2010
A multistudy analysis of the effects of early cocaine abstinence on sleep
Matuskey D, Pittman B, Forselius E, Malison RT, Morgan PT. A multistudy analysis of the effects of early cocaine abstinence on sleep. Drug And Alcohol Dependence 2010, 115: 62-66. PMID: 21144676, PMCID: PMC3081928, DOI: 10.1016/j.drugalcdep.2010.10.015.Peer-Reviewed Original Research
2008
Sleep architecture, cocaine and visual learning
Morgan PT, Pace‐Schott E, Sahul ZH, Coric V, Stickgold R, Malison RT. Sleep architecture, cocaine and visual learning. Addiction 2008, 103: 1344-1352. PMID: 18855824, PMCID: PMC3690941, DOI: 10.1111/j.1360-0443.2008.02233.x.Peer-Reviewed Original ResearchConceptsChronic cocaine usersVisual learningProgressive abstinenceVisual texture discrimination taskLate night REM sleepSlow wave activityAbstinence-related changesTexture discrimination taskCocaine usersSleep architectureCocaine useVisual performanceREM sleepOvernight enhancementDays of abstinenceDiscrimination taskCocaine self-administration sessionsSelf-administration sessionsCognitive functionChronic cocaine useLearning deficitsCognitive dysfunctionRapid eye movement (REM) sleepAbstinenceCocaine abstinencePilot Study of Lorazepam and Tiagabine Effects on Sleep, Motor Learning, and Impulsivity in Cocaine Abstinence
Morgan PT, Malison RT. Pilot Study of Lorazepam and Tiagabine Effects on Sleep, Motor Learning, and Impulsivity in Cocaine Abstinence. The American Journal Of Drug And Alcohol Abuse 2008, 34: 692-702. PMID: 18850496, DOI: 10.1080/00952990802308221.Peer-Reviewed Original ResearchConceptsSleep-dependent learningCocaine-dependent personsEffects of lorazepamCognitive effectsCognitive functionMotor learningTotal sleep timeDependent learningImpulsivitySlow-wave sleepCocaine abstinenceSleep latencyAbstinenceSleep timeSleepDependent personsLearningLight sleepCognitionCocaine administrationSedative hypnoticsPilot studyLorazepamParticipantsDifferent GABA
2007
Altered levels of sex and stress steroid hormones assessed daily over a 28-day cycle in early abstinent cocaine-dependent females
Fox HC, Hong KA, Paliwal P, Morgan PT, Sinha R. Altered levels of sex and stress steroid hormones assessed daily over a 28-day cycle in early abstinent cocaine-dependent females. Psychopharmacology 2007, 195: 527-536. PMID: 17891383, PMCID: PMC2746368, DOI: 10.1007/s00213-007-0936-3.Peer-Reviewed Original ResearchConceptsMenstrual cycleSex hormonesHealthy femalesEstradiol/progesterone ratioSteroid hormonesFirst monthChronic cocaine abuseSex steroid hormonesLevels of cortisolMood rating scalesStress steroid hormonesDrug-seeking behaviorProgesterone ratioHealthy controlsInpatient treatmentObjectivesThe current studyEvidence of alterationsBrain stressCocaine cravingCocaine abuseSalivary samplesCocaine abstinenceCocaine dependenceCocaine reinforcementCocaine patients