2021
Risk profiles for mental disorders
Gülöksüz S. Risk profiles for mental disorders. European Psychiatry 2021, 64: s71-s71. PMCID: PMC9471330, DOI: 10.1192/j.eurpsy.2021.220.Peer-Reviewed Original ResearchPsychiatric diagnosisSame psychiatric diagnosisDifferent psychiatric diagnosesSame treatment protocolClinical staging modelRisk profilingDiagnosis-specific treatmentsSame treatment planTreatment protocolTreatment responseMedical conditionsClinical practiceDiagnostic classification systemsTreatment planMental disordersStaging modelRisk profileDiscrete diagnostic categoriesPatientsDiagnostic categoriesClinical predictionDiagnosisEarly psychopathologyTraditional diagnostic boundariesPrognosticationAntipsychotics result in more weight gain in antipsychotic naive patients than in patients after antipsychotic switch and weight gain is irrespective of psychiatric diagnosis: A meta-analysis
Bak M, Drukker M, Cortenraad S, Vandenberk E, Guloksuz S. Antipsychotics result in more weight gain in antipsychotic naive patients than in patients after antipsychotic switch and weight gain is irrespective of psychiatric diagnosis: A meta-analysis. PLOS ONE 2021, 16: e0244944. PMID: 33596211, PMCID: PMC7888647, DOI: 10.1371/journal.pone.0244944.Peer-Reviewed Original ResearchConceptsAntipsychotic-naive patientsBody weight changesBody weight gainWeight gainPsychiatric diagnosisNaive patientsWeight changeAntipsychotic useBodyweight gainAntipsychotic-naive groupMore weight gainDiagnosis of schizophreniaAntipsychotic switchMost antipsychoticsShort followSwitch studyMetabolic disturbancesClinical trialsOutcome measuresAntipsychoticsPatientsBody weightNaive groupSwitch groupDiagnosis
2020
Predictive Performance of Exposome Score for Schizophrenia in the General Population
Pries L, Erzin G, van Os J, Have M, de Graaf R, van Dorsselaer S, Bak M, Rutten B, Guloksuz S. Predictive Performance of Exposome Score for Schizophrenia in the General Population. Schizophrenia Bulletin 2020, 47: 277-283. PMID: 33215211, PMCID: PMC7965069, DOI: 10.1093/schbul/sbaa170.Peer-Reviewed Original ResearchConceptsES-SCZOptimal cut pointGeneral populationPopulation cohortGeneral population cohortCut pointsExposome scoreSchizophrenia spectrum disordersMeta-analytical estimatesClinical outcomesRisk strataRisk stratificationMulticausal etiologyMedical outcomesPsychiatric diagnosisBipolar disorderSchizophrenia diagnosisExposure scoreSuicide planSum scoreGene-environment interaction studiesSchizophreniaRisk predictionCharacteristic curveScores