children. Proc Natl Acad Sci U S A. 2004 Dec 7; 2004 Nov 24. PMID: 15563601

Stein MB, Schork NJ, Gelernter J: A polymorphism of the beta1-adrenergic receptor is associated with low extraversion. Biol Psychiatry. 2004 Aug 15. PMID: 15312808

Gelernter J, Liu X, Hesselbrock V, Page GP, Goddard A, Zhang H: Results of a genomewide linkage scan: support for chromosomes 9 and 11 loci increasing risk for cigarette smoking. Am J Med Genet B Neuropsychiatr Genet. 2004 Jul 1. PMID: 15211640

Berrettini W, Bierut L, Crowley TJ, Cubells JF, Frascella J, Gelernter J, Hewitt JK, Kreek MJ, Lachman H, Leppert M, Li MD, Madden P, Miner C, Pollock JD, Pomerleau O, Rice JP, Rutter JL, Shurtleff D, Swan GE, Tischfield JA, Tsuang M, Uhl GR, Vanyukov M, Volkow ND, Wanke K: Setting priorities for genomic research. Science. 2004 Jun 4. PMID: 15178784

Potenza MN, Brodkin ES, Joe B, Luo X, Remmers EF, Wilder RL, Nestler EJ, Gelernter J: Genomic regions controlling corticosterone levels in rats. Biol Psychiatry. 2004 Mar 15. PMID: 15013833

van Dyck CH, Malison RT, Staley JK, Jacobsen LK, Seibyl JP, Laruelle M, Baldwin RM, Innis RB, Gelernter J: Central serotonin transporter availability measured with [123I]beta-CIT SPECT in relation to serotonin transporter genotype. Am J Psychiatry. 2004 Mar. PMID: 14992979

Lappalainen J, Kranzler HR, Petrakis I, Somberg LK, Page G, Krystal JH, Gelernter J: Confirmation and fine mapping of the chromosome 1 alcohol dependence risk locus. Mol Psychiatry. 2004 Mar. PMID: 15094791

Luo X, Kranzler H, Lappalainen J, Rosenheck R, Charney D, Zuo L, Erdos J, van Kammen DP, Gelernter J: CALCYON gene variation, schizophrenia, and cocaine dependence. Am J Med Genet B Neuropsychiatr Genet. 2004 Feb 15. PMID: 14755439

Luo X, Klempan TA, Lappalainen J, Rosenheck RA, Charney DS, Erdos J, van Kammen DP, Kranzler HR, Kennedy JL, Gelernter J: NOTCH4 gene haplotype is associated with schizophrenia in African Americans. Biol Psychiatry. 2004 Jan 15. PMID: 14732589

Lappalainen J, Sanacora G, Kranzler HR, Malison R, Hibbard ES, Price LH, Krystal J, Gelernter J: Mutation screen of the glutamate decarboxylase-67 gene and haplotype association to unipolar depression. Am J Med Genet B Neuropsychiatr Genet. 2004 Jan 1. PMID: 14681921

Gelernter J, Page GP, Stein MB, Woods SW: Genome-wide linkage scan for loci predisposing to social phobia: evidence for a chromosome 16 risk locus. Am J Psychiatry. 2004 Jan. PMID: 14702251