2024
Neural correlates of altered emotional responsivity to infant stimuli in mothers who use substances
McCurdy L, Yip S, Worhunsky P, Zhai Z, Kim S, Strathearn L, Potenza M, Mayes L, Rutherford H. Neural correlates of altered emotional responsivity to infant stimuli in mothers who use substances. Journal Of Psychiatric Research 2024, 171: 126-133. PMID: 38277872, PMCID: PMC10922955, DOI: 10.1016/j.jpsychires.2024.01.024.Peer-Reviewed Original ResearchMeSH KeywordsBrainChildEmotionsFemaleHumansInfantMagnetic Resonance ImagingMaternal BehaviorMother-Child RelationsMothersConceptsResponses to infant stimuliInfant stimuliMaternal behaviorAffective processesBrain regionsPsychological processesEmotional responsesFunctional magnetic resonance imagingPotential neural targetsInfant emotional expressionsMaternal emotional responsivenessSubstance-use statusAssociated with difficultiesSocial-emotional developmentInfant social-emotional developmentMaternal substance useInfant facesCognitive processesImprove child outcomesEmotional expressionEmotional intensityNeural targetsSubstance useGroups of mothersChild outcomes
2019
Neurofunctional Differences Related to Methamphetamine and Sexual Cues in Men With Shorter and Longer Term Abstinence Methamphetamine Dependence
Chen S, Huang S, Yang C, Cai W, Chen H, Hao W, Liu T, Wang X, Worhunsky P, Potenza M. Neurofunctional Differences Related to Methamphetamine and Sexual Cues in Men With Shorter and Longer Term Abstinence Methamphetamine Dependence. The International Journal Of Neuropsychopharmacology 2019, 23: 135-145. PMID: 31995187, PMCID: PMC7171928, DOI: 10.1093/ijnp/pyz069.Peer-Reviewed Original ResearchConceptsHealthy comparison menFrontal cortex activationLong-term methamphetamine abstinenceSexual cuesNeutral cuesMethamphetamine cuesNeurofunctional differencesComparison menCortex activationLeft superior frontal cortexCue-related activationsNeutral visual cuesAnterior insula activationCue-reactivity taskAnterior insula responseVentromedial prefrontal cortexHealthy comparison participantsMethamphetamine abstinenceMethamphetamine dependenceFunctional magnetic resonanceWhole-brain analysisAbstinence groupSuperior frontal cortexInsula activationInsula response