Research & Publications
Dr. Duman received his doctorate degree from the University
of Texas in Houston and conducted postgraduate work at Yale University before
joining the faculty there. He has written and/or co-authored over 300 original
papers, reviews and book chapters, and has presented over 250 invited lectures.
Dr. Duman is also on the editorial board of several prestigious journals and
serves as a consultant for a number of biotech and pharmaceutical companies.
Dr. Duman has received several awards for his work, including the Anna-Monika Prize, Nola Maddox Falcone Prize, Janssen Prize, NIMH MERIT Award, and a NARSAD Distinguished Investigator Award
Studies from Dr. Duman’s laboratory have contributed to characterization of the molecular and cellular actions of stress, depression, and antidepressant treatments, providing the basis for a neurotrophic and synaptic hypothesis of depression. He has also studied the role of the innate immune system in the pathophysiology and treatment of depression. These findings represent major advances in our understanding of the effects of antidepressants and provide a framework for the development of novel therapeutic agents.
Education & Training
- PhDUniversity of Texas (1984)
- Postdoctoral FellowYale University School of Medicine
- Postdoctoral FellowUniversity of Texas, Houston
- Molecular Mechanisms of Stress & AntidepressantsJapan 2008Ronald Duman is collaborating with a number of Japanese researchers to study the molecular and cellular mechanisms underlying the actions of stress and antidepressants.
- Neurotrophic Factors and AntidepressantsIndia 2008Professor Duman collaborates with a former student on the emphasis on the influence of early postnatal stress and the long-term effects of such stress on the adult animal. This focuses on interests in antidepressants and identifying mechanisms for developing better therapeutic agents. One of the actions that Dr. Duman has found is that antidepressants increase neurotrophic factors in the brain. Neurotrophic, as the name implies, means that these factors provide support for the survival as well as function of neurons. There is growing evidence, from their work, as well as others, that decreases in the survival and function of neurons contributes to depression and that antidepressants work in part by blocking or reversing these effects.
Honors & Recognition
|Elected to the National Academy of Medicine||National Academy of Medicine||2016|
|Congress of International Neuropsychopharmacology Research Award||CINP||2006|
|Dr. Paul Janssen Prize for Psychopharmacology||Janssen Pharmaceutical Company||2003|
|NARSAD-Nola Maddox Falcone Prize||NARSAD||2002|
|Anna-Monika Award for outstanding research in depression||Anna-Monika Foundation||2001|