Estimating the Association Between Exposome and Psychosis as Well as General Psychopathology: Results From the ABCD Study
Pries L, Moore T, Visoki E, Sotelo I, Barzilay R, Guloksuz S. Estimating the Association Between Exposome and Psychosis as Well as General Psychopathology: Results From the ABCD Study. Biological Psychiatry Global Open Science 2022, 2: 283-291. PMID: 36325038, PMCID: PMC9616253, DOI: 10.1016/j.bpsgos.2022.05.005.Peer-Reviewed Original ResearchPregnancy/birth complicationsExposome factorsGeneral psychopathologyBirth complicationsCognitive Development StudyGeneral psychopathology factorAdolescent Brain Cognitive Development (ABCD) studyClinical symptomsAdjusted modelMultiple comparison correctionExposome approachLinear regression analysisMental disordersNeurodevelopmental psychopathologyChildhood adversityPsychosisEnvironmental exposuresABCD studyNongenetic factorsComplicationsRegression analysisPsychopathology factorNeighborhood environmentPsychopathologyExposomeModeling environment through a general exposome factor in two independent adolescent cohorts
Moore T, Visoki E, Argabright S, Didomenico G, Sotelo I, Wortzel J, Naeem A, Gur R, Gur R, Warrier V, Guloksuz S, Barzilay R. Modeling environment through a general exposome factor in two independent adolescent cohorts. Exposome 2022, 2: osac010. PMID: 36606125, PMCID: PMC9798749, DOI: 10.1093/exposome/osac010.Peer-Reviewed Original ResearchExposome factorsOverall psychopathologyAdolescent cohortPubertal developmentEnvironmental exposuresAdvanced pubertal developmentSex-matched sampleKey health-related outcomesHealth-related outcomesCognitive Development StudyAdolescent Brain Cognitive Development (ABCD) studyGeneral healthCohortPhiladelphia Neurodevelopmental CohortConsistent associationABCD studyObesityNeurodevelopmental CohortParental educationExposurePsychopathologyFactorsPhysical environmental stimuli